Noni enhances the anticancer activity of cyclophosphamide and suppresses myelotoxicity and hepatotoxicity in tumor-bearing mice
CONCLUSIONS: The present study suggested that CYL treatment can cause serious myelotoxicity and hepatic injury in cancer patients. In conclusion, the combined use of noni with CYL potentially enhances the antitumor activity of CYL and suppresses myelotoxicity and hepatotoxicity induced by CYL in tumor-bearing mice.PMID:38662247 | DOI:10.1007/s00432-024-05734-1 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 25, 2024 Category: Cancer & Oncology Authors: Mohammad Ali S N Manjula Ishfaq Mohiuddin K Mruthunjaya Faiyaz Shakeel Suhail Ahmad Mir Shahid Ud Din Wani Source Type: research
Noni enhances the anticancer activity of cyclophosphamide and suppresses myelotoxicity and hepatotoxicity in tumor-bearing mice
CONCLUSIONS: The present study suggested that CYL treatment can cause serious myelotoxicity and hepatic injury in cancer patients. In conclusion, the combined use of noni with CYL potentially enhances the antitumor activity of CYL and suppresses myelotoxicity and hepatotoxicity induced by CYL in tumor-bearing mice.PMID:38662247 | DOI:10.1007/s00432-024-05734-1 (Source: Cell Research)
Source: Cell Research - April 25, 2024 Category: Cytology Authors: Mohammad Ali S N Manjula Ishfaq Mohiuddin K Mruthunjaya Faiyaz Shakeel Suhail Ahmad Mir Shahid Ud Din Wani Source Type: research
Noni enhances the anticancer activity of cyclophosphamide and suppresses myelotoxicity and hepatotoxicity in tumor-bearing mice
CONCLUSIONS: The present study suggested that CYL treatment can cause serious myelotoxicity and hepatic injury in cancer patients. In conclusion, the combined use of noni with CYL potentially enhances the antitumor activity of CYL and suppresses myelotoxicity and hepatotoxicity induced by CYL in tumor-bearing mice.PMID:38662247 | DOI:10.1007/s00432-024-05734-1 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 25, 2024 Category: Cancer & Oncology Authors: Mohammad Ali S N Manjula Ishfaq Mohiuddin K Mruthunjaya Faiyaz Shakeel Suhail Ahmad Mir Shahid Ud Din Wani Source Type: research
Repellent and larvicidal properties of selected indigenous plants in the control of Anopheles mosquitoes
CONCLUSION: The results obtained indicated that seed oil of Morinda citrifolia, essential oil of Ocimum basilicum, and crude extract of Moringa oleifera have repellent activity against An. gambiae s.l. The complete protection time (CPT) of Morinda citrifolia, Moringa oleifera, and Ocimum basilicum was 120 min, 72 min and 84 min at ED99.9 respectively. Morinda citrifolia oil exhibited larvicidal effects against the larvae of An. gambiae s.l. The results provide valuable information for the use of the plants as biocides.PMID:38648410 | DOI:10.4103/0972-9062.392267 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 22, 2024 Category: Infectious Diseases Authors: Obadiah Opoku-Bamfoh Sandra Abankwa Kwarteng Frema A N Owusu Raphael Akpanya Kelvin A Mensah Mercy Badu Fred Y Gyamfi Victoria Sogbo Ebenezer J D Belford Abena Boakye Henry Morgan Morrison Patrick K Obuam Sylvester Coleman Source Type: research
Morinda citrifolia leaf assisted synthesis of ZnO decorated Ag bio-nanocomposites for in-vitro cytotoxicity, antimicrobial and anticancer applications
This study used Morinda citrifolia leaf (MCL) extract to synthesise Zinc oxide nanoparticles (ZnO NPs) and ZnO decorated silver nanocomposites (ZnO/Ag NCs). The synthesized nanomaterials structural morphology and crystallinity were characterized using a Field emission scanning electron microscope (FESEM) and X-ray diffraction (XRD) analysis. The antimicrobial activity of ZnO NPs and ZnO/Ag NCs was evaluated using human nosocomial bacterial pathogens. The highest antimicrobial activity was recorded for ZnO/Ag NCs at the minimum inhibitory concentration (MIC) at 80 and 100 μg/mL for Escherichia coli, Pseudomonas aeruginosa ...
Source: Bioprocess and Biosystems Engineering - March 21, 2024 Category: Biomedical Engineering Authors: Gopinath Venkatraman Priyadarshini Sakthi Mohan Puteri Shafinaz Abdul-Rahman Faridah Sonsudin Barathan Muttiah Abdurahman Hajinur Hirad Abdullah A Alarfaj Shifa Wang Source Type: research
Morinda citrifolia leaf assisted synthesis of ZnO decorated Ag bio-nanocomposites for in-vitro cytotoxicity, antimicrobial and anticancer applications
This study used Morinda citrifolia leaf (MCL) extract to synthesise Zinc oxide nanoparticles (ZnO NPs) and ZnO decorated silver nanocomposites (ZnO/Ag NCs). The synthesized nanomaterials structural morphology and crystallinity were characterized using a Field emission scanning electron microscope (FESEM) and X-ray diffraction (XRD) analysis. The antimicrobial activity of ZnO NPs and ZnO/Ag NCs was evaluated using human nosocomial bacterial pathogens. The highest antimicrobial activity was recorded for ZnO/Ag NCs at the minimum inhibitory concentration (MIC) at 80 and 100 μg/mL for Escherichia coli, Pseudomonas aeruginosa ...
Source: Bioprocess and Biosystems Engineering - March 21, 2024 Category: Biomedical Engineering Authors: Gopinath Venkatraman Priyadarshini Sakthi Mohan Puteri Shafinaz Abdul-Rahman Faridah Sonsudin Barathan Muttiah Abdurahman Hajinur Hirad Abdullah A Alarfaj Shifa Wang Source Type: research
Morinda citrifolia leaf assisted synthesis of ZnO decorated Ag bio-nanocomposites for in-vitro cytotoxicity, antimicrobial and anticancer applications
This study used Morinda citrifolia leaf (MCL) extract to synthesise Zinc oxide nanoparticles (ZnO NPs) and ZnO decorated silver nanocomposites (ZnO/Ag NCs). The synthesized nanomaterials structural morphology and crystallinity were characterized using a Field emission scanning electron microscope (FESEM) and X-ray diffraction (XRD) analysis. The antimicrobial activity of ZnO NPs and ZnO/Ag NCs was evaluated using human nosocomial bacterial pathogens. The highest antimicrobial activity was recorded for ZnO/Ag NCs at the minimum inhibitory concentration (MIC) at 80 and 100 μg/mL for Escherichia coli, Pseudomonas aeruginosa ...
Source: Bioprocess and Biosystems Engineering - March 21, 2024 Category: Biomedical Engineering Authors: Gopinath Venkatraman Priyadarshini Sakthi Mohan Puteri Shafinaz Abdul-Rahman Faridah Sonsudin Barathan Muttiah Abdurahman Hajinur Hirad Abdullah A Alarfaj Shifa Wang Source Type: research
Morindone as a potential therapeutic compound targeting TP53 and KRAS mutations in colorectal cancer cells
In conclusion, morindone could be a competitive therapeutic agent in CRC by exhibiting multiple mechanism of anti-cancer actions.PMID:38423379 | DOI:10.1016/j.cbi.2024.110928 (Source: Chemico-Biological Interactions)
Source: Chemico-Biological Interactions - February 29, 2024 Category: Molecular Biology Authors: Cheok Wui Chee Najihah Mohd Hashim Nurshamimi Nor Rashid Source Type: research
Morindone as a potential therapeutic compound targeting TP53 and KRAS mutations in colorectal cancer cells
In conclusion, morindone could be a competitive therapeutic agent in CRC by exhibiting multiple mechanism of anti-cancer actions.PMID:38423379 | DOI:10.1016/j.cbi.2024.110928 (Source: Chemico-Biological Interactions)
Source: Chemico-Biological Interactions - February 29, 2024 Category: Molecular Biology Authors: Cheok Wui Chee Najihah Mohd Hashim Nurshamimi Nor Rashid Source Type: research
