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Primary Gastric EBV-positive Diffuse Large B Cell Lymphoma (DLBCL) of the Elderly with Plasmablastic Differentiation
Epstein–Barr virus (EBV)-positive diffuse large B cell lymphoma (DLBCL) of the elderly is a rare subtype of B-cell neoplasms. Primary gastric EBV-positive DLBCL of the elderly with partial plasmablastic phenotype is extremely rare. Differentiation of EBV-positive DLBCL of the elderly with partial plasmablastic phenotype from true plasmablastic lymphoma (PBL) is difficult and very important from the therapeutic and prognostic point of view. Here we report a case of a 59-year-old man with upper gastrointestinal bleeding. The esophagogastroduodenoscopy revealed a 2-cm malignant-appearing non-bleeding gastric ulcer in th...
Source: In Vivo - February 23, 2018 Category: Research Authors: HU, M., TREVINO, J., YANG, L., CAO, D., LIU, X., LAI, J. Tags: Clinical Studies Source Type: research

An unusual presentation of adult T-cell leukemia/lymphoma.
We reported this case to raise awareness and demonstrate the therapeutic challenges of this rare disease. A 49-year-old Japanese female presented with skin papules on both forearms, painful mouth ulcers and multiple neck swellings since early February 2017. Initial clinical examination and laboratory investigations were misleading and her condition was diagnosed as candidiasis. Because of un-improvement of the case, a screening upper endoscopy was requested 2 months later and revealed characteristic oropharyngeal ulcers which were biopsied, and its pathologic examination confirmed smouldering type ATL. This case report sho...
Source: Ecancermedicalscience - February 20, 2018 Category: Cancer & Oncology Tags: Ecancermedicalscience Source Type: research

Management of Esophageal Food Impaction Varies Among Gastroenterologists and Affects Identification of Eosinophilic Esophagitis
ConclusionsEFI management varies substantially among GIs associated with three major gastroenterology societies in USA. Based on their practice patterns, the GIs in USA are likely to miss numerous EoE patients presenting to ER with EFI. Our findings highlight the need for developing and disseminating evidence-based EFI management practice guidelines. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - February 20, 2018 Category: Gastroenterology Source Type: research

Serological biomarker testing helps avoiding unnecessary endoscopies in obese patients before bariatric surgery
ConclusionsThe normal biomarker profile is an excellent surrogate for healthy stomach, implicating that pre-operative EGDS could have been avoided in 31% of our asymptomatic bariatric surgery patients who had the normal biomarker profile. (Source: BMC Obesity)
Source: BMC Obesity - February 20, 2018 Category: Eating Disorders & Weight Management Source Type: research

Unexpected cause for duodenal obstruction: Brunner's gland hyperplasia.
We report an unusual case of large Brunner's gland hyperplasia in 72-years old man, admitted to hospital for epigastric pain, recurrent vomiting and significantly weight loss. Upper endoscopy showed an obstructive submucosis tumour of the bulb. Abdominal computed tomography scan revealed a circumferential thickening and stenosing mass of the first part of the duodenum leading to severe obstruction. Though pre-operative biopsies were negative, imaging studies and endoscopy were strongly suggestive of malignancy and the patient underwent duodenocephalopancreatectomy. Brunner's gland hyperplasia may have unusual presentation,...
Source: Pathologica - February 18, 2018 Category: Pathology Tags: Pathologica Source Type: research

Non ‐alcoholic fatty liver disease and the development of reflux esophagitis: A cohort study
Abstract Background and AimNon‐alcoholic fatty liver disease (NAFLD), a hepatic manifestation of the metabolic syndrome, is associated with gastroesophageal reflux disease in cross‐sectional studies, but a prospective association has not been evaluated. The current study aimed to determine whether NAFLD increases the risk of incident reflux esophagitis in a large cohort study. MethodsWe conducted a cohort study of 34 063 men and women without reflux esophagitis or other upper gastrointestinal disease at baseline who underwent health checkup examinations between January 2003 and December 2013. Fatty liver was diagn...
Source: Journal of Gastroenterology and Hepatology - February 15, 2018 Category: Gastroenterology Authors: Yang Won Min, Youngha Kim, Geum ‐Youn Gwak, Seonhye Gu, Danbee Kang, Soo Jin Cho, Eliseo Guallar, Juhee Cho, Dong Hyun Sinn Tags: Gastroenterology Source Type: research

A Case of Helicobacter pylori-negative Advanced Gastric Cancer with Massive Eosinophilia.
Authors: Takagi A, Ozawa H, Oki M, Yanagi H, Nabeshima K, Nakamura N Abstract The incidence of Helicobacter pylori-negative gastric cancer is very low. A 60-year-old man was referred to Tokai University Hospital from a local clinic because of eosinophilia. The laboratory data revealed prominent eosinophilia, with a white blood cell count of 7,900/μl and increased eosinophil granulocyte level of 1,659/μl. After an examination for secondary eosinophilia, esophagogastroduodenoscopy showed an enlarged gastric fold in the corpus, suggesting type 4 gastric cancer. Repeated EGD and a re-biopsy demonstrated poorly di...
Source: Internal Medicine - February 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

First-line treatment of Helicobacter pylori in Lebanon: Comparison of bismuth-containing quadruple therapy versus 14-days sequential therapy
In conclusion, we determined H. pylori and gastritis prevalence among Lebanese PU-patients and showed that 14-days sequential therapy is more efficient than bismuth-containing quadruple therapy in terms of H. Pylori-eradication. (Source: Microbial Pathogenesis)
Source: Microbial Pathogenesis - February 13, 2018 Category: Infectious Diseases Source Type: research

Lack of correlation between gastro-esophageal reflux disease symptoms and esophageal lesions after sleeve gastrectomy
The post-operative development or worsening of gastro-esophageal reflux disease (GERD) represents the major drawback of laparoscopic Sleeve Gastrectomy (SG). GERD diagnosis is often based only on symptoms and proton pump inhibitors (PPI) intake, while objective tests like esophagogastroduodenoscopy (EGD) and pH measurements are performed less frequently. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - February 13, 2018 Category: Surgery Authors: E. Soricelli, G. Casella, G. Baglio, R. Maselli, I. Ernesti, A. Genco Source Type: research

Adherence to Surveillance Guidelines in Nondysplastic Barrett’s Esophagus
Conclusions: In a single-center VA cohort, sEGD of NDBE was mostly nonadherent to guidelines. Adherent cases were older at baseline with a trend toward more LSBE. A larger study is needed to identify medical and social factors associated with adherence or nonadherence to surveillance. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - February 8, 2018 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Laparoscopic management of large hiatal hernia: mesh method with the use of ProGrip mesh versus standard crural repair
This study was performed on 98 gastroesophageal reflux disease patients who underwent Nissen fundoplication with mesh-augmented crura repair and fundoplication with standard crura repair. We used non-absorbable laparoscopic self-fixating mesh by ProGrip ™. All patients were separated into the mesh group (n = 50) and non-mesh group (n = 48). The groups were evaluated according to the following criteria: dysphagia, patients’ symptomatic outcome judgment according to The Gastroesophageal Reflux Disease-Health Related Quality of Life (GERD-HRQL) questionnaire and patients’ satisfac...
Source: Surgical Endoscopy - February 8, 2018 Category: Surgery Source Type: research

Risk of Oral and Upper Gastrointestinal Cancers in Persons With Positive Results From a Fecal Immunochemical Test in a Colorectal Cancer Screening Program
European guidelines recommend screening for colorectal cancer (CRC) using the fecal immunochemical test (FIT), with follow-up colonoscopies for individuals with positive test results. However, more than half of participants with positive results from the FIT are not found to have advanced neoplasia in the colonoscopy examination. Fecal occult blood might also come from the upper gastrointestinal (GI) tract, so perhaps we should consider esophagogastroduodenoscopy (EGD), to detect upper GI cancers. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 7, 2018 Category: Gastroenterology Authors: Manon van der Vlugt, Esm ée J. Grobbee, Patrick M. Bossuyt, Amanda C.R.K. Bos, Ernst J. Kuipers, Iris Lansdorp-Vogelaar, Manon C.W. Spaander, Evelien Dekker Source Type: research

Complications and outcomes of routine endoscopy in the very elderly
Endosc Int Open 2018; 06: E224-E229 DOI: 10.1055/s-0043-120569 Background and study aims In Japan, the elderly population has been increasing annually. The number of elderly patients for whom esophagogastroduodenoscopy (EGD) and colonoscopy (CS) is indicated also has been rising. The aim of this study was to evaluate the safety and efficacy of routine endoscopy in a cohort of octogenarians aged 85 years and older – defined by the World Health Organization as the very elderly. Patients and methods A total of 5,586 patients underwent EGDs, and 2,484 patients underwent CSs performed at the Keio Universit...
Source: Endoscopy International Open - February 7, 2018 Category: Gastroenterology Authors: Miyanaga, Ryoichi Hosoe, Naoki Naganuma, Makoto Hirata, Kenro Fukuhara, Seiichiro Nakazato, Yoshihiro Ojiro, Keisuke Iwasaki, Eisuke Yahagi, Naohisa Ogata, Haruhiko Kanai, Takanori Tags: Original article Source Type: research

Effect of the midazolam added with propofol ‐based sedation in esophagogastroduodenoscopy: A randomized trial
ConclusionAdding midazolam to propofol did not reduced the safety and efficacy, and sedation using propofol alone could be suitable for sedation during diagnostic EGD. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - February 6, 2018 Category: Gastroenterology Authors: Eun Hye Kim, Jun Chul Park, Sung Kwan Shin, Yong Chan Lee, Sang Kil Lee Tags: Endoscopy Source Type: research

Clinical significance of small ‐bowel villous edema in patients with liver cirrhosis: A capsule endoscopy study
ConclusionsClinical factors related to portal hypertension were significantly correlated with VE. In particular PVT was correlated with the appearance and exacerbation of VE. Periodic capsule endoscopy in LC patients may lead to early detection of portal hypertension and PVT. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - February 6, 2018 Category: Gastroenterology Authors: Ichiro Otani, Shiro Oka, Shinji Tanaka, Akiyoshi Tsuboi, Sayoko Kunihara, Yuko Nagaoki, Hiroshi Aikata, Kazuaki Chayama Tags: Gastroenterology Source Type: research

Is Preoperative Gastroscopy Necessary prior to Sleeve Gastrectomy and Roux-en-Y gastric bypass?
Consensus on the necessity of esophagogastroduodenoscopy (EGD) prior to bariatric surgery is lacking. Recommendations and practices vary by country and unit. Several reports have expressed concerns on gastroesophageal reflux disease (GERD) and its consequences after sleeve gastrectomy (SG) and the risk of leaving a premalignant lesion in the excluded stomach after Roux-en-Y gastric bypass (RYGB). (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - February 5, 2018 Category: Surgery Authors: Tuure Saarinen, Ulla Kettunen, Kirsi H. Pietil äinen, Anne Juuti Source Type: research

Double Major Duodenal Papillae: A Rare Congenital Anomaly of  Hepatic and Pancreatic Drainage System
A 36-year-old man who presented with intractable nausea and vomiting had double major duodenal papillae, which were noticed during esophagogastroduodenoscopy (Figure A). This is an incidental but fascinating finding. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 5, 2018 Category: Gastroenterology Authors: Jiten P. Kothadia, Vyshnavi Kone, Abbas Raza Tags: Electronic Image of the Month Source Type: research

Is preoperative gastroscopy necessary before sleeve gastrectomy and Roux-en-Y gastric bypass?
Consensus on the necessity of esophagogastroduodenoscopy (EGD) before bariatric surgery is lacking. Recommendations and practices vary by country and unit. Several reports have expressed concerns on gastroesophageal reflux disease (GERD) and its consequences after sleeve gastrectomy (SG) and the risk of leaving a premalignant lesion in the excluded stomach after Roux-en-Y gastric bypass (RYGB). (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - February 5, 2018 Category: Surgery Authors: Tuure Saarinen, Ulla Kettunen, Kirsi H. Pietil äinen, Anne Juuti Tags: Original article Source Type: research

“Diagnostic Utility of Endoscopy and Biopsy in Suspected Acute Gastrointestinal Graft Versus Host Disease (GI-GVHD) Following Haematopoietic Progenitor Cell Transplantation (HPCT).”
• Routine performance of upper endoscopy does not significantly increase diagnostic yield for GI-GVHD.• Diarrhoea and advanced age are the only predictors for identifying histological GVHD in patients suspected of having GI-GVHD.• Of the patients who are ultimately treated for GI-GVHD, only 74 % have GVHD confirmed on biopsy, thus highlighting a need for improved diagnostic techniques. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - February 3, 2018 Category: Hematology Authors: Ashleigh Scott, Siok-Keen Tey, Jason Butler, Glen A. Kennedy Source Type: research

Role of narrow ‐band imaging in detection of head and neck unknown primary squamous cell carcinoma
ConclusionsIn the present study, office‐based NBI increased the detection rate of head and neck SCCUPs by 34.5% and should be strongly recommended as an adjunctive tool in their diagnostic workup. Level of Evidence4. Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - February 2, 2018 Category: ENT & OMF Authors: Marta Filauro, Alberto Paderno, Pietro Perotti, Filippo Marchi, Sabrina Garofolo, Giorgio Peretti, Cesare Piazza Tags: Head and Neck Source Type: research

Diagnostic yield of esophagogastroduodenoscopy in children with chronic abdominal pain.
Conclusions: We determined a high diagnostic yield of EGD in children with CAP. Although the diagnostic yield of EGD in the assessment of CAP was found to be higher in the presence of alarm symptoms, a significant number of children without alarm symptoms were also found to have gastrointestinal system pathology diagnosed by EGD. PMID: 29379535 [PubMed] (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 1, 2018 Category: General Medicine Tags: Arch Med Sci Source Type: research

A technique for teaching and photo ‐documentation of direct endoscopic rigid oesophagoscopy
This article is protected by copyright. All rights reserved. (Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - February 1, 2018 Category: ENT & OMF Authors: Elinor Warner, Rogan Corbridge Tags: Technical Note Source Type: research

Image-enhanced endoscopy is specific for the diagnosis of non-erosive gastroesophageal reflux disease.
CONCLUSIONS: Image-enhanced endoscopic findings of vascularity and micro-erosions were very specific for non-erosive GERD. Image-enhanced endoscopy may be useful in real-time diagnosis of non-erosive GERD when patients undergo upper endoscopy for heartburn. The relative utility of image-enhanced endoscopy vs. pH-impedance monitoring, based on efficacy, cost and patient acceptance, requires additional study. PMID: 29368532 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 26, 2018 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Very low rates of Helicobacter pylori infection in organ transplant recipients presenting with peptic ulcer disease.
CONCLUSION: Organ transplant recipients with PUD have lower rates of Helicobacter pylori positivity compared to the general population. PMID: 29364094 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 26, 2018 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

A rare mass in the duodenal bulb: Brunner's glands cystadenoma.
Authors: Guo T, Tan Y, Liu D Abstract A 56-year-old man referred to our department for treatment of a mass in the duodenal bulb. Esophagogastroduodenoscopy(EGD) showed a large spherical mass extending from the pyloric canal to the anterior wall of the duodenal bulb.The patient received endoscopic submucosal dissection uneventfully.Histology demonstrated Brunner's glands csytadenoma finally. PMID: 29368943 [PubMed - as supplied by publisher] (Source: Revista Espanola de Enfermedades Digestivas)
Source: Revista Espanola de Enfermedades Digestivas - January 26, 2018 Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research

Endoscopy Examination Time: Longer Is Really Better?
I read with interest the article by Park et  al1 regarding the observation time of esophagogastroduodenoscopy (EGD) examination. In this retrospective study, the authors showed that slow endoscopists could detect neoplasms in 0.28% of patients as compared with only 0.20% of patients detected by fast endoscopists. They, thus, suggested that e xamination time is a useful indicator of quality for EGD. Although interesting, a few points need further clarification. (Source: Gastroenterology)
Source: Gastroenterology - January 19, 2018 Category: Gastroenterology Authors: Gin-Ho Lo Tags: Correspondence Source Type: research

Helicobacter pylori infection and occurrence of celiac disease in subjects HLA ‐DQ2/DQ8 positive: A prospective study
ConclusionOur study did not reveal any significant relationship between H. pylori and CD risk, even taking into account other confounders. More importantly, our findings do not support a “protective” role of H. pylori infection against CD, as previously reported. Therefore, there are no reasons to avoid eradication of H. pylori also in subject genetically susceptible for CD. (Source: Helicobacter)
Source: Helicobacter - January 18, 2018 Category: Gastroenterology Authors: Maria P. Dore, Roberta Salis, Maria F. Loria, Vincenzo Villanacci, Gabrio Bassotti, Giovanni M. Pes Tags: ORIGINAL ARTICLE Source Type: research

Short article: The endoscopic and histologic findings of infants who have experienced brief resolved unexplained events
Conclusion Rectosigmoid LNH and eosinophilia, which are associated with milk soy protein intolerance (MSPI), were the most common findings on endoscopic evaluation. Although there is no proof of causation between MSPI and BRUE, MSPI should be considered in the differential diagnosis for higher risk BRUE. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 17, 2018 Category: Gastroenterology Tags: Original Articles: Endoscopy Source Type: research

Treatment of gastrointestinal bleeding with idarucizumab in a patient receiving dabigatran.
CONCLUSION: A patient who had recently undergone PCI and DES placement and was receiving aspirin, clopidogrel, and dabigatran for atrial fibrillation was successfully treated for acute GI bleeding with idarucizumab without the use of a hemostatic agent. PMID: 29343478 [PubMed - as supplied by publisher] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - January 17, 2018 Category: Drugs & Pharmacology Authors: Mourafetis J, Doctor N, Leung S Tags: Am J Health Syst Pharm Source Type: research

Glyphosate ingestion causing multiple organ failure: a near-fatal case report.
Abstract A 55 years old man self-presented to our Emergency Department (ED) reporting an attempted suicide by cutting the left forearm veins and ingesting approximately 200 mL of an herbicide (Myrtos®, containing 36% of glyphosate as isopropylamine salt). Laboratory tests showed metabolic acidosis. Hydration with normal saline and alkalinization with sodium bicarbonate was started according to suggestion of the poison control center, since an antidote was unavailable. Cardiorespiratory condition gradually worsened, so that non-invasive positive pressure ventilation (NIPPV) was applied and infusion of fluids wa...
Source: Acta Bio-Medica : Atenei Parmensis - January 16, 2018 Category: General Medicine Authors: Picetti E, Generali M, Mensi F, Neri G, Damia R, Lippi G, Cervellin G Tags: Acta Biomed Source Type: research

Laparoscopic gastric bypass with remnant gastrectomy in a super-super obese patient with gastric metaplasia: a surgical hazard?
We present the case of a 55-year-old super-super obese man with a family history of GC and antral gastritis with extensive intestinal metaplasia at preoperative upper endoscopy, who underwent laparoscopic RYGBP with remnant gastrectomy. PMID: 29350665 [PubMed - in process] (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - January 16, 2018 Category: General Medicine Authors: Tartamella F, Petracca G, Romboli A, Marchesi F Tags: Acta Biomed Source Type: research

Emergent single-balloon enteroscopy for overt bleeding of small intestinal vascular malformation.
Abstract A 28-year-old man presented with anemia symptoms and intermittent tarry stool passage for three days. No stigmata of hemorrhage were identified using esophagogastroduodenoscopy, ileocolonoscopy, and contrast-enhanced computed tomography. He then developed massive tarry stool passage with profound hypovolemic shock and hypoxic respiratory failure. Emergent angiography revealed active bleeder, probably from the jejunal branches of the superior mesenteric artery, but embolization was not performed due to possible subsequent extensive bowel ischemia. His airway was secured via endotracheal intubation with ven...
Source: World Journal of Gastroenterology : WJG - January 7, 2018 Category: Gastroenterology Authors: Chung CS, Chen KC, Chou YH, Chen KH Tags: World J Gastroenterol Source Type: research

Should asymptomatic young men with iron deficiency anemia necessarily undergo endoscopy?
Abstract Background/Aims: There has been no evidence for the necessity of endoscopy in asymptomatic young men with iron deficiency anemia (IDA). To determine whether endoscopy should be recommended in asymptomatic young men with IDA, we compared the prevalence of gastrointestinal (GI) lesions between young men (
Source: The Korean Journal of Internal Medicine - January 4, 2018 Category: Internal Medicine Authors: Kim NH, Park JH, Park DI, Sohn CI, Choi K, Jung YS Tags: Korean J Intern Med Source Type: research

Familial Mediterranean fever mimicking Crohn disease: A case report
We report a rare case of FMF with gastrointestinal lesions mimicking Crohn disease.Patient concerns:A 21-year-old Japanese man was referred to our institution, complaining of refractory diarrhea and weight loss of 14 kg during the past two years. He had presented with recurrent fever, abdominal pain, anal fistula and stomatitis. His father and one of his brothers had ulcerative colitis. Colonoscopy revealed longitudinal ulcers in the terminal ileum and aphthous erosions in the colorectum. Esophagogastroduodenoscopy revealed multiple linear erosions in the gastric corpus and circular erosions in the duodenal second portio...
Source: Medicine - January 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Tongue diagnosis indices for upper gastrointestinal disorders: Protocol for a cross-sectional, case-controlled observational study
AbstractBackground:Upper gastrointestinal disorders are common in clinical practice, for example, gastritis, peptic ulcer disease, and gastroesophageal reflux disease. Panendoscopy or upper gastrointestinal endoscopy is viewed as the primary tool for examining the upper gastrointestinal mucosa, and permitting biopsy and endoscopic therapy. Although panendoscopy is considered to be a safe procedure with minimal complications, there are still some adverse effects, and patients are often anxious about undergoing invasive procedures. Traditional Chinese medicine tongue diagnosis plays an important role in differentiation of sy...
Source: Medicine - January 1, 2018 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research

Retrograde gastroesophageal intussusception after peroral endoscopic myotomy in a patient with achalasia cardia: A case report
AbstractRationale:Retrograde gastroesophageal intussusception (RGEI) is a relatively rare gastrointestinal (GI) disorder in which a portion of the stomach wall invaginates into the esophagus. More recently, peroral endoscopic myotomy (POEM) has emerged as an endoscopic alternative to surgical myotomy for achalasia, and, to the best of our knowledge, our case is the first RGEI after POEM to be reported.Patient concerns:A 22-year-old male was presented with a history of vomiting, intractable retching and hematemesis for 3 days. He had a history of achalasia and underwent POEM 3 years ago caused by symptoms of severe dysphagi...
Source: Medicine - January 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Tongue diagnosis indices for upper gastrointestinal disorders: Protocol for a cross-sectional, case-controlled observational study
AbstractBackground:Upper gastrointestinal disorders are common in clinical practice, for example, gastritis, peptic ulcer disease, and gastroesophageal reflux disease. Panendoscopy or upper gastrointestinal endoscopy is viewed as the primary tool for examining the upper gastrointestinal mucosa, and permitting biopsy and endoscopic therapy. Although panendoscopy is considered to be a safe procedure with minimal complications, there are still some adverse effects, and patients are often anxious about undergoing invasive procedures. Traditional Chinese medicine tongue diagnosis plays an important role in differentiation of sy...
Source: Medicine - January 1, 2018 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research

Retrograde gastroesophageal intussusception after peroral endoscopic myotomy in a patient with achalasia cardia: A case report
AbstractRationale:Retrograde gastroesophageal intussusception (RGEI) is a relatively rare gastrointestinal (GI) disorder in which a portion of the stomach wall invaginates into the esophagus. More recently, peroral endoscopic myotomy (POEM) has emerged as an endoscopic alternative to surgical myotomy for achalasia, and, to the best of our knowledge, our case is the first RGEI after POEM to be reported.Patient concerns:A 22-year-old male was presented with a history of vomiting, intractable retching and hematemesis for 3 days. He had a history of achalasia and underwent POEM 3 years ago caused by symptoms of severe dysphagi...
Source: Medicine - January 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Transgastric Endoscopic Submucosal Dissection of Esophageal Cancer with Cervical Stricture
This article is protected by copyright. All rights reserved. (Source: Digestive Endoscopy)
Source: Digestive Endoscopy - January 1, 2018 Category: Gastroenterology Authors: Yuichi Shimodate, Yoshio Nagahisa, Motowo Mizuno Tags: Letters, techniques and images Source Type: research

Peptic Ulcers in Fukushima Prefecture Related to the Great East Japan Earthquake, Tsunami and Nuclear Accident.
Conclusion The number of patients with peptic ulcers did not increase immediately following the disaster in Fukushima Prefecture. However, the rate of bleeding patients increased soon after the disaster, especially in the coastal area. PMID: 29269647 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - December 24, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research

Endoscopy services in KwaZulu-Natal Province, South Africa, are insufficient for the burden of disease: Is patient care compromised?
CONCLUSIONS: Endoscopy units in KZN are not adequately equipped to deal with the endoscopy workload and services are plagued by frequent disruptions, which impact negatively on service delivery. There is a need to train more GEs. Patient care is compromised in these public hospitals. PMID: 29262947 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - December 23, 2017 Category: African Health Tags: S Afr Med J Source Type: research

Short article: The endoscopic and histologic findings of infants who have experienced brief resolved unexplained events
Conclusion Rectosigmoid LNH and eosinophilia, which are associated with milk soy protein intolerance (MSPI), were the most common findings on endoscopic evaluation. Although there is no proof of causation between MSPI and BRUE, MSPI should be considered in the differential diagnosis for higher risk BRUE. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 22, 2017 Category: Gastroenterology Tags: Original Articles: Endoscopy Source Type: research

Gastric outlet obstruction in a 12 year old male
Publication date: April 2018 Source:Journal of Pediatric Surgery Case Reports, Volume 31 Author(s): E.S. Bartlett, E.M. Carlisle, G.Z. Mak Pyloric stenosis presenting beyond infancy is uncommon and poorly understood. Here, we present a case of primary acquired gastric outlet obstruction due to pyloric stenosis in a 12-year-old male child. The patient presented after a four-year history of persistent non-bilious, post-prandial emesis and failure to thrive. A Heineke-Mikulicz pyloroplasty was performed. Pyloric biopsy was without diagnostic abnormality. A gastrostomy tube was also placed at the time of pyloroplasty. The pat...
Source: Journal of Pediatric Surgery Case Reports - December 22, 2017 Category: Surgery Source Type: research

Mechanisms of repetitive, retrograde contractions in response to sustained esophageal distension: A study evaluating patients with post-fundoplication dysphagia.
Abstract BACKGROUND: Repetitive, retrograde contractions (RRCs) in response to sustained esophageal distension are a distinct contractility pattern observed with functional luminal imaging probe (FLIP) panometry that are common in type III (spastic) achalasia. RRCs are hypothesized to be indicative of either impaired inhibitory innervation or esophageal outflow obstruction. We aimed to apply FLIP panometry to patients with post-fundoplication dysphagia (a model of esophageal obstruction) to explore mechanisms behind RRCs. METHODS: Adult patients with dysphagia after Nissen fundoplication (n=32) or type III ac...
Source: Am J Physiol Gastroi... - December 21, 2017 Category: Gastroenterology Authors: Carlson DA, Kahrilas PJ, Ritter K, Lin Z, Pandolfino JE Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research

Helicobacter pylori Antimicrobial Susceptibility Testing-Guided Salvage Therapy in the USA: A Real Life Experience
ConclusionsThe success rate of AST-guided salvage therapy in the USA is low particularly in those with high BMI. Bismuth-based therapy appears to be better than non-bismuth-based regimens. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - December 20, 2017 Category: Gastroenterology Source Type: research

Gas6 as a predictor of esophageal varices in patients affected by hepatitis C virus related-chronic liver disease.
Authors: Bellan M, Sainaghi PP, Minh MT, Minisini R, Molinari L, Baldrighi M, Salmi L, Barbaglia MN, Castello LM, Ravanini P, Avanzi GC, Pirisi M Abstract AIM: Plasma Gas6 was tested as an alternative to Baveno VI criteria (liver stiffness 150 × 109/l) in an endoscopy-sparing strategy. METHODS:  A total of 160 patients with chronic hepatitis C and advanced fibrosis/cirrhosis underwent, on the same occasion, liver elastography, upper endoscopy, a platelet count and serum Gas6 measurement Results: A total of 74/160 (46%) patients had esophageal varices, that were small (diameter 
Source: Future Medicine: Biomarkers in Medicine - December 17, 2017 Category: Internal Medicine Tags: Biomark Med Source Type: research

Non-endoscopic biopsy techniques: a review.
Authors: Otuya DO, Verma Y, Farrokhi H, Higgins L, Rosenberg M, Damman C, Tearney GJ Abstract INTRODUCTION: Diseases of the stomach and small intestine account for approximately 20% of all gastrointestinal (GI)-related mortality. Biopsy of the stomach and small intestine remains a key diagnostic tool for most of the major diseases that affect the GI tract. While endoscopic means for obtaining biopsy is generally the standard of care, it has several limitations that make it less ideal for pediatric patients and in low resource areas of the world. Therefore, non-endoscopic means for obtaining biopsy samples is of int...
Source: Expert Review of Gastroenterology and Hepatology - December 17, 2017 Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research

Imaging Manifestations of Peptic Ulcer Disease on Computed Tomography
This article highlights imaging features of uncomplicated PUD on CT imaging in order to allow for early detection of this disease process on imaging and the prevention of potential high-grade complications by recommending esophagogastroduodenoscopy. (Source: Seminars in Ultrasound, CT and MRI)
Source: Seminars in Ultrasound, CT and MRI - December 16, 2017 Category: Radiology Source Type: research

Delayed Iatrogenic Diaphragmatic Hernia after Left Lower Lobectomy.
Authors: Hong TH, Choi YS Abstract A 66-year-old patient undergoing regular follow-up at Samsung Medical Center after left lower lobectomy visited the emergency department around 9 months postoperatively because of nausea and vomiting after routine esophagogastroduodenoscopy at a local clinic. Abdominal computed tomography showed the stomach herniating into the left thoracic cavity. We explored the pleural cavity via video-assisted thoracic surgery (VATS). Adhesiolysis around the herniated stomach and laparotomic reduction under video assistance were successfully performed. The diaphragmatic defect was repaired via...
Source: Korean Journal of Thoracic and Cardiovascular Surgery - December 15, 2017 Category: Cardiovascular & Thoracic Surgery Tags: Korean J Thorac Cardiovasc Surg Source Type: research

Phlegmonous Esophagitis Treated with Internal Drainage and Feeding Jejunostomy.
We report the case of a 67-year-old woman presenting with epigastric pain. Computed tomography identified diffuse phlegmonous esophagitis. Esophagogastroduodenoscopy revealed multiple perforations in the mucosal layer of the esophagus. A large amount of pus was drained internally through the gut. The patient was treated with antibiotics and early jejunostomy feeding. Although phlegmonous esophagitis is a potentially fatal disease, the patient was successfully treated medically with only a minor complication (esophageal stricture). PMID: 29234613 [PubMed] (Source: Korean Journal of Thoracic and Cardiovascular Surgery)
Source: Korean Journal of Thoracic and Cardiovascular Surgery - December 15, 2017 Category: Cardiovascular & Thoracic Surgery Tags: Korean J Thorac Cardiovasc Surg Source Type: research