Severe Anemia from Multiple Gastric Hyperplastic Polyps in a Hemodialysis Patient after Long-term Use of a Proton-pump Inhibitor
Intern Med. 2024;63(5):649-657. doi: 10.2169/internalmedicine.2091-23.ABSTRACTA 90-year-old man on maintenance hemodialysis was admitted due to severe symptomatic anemia. Biopsies under esophagogastroduodenoscopy demonstrated that the cause of anemia was intermittent blood oozing from multiple gastric hyperplastic polyps. Even after successful eradication of Helicobacter pylori, he showed hypergastrinemia (480 pg/mL) owing to esomeprazole (proton-pump inhibitor) therapy for the past 4.5 years to treat reflux esophagitis. Seven months after we switched esomeprazole to famotidine (H2-receptor antagonist), those gastric polyp...
Source: Internal Medicine - March 3, 2024 Category: Internal Medicine Authors: Shiyo Ikeda Toshiya Takahashi Toshitsugu Tandoh Kaori Ushiyama Yujiro Kida Source Type: research
A Case of Refractory Gastroesophageal Reflux Disease Successfully Treated with Endoscopic Anti-gastroesophageal Reflux Mucosal Resection by the ESD-G Method (with video)
Intern Med. 2024 Mar 4. doi: 10.2169/internalmedicine.3305-23. Online ahead of print.ABSTRACTA 70-year-old man who had undergone treatment for gastroesophageal reflux disease (GERD) by a family doctor presented to our hospital with severe heartburn and dysphagia despite taking vonoprazan (20 mg) for 3 months. A diagnosis of vonoprazan-refractory nonerosive reflux disease was made based on esophagogastroduodenoscopy and esophageal function examinations. The patient elected to undergo endoscopic treatment for GERD. Therefore, we performed endoscopic treatment using the endoscopic submucosal dissection (ESD-G) technique devel...
Source: Internal Medicine - March 3, 2024 Category: Internal Medicine Authors: Shun Sasaki Kazuhiro Ota Taro Iwatsubo Noriaki Sugawara Akitoshi Hakoda Hironori Tanaka Yosuke Mori Toshihisa Takeuchi Kazuhide Higuchi Hiroki Nishikawa Source Type: research
Severe Anemia from Multiple Gastric Hyperplastic Polyps in a Hemodialysis Patient after Long-term Use of a Proton-pump Inhibitor
Intern Med. 2024;63(5):649-657. doi: 10.2169/internalmedicine.2091-23.ABSTRACTA 90-year-old man on maintenance hemodialysis was admitted due to severe symptomatic anemia. Biopsies under esophagogastroduodenoscopy demonstrated that the cause of anemia was intermittent blood oozing from multiple gastric hyperplastic polyps. Even after successful eradication of Helicobacter pylori, he showed hypergastrinemia (480 pg/mL) owing to esomeprazole (proton-pump inhibitor) therapy for the past 4.5 years to treat reflux esophagitis. Seven months after we switched esomeprazole to famotidine (H2-receptor antagonist), those gastric polyp...
Source: Internal Medicine - March 3, 2024 Category: Internal Medicine Authors: Shiyo Ikeda Toshiya Takahashi Toshitsugu Tandoh Kaori Ushiyama Yujiro Kida Source Type: research
A Case of Refractory Gastroesophageal Reflux Disease Successfully Treated with Endoscopic Anti-gastroesophageal Reflux Mucosal Resection by the ESD-G Method (with video)
Intern Med. 2024 Mar 4. doi: 10.2169/internalmedicine.3305-23. Online ahead of print.ABSTRACTA 70-year-old man who had undergone treatment for gastroesophageal reflux disease (GERD) by a family doctor presented to our hospital with severe heartburn and dysphagia despite taking vonoprazan (20 mg) for 3 months. A diagnosis of vonoprazan-refractory nonerosive reflux disease was made based on esophagogastroduodenoscopy and esophageal function examinations. The patient elected to undergo endoscopic treatment for GERD. Therefore, we performed endoscopic treatment using the endoscopic submucosal dissection (ESD-G) technique devel...
Source: Internal Medicine - March 3, 2024 Category: Internal Medicine Authors: Shun Sasaki Kazuhiro Ota Taro Iwatsubo Noriaki Sugawara Akitoshi Hakoda Hironori Tanaka Yosuke Mori Toshihisa Takeuchi Kazuhide Higuchi Hiroki Nishikawa Source Type: research
Severe Anemia from Multiple Gastric Hyperplastic Polyps in a Hemodialysis Patient after Long-term Use of a Proton-pump Inhibitor
Intern Med. 2024;63(5):649-657. doi: 10.2169/internalmedicine.2091-23.ABSTRACTA 90-year-old man on maintenance hemodialysis was admitted due to severe symptomatic anemia. Biopsies under esophagogastroduodenoscopy demonstrated that the cause of anemia was intermittent blood oozing from multiple gastric hyperplastic polyps. Even after successful eradication of Helicobacter pylori, he showed hypergastrinemia (480 pg/mL) owing to esomeprazole (proton-pump inhibitor) therapy for the past 4.5 years to treat reflux esophagitis. Seven months after we switched esomeprazole to famotidine (H2-receptor antagonist), those gastric polyp...
Source: Internal Medicine - March 3, 2024 Category: Internal Medicine Authors: Shiyo Ikeda Toshiya Takahashi Toshitsugu Tandoh Kaori Ushiyama Yujiro Kida Source Type: research
The Clinical Effect of Octreotide Combined with Upper Endoscopy in the Treatment of Peptic Ulcer Complicated with Upper Gastrointestinal Hemorrhage
CONCLUSION AND RELEVANCE: Combining octreotide and upper endoscopy has affirmative efficacy and good hemostatic effect on treating peptic ulcer complicated with upper gastrointestinal hemorrhage with less pain and short recovery time, which is worthy of clinical application.PMID:38430179 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Di Zhou Peiyu Zhao Huihui Yang Source Type: research
The Clinical Effect of Octreotide Combined with Upper Endoscopy in the Treatment of Peptic Ulcer Complicated with Upper Gastrointestinal Hemorrhage
CONCLUSION AND RELEVANCE: Combining octreotide and upper endoscopy has affirmative efficacy and good hemostatic effect on treating peptic ulcer complicated with upper gastrointestinal hemorrhage with less pain and short recovery time, which is worthy of clinical application.PMID:38430179 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Di Zhou Peiyu Zhao Huihui Yang Source Type: research
The Clinical Effect of Octreotide Combined with Upper Endoscopy in the Treatment of Peptic Ulcer Complicated with Upper Gastrointestinal Hemorrhage
CONCLUSION AND RELEVANCE: Combining octreotide and upper endoscopy has affirmative efficacy and good hemostatic effect on treating peptic ulcer complicated with upper gastrointestinal hemorrhage with less pain and short recovery time, which is worthy of clinical application.PMID:38430179 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Di Zhou Peiyu Zhao Huihui Yang Source Type: research
The Clinical Effect of Octreotide Combined with Upper Endoscopy in the Treatment of Peptic Ulcer Complicated with Upper Gastrointestinal Hemorrhage
CONCLUSION AND RELEVANCE: Combining octreotide and upper endoscopy has affirmative efficacy and good hemostatic effect on treating peptic ulcer complicated with upper gastrointestinal hemorrhage with less pain and short recovery time, which is worthy of clinical application.PMID:38430179 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Di Zhou Peiyu Zhao Huihui Yang Source Type: research
The Clinical Effect of Octreotide Combined with Upper Endoscopy in the Treatment of Peptic Ulcer Complicated with Upper Gastrointestinal Hemorrhage
CONCLUSION AND RELEVANCE: Combining octreotide and upper endoscopy has affirmative efficacy and good hemostatic effect on treating peptic ulcer complicated with upper gastrointestinal hemorrhage with less pain and short recovery time, which is worthy of clinical application.PMID:38430179 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Di Zhou Peiyu Zhao Huihui Yang Source Type: research
The Clinical Effect of Octreotide Combined with Upper Endoscopy in the Treatment of Peptic Ulcer Complicated with Upper Gastrointestinal Hemorrhage
CONCLUSION AND RELEVANCE: Combining octreotide and upper endoscopy has affirmative efficacy and good hemostatic effect on treating peptic ulcer complicated with upper gastrointestinal hemorrhage with less pain and short recovery time, which is worthy of clinical application.PMID:38430179 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Di Zhou Peiyu Zhao Huihui Yang Source Type: research
The Clinical Effect of Octreotide Combined with Upper Endoscopy in the Treatment of Peptic Ulcer Complicated with Upper Gastrointestinal Hemorrhage
CONCLUSION AND RELEVANCE: Combining octreotide and upper endoscopy has affirmative efficacy and good hemostatic effect on treating peptic ulcer complicated with upper gastrointestinal hemorrhage with less pain and short recovery time, which is worthy of clinical application.PMID:38430179 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Di Zhou Peiyu Zhao Huihui Yang Source Type: research
Gastric fundic gland polyposis and cancer development after eradication of Helicobacter pylori in patient with gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS)
AbstractA 44-year-old woman with gastric cancer (GC) and fundic gland polyposis (FGPs) was referred to our hospital for further diagnosis and treatment. She successfully underwent eradication therapy for Helicobacter pylori (HP) 6 years ago, but did not exhibit FGPs at that time. When she underwent an esophagogastroduodenoscopy 2, 4, and 5 years after the eradication of HP, her imaging results revealed the existence of FGPs which gradually increased in her gastric fundus and body. Gastric adenocarcinoma and proximal polypo sis of the stomach (GAPPS) was suspected and a mutational analysis was performed, revealing anAPC ...
Source: Gastric Cancer - February 26, 2024 Category: Gastroenterology Source Type: research
Case report: Pathological complete response of pregnancy associated pulmonary enteric adenocarcinoma to chemoradiotherapy
This report describes the case of a 28-year-old woman with pregnancy-related PEAC who presented with left shoulder pain. A superior sulcus tumor was identified in the left thoracic cavity, and the biopsy indicated more than 50% intestinal differentiation components. Moreover, immunohistochemical staining revealed positive CDX2 and CK7 expression. Positron emission tomography-computed tomography, upper endoscopy, colonoscopy, and small intestinal capsule endoscopy revealed no gastrointestinal malignancies. The patient was diagnosed with locally advanced PEAC (clinical stage T4N0M0; stage IIIA). Therefore, the patient was tr...
Source: Frontiers in Oncology - February 23, 2024 Category: Cancer & Oncology Source Type: research
Multiple duodenal epithelial tumors in a patient with polymerase proofreading-associated polyposis in POLE variant
Clin J Gastroenterol. 2024 Feb 22. doi: 10.1007/s12328-024-01922-1. Online ahead of print.ABSTRACTPolymerase proofreading-associated polyposis (PPAP) is a rare disease with autosomal-dominant inheritance caused by germline variants in the POLE and POLD1 genes. PPAP has been reported to increase the risk of multiple cancers, including colon, duodenal, and endometrial cancers. Herein, we report a case in which multiple duodenal tumors led to the detection of a POLE mutation. A 43-year-old woman underwent esophagogastroduodenoscopy (EGD). Multiple duodenal tumors were detected, and all lesions were treated endoscopically. The...
Source: Clinical Colorectal Cancer - February 22, 2024 Category: Cancer & Oncology Authors: Hajime Miyazaki Osamu Dohi Eiko Maeda Atsushi Tomioka Naohisa Yoshida Yukiko Morinaga Yoshito Itoh Hideki Ishikawa Source Type: research
