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Hemosuccus Pancreaticus
A 47-year-old man with alcohol-related cirrhosis and chronic pancreatitis presented with hematemesis. Upper endoscopy and colonoscopy demonstrated blood in the proximal small bowel, without active bleeding. The patient was hospitalized for 29 days for obscure gastrointestinal hemorrhage with intermittent episodes of hematemesis and hematochezia, for which 8 upper endoscopies, 3 colonoscopies, and 5 tagged red blood cell scans were performed. An image from final endoscopy performed in the intensive care unit for massive hematemesis demonstrated active bleeding emanating from the ampulla of Vater (Fig  1). (Source: Jour...
Source: Journal of Vascular and Interventional Radiology : JVIR - July 21, 2017 Category: Radiology Authors: Bo Liu, Francisco J. Contreras, Thomas J. Ward Tags: Images in IR Source Type: research

Gastric Hyperplastic Polyps Associated with Proton Pump Inhibitor Use in a Case without a History of Helicobacter pylori Infection.
Authors: Miyamoto S, Kato M, Matsuda K, Abiko S, Tsuda M, Mizushima T, Yamamoto K, Ono S, Kudo T, Shimizu Y, Hatanaka KC, Tsunematsu I, Sakamoto N Abstract A 56-year-old man with gastroesophageal reflux disease (GERD) was referred to our hospital. Esophagogastroduodenoscopy (EGD) revealed no evidence of any polypoid lesions in the stomach, and the patient had no history of Helicobacter pylori infection. He received omeprazole (20 mg) once daily for the GERD. EGD was performed at 1 year after the start of omeprazole administration, and this time, gastric hyperplastic polyps (GHPs) were detected. The GHPs increased i...
Source: Internal Medicine - July 20, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research

Clinical Significance of Spontaneous Pneumomediastinum
Conclusions Spontaneous pneumomediastinum is usually associated with a benign clinical course. Risk factors for esophageal perforation in these patients include age, elevated white blood cell count, and a pleural effusion. In the absence of abnormal laboratory values or associated radiologic findings, the majority of patients with SPM may be safely observed without the need for further diagnostic testing. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - July 20, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research

Which Factors Are Important for Successful Sentinel Node Navigation Surgery in Gastric Cancer Patients? Analysis from the SENORITA Prospective Multicenter Feasibility Quality Control Trial.
Authors: An JY, Min JS, Lee YJ, Jeong SH, Hur H, Han SU, Hyung WJ, Cho GS, Jeong GA, Jeong O, Park YK, Jung MR, Park JY, Kim YW, Yoon HM, Eom BW, Ryu KW Abstract BACKGROUND: We investigated the results of quality control study prior to phase III trial of sentinel lymph node navigation surgery (SNNS). METHODS: Data were reviewed from 108 patients enrolled in the feasibility study of laparoscopic sentinel basin dissection (SBD) in gastric cancer. Seven steps contain tracer injection at submucosa (step 1) and at four sites (step 2) by intraoperative esophagogastroduodenoscopy (EGD), leakage of tracer (step 3), inj...
Source: Gastroenterology Research and Practice - July 16, 2017 Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research

Impedance-pH Monitoring for Diagnosis of Reflux Disease: New Perspectives
AbstractHeartburn is the most specific symptom of gastroesophageal reflux disease (GERD). In clinical practice, heartburn relief by a proton pump inhibitor (PPI) trial does suffice to confirm GERD. However, an objective diagnosis of GERD is required before anti-reflux endoscopic or surgical interventions, independently from PPI response. Thus, since normal findings at upper endoscopy are detected in the majority of patients with heartburn, reflux monitoring is often required. When traditional catheter-based or wireless pH tests are used, reflux episodes are conventionally identified by pH drops below 4.0 units. Combined im...
Source: Digestive Diseases and Sciences - July 15, 2017 Category: Gastroenterology Source Type: research

Case Report on the Non-Operative Management of a Retrievable Inferior Vena Cava Filter Perforating the Duodenum
CONCLUSION For patients with significant comorbidities or patients who are poor surgical candidates, non-operative management with close monitoring can serve as an initial approach to the patient with a caval enteric perforation secondary to a retrievable IVC filter. (Source: International Journal of Surgery Case Reports)
Source: International Journal of Surgery Case Reports - July 10, 2017 Category: Surgery Source Type: research

Tracheopleural and esophagopleural fistula complicating corrosive-induced esophageal cancer
We describe the imaging findings of a tracheopleural and an esophagopleural fistula complicating a squamous cell esophageal carcinoma in a patient with human immunodeficiency virus with chronic esophageal strictures secondary to accidental caustic ingestion as a child. The esophageal cancer was diagnosed by an upper endoscopy after a thoracic computed tomography (CT) performed because of fever, malaise, and chest pain showed signs of esophageal perforation with mediastinitis and a right pneumothorax. (Source: Surgery)
Source: Surgery - July 10, 2017 Category: Surgery Authors: Luis Gorospe, Alberto Caba ñero-Sánchez, Gemma María Muñoz-Molina, David Saldaña-Garrido, Ana Patricia Ovejero-Díaz, Percy Carvajal-Serrano Tags: Images in Surgery Source Type: research

Associations between obstructive sleep apnea severity and endoscopically proven gastroesophageal reflux disease
ConclusionsEndoscopically proven GERD was associated with more severe OSA. GERD symptoms were also associated with deteriorated sleep quality. (Source: Sleep and Breathing)
Source: Sleep and Breathing - July 7, 2017 Category: Respiratory Medicine Source Type: research

Associations between obstructive sleep apnea severity and endoscopically proven gastroesophageal reflux disease.
CONCLUSIONS: Endoscopically proven GERD was associated with more severe OSA. GERD symptoms were also associated with deteriorated sleep quality. PMID: 28687968 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - July 7, 2017 Category: Sleep Medicine Authors: Kim Y, Lee YJ, Park JS, Cho YJ, Yoon HI, Lee JH, Lee CT, Kim SJ Tags: Sleep Breath Source Type: research

The Application of the Rome IV Criteria to Functional Esophagogastroduodenal Disorders in Asia.
Authors: Suzuki H Abstract The Rome criteria were amended as Rome IV. For functional esophageal disorders, the exclusion criteria have been more specifically revised based on further understanding of other esophageal disorders, including eosinophilic esophagitis and spastic and hypercontractile motor disorders. Another revised point is the more restrictive definition of gastroesophageal reflux disease, indicating that sensitivity to a physiological reflux burden may be placed more firmly within the functional group. For functional dyspepsia (FD), only minor changes were introduced, mainly to improve specificity. Am...
Source: Journal of Neurogastroenterology and Motility - July 6, 2017 Category: Gastroenterology Tags: J Neurogastroenterol Motil Source Type: research

Is Routine Preoperative Esophagogastroduodenscopy Screening Necessary Prior to Laparoscopic Sleeve Gastrectomy? Review of 1555 Cases and Comparison with Current Literature
ConclusionDue to effectiveness and best utilization of resources, routine p-OGD screening in patients scheduled for LSG may require further justification for asymptomatic patients especially in regions with low upper GI cancers. p-OGD findings had low impact on the management of asymptomatic patients. Crural repair plus LSG was effective for hiatal hernia. (Source: Obesity Surgery)
Source: Obesity Surgery - July 6, 2017 Category: Surgery Source Type: research

Is Colonoscopic Screening Necessary for Patients Younger than 50 Years with Gastric Adenoma or Cancer?
Abstract Patients, aged ≥ 50 years, with gastric neoplasm are reported to be at increased risk for colorectal neoplasia (CRN), while data regarding the risk of CRN in young patients, aged
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Kim NH, Park JH, Park DI, Sohn CI, Jung YS Tags: J Korean Med Sci Source Type: research

Concomitant stromal tumor and early cancer of the stomach: What should be done?
Abstract: Concomitant gastric stromal tumor (GST) and gastric cancer (GC) is uncommon; even more uncommon is a concomitant GST and early stage GC (EGC). Tumor resection by endoscopic submucosal dissection (ESD) for concomitant GST and EGC has not been reported. We sought to define the clinical importance of detection of concomitant GST and EGC during the first esophagogastroduodenoscopy (EGD), and compare the clinical outcomes of ESD versus radical surgery for the treatment of concomitant GST and EGC. Our investigation was a retrospective cohort study. Patients with concomitant GST and EGC who underwent ESD or radical surg...
Source: Medicine - July 1, 2017 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Diagnostic performance of routine esophagogastroduodenoscopy using magnifying endoscope with narrow band imaging for gastric cancer
Abstract ObjectivesIn Japan, an increase in the number of routine esophagogastroduodenoscopy procedures is expected because several studies have reported that endoscopy screenings have reduced gastric cancer mortality. Magnifying narrow‐band imaging has been reported to be effective for accurate diagnosis of gastric abnormalities such as cancers, adenomas, and intestinal metaplasia. However, the efficacy of this method in routine esophagogastroduodenoscopy has not been clarified. MethodsWe divided 3,763 patients into two groups. The non‐magnification group included 1,842 patients who underwent endoscopy screening using...
Source: Digestive Endoscopy - July 1, 2017 Category: Gastroenterology Authors: Shoichi Yoshimizu, Yorimasa Yamamoto, Yusuke Horiuchi, Masami Omae, Toshiyuki Yoshio, Akiyoshi Ishiyama, Toshiaki Hirasawa, Tomohiro Tsuchida, Junko Fujisaki Tags: Original Article Source Type: research

Submucosal Tumor of the Stomach With Drastic, Short-term Changes in Morphology
Question: A 47-year-old man was referred to our institution for detailed examination of gastric tumor. One year previously, the patient was diagnosed as  having a submucosal tumor in the upper gastric corpus by screening esophagogastroduodenoscopy (Figure A). On admission, laboratory tests were within normal limits and Helicobacter pylori was negative as determined by the stool antigen test and the serological test. Esophagogastroduodenoscopy revealed that the lesion had increased in size with ulceration (Figure B). (Source: Gastroenterology)
Source: Gastroenterology - June 30, 2017 Category: Gastroenterology Authors: Yosuke Toya, Makoto Eizuka, Takayuki Matsumoto Tags: Clinical Challenges and Images in GI Source Type: research

Exam 2: Longer Observation Time Increases Proportion of Neoplasms Detected by Esophagogastroduodenoscopy
(Source: Gastroenterology)
Source: Gastroenterology - June 29, 2017 Category: Gastroenterology Tags: Continuing Medical Education (CME)/MOC Activities Source Type: research

Gastric Lesion in a Patient With Lynch Syndrome
Question: An asymptomatic, 67-year-old woman was referred for esophagogastroduodenoscopy (EGD) and ileocolonoscopy in view of her diagnosis of Lynch syndrome (LS). The EGD revealed generalized erythema of the gastric mucosa and a urease test was positive. While withdrawing the endoscope, the shown lesion, measuring approximately 3  × 5mm (Figure A, white light imaging), was identified at the middle of the gastric body and multiple biopsies were taken (Figure B, stain: hematoxylin and eosin; C, magnification). (Source: Gastroenterology)
Source: Gastroenterology - June 29, 2017 Category: Gastroenterology Authors: Polychronis Pavlidis, Hadil Abu Arqoub, Bu ’Hussain Hayee Tags: Electronic Clinical Challenges and Images in GI Source Type: research

The Utility of Routine Esophagogastroduodenoscopy Prior to Laparoscopic Roux-en-Y Gastric Bypass
The routine use of esophagogastroduodenoscopy (EGD) prior to laparoscopic Roux-en-y gastric bypass (LRYGB) is debatable. Various studies have reported high diagnostic yield of routine EGD prior to LRYGB in order to detect pathologies that could alter surgical management. However, other studies have found that preoperative EGD did not identify significant pathologies that changed clinical management, and therefore, is not indicated in asymptomatic patients. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - June 28, 2017 Category: Surgery Authors: Warren Y.L. Sun, Jerry T. Dang, Noah J. Switzer, Christopher de Gara, Daniel W. Birch, Shahzeer Karmali Source Type: research

Appropriateness of the study of iron deficiency anemia prior to referral for small bowel evaluation at a tertiary center.
Abstract AIM: To evaluate the adequacy of the study of iron deficiency anemia (IDA) in real life practice prior to referral to a gastroenterology department for small bowel evaluation. METHODS: All consecutive patients referred to a gastroenterology department for small bowel investigation due to iron deficiency anemia, between January 2013 and December 2015 were included. Both patients referred from general practitioners or directly from different hospital departments were selected. Relevant clinical information regarding prior anemia workup was retrospectively collected from medical records. An appropriate ...
Source: World Journal of Gastroenterology : WJG - June 28, 2017 Category: Gastroenterology Authors: Rodrigues JP, Pinho R, Silva J, Ponte A, Sousa M, Silva JC, Carvalho J Tags: World J Gastroenterol Source Type: research

The utility of routine esophagogastroduodenoscopy before laparoscopic Roux-en-Y gastric bypass
The routine use of esophagogastroduodenoscopy (EGD) before laparoscopic Roux-en-y gastric bypass (LRYGB) is debatable. Various studies have reported high diagnostic yield of routine EGD before LRYGB to detect pathologies that could alter surgical management. However, other studies have found that preoperative EGD did not identify significant pathologies that changed clinical management; therefore, it is not indicated in asymptomatic patients. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - June 28, 2017 Category: Surgery Authors: Warren Y.L. Sun, Jerry T. Dang, Noah J. Switzer, Christopher de Gara, Daniel W. Birch, Shahzeer Karmali Tags: Original article Source Type: research

Yield of Endoscopy in Pediatric Gastroparesis
Conclusions: Clinically significant endoscopy findings were common in both controls and gastroparetics. As more than one-third of patients had findings on endoscopy, we conclude that upper endoscopy remains an important part of the evaluation process of patients with dyspeptic symptoms and suspected gastroparesis. As gross abnormalities were frequently not present with histologic changes, routine biopsy is required. There was no association between studied symptoms and the presence of gastroparesis. A comprehensive evaluation of children with dyspeptic symptoms requires endoscopy with biopsy and solid-phase gastric emptyin...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Elevated Serum Tissue Transglutaminase Antibodies in Children With Eosinophilic Esophagitis
Conclusions: Serum TTG Ab was elevated in almost one-quarter of our total EoE cohort, and at least 20% of these patients did not have potential CD, suggesting EoE is a heterogeneous disease with differing immune mechanisms activated in some patients. These findings also support routine esophageal biopsy during upper endoscopy in children with elevated TTG Ab. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research

Primary Gastric ALK-negative EBV-negative Anaplastic Large Cell Lymphoma Presenting with Iron Deficiency Anemia
Anaplastic large cell lymphoma (ALCL) is a rare subtype of non-Hodgkin lymphoma (NHL). Primary gastric anaplastic lymphoma kinase (ALK) negative ALCL is extremely rare. Diagnosis of primary gastric ALK-negative ALCL is difficult to establish and prognosis is worse than ALK-positive ALCL. Here, we report a case of an 82-year-old man with a history of cerebrovascular disease presented with weakness and iron deficiency anemia. He denied any abdominal discomforts. The esophagogastroduodenoscopy revealed a large ulcerated, friable mass in the gastric body which encompassed about 80% of entire stomach. Biopsy showed a high grade...
Source: In Vivo - June 24, 2017 Category: Research Authors: ZHANG, W., BURTON, S., WU, S., QIAN, X., RAJEH, M. N., SCHROEDER, K., SHULDBERG, M., MERANDO, A., LAI, J.-P. Tags: Clinical Studies Source Type: research

Esophago-pulmonary fistula manifesting as recurrent pneumonias and migrating mediastinal calcifications.
Authors: Kebbe J, Yendamuri S, Roche C, Harris K, Dhillon SS Abstract A 43-year old man presented with recurrent pneumonias, episodes of hemoptysis and an enlarging right lower lobe mass. A clear diagnosis was not previously established in spite of multiple radiological evaluations and biopsies. Meticulous review of his CT imaging showed that he had subcarinal calcification on his prior CT scans, which had decreased in size and now multiple new small areas of calcifications were seen in the right lower lobe lesion. An esophago-pulmonary fistula due to migration of mediastinal calcifications was suspected which was ...
Source: Monaldi Archives for Chest Disease - June 23, 2017 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

A case of API2-MALT1-positive gastric MALT lymphoma with concomitant diffuse large B-cell lymphoma.
Authors: Fujita A, Tajika M, Tanaka T, Ishihara M, Hirayama Y, Mizuno N, Hara K, Hijioka S, Imaoka H, Yoshida T, Okuno N, Hieda N, Hirayama T, Shibuya H, Kondo H, Suzuki H, Toriyama K, Yatabe Y, Yamao K, Niwa Y Abstract API2-MALT1 translocation-positive gastric marginal zone lymphomas of mucosa-associated lymphoid tissue (MALT) lymphoma is thought to transform to diffuse large B-cell lymphoma (DLBCL) rarely. A 69-year-old man presented with epigastralgia. Esophagogastroduodenoscopy showed multiple ulcerations in the stomach. Endoscopic biopsies revealed MALT lymphoma, with Helicobacter pylori infection. The patient...
Source: Nagoya Journal of Medical Science - June 21, 2017 Category: International Medicine & Public Health Tags: Nagoya J Med Sci Source Type: research

Primary squamous cell carcinoma of the thyroid: case report and systematic review of the literature
Conclusion Reported disease free survival of PSCC of the thyroid was only achieved in patients with complete surgical resection in combination with adjuvant radio- and/or chemotherapy. However long term survival has not been reported in the literature yet. (Source: International Journal of Surgery Case Reports)
Source: International Journal of Surgery Case Reports - June 15, 2017 Category: Surgery Source Type: research

An alternative view on the necessity of EGD before sleeve gastrectomy.
Abstract BACKGROUND: Esophagogastroduodenoscopy (EGD) is particularly recommended for choosing a surgical method to be used with asymptomatic patients and for the assessment of symptomatic patients prior to sleeve gastrectomy. The presence of hiatal hernia, for instance, is a relative contraindication. EGD is used for malignancy scanning as well as surgical planning, but seems inefficient in determining postoperative complications. OBJECTIVE: Our aim was to investigate the effectiveness of the pathological evaluation of endoscopic biopsies obtained with esophagogastroduodenoscopy (EGD) according to Sydney cla...
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - June 15, 2017 Category: Surgery Authors: Peker KD, Sahbaz NA, Seyit H, Kones O, Gumusoglu AY, Alis H Tags: Surg Obes Relat Dis Source Type: research

Endoscopic Sleeve Gastroplasty - A New Tool to Manage Obesity.
Authors: Jain D, Bhandari BS, Arora A, Singhal S Abstract Obesity is a growing pandemic across the world. Dietary restrictions and behavior modifications alone have a limited benefit. Bariatric surgery, despite being the current gold standard, has limited acceptance by patients due to cost and associated morbidity. In our review, we have discussed nine original studies describing endoscopic sleeve gastroplasty (ESG). A total of 172 subjects successfully underwent ESG. Of 65 subjects with follow up data, 95.4% (62/65) had intact gastric sleeve confirmed via esophagogastroduodenoscopy or oral contrast study at the en...
Source: Clinical Endoscopy - June 14, 2017 Category: Gastroenterology Tags: Clin Endosc Source Type: research

An Alternative View on the Necessity of EGD Prior to Sleeve Gastrectomy
Our aim was to investigate the effectiveness of the pathological evaluation of endoscopic biopsies obtained with esophagogastroduodenoscopy (EGD) according to Sydney classification prior to sleeve gastrectomy in identifying the risk of staple line leak, independently of clinical diagnosis. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - June 14, 2017 Category: Surgery Authors: Kivanc Derya Peker, Nuri Alper Sahbaz, Hakan Seyit, Osman Kones, Alpen Yahya Gumusoglu, Halil Alis Tags: Paired papers Source Type: research

Application of novel magnified single balloon enteroscopy for a patient with Cronkhite-Canada syndrome.
We present a case of Cronkhite-Canada syndrome (CCS) in which the entire intestine was observed using a prototype of magnifying single-balloon enteroscope (SIF Y-0007, Olympus). CCS is a rare, non-familial gastrointestinal polyposis with ectodermal abnormalities. To our knowledge, this is the first report showing magnified intestinal lesions of CCS. A 73-year-old female visited our hospital with complaints of diarrhea and dysgeusia. The blood test showed mild anemia and hypoalbuminemia. The esophagogastroduodenoscopy and colonoscopy revealed diffuse and reddened sessile to semi-pedunculated polyps, resulting in the diagnos...
Source: World Journal of Gastroenterology : WJG - June 14, 2017 Category: Gastroenterology Authors: Murata M, Bamba S, Takahashi K, Imaeda H, Nishida A, Inatomi O, Tsujikawa T, Kushima R, Sugimoto M, Andoh A Tags: World J Gastroenterol Source Type: research

An alternative view on the necessity of EGD before sleeve gastrectomy
Our aim was to investigate the effectiveness of the pathologic evaluation of endoscopic biopsies obtained with esophagogastroduodenoscopy according to Sydney classification before sleeve gastrectomy in identifying the risk of staple line leak, independently of clinical diagnosis. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - June 14, 2017 Category: Surgery Authors: Kivanc Derya Peker, Nuri Alper Sahbaz, Hakan Seyit, Osman Kones, Alpen Yahya Gumusoglu, Halil Alis Tags: Original article Source Type: research

The armadillo factor: lepromatous leprosy
Travelers, whether they are temporary visitors or immigrants, can bring along an infection that ’s endemic to the home turf. A 31-year-old Hispanic man, currently a prison inmate, presented with a 6-month history of fatigue, night sweats, weight loss, and malaise. At a prior facility, he was diagnosed with anemia and underwent esophagogastroduodenoscopy and colonoscopy. Both were negative fo r gastrointestinal bleeding. The patient also complained of chronic nasal discharge and had seen an otolaryngologist, who identified nasal septal ulceration and scarring. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - June 13, 2017 Category: General Medicine Authors: Laura C. Cleary, Smitha Suraj, David Haburchak, Jake E. Turrentine Tags: Images in Dermatology Source Type: research

Noncardiac chest pain: diagnosis and management
Purpose of review: Noncardiac chest pain (NCCP) has been defined as recurrent chest pain that is indistinguishable from ischemic heart pain after excluding a cardiac cause. NCCP is a common and highly challenging clinical problem in Gastrointestinal practice that requires targeted diagnostic assessment to identify the underlying cause of the symptoms. Treatment is tailored according to the cause of NCCP: gastroesophageal reflux disease (GERD), esophageal dysmotility or functional chest pain. The purpose of this review is to discuss the current diagnosis and treatment of NCCP. Recent findings: Utilization of new diagnostic...
Source: Current Opinion in Gastroenterology - June 9, 2017 Category: Gastroenterology Tags: ESOPHAGUS: Edited by Stuart J. Spechler Source Type: research

Endoscopic Bubble Trouble: Hyperbaric Oxygen Therapy for Cerebral Gas Embolism During Upper Endoscopy
We describe 3 cases of gas embolism which were associated with endoscopic procedures (esophagogastroduodenoscopy and endoscopic retrograde cholangiopancreatography). We treated these at our hyperbaric medicine center with 3 different outcomes: complete resolution, death, and disability. We review the literature regarding this unusual complication of endoscopy and discuss the need for prompt identification and referral for hyperbaric oxygen therapy. Additional adjunctive therapies are also discussed. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - June 8, 2017 Category: Gastroenterology Tags: ONLINE ARTICLES: Case Report Source Type: research

An Unusual Cause of Recurrent Vomiting
Question: A 28-year-old man was admitted for postprandial epigastric pain, and chronic vomiting for 6 months, associated with a 6-kg weight loss. He had no relevant medical or family history. Physical examination and laboratory workup were normal. An anechoic lesion located in the second part of the duodenum wall was revealed on abdominal ultrasound imaging, and a submucosal mass was diagnosed in the same region, using an upper endoscopy technique. Furthermore, endoscopic ultrasound imaging and magnetic resonance imaging with dynamic sequences showed a 25  × 26-mm cystic duodenal lesion. (Source: Gastroenterology)
Source: Gastroenterology - June 5, 2017 Category: Gastroenterology Authors: Romain Leenhardt, Xavier Dray, Ulriikka Chaput Tags: Electronic Clinical Challenges and Images in GI Source Type: research

Efficacy and safety of midazolam and ketamine in paediatric upper endoscopy
Conclusion The results of our study showed that the use of IV midazolam and ketamine during upper endoscopy in children was safe and effective. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - June 2, 2017 Category: Gastroenterology Source Type: research

New Directions in Barrett ’s Esophagus
I am so pleased to introduce this issue of Gastrointestinal Endoscopy Clinics of North America, “New Directions in Barrett’s Esophagus.” In terms of the morbidity and mortality associated with it, as well as the resources expended on it, Barrett’s esophagus (BE) and esophageal adenocarcinoma rank high in gastrointestinal (GI) maladies. Indeed, the question of how to manage the patient with chronic heartburn is probably second only to colorectal cancer screening as a public health concern in GI, and indications related to gastroesophageal reflux disease are routinely at or near the top the list for u...
Source: Gastrointestinal Endoscopy Clinics of North America - June 1, 2017 Category: Gastroenterology Authors: Nicholas J. Shaheen Tags: Preface Source Type: research

Diagnosis and management of head and neck cancers in a high-incidence area in France: A population-based study
Abstract: Head and neck cancers have a very poor prognosis and are common in France. They are subject to various recommendations for early detection and management, but there is no detailed data in the French general population to fuel the public health debate on it. A high-resolution population-based study about cancer management was conducted, using cancers registries in the north-west of France, on 1729 tumors diagnosed between 2008 and 2010. The tumors were diagnosed late (70.3% stage III–IV), mainly after the onset of symptoms (93.2%). After adjustment, advanced stages were more frequent in patients with hypop...
Source: Medicine - June 1, 2017 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Electromagnetic-guided placement of nasoduodenal feeding tubes versus endoscopic placement: a randomized, multicenter trial
Electromagnetic-guided placement (EMP) of a nasoduodenal feeding tube by trained nurses is an attractive alternative to esophagogastroduodenoscopy guided placement (EGDP). We aimed to compare EMP and EGDP in outpatients, ward patients, and critically ill patients with normal upper GI anatomy. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - June 1, 2017 Category: Gastroenterology Authors: Wouter F.W. Kappelle, Daisy Walter, Paul Stadhouders, Hendrik J.A. Jebbink, Frank P. Vleggaar, Peter van der Schaar, Jan Willem Kappelle, Ingeborg van der Tweel, Medard F.M. Van den Broek, Frank J. Wessels, Peter D. Siersema, Jan F. Monkelbaan Source Type: research

Salivary epidermal growth factor concentrations in patients with Sj ögren syndrome and laryngopharyngeal reflux.
The objective of this prospective cohort study was to compare salivary epidermal growth factor (EGF) concentrations of patients with Sjögren syndrome with and without LPR and gastroesophageal reflux disease (GERD) with normal controls. LPR was diagnosed with positive scores on the Reflux Symptom Index and Reflux and Reflux Finding Score, corroborated by esophagogastroduodenoscopy and/or 24-hour pH-metry. Salivary EGF concentrations of both unstimulated and mechanically stimulated saliva were established using enzyme-linked immunosorbent assay, and the significance level was set at 95%. Twenty-one patients and 19 contr...
Source: Ear, Nose and Throat Journal - June 1, 2017 Category: ENT & OMF Authors: Eckley CA, Dos Anjos Corvo MA, Sardinha LR, Liquidato B, Rizzo LV Tags: Ear Nose Throat J Source Type: research

Importance of Second-look Endoscopy on an Empty Stomach for Finding Gastric Bezoars in Patients with Gastric Ulcers.
In conclusion, gastric bezoars may not be discovered during the initial esophagogastroduodenoscopy and CT scan. In cases with debris in the stomach, second-look endoscopy is essential to detect bezoars. PMID: 28655944 [PubMed - in process] (Source: Acta Med Okayama)
Source: Acta Med Okayama - June 1, 2017 Category: Universities & Medical Training Authors: Iwamuro M, Tanaka S, Moritou Y, Inaba T, Higashi R, Kusumoto C, Yunoki N, Ishikawa S, Okamoto Y, Kawai Y, Kitada KI, Takenaka R, Toyokawa T, Okada H Tags: Acta Med Okayama Source Type: research

Efficacy and Safety of the Triple Therapy Containing Ilaprazole, Levofloxacin, and Amoxicillin as First-Line Treatment in Helicobacter pylori Infections.
Conclusions. A 10-day triple therapy containing ilaprazole, levofloxacin, and amoxicillin is a safe alternative first-line eradication treatment for H. pylori. PMID: 28539935 [PubMed - in process] (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - May 27, 2017 Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research

Central Obesity as a Risk Factor for Non-Erosive Reflux Disease.
Abstract PURPOSE: Although central obesity is a risk factor for erosive esophagitis, information regarding the association between central obesity and non-erosive reflux disease (NERD) is still scarce. The purpose of this study was to investigate the risk factors for NERD by comparing NERD patients and healthy controls. MATERIALS AND METHODS: Comprehensive clinical data from 378 patients who underwent esophagogastroduodenoscopy from December 2012 to May 2013 and had no visible esophageal mucosal breakage were analyzed. The Korean version of GerdQ questionnaire was used to diagnose NERD. The association betwee...
Source: Yonsei Medical Journal - May 27, 2017 Category: Universities & Medical Training Authors: Kim KJ, Lee BS Tags: Yonsei Med J Source Type: research

Protein-Losing Enteropathy as a Complication of the Ketogenic Diet.
We present a 16-month-old Down syndrome baby with protein-losing enteropathy during the ketogenic diet as a treatment for West syndrome. He suffered from diarrhea, general edema and hypoalbuminemia which were not controlled by conservative care for over 1 month. Esophagogastroduodenoscopy and stool alpha-1 antitrypsin indicated protein-losing enteropathy. Related symptoms were relieved after cessation of the ketogenic diet. Unexplained hypoalbuminemia combined with edema and diarrhea during ketogenic suggests the possibility of protein-losing enteropathy, and proper evaluation is recommended in order to expeditiously detec...
Source: Yonsei Medical Journal - May 27, 2017 Category: Universities & Medical Training Authors: Ahn WK, Park S, Kim HD Tags: Yonsei Med J Source Type: research

Day-care unit for rigid panendoscopy of the upper aerodigestive tract: A study of 436 procedures
Conclusion Day-care management is appropriate for UADT panendoscopy in selected patients. The reasons for the high rate of patient refusal should be studied. (Source: European Annals of Otorhinolaryngology, Head and Neck Diseases)
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - May 26, 2017 Category: ENT & OMF Source Type: research

Three stage esophagectomy combined with abdominal aortic aneurysm repair: first case in the literature
The purpose of this report is to describe the synchronous surgical treatment of an abdominal aortic aneurysm (AAA) with concomitant esophageal cancer (EC) with a three-stage esophagectomy, a real management challenge especially in establishing the therapeutic priorities and the ideal treatment approach.A 65-year old male was referred for treatment in our hospital with the diagnosis of AAA. He complained of general fatigue, weight loss and intermittent dysphagia. Contrast-enhanced CT and upper endoscopy showed the AAA and a large gastroesophageal junction (GEJ) tumor respectively. (Source: Annals of Vascular Surgery)
Source: Annals of Vascular Surgery - May 23, 2017 Category: Surgery Authors: Chris Klonaris, Dimitrios Schizas, Georgios Karaolanis, Dimitrios Athanasiadis, Andreas Alexandrou, Theodore Liakakos Source Type: research

Three-Stage Esophagectomy Combined with Abdominal Aortic Aneurysm Repair: First Case in the Literature
The purpose of this report is to describe the synchronous surgical treatment of an abdominal aortic aneurysm (AAA) with concomitant esophageal cancer with a 3-stage esophagectomy, a real management challenge especially in establishing the therapeutic priorities and the ideal treatment approach. A 65-year-old male was referred for treatment in our hospital with the diagnosis of AAA. He complained of general fatigue, weight loss, and intermittent dysphagia. Contrast-enhanced computed tomography and upper endoscopy showed the AAA and a large gastroesophageal junction tumor, respectively. (Source: Annals of Vascular Surgery)
Source: Annals of Vascular Surgery - May 23, 2017 Category: Surgery Authors: Chris Klonaris, Dimitrios Schizas, Georgios Karaolanis, Dimitrios Athanasiadis, Andreas Alexandrou, Theodore Liakakos Tags: Case Report Source Type: research

Polymorphisms of microRNA target genes IL12B, INSR, CCND1 and IL10 in gastric cancer.
Abstract AIM: To evaluate associations between miRNA target genes IL12B, INSR, CCND1 and IL10 polymorphisms and gastric cancer (GC) in European population. METHODS: Gene polymorphisms were analyzed in 508 controls and 474 GC patients from 3 tertiary centers in Germany, Lithuania and Latvia. Controls were patients from the out-patient departments, who were referred for upper endoscopy because of dyspeptic symptoms and had no history of previous malignancy. Gastric cancer (GC) patients had histopathological verification of gastric adenocarcinoma. Genomic DNA was extracted using salting out method from periphera...
Source: World Journal of Gastroenterology : WJG - May 21, 2017 Category: Gastroenterology Authors: Petkevicius V, Salteniene V, Juzenas S, Wex T, Link A, Leja M, Steponaitiene R, Skieceviciene J, Kupcinskas L, Jonaitis L, Kiudelis G, Malfertheiner P, Kupcinskas J Tags: World J Gastroenterol Source Type: research

Gastric Perforation Caused by an Intragastric Balloon: Endoscopic Findings.
Authors: Yoo IK, Chun HJ, Jeen YT Abstract Intragastric balloon (IGB) insertion has been most frequently used in the West as an effective endoscopic treatment for morbid obesity, in practice. Recently, there is a growing number of cases requiring IGB deployment for obesity treatment in Korea. One of the reported complications of IGB use is gastric perforation. A 47-year-old woman was admitted to the hospital with mild symptoms, 7 weeks after having an IGB placed. Esophagogastroduodenoscopy was performed and gastric ulcer perforation was observed in the ulcer base, where food particles were impacted. Laparoscopic pr...
Source: Clinical Endoscopy - May 19, 2017 Category: Gastroenterology Tags: Clin Endosc Source Type: research

Bleeding Risk Related to Upper Gastrointestinal Endoscopic Biopsy in Patients Receiving Antithrombotic Therapy: A Multicenter Prospective Observational Study
Conclusions We found no significant increase in upper-GI bleeding risk following an EGD biopsy in patients taking antithrombotic agents, suggesting its safety without the need for antithrombotic treatment interruption. (Source: Current Therapeutic Research)
Source: Current Therapeutic Research - May 15, 2017 Category: Drugs & Pharmacology Source Type: research