Myositis
induced by immune checkpoint inhibitors (ICIs) is an infrequent, potentially fatal, immune-related adverse event. It has higher incidence in patients who receive combination ICI therapy compared to monotherapy. Patients can present with clinical manifestation symptoms of myositis alone or in combination with myocarditis and/or myasthenia gravis, which significantly worsens the course and prognosis. Diagnosis can generally be made on the basis of clinical presentation, elevation of muscle enzymes, and electromyographic changes, but some patients may require a muscle biopsy. The first line of therapy is high-dose corticoste...
Source: Rheumatic Disease Clinics of North America - March 12, 2024 Category: Rheumatology Authors: Athira Jayan, Andrew L. Mammen, Maria E. Suarez-Almazor Source Type: research
COLQ-Congenital myasthenic syndrome in an Iranian cohort: the clinical and genetics spectrum
Congenital myasthenic syndrome (CMS) is a group of neuromuscular disorders caused by abnormal signal transmission at the motor endplate. Mutations in the collagen-like tail subunit gene (COLQ) of acetylcholineste... (Source: Orphanet Journal of Rare Diseases)
Source: Orphanet Journal of Rare Diseases - March 12, 2024 Category: Internal Medicine Authors: Omid Hesami, Mahtab Ramezani, Aida Ghasemi, Farzad Fatehi, Ali Asghar Okhovat, Bentolhoda Ziaadini, Ariana Kariminejad and Shahriar Nafissi Tags: Research Source Type: research
Immune Checkpoint Inhibitor-induced Myositis
Myositis induced by immune checkpoint inhibitors (ICIs) is an infrequent, potentially fatal, immune-related adverse event. It has higher incidence in patients who receive combination ICI therapy compared to monotherapy. Patients can present with clinical manifestation symptoms of myositis alone or in combination with myocarditis and/or myasthenia gravis, which significantly worsens the course and prognosis. Diagnosis can generally be made on the basis of clinical presentation, elevation of muscle enzymes, and electromyographic changes, but some patients may require a muscle biopsy. The first line of therapy is high-dose co...
Source: Rheumatic Disease Clinics of North America - March 12, 2024 Category: Rheumatology Authors: Athira Jayan, Andrew L. Mammen, Maria E. Suarez-Almazor Source Type: research
Current state of research on exercise for the treatment of myasthenia gravis: A scoping review
CONCLUSION: This scoping review provides an overview of the evidence concerning exercise treatment for MG. Key gaps in evidence include a limited number of participants, complex interventions, variability in outcome selection, and insufficient reporting in publications. The promotion of exercise treatment for MG still encounters several obstacles. A larger population, rigorous study design and conduction, standardized interventions and outcomes, and standardized reporting are essential.PMID:38458542 | DOI:10.1016/j.ctim.2024.103033 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 8, 2024 Category: Complementary Medicine Authors: Siyang Peng Linghao Meng Ruiying Fang Qiqi Shen Yukun Tian Anni Xiong Shaohong Li Yajing Yang Weiqian Chang Jinxia Ni Wenzeng Zhu Source Type: research
Current state of research on exercise for the treatment of myasthenia gravis: A scoping review
CONCLUSION: This scoping review provides an overview of the evidence concerning exercise treatment for MG. Key gaps in evidence include a limited number of participants, complex interventions, variability in outcome selection, and insufficient reporting in publications. The promotion of exercise treatment for MG still encounters several obstacles. A larger population, rigorous study design and conduction, standardized interventions and outcomes, and standardized reporting are essential.PMID:38458542 | DOI:10.1016/j.ctim.2024.103033 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 8, 2024 Category: Complementary Medicine Authors: Siyang Peng Linghao Meng Ruiying Fang Qiqi Shen Yukun Tian Anni Xiong Shaohong Li Yajing Yang Weiqian Chang Jinxia Ni Wenzeng Zhu Source Type: research
Current state of research on exercise for the treatment of myasthenia gravis: A scoping review
CONCLUSION: This scoping review provides an overview of the evidence concerning exercise treatment for MG. Key gaps in evidence include a limited number of participants, complex interventions, variability in outcome selection, and insufficient reporting in publications. The promotion of exercise treatment for MG still encounters several obstacles. A larger population, rigorous study design and conduction, standardized interventions and outcomes, and standardized reporting are essential.PMID:38458542 | DOI:10.1016/j.ctim.2024.103033 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 8, 2024 Category: Complementary Medicine Authors: Siyang Peng Linghao Meng Ruiying Fang Qiqi Shen Yukun Tian Anni Xiong Shaohong Li Yajing Yang Weiqian Chang Jinxia Ni Wenzeng Zhu Source Type: research
Current state of research on exercise for the treatment of myasthenia gravis: A scoping review
CONCLUSION: This scoping review provides an overview of the evidence concerning exercise treatment for MG. Key gaps in evidence include a limited number of participants, complex interventions, variability in outcome selection, and insufficient reporting in publications. The promotion of exercise treatment for MG still encounters several obstacles. A larger population, rigorous study design and conduction, standardized interventions and outcomes, and standardized reporting are essential.PMID:38458542 | DOI:10.1016/j.ctim.2024.103033 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 8, 2024 Category: Complementary Medicine Authors: Siyang Peng Linghao Meng Ruiying Fang Qiqi Shen Yukun Tian Anni Xiong Shaohong Li Yajing Yang Weiqian Chang Jinxia Ni Wenzeng Zhu Source Type: research
Current state of research on exercise for the treatment of myasthenia gravis: A scoping review
CONCLUSION: This scoping review provides an overview of the evidence concerning exercise treatment for MG. Key gaps in evidence include a limited number of participants, complex interventions, variability in outcome selection, and insufficient reporting in publications. The promotion of exercise treatment for MG still encounters several obstacles. A larger population, rigorous study design and conduction, standardized interventions and outcomes, and standardized reporting are essential.PMID:38458542 | DOI:10.1016/j.ctim.2024.103033 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 8, 2024 Category: Complementary Medicine Authors: Siyang Peng Linghao Meng Ruiying Fang Qiqi Shen Yukun Tian Anni Xiong Shaohong Li Yajing Yang Weiqian Chang Jinxia Ni Wenzeng Zhu Source Type: research
Current state of research on exercise for the treatment of myasthenia gravis: A scoping review
CONCLUSION: This scoping review provides an overview of the evidence concerning exercise treatment for MG. Key gaps in evidence include a limited number of participants, complex interventions, variability in outcome selection, and insufficient reporting in publications. The promotion of exercise treatment for MG still encounters several obstacles. A larger population, rigorous study design and conduction, standardized interventions and outcomes, and standardized reporting are essential.PMID:38458542 | DOI:10.1016/j.ctim.2024.103033 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 8, 2024 Category: Complementary Medicine Authors: Siyang Peng Linghao Meng Ruiying Fang Qiqi Shen Yukun Tian Anni Xiong Shaohong Li Yajing Yang Weiqian Chang Jinxia Ni Wenzeng Zhu Source Type: research
Current state of research on exercise for the treatment of myasthenia gravis: A scoping review
CONCLUSION: This scoping review provides an overview of the evidence concerning exercise treatment for MG. Key gaps in evidence include a limited number of participants, complex interventions, variability in outcome selection, and insufficient reporting in publications. The promotion of exercise treatment for MG still encounters several obstacles. A larger population, rigorous study design and conduction, standardized interventions and outcomes, and standardized reporting are essential.PMID:38458542 | DOI:10.1016/j.ctim.2024.103033 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 8, 2024 Category: Complementary Medicine Authors: Siyang Peng Linghao Meng Ruiying Fang Qiqi Shen Yukun Tian Anni Xiong Shaohong Li Yajing Yang Weiqian Chang Jinxia Ni Wenzeng Zhu Source Type: research
Current state of research on exercise for the treatment of myasthenia gravis: A scoping review
CONCLUSION: This scoping review provides an overview of the evidence concerning exercise treatment for MG. Key gaps in evidence include a limited number of participants, complex interventions, variability in outcome selection, and insufficient reporting in publications. The promotion of exercise treatment for MG still encounters several obstacles. A larger population, rigorous study design and conduction, standardized interventions and outcomes, and standardized reporting are essential.PMID:38458542 | DOI:10.1016/j.ctim.2024.103033 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 8, 2024 Category: Complementary Medicine Authors: Siyang Peng Linghao Meng Ruiying Fang Qiqi Shen Yukun Tian Anni Xiong Shaohong Li Yajing Yang Weiqian Chang Jinxia Ni Wenzeng Zhu Source Type: research
Current state of research on exercise for the treatment of myasthenia gravis: A scoping review
CONCLUSION: This scoping review provides an overview of the evidence concerning exercise treatment for MG. Key gaps in evidence include a limited number of participants, complex interventions, variability in outcome selection, and insufficient reporting in publications. The promotion of exercise treatment for MG still encounters several obstacles. A larger population, rigorous study design and conduction, standardized interventions and outcomes, and standardized reporting are essential.PMID:38458542 | DOI:10.1016/j.ctim.2024.103033 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 8, 2024 Category: Complementary Medicine Authors: Siyang Peng Linghao Meng Ruiying Fang Qiqi Shen Yukun Tian Anni Xiong Shaohong Li Yajing Yang Weiqian Chang Jinxia Ni Wenzeng Zhu Source Type: research
The modified Lyon ’s position: an alternative approach to robotic thymectomy
This report proposes an innovative approach to robotic thymectomy for patients diagnosed with thymoma or thymic hyperplasia associated with myasthenia gravis. (Source: Journal of Robotic Surgery)
Source: Journal of Robotic Surgery - March 5, 2024 Category: Surgery Source Type: research
Cancers, Vol. 16, Pages 1040: The Way Ahead: Lessons Learned from Decades of Cancer Research on Thymomas and Thymic Carcinomas
rx
The history of thymoma (TH) research begins in the early 20th century, when Bell first recognized the epithelial nature of these tumors and their association with myasthenia gravis (MG) [...] (Source: Cancers)
Source: Cancers - March 4, 2024 Category: Cancer & Oncology Authors: Philipp Str öbel Alexander Marx Tags: Editorial Source Type: research
Batoclimab vs Placebo for Generalized Myasthenia Gravis
This randomized clinical trial investigates the effectiveness and safety of the neonatal fragment crystallizable receptor monoclonal antibody, batoclimab, in adults with generalized myasthenia gravis. (Source: JAMA Neurology)
Source: JAMA Neurology - March 4, 2024 Category: Neurology Source Type: research
