GSE233289 RNA-seq analysis of peripheral nerve in Mtmr2 null model of CMT4B1.
Contributors : Shuang Liu ; Phu Duong ; John Svaren ; Alessandra BolinoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe goal of the experiment was to assess gene expression in sciatic nerve of Mtmr2 null mice, which is a model of the genetic neuropathy known as CMT4B1, and response to niacin treatment. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - January 1, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research

Nutrition fact label (NFL) use is related to meeting the requirements for vitamins and minerals not listed on NFLs: Data from the Korea National Health and Nutritional Examination Survey VIII (2019 –2021) for the prepandemic and pandemic periods
by Jung Min Cho The credibility and wide usability of nutrition fact labels (NFLs) have increased due to the pandemic, which may lead to healthier nutritional choices. This cross-sectional study aimed to evaluate the association between NFL use and meeting the estimated average requirements (EARs) for vitamins an d minerals not listed on NFLs during the prepandemic (2019,n = 6606) and pandemic periods (2020 and 2021,n = 12085) using KNHANES data. Household surveys, health behavior interviews, and health checkup examinations were conducted for all participants. Subjects were included in the unAware+noUse, Aware+noUse, and ...
Source: PLoS One - December 28, 2023 Category: Biomedical Science Authors: Jung Min Cho Source Type: research

Lipoprotein (a) as a Biomarker for Cardiovascular Diseases and Potential New Therapies to Mitigate Risk
CONCLUSION: Several emerging treatments with robust Lp(a)-lowering effects may significantly lower atherosclerotic cardiovascular risk.PMID:38141196 | DOI:10.2174/0115701611267835231210054909 (Source: Atherosclerosis)
Source: Atherosclerosis - December 23, 2023 Category: Cardiology Authors: Debabrata Mukherjee Steven E Nissen Source Type: research

Lipoprotein (a) as a Biomarker for Cardiovascular Diseases and Potential New Therapies to Mitigate Risk
CONCLUSION: Several emerging treatments with robust Lp(a)-lowering effects may significantly lower atherosclerotic cardiovascular risk.PMID:38141196 | DOI:10.2174/0115701611267835231210054909 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - December 23, 2023 Category: Drugs & Pharmacology Authors: Debabrata Mukherjee Steven E Nissen Source Type: research

Lipoprotein (a) as a Biomarker for Cardiovascular Diseases and Potential New Therapies to Mitigate Risk
CONCLUSION: Several emerging treatments with robust Lp(a)-lowering effects may significantly lower atherosclerotic cardiovascular risk.PMID:38141196 | DOI:10.2174/0115701611267835231210054909 (Source: Atherosclerosis)
Source: Atherosclerosis - December 23, 2023 Category: Cardiology Authors: Debabrata Mukherjee Steven E Nissen Source Type: research

Lipoprotein (a) as a Biomarker for Cardiovascular Diseases and Potential New Therapies to Mitigate Risk
CONCLUSION: Several emerging treatments with robust Lp(a)-lowering effects may significantly lower atherosclerotic cardiovascular risk.PMID:38141196 | DOI:10.2174/0115701611267835231210054909 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - December 23, 2023 Category: Drugs & Pharmacology Authors: Debabrata Mukherjee Steven E Nissen Source Type: research

Lipoprotein (a) as a Biomarker for Cardiovascular Diseases and Potential New Therapies to Mitigate Risk
CONCLUSION: Several emerging treatments with robust Lp(a)-lowering effects may significantly lower atherosclerotic cardiovascular risk.PMID:38141196 | DOI:10.2174/0115701611267835231210054909 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - December 23, 2023 Category: Drugs & Pharmacology Authors: Debabrata Mukherjee Steven E Nissen Source Type: research

Lipoprotein (a) as a Biomarker for Cardiovascular Diseases and Potential New Therapies to Mitigate Risk
CONCLUSION: Several emerging treatments with robust Lp(a)-lowering effects may significantly lower atherosclerotic cardiovascular risk.PMID:38141196 | DOI:10.2174/0115701611267835231210054909 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - December 23, 2023 Category: Drugs & Pharmacology Authors: Debabrata Mukherjee Steven E Nissen Source Type: research

Preparation of potential organic fertilizer rich in γ-polyglutamic acid via microbial fermentation using brewer's spent grain as basic substrate
Bioresour Technol. 2023 Dec 18:130216. doi: 10.1016/j.biortech.2023.130216. Online ahead of print.ABSTRACTBrewer's spent grain (BSG) is a main byproduct of the beer industry. BSG is rich in a variety of nutrients, and the search for its effective, high-value utilization is ongoing. Environmental probiotic factor γ-PGA was produced by fermenting Bacillus subtilis with BSG substrate and the fermenting grain components were analyzed. The γ-PGA yield reached 31.58 ± 0.21 g/kg of BSG. Gas chromatography-mass spectrometry and non-targeted metabolomics analyses revealed 73 new volatile substances in the fermenting grains. Furt...
Source: Bioresource Technology - December 20, 2023 Category: Biotechnology Authors: Fengqing Wang Yanmei Chen Jia Zheng Can Yang Li Li Rong Li Meilin Shi Zhongxuan Li Source Type: research

Preparation of potential organic fertilizer rich in γ-polyglutamic acid via microbial fermentation using brewer's spent grain as basic substrate
Bioresour Technol. 2023 Dec 18:130216. doi: 10.1016/j.biortech.2023.130216. Online ahead of print.ABSTRACTBrewer's spent grain (BSG) is a main byproduct of the beer industry. BSG is rich in a variety of nutrients, and the search for its effective, high-value utilization is ongoing. Environmental probiotic factor γ-PGA was produced by fermenting Bacillus subtilis with BSG substrate and the fermenting grain components were analyzed. The γ-PGA yield reached 31.58 ± 0.21 g/kg of BSG. Gas chromatography-mass spectrometry and non-targeted metabolomics analyses revealed 73 new volatile substances in the fermenting grains. Furt...
Source: Bioresource Technology - December 20, 2023 Category: Biotechnology Authors: Fengqing Wang Yanmei Chen Jia Zheng Can Yang Li Li Rong Li Meilin Shi Zhongxuan Li Source Type: research

Effects of Niacin on apolipoprotein A1 and B levels: A systematic review and meta-analysis of Randomised Controlled Trials
Br J Nutr. 2023 Dec 19:1-27. doi: 10.1017/S000711452300288X. Online ahead of print.ABSTRACTNiacin has been investigated for its potential impact on lipid metabolism and cardiovascular health. This meta-analysis aims to systematically evaluate the effects of Niacin interventions on apolipoprotein A1 (Apo A1) and apolipoprotein B (Apo B) levels, key regulators of lipoprotein metabolism and markers of cardiovascular risk. A comprehensive search of the literature was performed on five databases of PubMed, Scopus, Web of Science, Embase and Cochrane library, from inception up to 15 July 2023. This search identified 1452 publica...
Source: The British Journal of Nutrition - December 19, 2023 Category: Nutrition Authors: Somayeh Saboori Esmaeil Yousefi Rad Jonathan Tammam Pariyarath Sangeetha Thondre Shelly Coe Source Type: research

Niacin treatment prevents bone loss in iron overload osteoporotic rats via activation of SIRT1 signaling pathway
Chem Biol Interact. 2023 Dec 9:110827. doi: 10.1016/j.cbi.2023.110827. Online ahead of print.ABSTRACTRecently, more and more studies have revealed that iron overload can lead to osteoporosis by inducing oxidative stress. Niacin (NAN), also known as nicotinate or vitamin B3, has been confirmed to possess potent antioxidative effects. In addition, very little is currently known about the protective effects of NAN on iron overload in osteoporotic bone tissue. Therefore, we aimed to evaluate the protective effect of niacin on iron overload-induced bone injury and to investigate the effect and underlying mechanisms of the niaci...
Source: Chemico-Biological Interactions - December 11, 2023 Category: Molecular Biology Authors: Zhou-Shan Tao Mao-Sheng Zhou Xing-Jing Wu Source Type: research

Niacin treatment prevents bone loss in iron overload osteoporotic rats via activation of SIRT1 signaling pathway
Chem Biol Interact. 2023 Dec 9:110827. doi: 10.1016/j.cbi.2023.110827. Online ahead of print.ABSTRACTRecently, more and more studies have revealed that iron overload can lead to osteoporosis by inducing oxidative stress. Niacin (NAN), also known as nicotinate or vitamin B3, has been confirmed to possess potent antioxidative effects. In addition, very little is currently known about the protective effects of NAN on iron overload in osteoporotic bone tissue. Therefore, we aimed to evaluate the protective effect of niacin on iron overload-induced bone injury and to investigate the effect and underlying mechanisms of the niaci...
Source: Chemico-Biological Interactions - December 11, 2023 Category: Molecular Biology Authors: Zhou-Shan Tao Mao-Sheng Zhou Xing-Jing Wu Source Type: research

Niacin treatment prevents bone loss in iron overload osteoporotic rats via activation of SIRT1 signaling pathway
Chem Biol Interact. 2023 Dec 9:110827. doi: 10.1016/j.cbi.2023.110827. Online ahead of print.ABSTRACTRecently, more and more studies have revealed that iron overload can lead to osteoporosis by inducing oxidative stress. Niacin (NAN), also known as nicotinate or vitamin B3, has been confirmed to possess potent antioxidative effects. In addition, very little is currently known about the protective effects of NAN on iron overload in osteoporotic bone tissue. Therefore, we aimed to evaluate the protective effect of niacin on iron overload-induced bone injury and to investigate the effect and underlying mechanisms of the niaci...
Source: Chemico-Biological Interactions - December 11, 2023 Category: Molecular Biology Authors: Zhou-Shan Tao Mao-Sheng Zhou Xing-Jing Wu Source Type: research

Niacin treatment prevents bone loss in iron overload osteoporotic rats via activation of SIRT1 signaling pathway
Chem Biol Interact. 2023 Dec 9:110827. doi: 10.1016/j.cbi.2023.110827. Online ahead of print.ABSTRACTRecently, more and more studies have revealed that iron overload can lead to osteoporosis by inducing oxidative stress. Niacin (NAN), also known as nicotinate or vitamin B3, has been confirmed to possess potent antioxidative effects. In addition, very little is currently known about the protective effects of NAN on iron overload in osteoporotic bone tissue. Therefore, we aimed to evaluate the protective effect of niacin on iron overload-induced bone injury and to investigate the effect and underlying mechanisms of the niaci...
Source: Chemico-Biological Interactions - December 11, 2023 Category: Molecular Biology Authors: Zhou-Shan Tao Mao-Sheng Zhou Xing-Jing Wu Source Type: research