Omalizumab-induced ocular myasthenia gravis?
Can J Ophthalmol. 2024 Apr 14:S0008-4182(24)00100-5. doi: 10.1016/j.jcjo.2024.03.018. Online ahead of print.NO ABSTRACTPMID:38631494 | DOI:10.1016/j.jcjo.2024.03.018 (Source: Canadian Journal of Ophthalmology)
Source: Canadian Journal of Ophthalmology - April 17, 2024 Category: Opthalmology Authors: Hanru Wang Devaraj Supramaniam Sudha Cugati Celia Chen Source Type: research
Construction of ceRNA network mediated by circRNAs screening from microarray and identification of novel biomarkers for myasthenia gravis
CONCLUSIONS: We found that circFRMD4, circPIGB and circNUP214 can be considered as valuable potential novel biomarkers for AchR + MG. CircFRMD4 participate in the development of AchR + MG via targeting binding with miR-145-5p.PMID:38631652 | DOI:10.1016/j.gene.2024.148463 (Source: Gene)
Source: Gene - April 17, 2024 Category: Genetics & Stem Cells Authors: Xiaotong Kong Tao Wu Hanlu Cai Zhimin Chen Yu Wang Ping He Peifang Liu Lei Li Shanshan Peng Fanfan Xu Jianjian Wang Huixue Zhang Lihua Wang Source Type: research
Similar metabolic pathways are affected in both Congenital Myasthenic Syndrome-22 and Prader-Willi Syndrome
In conclusion, we provide the first molecular parallels between CMS22 and PWS, raising the possibility that PREPL substrates might become therapeutic targets for treating both disorders.PMID:38626828 | DOI:10.1016/j.bbadis.2024.167175 (Source: Biochimica et Biophysica Acta)
Source: Biochimica et Biophysica Acta - April 16, 2024 Category: Biochemistry Authors: Kritika Bhalla Karen Rosier Yenthe Monnens Sandra Meulemans Ellen Vervoort Lieven Thorrez Patrizia Agostinis Daniel T Meier Anne Rochtus James L Resnick John W M Creemers Source Type: research
Similar metabolic pathways are affected in both Congenital Myasthenic Syndrome-22 and Prader-Willi Syndrome
In conclusion, we provide the first molecular parallels between CMS22 and PWS, raising the possibility that PREPL substrates might become therapeutic targets for treating both disorders.PMID:38626828 | DOI:10.1016/j.bbadis.2024.167175 (Source: Biochimica et Biophysica Acta)
Source: Biochimica et Biophysica Acta - April 16, 2024 Category: Biochemistry Authors: Kritika Bhalla Karen Rosier Yenthe Monnens Sandra Meulemans Ellen Vervoort Lieven Thorrez Patrizia Agostinis Daniel T Meier Anne Rochtus James L Resnick John W M Creemers Source Type: research
Therapeutic Plasma Exchange in AChR-Ab Positive Generalized Myasthenia Gravis: A Real World Study About Its Early Response
(Source: Journal of Inflammation Research)
Source: Journal of Inflammation Research - April 16, 2024 Category: Allergy & Immunology Tags: Journal of Inflammation Research Source Type: research
Ten-year fracture risk in Japanese patients with myasthenia gravis: A comprehensive assessment using the fracture risk assessment tool
Myasthenia gravis (MG) is an immune disorder that causes muscle weakness with an increasing prevalence, particularly among the elderly in Japan. Glucocorticoid treatment for MG is problematic for bone health because of reduced bone density and increased fracture risk. The fracture risk assessment tool (FRAX ®) can estimate fracture risk, but its applicability in patients with MG remains uncertain. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 16, 2024 Category: Neurology Authors: Shingo Konno, Takafumi Uchi, Hideo Kihara, Hideki Sugimoto Source Type: research
Perspectives of people with myasthenia gravis on physical activity and experience of physical activity advice from health professionals in the Australian context: a qualitative study
CONCLUSION: People with MG have unique barriers and enablers to physical activity engagement that clinicians should consider when providing physical activity behaviour change support to this population.PMID:38613411 | DOI:10.1080/09638288.2024.2338877 (Source: Disability and Rehabilitation)
Source: Disability and Rehabilitation - April 13, 2024 Category: Rehabilitation Authors: Tahlia Alsop Marianna Cassimatis Katrina L Williams Sjaan R Gomersall Source Type: research
Perspectives of people with myasthenia gravis on physical activity and experience of physical activity advice from health professionals in the Australian context: a qualitative study
CONCLUSION: People with MG have unique barriers and enablers to physical activity engagement that clinicians should consider when providing physical activity behaviour change support to this population.PMID:38613411 | DOI:10.1080/09638288.2024.2338877 (Source: Disability and Rehabilitation)
Source: Disability and Rehabilitation - April 13, 2024 Category: Rehabilitation Authors: Tahlia Alsop Marianna Cassimatis Katrina L Williams Sjaan R Gomersall Source Type: research
Serum globulin in children with myasthenia gravis: predicting relapse and prognosis
CONCLUSIONS: Elevated globulin levels in children with MG on admission predicts a high relapse rate and poor long-term therapeutic efficacies.PMID:38602312 | DOI:10.1080/01616412.2024.2340883 (Source: Neurological Research)
Source: Neurological Research - April 11, 2024 Category: Neurology Authors: Zhi Jiang Wenjing Hu Zeshu Ning Liwen Wu Liming Yang Hongmei Liao Bo Chen Jingwen Tang Rong Xu Feng Guo Shulei Liu Source Type: research
Bispecific BCMA/CD19 targeted CAR-T cell therapy forces sustained disappearance of symptoms and anti-acetylcholine receptor antibodies in refractory myasthenia gravis: a case report
(Source: Journal of Neurology)
Source: Journal of Neurology - April 11, 2024 Category: Neurology Source Type: research
Tetramine in Patients with Myasthenia Gravis
Intern Med. 2024 Apr 9. doi: 10.2169/internalmedicine.3627-24. Online ahead of print.NO ABSTRACTPMID:38599857 | DOI:10.2169/internalmedicine.3627-24 (Source: Internal Medicine)
Source: Internal Medicine - April 10, 2024 Category: Internal Medicine Authors: Ken-Ichiro Inoue Source Type: research
Respiratory paralysis in a patient with myasthenia gravis after ingestion of marine carnivorous gastropods: A case report
Intern Med. 2024 Apr 9. doi: 10.2169/internalmedicine.2828-23. Online ahead of print.ABSTRACTThe salivary glands of marine carnivorous gastropods contain tetramines, which usually cause mild symptoms of poisoning. However, these symptoms may be fatal in rare cases. A 58-year-old woman with a history of myasthenia gravis complained of dyspnea after consuming marine carnivorous gastropods with intact salivary glands. Upon arrival at the hospital, her blood gas analysis revealed type II respiratory failure with a pCO2 of 154 mmHg. Tracheal intubation was immediately performed. Her respiratory condition improved the following ...
Source: Internal Medicine - April 10, 2024 Category: Internal Medicine Authors: Kenji Inoue Masatsugu Hasegawa Ryosuke Sato Michio Kobayashi Source Type: research
