Diagnostic value of niacin skin blunting response in adolescent patients with depression
To investigate the differences in the niacin skin flushing response of adolescent depressed patients and healthy adolescents and its diagnostic value in adolescent depression. (Source: BMC Psychiatry)
Source: BMC Psychiatry - November 8, 2023 Category: Psychiatry Authors: Shen Nianhong, Liu Pan, Li Caijun, Ye Hongying, Sun You, Chang Jie, Zhou Jinquan, Zhou Yunshan, Wang Donghu, Yu Mingchao, Huang Chengbing and Hou Xueyuan Tags: Research Source Type: research
Impact of Bifidobacterium longum BB536 on nausea caused by pirfenidone in a mouse model of pellagra
Conclusions: The utility of BB536 in pirfenidone-related pellagra from the viewpoint of reducing AEs was indicated. Importantly, further research is needed prior to clinical use of BB536 because its safety has not yet been evaluated in patients with IPF. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Kuronuma, K., Susai, N., Yoshioka, T., Saito, A., Chiba, H. Tags: Idiopathic interstitial pneumonias Source Type: research
Low micronutrient intake in nursing home residents, a cross-sectional study
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. Low intake of micronutrients is associated with health-related problems in nursing home residents. As their food intake is generally low, it is expected that their micronutrient intake will be low as well. The nutrient intake of 189 residents (mean age 85.0 years (SD: 7.4)) in five different Dutch nursing homes was measured based on 3-day direct observations of intake. Micronutrient intake, without supplementation, was calculated using the Dutch food composition table, and SPADE software was used to model habitual intake. Intake was compared to the estimated av...
Source: Applied Physiology, Nutrition, and Metabolism - October 27, 2023 Category: Physiology Authors: J.W. Borkent M. Manders A. Nijhof E. Naumann E.J.M. Feskens M.A.E. de van der Schueren Source Type: research
Tragacanth gum-based nano-nutraceuticals synthesis by encapsulation of beetroot juice and Ocimum basilicum leaves for micronutrient deficient population
Int J Biol Macromol. 2023 Oct 18:127502. doi: 10.1016/j.ijbiomac.2023.127502. Online ahead of print.ABSTRACTMicronutrient deficiencies, such as iron, folic acid, and vitamins C and D, are currently prevalent due to inadequate consumption of natural food sources, namely raw vegetables and fruits. This deficiency is compounded by the growing reliance on synthetic nutraceuticals and processed food, which exhibit poor absorbency within the gastrointestinal tract. Scientific studies consistently indicate that naturally prepared whole foods are superior in terms of nutrient absorption compared to processed and synthetic suppleme...
Source: International Journal of Biological Macromolecules - October 20, 2023 Category: Biochemistry Authors: Dravin Pratap Singh P Gopinath Source Type: research
Analysis of Metformin, Niacinamide, and Niacin as Skin Cancer Preventative Medications in Solid Organ Transplant Recipients
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - October 18, 2023 Category: Dermatology Authors: Courtney Linkous, Nicholas Strat, Chelsea Shope, Laura Andrews, Lara Wine Lee Source Type: research
Oxidized phospholipids in cardiovascular disease
Nat Rev Cardiol. 2023 Oct 17. doi: 10.1038/s41569-023-00937-4. Online ahead of print.ABSTRACTProlonged or excessive exposure to oxidized phospholipids (OxPLs) generates chronic inflammation. OxPLs are present in atherosclerotic lesions and can be detected in plasma on apolipoprotein B (apoB)-containing lipoproteins. When initially conceptualized, OxPL-apoB measurement in plasma was expected to reflect the concentration of minimally oxidized LDL, but, surprisingly, it correlated more strongly with plasma lipoprotein(a) (Lp(a)) levels. Indeed, experimental and clinical studies show that Lp(a) particles carry the largest frac...
Source: Atherosclerosis - October 17, 2023 Category: Cardiology Authors: Sotirios Tsimikas Joseph L Witztum Source Type: research
Lipid-lowering therapies for cardiovascular disease prevention and management in primary care: PEER umbrella systematic review of systematic reviews
CONCLUSION: Statins have the most consistent evidence for the prevention of cardiovascular complications with a relative risk reduction of about 25% for MACE and 10% to 15% for mortality. The addition of ezetimibe, a PCSK9 inhibitor, or eicosapentaenoic acid ethyl ester to a statin provides additional MACE risk reduction but has no effect on all-cause mortality.PMID:37833094 | DOI:10.46747/cfp.6910701 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - October 13, 2023 Category: Primary Care Authors: Nicolas Dugr é Adrienne J Lindblad Danielle Perry G Michael Allan Émélie Braschi Jamie Falk Liesbeth Froentjes Scott R Garrison Jessica E M Kirkwood Christina S Korownyk James P McCormack Samantha S Moe Allison Paige Jen Potter Betsy S Thomas Joey Ton Source Type: research
PEER simplified lipid guideline 2023 update: Prevention and management of cardiovascular disease in primary care
CONCLUSION: These updated evidence-based guidelines provide a simplified approach to lipid management for the prevention and management of CVD. These guidelines were created by and for primary health care professionals and their patients.PMID:37833089 | DOI:10.46747/cfp.6910675 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - October 13, 2023 Category: Primary Care Authors: Michael R Kolber Scott Klarenbach Michel Cauchon Mike Cotterill Loren Regier Raelene D Marceau Norah Duggan Rebecca Whitley Alex S Halme Tanis Poshtar G Michael Allan Christina S Korownyk Joey Ton Liesbeth Froentjes Samantha S Moe Danielle Perry Betsy S T Source Type: research
