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The Persistence of Nystatin Use for Dermatophyte Infections
DISCUSSION: Physicians are continuing to use nystatin for the treatment of tinea infections. Dermatologists have discontinued this treatment regimen, whereas other specialties have an opportunity to further improve their knowledge in this regard. J Drugs Dermatol. 2023;22(12):e49-e50.     doi:10.36849/JDD.5606e.PMID:38051827 | DOI:10.36849/JDD.5606 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - December 5, 2023 Category: Dermatology Authors: Suraj Muddasani Gabrielle Rivin Alan B Fleischer Source Type: research

Therapeutic effect of iturin A on < em > Candida albicans < /em > oral infection and its pathogenic factors
This study aimed to explore the influence of iturin A on several pathogenic attributes of C. albicans, including hypha formation, cell membrane permeability, cell adhesion, biofilm formation, and therapeutic efficacy in an oral C. albicans infection model in mice. The minimal inhibitory concentration of iturin A against C. albicans was determined to be 25 µg/mL in both YEPD and RPMI-1640 media. Iturin A effectively inhibited C. albicans hyphal formation, decreased cell viability within biofilms, enhanced cell membrane permeability, and disrupted cell adhesion in vitro. Nonetheless, iturin A did not significantly affect th...
Source: Antimicrobial Agents and Chemotherapy - December 5, 2023 Category: Microbiology Authors: Di Han Yulan Ji Saixue Yang Pei Song Yihong Shi Dongyan Shao Xianqing Chen Li Shang Junling Shi Chunmei Jiang Source Type: research