Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health." « Back to Top Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis? https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/ Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't ...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Removal of the Thymus Illustrates the Importance of Thymic Atrophy in Aging
This study demonstrates just how vital the thymus is to maintaining adult health." Link: https://news.harvard.edu/gazette/story/2023/08/turns-out-lowly-thymus-may-be-saving-your-life/ (Source: Fight Aging!)
Source: Fight Aging! - August 10, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

PicnicHealth Raises a $60m Series C to Expand Patient-centered Real-world Data
PicnicHealth, a patient-centered health technology company, today announced the closing of a $60 million Series C financing led by new investor B Capital Group. Existing investors Felicis Ventures and Amplify Partners also joined the round, bringing the total PicnicHealth has raised to more than $100 million. The company also announced plans to build 30 new patient-centered real-world data cohorts, and the addition of Adam Seabrook, Partner at B Capital Group, to the PicnicHealth board of directors. PicnicHealth takes a patient-centered approach to building deep real-world datasets for life sciences researchers. This compl...
Source: EMR and HIPAA - July 1, 2022 Category: Information Technology Authors: Healthcare IT News Tags: Analytics/Big Data Health IT Company Healthcare IT Adam Seabrook Amplify Partner B Capital Group Felicis Ventures Health IT Funding Health IT Fundings Health IT Investment Noga Leviner PicnicHealth Real-World Data Robert Mittendo Source Type: blogs

How is treatment for myasthenia gravis evolving?
Myasthenia gravis (MG) — a medical term that translates as “serious muscle weakness” — is a rare neuromuscular disease. An estimated 30,000 to 60,000 people in the United States have this disorder, which affects people of all ages, sexes, and ethnicities. Recently updated consensus guidelines have added to our knowledge of different forms of myasthenia gravis and improved approaches to treatment. What are the symptoms of myasthenia gravis? Myasthenia gravis impairs the transmission of signals from nerves to muscles at a site called the neuromuscular junction (NMJ), where nerves make contact with muscle. This causes...
Source: Harvard Health Blog - April 12, 2021 Category: Consumer Health News Authors: Pushpa Narayanaswami, MD, FAAN Tags: Autoimmune diseases Neurological conditions Source Type: blogs

E-luminations: Racing Cars Helps Me Live With Degenerative Swallowing Disorder
It’s not often that a person growing up among the cotton fields of southwest Oklahoma goes on to become a successful manager of global technology companies, but Leland White is not your average person. During his career, he built and managed semiconductor manufacturing plants around the world and provided management consulting services to large corporations and federal agencies. After a successful business career, he retired in Colorado to pursue two passions: downhill skiing and high-performance driving. Referred to by family and friends as “Lee,” he turned 78 last spring. I talked to Lee about the challenges he...
Source: American Speech-Language-Hearing Association (ASHA) Press Releases - March 11, 2020 Category: Speech-Language Pathology Authors: Sharon Baker Tags: Health Care Slider Speech-Language Pathology Dysphagia Swallowing Disorders Source Type: blogs

Merry Funtabulously Frivolous Friday Five 264
It's Friday. Boggle your brain with FFFF challenge and some old fashioned trivia. Funtabulously Frivolous Friday Five 264 - Christmas Edition The post Merry Funtabulously Frivolous Friday Five 264 appeared first on Life in the Fast Lane. (Source: Life in the Fast Lane)
Source: Life in the Fast Lane - December 21, 2018 Category: Emergency Medicine Authors: Dr Neil Long Tags: FFFF Awakening Baron Constantin von Economo Christmas BMJ Edrophonium Elf Elfin facies Encephalitis Lethargica Golf Ice test Man flu Myasthenia Gravis Williams syndrome Source Type: blogs

Teleneurology works. Here ’s why.
Teleneurology is the new and vastly expanding practice of neurology involving the use of technology and/or video chat to improve access to services. With an ever-increasing aging population there is and will continue to be a shortage of neurologists in the United States. Teleneurology has increased patient access to neurologists especially in rural areas but also in urban and suburban areas. Practicing as a teleneurologist for the last two years I can log on to secure video chats compliant with the Health Insurance Portability and Accountability Act of 1996 (HIPAA). I see patients in Florida, New Hampshire, North Carolina,...
Source: Kevin, M.D. - Medical Weblog - October 21, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/puja-aggarwal" rel="tag" > Puja Aggarwal, MD < /a > Tags: Conditions Mobile health Neurology Source Type: blogs

A medical intern ’s 3 greatest fears
A 76-year-old gentleman with a history of kidney failure, myasthenia gravis and recently diagnosed with esophageal cancer presented for evaluation of melena and hypotension. The patient was my first admission to the medicine team as an intern, and he was as near to an ICU admission without actually being admitted to the ICU as one could come. After examining the patient, I briefly staffed with the busy attending physician, placed the orders, and wrote the H&P. When I got home later that evening, I logged in remotely, re-checked the orders and re-read my note. At 2:00 a.m., I woke up in a panic — convinced I had accid...
Source: Kevin, M.D. - Medical Weblog - April 19, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/kirk-sidey" rel="tag" > Kirk Sidey, MD < /a > Tags: Education Hospital-Based Medicine Residency Source Type: blogs

Tropical Travel Trouble 007 Mega Malaria Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 007 When you think tropical medicine, malaria has to be near the top. It can be fairly complex and fortunately treatment has become a lot simpler. This post is designed to walk you through the basic principals with links to more in depth teaching if your niche is travel medicine, laboratory diagnostics or management of severe or cerebral malaria. If you stubbled on this post while drinking a cup of tea or sitting on the throne and want a few basi...
Source: Life in the Fast Lane - April 5, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine malaria Plasmodium plasmodium falciparum plasmodium knowles plasmodium malariae plasmodium ovale plasmodium vivax Source Type: blogs

LITFL Review 314
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Welcome to the 314th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM. The Most Fair Dinkum Ripper Beauts of the Week The Bottom Line has a comprehensive review on the role of steroids in sepsis – where w...
Source: Life in the Fast Lane - January 7, 2018 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs

Funtabulously Frivolous Friday Five 199
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 199. Question 1 What does this pastry have in common with cardiology? http://www.waitrose.com + Reveal the Funtabulous Answer expand(document.getElementById('ddet1872942130'));expand(document.getElementById('ddetlink1872942130')) The french call it a “Chocola...
Source: Life in the Fast Lane - July 28, 2017 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five Bazett's formula chocolate torsade gentamicin myasthenia gravis pimped renal colic rollercoaster torsades de pointes william harvey Source Type: blogs

How Do We Understand Common Cognitive Errors Radiologists Make?
Making a diagnostic error is something that many radiologists will grapple with in their careers. According to a study from Johns Hopkins University School Medicine, nearly 75 percent of all medical malpractice suits against radiologists are pursued on the basis of diagnostic errors.    The study ’s researchers attribute overwhelming work responsibilities, increased expectations, bureaucratic protocol, and cognitive biases to diagnostic errors in the field. Cognitive errors are comprised of “faulty perception, failed heuristics, and biases.” They’re essentially shortcuts radiologists utilize in order to make tim...
Source: radRounds - March 19, 2017 Category: Radiology Authors: Julie Morse Source Type: blogs

How we do Understand Common Cognitive Errors Radiologists Make?
Making a diagnostic error is something that many radiologists will grapple with in their careers. According to a study from Johns Hopkins University School Medicine, nearly 75 percent of all medical malpractice suits against radiologists are pursued on the basis of diagnostic errors.    The study ’s researchers attribute overwhelming work responsibilities, increased expectations, bureaucratic protocol, and cognitive biases to diagnostic errors in the field. Cognitive errors are comprised of “faulty perception, failed heuristics, and biases.” They’re essentially shortcuts radiologists utilize in order to make tim...
Source: radRounds - March 1, 2017 Category: Radiology Authors: Julie Morse Source Type: blogs

Notes to myself – 2
Pentobarb coma – BIS should be 10-20 and SR (suppression ratio) should be 70-80 Consider lev albuterol Should give vaccines after coiling of spleen or before if possible No calcium channel blockers post MI definitely and post op in general Toradol inhibits spine healing Don’t do endoscopes with patients in supine position don’t ambulate patients with known dvt’s. wait 2-3 days until clots get stuck. dvt’s even with filter get heparin as much as possible for post phlebitic syndrome and to retard new clot formation diffuse alveolar hemorrhage – secondary to chemo, goodpasture’s, wege...
Source: Inside Surgery - December 31, 2016 Category: Surgery Authors: Editor Tags: General Source Type: blogs