The ethyl acetate fraction of a methanolic extract of unripe noni (Morinda citrifolia Linn.) fruit exhibits a biphasic effect on the dopaminergic system in mice.
This study examined the effect of the ethyl acetate fraction of a methanolic extract of unripe Morinda citrifolia Linn. fruit (EA-MMC; 5-100 mg/kg, p.o.) on the dopaminergic system using mouse models of apomorphine-induced climbing time and climbing behavior, methamphetamine-induced stereotypy (sniffing, biting, gnawing, and licking) and haloperidol-induced catalepsy using the bar test. Acute treatment with EA-MMC at a low dose (25 mg/kg, p.o.) significantly attenuated the apomorphine-induced climbing time and climbing behavior in mice. Similarly, EA-MMC (5 and 10 mg/kg, p.o.) significantly inhibited methamphetamine-induce...
Source: Experimental Animals - May 1, 2017 Category: Research Tags: Exp Anim Source Type: research
The hot-water extract of leaves of noni, Morinda citrifolia, promotes the immunocompetence of giant freshwater prawn, Macrobrachium rosenbergii
Publication date: May 2017 Source:Fish & Shellfish Immunology, Volume 64 Author(s): Atika Marisa Halim, Pai-Po Lee, Zhong-Wen Chang, Chin-Chyuan Chang The hot-water Morinda citrifolia leaf extract (HMLE) was prepared for in vitro assessment on phenoloxidase (PO) activity, respiratory bursts (RBs), and phagocytic activity (PA). Furthermore, the HMLE was administrated in the diet at 0.6, 3, and 6 g (kg diet)−1 for Macrobrachium rosenbergii, and the potential effects on the immunocompetence of prawns were evaluated. PO activity, RBs, and PA in hemocytes incubated with the HMLE at 140, 20, 20, and 140 mg l...
Source: Fish and Shellfish Immunology - April 1, 2017 Category: Biology Source Type: research
Effects of short-term consumption of Morinda citrifolia (Noni) fruit juice on mice intestine, liver and kidney immune modulation
. (Source: Food and Agricultural Immunology)
Source: Food and Agricultural Immunology - March 24, 2017 Category: Food Science Authors: Beatriz Coutinho de Sousa Camila Botelho Miguel Wellington Francisco Rodrigues Juliana Reis Machado Marcos Vinicius da Silva Thiago Alvares da Costa Javier Emilio Lazo-Chica Thatiane do Prado Degasperi Helioswilton Sales-Campos Elizabeth Uber Bucek Carlo Source Type: research
Report of Morinda citrifolia chronic toxicity not applicable to commercial noni juice.
PMID: 28341591 [PubMed - as supplied by publisher] (Source: Regulatory Toxicology and Pharmacology : RTP)
Source: Regulatory Toxicology and Pharmacology : RTP - March 22, 2017 Category: Toxicology Authors: West BJ Tags: Regul Toxicol Pharmacol Source Type: research
