A Curious Case of Primary Gastric Mucosal Melanoma
We present the case of a 58-year-old woman with complaints of abdominal pain, loss of appetite and weight. Esophagogastroduodenoscopy revealed a gastric mass and systemic imaging demonstrated widespread nodal and bilateral adrenal gland involvement. Histopathology of the gastric mass confirmed primary malignant mucosal melanoma of the stomach. The patient received three cycles of Nivolumab but did not respond, and thus, was then offered best supportive care. Although infrequent, mucosal melanoma can arise from the gastrointestinal tract, and in contrast to the cutaneous form, advanced disease usually has a dismal prognosis...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Zahabia Sohail Mirza Rameez Samar Neelam Jawed Qureshi Sidra Arshad Adeeba Zaki Source Type: research
Gastrointestinal bleeding in children: diagnostic approach
AbstractDifferent conditions may underlie gastrointestinal bleeding (GIB) in children. The estimated prevalence of GIB in children is 6.4%, with spontaneous resolution in approximately 80% of cases. Nonetheless, the initial approach plays a pivotal role in determining the prognosis. The priority is the stabilization of hemodynamic status, followed by a systematic diagnostic approach. GIB can originate from either upper or lower gastrointestinal tract, leading to a broad differential diagnosis in infants and children. This includes benign and self-limiting disorders, alongside serious conditions necessitating immediate trea...
Source: Italian Journal of Pediatrics - January 23, 2024 Category: Pediatrics Source Type: research
Hookworm infestation as a rare cause of melaena in tropics: A case report
Trop Doct. 2024 Jan 21:494755231226356. doi: 10.1177/00494755231226356. Online ahead of print.ABSTRACTMelaena due to hookworm infestation is a rare clinical presentation. It usually presents with symptoms of iron-deficiency anaemia owing to slow blood loss. Here we present a case of 45-year male who presented with a one-year history of intermittent melena requiring multiple blood transfusions. Preliminary endoscopies at different centres were normal. The presence of hookworm in the duodenum was only detected on repeat upper endoscopy as the cause of blood loss, and treatment with albendazole was successful in curing the pa...
Source: Tropical Doctor - January 22, 2024 Category: Tropical Medicine Authors: Narendra Pandit Sameer Bhattarai Dinesh Nalbo Sanjay Yadav Source Type: research
Prevalence and risk factors for medication-refractory reflux esophagitis in patients with systemic sclerosis in Japan
ConclusionsPatients with persistent reflux symptoms and those with absent contractility and GEFV grade III or IV should receive maintenance therapy with strong acid inhibition to prevent medication-refractory RE. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - January 22, 2024 Category: Gastroenterology Source Type: research
Can my surgeon scope? Trends in endoscopy training volume and experience among general surgery residents in the United States: a nationwide analysis
ConclusionThe overall endoscopy volume for general surgery residents has largely remained stable, with a minor increase in esophagogastroduodenoscopy and no change in colonoscopy. Future research should investigate whether simulation-based exercises can bridge the gap between procedural volume and learning curve requirements for endoscopy. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - January 19, 2024 Category: Surgery Source Type: research
Management of an Ingested Foreign Body in a COVID-Positive Patient
Anesth Prog. 2023 Dec 1;70(4):178-183. doi: 10.2344/anpr-70-03-03.ABSTRACTThis case report describes a 51-year-old man who swallowed an amalgam fragment dislodged during dental treatment performed without a throat screen. The patient was transferred to the emergency department, where the foreign body was confirmed to be in the esophagus following radiographic imaging. Foreign body removal from the esophagus is routinely achieved via esophagogastroduodenoscopy (EGD). However, this incident occurred in September 2020, at the height of the COVID-19 pandemic. Because of the patient's preoperative positive COVID-19 test, the op...
Source: Anesthesia Progress - January 15, 2024 Category: Anesthesiology Authors: Tiffany Smith Rachel Blum Raquel Rozdolski Source Type: research
