Steroid-Eluting Implants: An Adjunctive Therapy After Double-Stage Laryngotracheal Reconstruction
CONCLUSIONS: Steroid-eluting implants appear to be a safe and effective adjunctive therapy in the routine surveillance of pediatric patients with a tracheostomy who have undergone dsLTR. They may help combat granulation formation and restenosis seen in some dsLTR patients.PMID:37776286 | DOI:10.1177/00034894231202067 (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - September 30, 2023 Category: ENT & OMF Authors: Emily Drury Brian Anderson Michael Haupert Prasad John Thottam Source Type: research

Steroid-Eluting Implants: An Adjunctive Therapy After Double-Stage Laryngotracheal Reconstruction
CONCLUSIONS: Steroid-eluting implants appear to be a safe and effective adjunctive therapy in the routine surveillance of pediatric patients with a tracheostomy who have undergone dsLTR. They may help combat granulation formation and restenosis seen in some dsLTR patients.PMID:37776286 | DOI:10.1177/00034894231202067 (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - September 30, 2023 Category: ENT & OMF Authors: Emily Drury Brian Anderson Michael Haupert Prasad John Thottam Source Type: research

Steroid-Eluting Implants: An Adjunctive Therapy After Double-Stage Laryngotracheal Reconstruction
CONCLUSIONS: Steroid-eluting implants appear to be a safe and effective adjunctive therapy in the routine surveillance of pediatric patients with a tracheostomy who have undergone dsLTR. They may help combat granulation formation and restenosis seen in some dsLTR patients.PMID:37776286 | DOI:10.1177/00034894231202067 (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - September 30, 2023 Category: ENT & OMF Authors: Emily Drury Brian Anderson Michael Haupert Prasad John Thottam Source Type: research

Vitamin D supplementation improves the therapeutic effect of mometasone on allergic rhinitis
This study aimed to investigate the efficacy and safety of vitamin D supplementation in the treatment of allergic rhinitis (AR) using mometasone. A total of 140 patients with moderate and severe AR treated at our hospital between January 2017 and August 2020 were recruited as subjects for this study. The patients were randomly divided into control and experimental groups, with 70 patients in each group. Mometasone nasal spray was used in both groups, and vitamin D was administered to the experimental group for four weeks. The total nasal symptom scores (TNSS) and rhinoconjunctivitis quality of life questionnaire (RQLQ) wer...
Source: Acta Biochim Pol - September 16, 2023 Category: Biochemistry Authors: Minfei Guo Source Type: research

Efficacy, Safety, and Systemic Exposure of Once-Daily Indacaterol Acetate in Pediatric Asthma: A Randomized, Double-Blind, Controlled Dose-Finding Study
ConclusionsOnce-daily IND 75 μg and IND 150 μg via Breezhaler® in combination with background ICS therapy provided substantial bronchodilation in children with asthma and were well tolerated. Taken together, these clinical and systemic exposure findings support IND 75 μg as the most appropriate dose for evaluation in Phase III trials in combination with MF in pediatric asthma.Trial RegistrationClinicalTrials.gov (NCT02892019; 08-Sep-2016). (Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - September 8, 2023 Category: Drugs & Pharmacology Source Type: research

Mepitel Film for the prevention of acute radiation dermatitis in head and neck cancer: a systematic review and meta-analysis of randomized controlled trials
CONCLUSION: While there were discrepancies across studies, Mepitel Film demonstrated a decrease in the incidence of grade 2-3 RD and moist desquamation. These findings emphasize the need for further examining Mepitel Film's efficacy across diverse patient groups and the importance of standardizing RD severity assessment methodologies and control arms.PMID:37594538 | DOI:10.1007/s00520-023-07988-w (Source: Cancer Control)
Source: Cancer Control - August 18, 2023 Category: Cancer & Oncology Authors: Shing Fung Lee Henry C Y Wong Adrian Wai Chan Saverio Caini Saba Shariati Dirk Rades Raymond J Chan Samantha K F Kennedy Julie Ryan Wolf Corina van den Hurk Tara Behroozian Pierluigi Bonomo Francis C H Ho Edward Chow Patries Herst Source Type: research

Mepitel Film for the prevention of acute radiation dermatitis in head and neck cancer: a systematic review and meta-analysis of randomized controlled trials
ConclusionWhile there were discrepancies across studies, Mepitel Film demonstrated a decrease in the incidence of grade 2 –3 RD and moist desquamation. These findings emphasize the need for further examining Mepitel Film’s efficacy across diverse patient groups and the importance of standardizing RD severity assessment methodologies and control arms. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - August 18, 2023 Category: Cancer & Oncology Source Type: research

Outcomes of Frontal Sinus Stenting With Steroid Impregnated Microsponge Versus Steroid-Eluting Implant
CONCLUSION: FSO patency for both stents was similar, although TICP had significantly lower costs per unit. Additional comparative trials may be helpful for guiding clinicians on the appropriate clinical situations for the use of these devices.PMID:37408359 | DOI:10.1177/19458924231186901 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - July 6, 2023 Category: ENT & OMF Authors: Tripti Brar Adam Brown Amar Miglani Devyani Lal Michael J Marino Source Type: research

Outcomes of Frontal Sinus Stenting With Steroid Impregnated Microsponge Versus Steroid-Eluting Implant
CONCLUSION: FSO patency for both stents was similar, although TICP had significantly lower costs per unit. Additional comparative trials may be helpful for guiding clinicians on the appropriate clinical situations for the use of these devices.PMID:37408359 | DOI:10.1177/19458924231186901 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - July 6, 2023 Category: ENT & OMF Authors: Tripti Brar Adam Brown Amar Miglani Devyani Lal Michael J Marino Source Type: research