Molecules, Vol. 26, Pages 3298: Effects of Deacetylasperulosidic Acid on Atopic Dermatitis through Modulating Immune Balance and Skin Barrier Function in HaCaT, HMC-1, and EOL-1 Cells
This study aimed to determine the anti-AD effects and mechanisms of DAA on HaCaT, HMC-1, and EOL-1 cells. DAA inhibited the gene expression and secretion of AD-related cytokines and chemokines including interleukin (IL)-1β, IL-4, IL-6, IL-8, IL-25, IL-33, thymic stromal lymphopoietin, tumor necrosis factor-alpha, monocyte chemoattractant protein-1, thymus and activation-regulated chemokine, macrophage-derived chemokine, and regulated upon activation, normal T cell expressed and secreted, in all cells, and inhibited histamine release in HMC-1 cells. DAA controlled mitogen-activated protein kinase phosphorylation levels and...
Source: Molecules - May 30, 2021 Category: Chemistry Authors: Jin Su Oh Geum Su Seong Yong Deok Kim Se Young Choung Tags: Article Source Type: research
New alkaloids from the noni juice with potential α-glucosidase inhibitory activity
Fitoterapia. 2021 May 25:104946. doi: 10.1016/j.fitote.2021.104946. Online ahead of print.ABSTRACTFour new alkaloids, nonialkaloids A-D (1-4) and six known analogues (5-10) were isolated from the noni juice. Among the new compounds, 1 and 2 are indole alkaloids with a seven-membered fused N-heterocyclic ring, 3 and 4 are quaternary ammonium derivatives. The structures were elucidated by extensive NMR and MS analysis, while the absolute configurations of the stereogenic carbons were established based on quantum-chemical electronic circular dichroism calculations or the modified Mosher's method. All the isolates were tested ...
Source: Fitoterapia - May 28, 2021 Category: Biochemistry Authors: Bin Zhang Zhang-Xin Yu Xue-Ming Zhou Xu-Hua Nong Xiao-Bao Li Hao Wang Hui Wang Guang-Ying Chen Source Type: research
New alkaloids from the noni juice with potential α-glucosidase inhibitory activity
Fitoterapia. 2021 May 25:104946. doi: 10.1016/j.fitote.2021.104946. Online ahead of print.ABSTRACTFour new alkaloids, nonialkaloids A-D (1-4) and six known analogues (5-10) were isolated from the noni juice. Among the new compounds, 1 and 2 are indole alkaloids with a seven-membered fused N-heterocyclic ring, 3 and 4 are quaternary ammonium derivatives. The structures were elucidated by extensive NMR and MS analysis, while the absolute configurations of the stereogenic carbons were established based on quantum-chemical electronic circular dichroism calculations or the modified Mosher's method. All the isolates were tested ...
Source: Fitoterapia - May 28, 2021 Category: Biochemistry Authors: Bin Zhang Zhang-Xin Yu Xue-Ming Zhou Xu-Hua Nong Xiao-Bao Li Hao Wang Hui Wang Guang-Ying Chen Source Type: research
New alkaloids from the noni juice with potential α-glucosidase inhibitory activity
Fitoterapia. 2021 May 25:104946. doi: 10.1016/j.fitote.2021.104946. Online ahead of print.ABSTRACTFour new alkaloids, nonialkaloids A-D (1-4) and six known analogues (5-10) were isolated from the noni juice. Among the new compounds, 1 and 2 are indole alkaloids with a seven-membered fused N-heterocyclic ring, 3 and 4 are quaternary ammonium derivatives. The structures were elucidated by extensive NMR and MS analysis, while the absolute configurations of the stereogenic carbons were established based on quantum-chemical electronic circular dichroism calculations or the modified Mosher's method. All the isolates were tested ...
Source: Fitoterapia - May 28, 2021 Category: Biochemistry Authors: Bin Zhang Zhang-Xin Yu Xue-Ming Zhou Xu-Hua Nong Xiao-Bao Li Hao Wang Hui Wang Guang-Ying Chen Source Type: research
New alkaloids from the noni juice with potential α-glucosidase inhibitory activity
Fitoterapia. 2021 May 25:104946. doi: 10.1016/j.fitote.2021.104946. Online ahead of print.ABSTRACTFour new alkaloids, nonialkaloids A-D (1-4) and six known analogues (5-10) were isolated from the noni juice. Among the new compounds, 1 and 2 are indole alkaloids with a seven-membered fused N-heterocyclic ring, 3 and 4 are quaternary ammonium derivatives. The structures were elucidated by extensive NMR and MS analysis, while the absolute configurations of the stereogenic carbons were established based on quantum-chemical electronic circular dichroism calculations or the modified Mosher's method. All the isolates were tested ...
Source: Fitoterapia - May 28, 2021 Category: Biochemistry Authors: Bin Zhang Zhang-Xin Yu Xue-Ming Zhou Xu-Hua Nong Xiao-Bao Li Hao Wang Hui Wang Guang-Ying Chen Source Type: research
New alkaloids from the noni juice with potential α-glucosidase inhibitory activity
Fitoterapia. 2021 May 25:104946. doi: 10.1016/j.fitote.2021.104946. Online ahead of print.ABSTRACTFour new alkaloids, nonialkaloids A-D (1-4) and six known analogues (5-10) were isolated from the noni juice. Among the new compounds, 1 and 2 are indole alkaloids with a seven-membered fused N-heterocyclic ring, 3 and 4 are quaternary ammonium derivatives. The structures were elucidated by extensive NMR and MS analysis, while the absolute configurations of the stereogenic carbons were established based on quantum-chemical electronic circular dichroism calculations or the modified Mosher's method. All the isolates were tested ...
Source: Fitoterapia - May 28, 2021 Category: Biochemistry Authors: Bin Zhang Zhang-Xin Yu Xue-Ming Zhou Xu-Hua Nong Xiao-Bao Li Hao Wang Hui Wang Guang-Ying Chen Source Type: research
New alkaloids from the noni juice with potential α-glucosidase inhibitory activity
Fitoterapia. 2021 May 25:104946. doi: 10.1016/j.fitote.2021.104946. Online ahead of print.ABSTRACTFour new alkaloids, nonialkaloids A-D (1-4) and six known analogues (5-10) were isolated from the noni juice. Among the new compounds, 1 and 2 are indole alkaloids with a seven-membered fused N-heterocyclic ring, 3 and 4 are quaternary ammonium derivatives. The structures were elucidated by extensive NMR and MS analysis, while the absolute configurations of the stereogenic carbons were established based on quantum-chemical electronic circular dichroism calculations or the modified Mosher's method. All the isolates were tested ...
Source: Fitoterapia - May 28, 2021 Category: Biochemistry Authors: Bin Zhang Zhang-Xin Yu Xue-Ming Zhou Xu-Hua Nong Xiao-Bao Li Hao Wang Hui Wang Guang-Ying Chen Source Type: research
Molecules, Vol. 26, Pages 2604: Changes in Phenols, Polysaccharides and Volatile Profiles of Noni (Morinda citrifolia L.) Juice during Fermentation
Li
Wu Li
The change in phenols, polysaccharides and volatile profiles of noni juice from laboratory- and factory-scale fermentation was analyzed during a 63-day fermentation process. The phenol and polysaccharide contents and aroma characteristics clearly changed according to fermentation scale and time conditions. The flavonoid content in noni juice gradually increased with fermentation. Seventy-three volatile compounds were identified by solid-phase microextraction coupled with gas chromatography–mass spectrometry (SPME-GC-MS). Methyl hexanoate, 3-methyl-3-buten-1-ol, octanoic acid, hexanoic acid and 2-heptanone...
Source: Molecules - April 29, 2021 Category: Chemistry Authors: Zhulin Wang Rong Dou Ruili Yang Kun Cai Congfa Li Wu Li Tags: Article Source Type: research
Correction to: Mosquito Repellent and Antibacterial Efficiency of Facile and Low ‑Cost Silver Nanoparticles Synthesized Using the Leaf Extract of Morinda Citrifolia
A correction to this paper has been published:https://doi.org/10.1007/s11468-021-01439-0 (Source: Plasmonics)
Source: Plasmonics - April 7, 2021 Category: Biomedical Science Source Type: research
A review on functional and nutritional properties of noni fruit seed (Morinda citrifolia L.) and its oil
Publication date: June 2021Source: Food Bioscience, Volume 41Author(s): M.H.A. Jahurul, M. Patricia, A. Shihabul, M.R. Norazlina, M.R. Ramlah George, A.W. Noorakmar, J.S. Lee, R. Jumardi, S. Jinap, I.S.M. Zaidul (Source: Food Bioscience)
Source: Food Bioscience - March 31, 2021 Category: Food Science Source Type: research
Evaluation of Morinda citrifolia (noni) fruit extract as a bone regenerative material in the treatment of periodontal intrabony osseous defects: Clinical and cone-beam computed tomography assessment
Conclusions: The use of M. citrifolia fruit extract in the intraosseous defect was found to be efficacious in terms of relative attachment level and the amount of bone fill, and it had shown some anti-inflammatory affect. (Source: Journal of Indian Society of Periodontology)
Source: Journal of Indian Society of Periodontology - March 1, 2021 Category: Dentistry Authors: Blessy Shin Sabu Kabbur Thippanna Chandrashekar Rohit Mishra Vandana Dubey Tripathi Honey Khatri Ankita Deo Source Type: research
Evaluation of Push-out Bond Strength of a Resin Sealer to Dentin after a Final Flush of Three Irrigants
CONCLUSION: Chitosan and MCJ can be used as alternative irrigants as a final flush during the cleaning and shaping of the root canals.CLINICAL SIGNIFICANCE: EDTA, chitosan solution, and MCJ are efficient in smear layer removal which thereby increases better sealer penetration and prevents the dislocation of obturating materials.PMID:33568582 (Source: J Contemp Dent Pract)
Source: J Contemp Dent Pract - February 11, 2021 Category: Dentistry Authors: Shubha Choudhury Sunita Shivanand Anand C Patil Sneha A Patil Preeti K Doddwad Chetan Patil Source Type: research
Evaluation of Push-out Bond Strength of a Resin Sealer to Dentin after a Final Flush of Three Irrigants
CONCLUSION: Chitosan and MCJ can be used as alternative irrigants as a final flush during the cleaning and shaping of the root canals.CLINICAL SIGNIFICANCE: EDTA, chitosan solution, and MCJ are efficient in smear layer removal which thereby increases better sealer penetration and prevents the dislocation of obturating materials.PMID:33568582 (Source: J Contemp Dent Pract)
Source: J Contemp Dent Pract - February 11, 2021 Category: Dentistry Authors: Shubha Choudhury Sunita Shivanand Anand C Patil Sneha A Patil Preeti K Doddwad Chetan Patil Source Type: research
Evaluation of Push-out Bond Strength of a Resin Sealer to Dentin after a Final Flush of Three Irrigants
CONCLUSION: Chitosan and MCJ can be used as alternative irrigants as a final flush during the cleaning and shaping of the root canals.CLINICAL SIGNIFICANCE: EDTA, chitosan solution, and MCJ are efficient in smear layer removal which thereby increases better sealer penetration and prevents the dislocation of obturating materials.PMID:33568582 (Source: J Contemp Dent Pract)
Source: J Contemp Dent Pract - February 11, 2021 Category: Dentistry Authors: Shubha Choudhury Sunita Shivanand Anand C Patil Sneha A Patil Preeti K Doddwad Chetan Patil Source Type: research
Evaluation of Push-out Bond Strength of a Resin Sealer to Dentin after a Final Flush of Three Irrigants
CONCLUSION: Chitosan and MCJ can be used as alternative irrigants as a final flush during the cleaning and shaping of the root canals.CLINICAL SIGNIFICANCE: EDTA, chitosan solution, and MCJ are efficient in smear layer removal which thereby increases better sealer penetration and prevents the dislocation of obturating materials.PMID:33568582 (Source: J Contemp Dent Pract)
Source: J Contemp Dent Pract - February 11, 2021 Category: Dentistry Authors: Shubha Choudhury Sunita Shivanand Anand C Patil Sneha A Patil Preeti K Doddwad Chetan Patil Source Type: research
