Off-Label Use of Ciprofloxacin/Dexamethasone Drops in the Pediatric Upper Airway: Case Presentation and Review of Adverse Effects
CONCLUSION: This is the first reported pediatric case of increased blood glucose levels associated with intranasal steroid suspensions, to the best of our knowledge. Counseling families on precise dose administration and potential endocrine disturbances is critical when prescribing these medications for off-label use in infants and small children, particularly among patients with underlying endocrine disorders such as diabetes.PMID:35703381 | DOI:10.1177/00034894221104461 (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 15, 2022 Category: ENT & OMF Authors: Tom Ben-Dov Jackie Yang Max M April Source Type: research

Off-Label Use of Ciprofloxacin/Dexamethasone Drops in the Pediatric Upper Airway: Case Presentation and Review of Adverse Effects
CONCLUSION: This is the first reported pediatric case of increased blood glucose levels associated with intranasal steroid suspensions, to the best of our knowledge. Counseling families on precise dose administration and potential endocrine disturbances is critical when prescribing these medications for off-label use in infants and small children, particularly among patients with underlying endocrine disorders such as diabetes.PMID:35703381 | DOI:10.1177/00034894221104461 (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 15, 2022 Category: ENT & OMF Authors: Tom Ben-Dov Jackie Yang Max M April Source Type: research

Off-Label Use of Ciprofloxacin/Dexamethasone Drops in the Pediatric Upper Airway: Case Presentation and Review of Adverse Effects
CONCLUSION: This is the first reported pediatric case of increased blood glucose levels associated with intranasal steroid suspensions, to the best of our knowledge. Counseling families on precise dose administration and potential endocrine disturbances is critical when prescribing these medications for off-label use in infants and small children, particularly among patients with underlying endocrine disorders such as diabetes.PMID:35703381 | DOI:10.1177/00034894221104461 (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 15, 2022 Category: ENT & OMF Authors: Tom Ben-Dov Jackie Yang Max M April Source Type: research

Off-Label Use of Ciprofloxacin/Dexamethasone Drops in the Pediatric Upper Airway: Case Presentation and Review of Adverse Effects
CONCLUSION: This is the first reported pediatric case of increased blood glucose levels associated with intranasal steroid suspensions, to the best of our knowledge. Counseling families on precise dose administration and potential endocrine disturbances is critical when prescribing these medications for off-label use in infants and small children, particularly among patients with underlying endocrine disorders such as diabetes.PMID:35703381 | DOI:10.1177/00034894221104461 (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 15, 2022 Category: ENT & OMF Authors: Tom Ben-Dov Jackie Yang Max M April Source Type: research

Clinical observation on moxibustion at Baihui (GV20) plus Tuina for children with postnasal drip syndrome
ConclusionThe clinical efficacy of moxibustion at Baihui (GV20) plus Tuina at the head and face on the basis of nasal spray with Western medicine is more significant than that of Western medicine alone for PNDS in children. (Source: Journal of Acupuncture and Tuina Science)
Source: Journal of Acupuncture and Tuina Science - June 1, 2022 Category: Complementary Medicine Source Type: research

Use of intraoperative frontal sinus mometasone ‐eluting stents decreased interleukin 5 and interleukin 13 in patients with chronic rhinosinusitis with nasal polyps
ConclusionAlthough patients who received intraoperative frontal MES had significantly higher pre-ESS MM IL-13 and ECP, patients who received frontal MES had lower concentrations of IL-4 and IL-13 than those who did not at a median of 8 months post-ESS. However, these changes did not correspond to significantly different measures of symptomatic or radiographic disease severity. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 20, 2022 Category: Allergy & Immunology Authors: Alexander L. Schneider, Samuel D. Racette, Anthony K. Kang, Abhita T. Reddy, Julia H. Huang, David S. Lehmann, Caroline P.E. Price, Jacob G. Eide, Samuel R. Rodeghiero, David B. Conley, Kevin C. Welch, Robert C. Kern, Stephanie Shintani ‐Smi Tags: ORIGINAL ARTICLE Source Type: research

Particulate Matter Exposure and the Changes in Immune Biomarkers: Effects of Biyeom-Go on the Nasal Mucosa of Patients with Allergic Rhinitis and a Particulate Matter-Treated Mouse Model
This study was to investigate the effects of Biyeom-go (BYG, an herbal formula) on immune biomarkers present in the nasal mucosa of patients with allergic rhinitis under exposure to particulate matter 2.5 (PM2.5), and on changes in goblet cells and immune biomarkers in mice under exposure to Korea diesel particulate matter (KDP20). Thirty patients showing characteristic allergic rhinitis symptoms were enrolled in Jeonju-si, Korea, and treated with BYG thrice a day for four weeks. Changes in the expression of immune biomarkers (interleukin 4 (IL-4), IL-5, IL-8, IL-13, IL-33, and thymic stromal lymphopoietin (TSLP) mRNA), to...
Source: Evidence-based Complementary and Alternative Medicine - April 5, 2022 Category: Complementary Medicine Authors: Bongkyun Park Byoung-Kab Kang Ae-Ran Kim Jung In Kang Dong-Hyo Lee Chang Sop Yang Young Sook Kim Chan-Sik Kim Source Type: research

Use of intra ‐operative frontal sinus mometasone‐eluting stents decreased IL‐5 and IL‐13 in patients with chronic rhinosinusitis with nasal polyps
Conclusion: Although patients who received intra-operative frontal MES had significantly higher pre-ESS MM IL-13 and ECP, patients who received frontal MES had lower concentrations of IL-4 and IL-13 than those who did not at a median 8 months post-ESS. However, these changes did not correspond to significantly different measures of symptomatic or radiographic disease severity.This article is protected by copyright. All rights reserved (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - April 1, 2022 Category: Allergy & Immunology Authors: Alexander L. Schneider, Samuel D. Racette, Anthony K. Kang, Abhita T. Reddy, Julia H. Huang, David S. Lehmann, Caroline P.E. Price, Jacob G. Eide, Samuel R. Rodeghiero, David B. Conley, Kevin C. Welch, Robert C. Kern, Stephanie Shintani ‐Smi Tags: ORIGINAL ARTICLE Source Type: research

Long-term safety of once-daily indacaterol acetate/glycopyrronium bromide/mometasone furoate high-dose, and indacaterol acetate/mometasone furoate high-dose, in Japanese patients with inadequately controlled asthma: Results from two open-label, 52-week studies
Conclusions: Once-daily IND/GLY/MF and IND/MF high-dose were well-tolerated in Japanese patients with inadequately controlled asthma. No unexpected safety findings were observed.PMID:35348408 | DOI:10.1080/02770903.2022.2056048 (Source: Journal of Asthma)
Source: Journal of Asthma - March 29, 2022 Category: Respiratory Medicine Authors: Hironori Sagara Peter D'Andrea Ana-Maria Tanase Abhijit Pethe Yukina Tanaka Kazutaka Matsuo Motoi Hosoe Yoichi Nakamura Source Type: research