Storage stability and in vitro digestion of microencapsulated powder containing fermented noni juice and probiotics
Publication date: Available online 23 August 2020Source: Food BioscienceAuthor(s): Chuang Zhang, Siew Young Quek, Nan Fu, Yuwen Su, Paul A. Kilmartin, Xiao Dong Chen (Source: Food Bioscience)
Source: Food Bioscience - August 24, 2020 Category: Food Science Source Type: research

Enhanced anti-cancer activity of chitosan loaded Morinda citrifolia essential oil against A549 human lung cancer cells.
Abstract In the present study, the chemical composition of Morinda citrifolia essential oils was determined by gas chromatography-mass spectrometry and was found to contain several anti-cancer compounds including L-scopoletin, nordamnacanthal, β-morindone, α-copaene, 9-H-pyrido[3,4-b]indole, β-thujene and terpinolene. The physico-chemical characterization of chitosan, chitosan nanoparticles and Morinda citrifolia essential oils loaded chitosan nanoparticles combination was carried out by Fourier transform infrared spectroscopy, powder X-ray diffraction and dynamic light scattering coupled with zeta pote...
Source: International Journal of Biological Macromolecules - August 23, 2020 Category: Biochemistry Authors: Rajivgandhi G, Saravanan K, Ramachandran G, Li JL, Yin L, Quero F, Alharbi NS, Kadaikunnan S, Khaled JM, Manoharan N, Li WJ Tags: Int J Biol Macromol Source Type: research

The Effects of Morinda citrifolia (Noni) on the Cellular Viability and Osteogenesis of Stem Cell Spheroids.
Conclusions: Based on these findings, we concluded that Noni extract might be applied for the enhanced osteogenic differentiation of stem cell spheroids. PMID: 32764294 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - August 4, 2020 Category: Universities & Medical Training Authors: Min SK, Oh J, Park JB Tags: Medicina (Kaunas) Source Type: research

Efficacy of an aqueous Morinda citrifolia fruit extract-phytosome gel in treating oral inflammatory ulcer in rabbit model.
CONCLUSION: These findings demonstrated that 10% AMFE-P gel has potential as a safe and effective alternative therapeutic agent for oral ulcers. PMID: 32651964 [PubMed - as supplied by publisher] (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - July 10, 2020 Category: Biotechnology Authors: Kongpuckdee S, Ungphaiboon S, Sungkharak S, Phadoongsombut N, Mahattanadul S Tags: Curr Pharm Biotechnol Source Type: research

Morinda citrifolia (Noni) Juice Suppresses A549 Human Lung Cancer Cells via Inhibiting AKT/Nuclear Factor- κ B Signaling Pathway
ConclusionNoni juice inhibited the proliferation of A549 lung cancer cells, induced apoptosis, and inhibited cell invasion and migration via regulating AKT/NF- κ B signaling pathway. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 8, 2020 Category: Internal Medicine Source Type: research

Effects of noni fruit and fermented noni juice against acute alcohol induced liver injury in mice
Publication date: July 2020Source: Journal of Functional Foods, Volume 70Author(s): Min Guo, Bingyong Mao, Faizan Ahmed Sadiq, Yujie Hao, Shumao Cui, Meihua Yi, Qi'en Hong, Yuan-Kun Lee, Jianxin Zhao (Source: Journal of Functional Foods)
Source: Journal of Functional Foods - May 9, 2020 Category: Nutrition Source Type: research

Chemical composition and bioactivity of essential oil from Morinda citrifolia L. fruit
Morinda citrifolia has aroused the interest of several research institutions due to its pharmacological properties. The compounds biosynthesized can be explored as an alternative for control measures of plant pathogens causing leaf lesions in maize. The study aim at evaluating the potential effects of essential oil obtained from ripe fruits of M. citrifolia on Bipolaris maydis and Exserohilu... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - April 22, 2020 Category: Complementary Medicine Source Type: research

Ultraviolet A protective potential of plant extracts and phytochemicals.
This article includes 17 well standardized plant extracts (Camellia sinensis (L.) Kuntze, Silybum marianum L. Gaertn., Punica granatum L., Polypodium aureum L., Vaccinium myrtillus L., Lonicera caerulea L., Thymus vulgaris L., Opuntia ficus-indica (L.) Mill., Morinda citrifolia L., Aloe vera (L.) Burm.f., Oenothera paradoxa Hudziok, Galinsoga parviflora Cav., Galinsoga quadriradiata Ruiz et Pavón, Hippophae rhamnoides L., Cola acuminata Schott & Endl., Theobroma cacao L. and Amaranthus cruentus L.) and 26 phytochemicals. PMID: 32188958 [PubMed - as supplied by publisher] (Source: Biomedical Papers of the Medic...
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - March 20, 2020 Category: Biomedical Science Tags: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Source Type: research

[ASAP] Isolation and Structural Characterization of Specific Bacterial ß-Glucuronidase Inhibitors from Noni ( < italic toggle="yes" > Morinda citrifolia < /italic > ) Fruits
Journal of Natural ProductsDOI: 10.1021/acs.jnatprod.9b00279 (Source: Journal of Natural Products)
Source: Journal of Natural Products - February 21, 2020 Category: Biochemistry Authors: Fei Yang, Wenjun Zhu, Shi Sun, Qing Ai, Paba Edirisuriya, and Kequan Zhou* Source Type: research

Physicochemical properties, antioxidant and antiproliferative activities of polysaccharides from Morinda citrifolia L. (Noni) based on different extraction methods.
Abstract The influences of different extraction methods on the yields, physicochemical properties, antioxidant activities and antiproliferative abilities of polysaccharides from Morinda citrifolia L. (Noni) were investigated and compared. Three extraction methods were applied to extract Noni polysaccharides (NP), which include hot water extraction (HWE), pulsed electric field-assisted extraction (PEFAE) and ultrasonic-assisted extraction (UAE). The extraction yields, sugar contents, uronic acid contents, molecular weights, monosaccharide proportions, antioxidant activities and antiproliferative abilities o...
Source: International Journal of Biological Macromolecules - January 28, 2020 Category: Biochemistry Authors: Li J, Niu D, Zhang Y, Zeng XA Tags: Int J Biol Macromol Source Type: research

Molecules, Vol. 25, Pages 160: Comparison of Anthraquinones, Iridoid Glycosides and Triterpenoids in Morinda officinalis and Morinda citrifolia Using UPLC/Q-TOF-MS and Multivariate Statistical Analysis
In this study, a ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF-MS)-based approach and a multivariate statistical analysis (MSA) were adopted to compare the difference in the chemical compounds present in the root extract of M. officinalis and M. citrifolia. There were 26 anthraquinones, 15 triterpenes, and 8 iridoid glycosides identified in the root extracts of M. officinalis, 30 anthraquinones, 1 triterpene, and 8 iridoid glycosides in the root extracts of M. citrifolia. Among these, 25 compounds presented in both plants. In addition, a principal component analysis (PCA) s...
Source: Molecules - December 30, 2019 Category: Chemistry Authors: Wang Wang Yang Yan Feng Wang Tags: Article Source Type: research

Exploring the effects of microencapsulation on odour retention of fermented noni juice
Publication date: Available online 23 December 2019Source: Journal of Food EngineeringAuthor(s): Chuang Zhang, Xiao Chen, Jingying Zhang, Paul A. Kilmartin, Siew Young QuekAbstractThe key volatiles of fermented noni juice (FNJ) were identified, and the effect of microencapsulation (via spray drying and freeze drying) on the volatile profile of FNJ powders was investigated. Results showed that hexanoic acid was the major contributor to the unpleasant odour of FNJ. Both drying methods significantly reduced (p < 0.05) the retention of volatiles, and changed the volatile profile of the resulting powders. Comparing the two ...
Source: Journal of Food Engineering - December 24, 2019 Category: Food Science Source Type: research

Genomics Analysis of L-DOPA Exposure in Drosophila sechellia
In this study, we aim to identify new genes important for host specialization by profiling gene expression response to 3,4-dihydroxyphenylalanine (L-DOPA). Recent work found it to be highly abundant in M. citrifolia, critical for reproductive success of D. sechellia, and supplementation of diet with the downstream pathway product dopamine can influence toxin resistance phenotypes in related species. Here we used a combination of functional genetics and genomics techniques to identify new genes that are important for D. sechellia ecological adaptation to this new niche. We show that L-DOPA exposure can affect toxin resistan...
Source: G3: Genes Genomes Genetics - December 2, 2019 Category: Genetics & Stem Cells Authors: Lanno, S. M., Lam, I., Drum, Z., Linde, S. C., Gregory, S. M., Shimshak, S. J., Becker, M. V., Brew, K. E., Budhiraja, A., Carter, E. A., Chigweshe, L., Collins, K. P., Earley, T., Einstein, H. L., Fan, A. A., Goss, S. S., Hagen, E. R., Hutcheon, S. B., K Tags: Investigations Source Type: research

Immunomodulatory actions of a Polynesian herb Noni (Morinda citrifolia) and its clinical applications.
Abstract Morinda citrifolia (Noni) is a popular traditional medicinal plant consumed in various forms in several countries around the world as a complementary and alternative treatment due to its established health benefits. Noni is rich in bioactive substances and has significantly exhibited pro-oxidant and immunomodulatory effects. In this review, we highlight the pharmacological basis related to the phytochemicals and polysaccharides present in Noni and its potential therapeutic effects. We screened electronic databases such as PubMed, Google Scholar, Scopus for scientific literature. Our results indica...
Source: Complementary Therapies in Medicine - November 30, 2019 Category: Complementary Medicine Authors: Lohani M, Majrashi M, Govindarajulu M, Patel M, Ramesh S, Bhattacharya D, Joshi S, Fadan M, Nadar R, Darien B, Maurice DV, Kemppainen B, Dhanasekaran M Tags: Complement Ther Med Source Type: research

Molecular characterization of a novel potyvirus infecting noni
AbstractThe complete genomic sequence of a novel potyvirus from a noni plant in China (Morinda citrifolia) with foliar mosaic and chlorotic symptoms was determined. The genomic RNA consists of 9645 nucleotides (nt) excluding the poly(A) tail, containing the typical open reading frame (ORF) of potyviruses and encoding a large putative polyprotein of 3077 amino acids (aa). Pairwise comparisons showed that the virus shares 48.8% –58.5% sequence identity at the genome sequence level, and 38.5%–53.4% identity at the polyprotein sequence level with other members of the genusPotyvirus. Phylogenetic analysis indicated that the...
Source: Archives of Virology - October 31, 2019 Category: Virology Source Type: research