Efficacy and safety of GSP301 nasal spray in children aged 6-11 with seasonal allergic rhinitis
CONCLUSION: GSP301 was well tolerated and efficacious for treating SAR symptoms in pediatric subjects and demonstrated a favorable safety profile.CLINICAL TRIAL REGISTRATION: NCT03463031.PMID:35926824 | DOI:10.1016/j.anai.2022.07.029 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - August 4, 2022 Category: Allergy & Immunology Authors: Bruce M Prenner Niran J Amar Frank C Hampel Cynthia F Caracta Wen Wu Source Type: research
Efficacy and safety of GSP301 nasal spray in children aged 6-11 with seasonal allergic rhinitis
GSP301 nasal spray is a fixed-dose combination of the antihistamine olopatadine hydrochloride and the corticosteroid mometasone furoate. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - August 1, 2022 Category: Allergy & Immunology Authors: Bruce M. Prenner, Niran J. Amar, Frank C. Hampel, Cynthia F. Caracta, Wen Wu Tags: Original Article Source Type: research
Efficacy and safety of GSP301 nasal spray in children aged 6 to 11 years with seasonal allergic rhinitis
GSP301 nasal spray is a fixed-dose combination of the antihistamine olopatadine hydrochloride and the corticosteroid mometasone furoate. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - August 1, 2022 Category: Allergy & Immunology Authors: Bruce M. Prenner, Niran J. Amar, Frank C. Hampel, Cynthia F. Caracta, Wen Wu Tags: Original Article Source Type: research
The short-term effects of intranasal steroids on intraocular pressure in pediatric population
ConclusionSince children have greater risk for steroid-induced ocular hypertensive response than adults, ophthalmologic evaluation must be recommended in children receiving intranasal steroids. (Source: International Ophthalmology)
Source: International Ophthalmology - July 12, 2022 Category: Opthalmology Source Type: research
Clinical Efficacy of Tuomin Zhiti Decoction in Allergic Rhinitis
This study aimed to assess the efficacy of the Tuomin Zhiti decoction in allergic rhinitis and to provide a reference for clinical treatment. One hundred patients with AR treated in the Department of Otolaryngology of our hospital from January 2019 to December 2020 were recruited and assigned via a random number table method (1 : 1) to receive either oral loratadine and mometasone nasal spray (control group) or the Tuomin Zhiti decoction plus oral loratadine and mometasone nasal spray (study group). The total clinical efficacy was 86% (43/50) in the study group, which was significantly higher than that of 64% (32/50) in th...
Source: Evidence-based Complementary and Alternative Medicine - July 1, 2022 Category: Complementary Medicine Authors: Jian-Xin Zhang Wen-Yan Wang Source Type: research
Pharmacokinetic Evidence of Steady and Sustained Drug Release from Long-Acting Implantable Corticosteroid Matrices for Chronic Rhinosinusitis
CONCLUSION: LYR-210 achieved dose-dependent, continuous local MF delivery at a steady rate with low systemic exposure for months.PMID:35708181 | DOI:10.1177/19458924221107200 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - June 16, 2022 Category: ENT & OMF Authors: Randall A Ow Steven Shotts Venkata Kakarlapudi John McIntyre Robert M Naclerio Changcheng You Alexander Pappas Lindsay Brayton Yina Kuang James Shao Source Type: research
Pharmacokinetic Evidence of Steady and Sustained Drug Release from Long-Acting Implantable Corticosteroid Matrices for Chronic Rhinosinusitis
CONCLUSION: LYR-210 achieved dose-dependent, continuous local MF delivery at a steady rate with low systemic exposure for months.PMID:35708181 | DOI:10.1177/19458924221107200 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - June 16, 2022 Category: ENT & OMF Authors: Randall A Ow Steven Shotts Venkata Kakarlapudi John McIntyre Robert M Naclerio Changcheng You Alexander Pappas Lindsay Brayton Yina Kuang James Shao Source Type: research
Pharmacokinetic Evidence of Steady and Sustained Drug Release from Long-Acting Implantable Corticosteroid Matrices for Chronic Rhinosinusitis
CONCLUSION: LYR-210 achieved dose-dependent, continuous local MF delivery at a steady rate with low systemic exposure for months.PMID:35708181 | DOI:10.1177/19458924221107200 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - June 16, 2022 Category: ENT & OMF Authors: Randall A Ow Steven Shotts Venkata Kakarlapudi John McIntyre Robert M Naclerio Changcheng You Alexander Pappas Lindsay Brayton Yina Kuang James Shao Source Type: research
Pharmacokinetic Evidence of Steady and Sustained Drug Release from Long-Acting Implantable Corticosteroid Matrices for Chronic Rhinosinusitis
CONCLUSION: LYR-210 achieved dose-dependent, continuous local MF delivery at a steady rate with low systemic exposure for months.PMID:35708181 | DOI:10.1177/19458924221107200 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - June 16, 2022 Category: ENT & OMF Authors: Randall A Ow Steven Shotts Venkata Kakarlapudi John McIntyre Robert M Naclerio Changcheng You Alexander Pappas Lindsay Brayton Yina Kuang James Shao Source Type: research
Pharmacokinetic Evidence of Steady and Sustained Drug Release from Long-Acting Implantable Corticosteroid Matrices for Chronic Rhinosinusitis
CONCLUSION: LYR-210 achieved dose-dependent, continuous local MF delivery at a steady rate with low systemic exposure for months.PMID:35708181 | DOI:10.1177/19458924221107200 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - June 16, 2022 Category: ENT & OMF Authors: Randall A Ow Steven Shotts Venkata Kakarlapudi John McIntyre Robert M Naclerio Changcheng You Alexander Pappas Lindsay Brayton Yina Kuang James Shao Source Type: research
Pharmacokinetic Evidence of Steady and Sustained Drug Release from Long-Acting Implantable Corticosteroid Matrices for Chronic Rhinosinusitis
CONCLUSION: LYR-210 achieved dose-dependent, continuous local MF delivery at a steady rate with low systemic exposure for months.PMID:35708181 | DOI:10.1177/19458924221107200 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - June 16, 2022 Category: ENT & OMF Authors: Randall A Ow Steven Shotts Venkata Kakarlapudi John McIntyre Robert M Naclerio Changcheng You Alexander Pappas Lindsay Brayton Yina Kuang James Shao Source Type: research
Pharmacokinetic Evidence of Steady and Sustained Drug Release from Long-Acting Implantable Corticosteroid Matrices for Chronic Rhinosinusitis
CONCLUSION: LYR-210 achieved dose-dependent, continuous local MF delivery at a steady rate with low systemic exposure for months.PMID:35708181 | DOI:10.1177/19458924221107200 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - June 16, 2022 Category: ENT & OMF Authors: Randall A Ow Steven Shotts Venkata Kakarlapudi John McIntyre Robert M Naclerio Changcheng You Alexander Pappas Lindsay Brayton Yina Kuang James Shao Source Type: research
Off-Label Use of Ciprofloxacin/Dexamethasone Drops in the Pediatric Upper Airway: Case Presentation and Review of Adverse Effects
CONCLUSION: This is the first reported pediatric case of increased blood glucose levels associated with intranasal steroid suspensions, to the best of our knowledge. Counseling families on precise dose administration and potential endocrine disturbances is critical when prescribing these medications for off-label use in infants and small children, particularly among patients with underlying endocrine disorders such as diabetes.PMID:35703381 | DOI:10.1177/00034894221104461 (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 15, 2022 Category: ENT & OMF Authors: Tom Ben-Dov Jackie Yang Max M April Source Type: research
