What Do I Do When My Antidepressant Stops Working?
This study examined 103 patients with bipolar 1 disorder who, despite taking a mood stabilizer, experienced frequent relapses. During a 12-month period, the group receiving cognitive therapy had significantly fewer bipolar episodes and reported less mood symptoms on the monthly mood questionnaires. They also had less fluctuation in manic symptoms. It’s normal to panic in the days and weeks your symptoms return; however, as you can see, there are many options to pursue. If the first approach doesn’t work, try another. Persevere until you achieve full remission and feel like yourself again. It will happen. Trust me on th...
Source: World of Psychology - March 1, 2019 Category: Psychiatry & Psychology Authors: Therese J. Borchard Tags: Antidepressant Bipolar Depression General Medications Manic Episode Mood Disorder Mood Stabilizer Relapse Source Type: blogs

Does Digital Health Technology Know Women?
The majority of period tracker apps fail women, fitness trackers, and wearables fail pregnant women terribly. They were most probably designed and developed by men, and most likely not consulted by future users. We looked around at the women’s health and “femtech” market and found that digital health technology has yet to live up to female expectations. So far, the area is under-researched, underfunded and not understood. Technology – Still a man’s world In spite of the slogan of diversity pinned on the flag of many tech companies, the field is highly dominated by men. It is easy to imagine Silicon Val...
Source: The Medical Futurist - February 21, 2019 Category: Information Technology Authors: nora Tags: Business Future of Medicine Medical Professionals Patients digital digital health technology diversity female femtech gender gender disparity Innovation social issues society woman women women's health Source Type: blogs

Which hormone injection works best in IVF ?
There's still a lot of confusion as to whether we should use urinary gonadotropins or recombinant gonadotropins in IVF for superovulation ( = helping patients grow lots of follicles).Historically, we used urinary gonadotropins for many years. These are biological products , extracted from the urine of menopausal women , and they still work very well.The problem is that there is a lot of batch to batch variation , because the quality of the extracted hormones is not always consistent, and this can create a lot of problems, because patients don't respond well to the superovulation. This is why it's so important for doctors t...
Source: Dr.Malpani's Blog - February 21, 2019 Category: Reproduction Medicine Source Type: blogs

Preserving fertility during cancer treatments
Cancer treatment — and cancer itself — can threaten fertility. This is a tremendously important survivorship issue for many people. As an oncologist, I’m often asked questions about preserving fertility during cancer treatment. If this issue affects you, here is an overview of key options. When should you talk to your cancer team about fertility? Future children may not be foremost on your mind when you are diagnosed with cancer. Soon afterward, though, it’s worth talking to your doctor about fertility issues, if this is important to you now or might one day become important. Your doctor can explain: the risk that...
Source: Harvard Health Blog - February 4, 2019 Category: Consumer Health News Authors: Ann Partridge, MD, MPH Tags: Cancer Fertility Infertility Source Type: blogs

Fight Aging! Newsletter, February 4th 2019
In this study, we examined the benefits of early-onset, lifelong AET on predictors of health, inflammation, and cancer incidence in a naturally aging mouse model. Lifelong, voluntary wheel-running (O-AET; 26-month-old) prevented age-related declines in aerobic fitness and motor coordination vs. age-matched, sedentary controls (O-SED). AET also provided partial protection against sarcopenia, dynapenia, testicular atrophy, and overall organ pathology, hence augmenting the 'physiologic reserve' of lifelong runners. Systemic inflammation, as evidenced by a chronic elevation in 17 of 18 pro- and anti-inflammatory cytokin...
Source: Fight Aging! - February 3, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

GrimAge is the Latest Evolution of the Epigenetic Clock
The original epigenetic clock is a measure of age, a weighted algorithmic combination of specific DNA methylation sites on the genome. Numerous variations on this theme are being produced, and here I'll point out news on the latest, a metric called GrimAge. DNA methylation is an epigenetic mechanism that steers protein production and thus cell behavior. Epigenetic clocks correlate well with chronological age, and it has been shown that populations of older individuals with pronounced age-related disease or otherwise exhibiting higher mortality rates tend to have higher epigenetic ages. There are some problematic exc...
Source: Fight Aging! - January 30, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Aging: Some points to ponder
What to call this period? Today I am 72. I am not middle aged. I am not old old either. Yet I am different from when I was in my 50s or 60s. I have this keen sense about the onrushing end, that I have perhaps 15 years or so, and not likely more, of active life ahead. That changes things. I see myself well  within the last quarter of my life. But who knows? That is one of the issues of this stage.Some factors I reflect on --* Men continue to be able to sire children into old age; for women, menopause marks the end of reproduction -- how does this affect the last quarter?  *There are so few places to see bodies showing age...
Source: Jung At Heart - January 27, 2019 Category: Psychiatry & Psychology Source Type: blogs

Bleeding after menopause: Get it checked out
Bleeding after menopause can be disconcerting, but the good news is, more than 90% of the time it’s not caused by a serious condition, according to a study in JAMA Internal Medicine. That said, the study also reinforces the idea that postmenopausal bleeding should always be checked out by your doctor to rule out endometrial cancer, a cancer of the uterine lining, says Dr. Ross Berkowitz, William H. Baker Professor of Gynecology at Harvard Medical School. This is because the study also found more than 90% of women who did have endometrial cancer had experienced postmenopausal bleeding. And screening all women who experie...
Source: Harvard Health Blog - January 18, 2019 Category: Consumer Health News Authors: Kelly Bilodeau Tags: Health Source Type: blogs

Heart disease and breast cancer: Can women cut risk for both?
Very often I encounter women who are far more worried about breast cancer than they are about heart disease. But women have a greater risk of dying from heart disease than from all cancers combined. This is true for women of all races and ethnicities. Yet only about 50% of women realize that they are at greater risk from heart disease than from anything else. Currently in the US, three million women are living with breast cancer, which causes one in 31 deaths. Almost 50 million women have cardiovascular disease, which encompasses heart disease and strokes and causes one in three deaths. Here’s what’s really interestin...
Source: Harvard Health Blog - January 8, 2019 Category: Consumer Health News Authors: Monique Tello, MD, MPH Tags: Breast Cancer Exercise and Fitness Health Healthy Eating Heart Health Women's Health Source Type: blogs

The Estrogen Dilemma and Alzheimer's Disease
This article cuts across a broad spectrum of diseases, but is focused on hormones, estrogen and something called the timing hypothesis.This proposition, that estrogen ’s effects on our minds and our bodies may depend heavily upon when we first start taking it, is a controversial and very big idea. It has a working nickname: “the timing hypothesis.”There are some very interesting hypotheses about the health of the brain and Alzheimer's in the article.If the timing hypothesis proves right and estrogen really does protect brains and hearts as long as we start it "at the right time", the calculation only grows that much ...
Source: Alzheimer's Reading Room, The - December 11, 2018 Category: Neurology Tags: Alzheimer's disease estrogen facts about estrogen health life news women Source Type: blogs

Fight Aging! Newsletter, December 3rd 2018
This article, however, is more of a commentary on high level strategy and the effects of regulation, coupled with a desire to forge ahead rather than hold back in the matter of treating aging, thus I concur with much more of what is said than is usually the case. For decades, one of the most debated questions in gerontology was whether aging is a disease or the norm. At present, excellent reasoning suggests aging should be defined as a disease - indeed, aging has been referred to as "normal disease." Aging is the sum of all age-related diseases and this sum is the best biomarker of aging. Aging and its diseases ar...
Source: Fight Aging! - December 2, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Why do Women Experience Worse Health than Men in Late Life?
It is well known that females of many species live longer than males. Some fundamental aspects of gender roles in mating and reproduction tend to lead to this outcome. It isn't peculiar to our species, so it can't have anything to do with technology or the sociology that comes with intelligence. Thus the dominant arguments really have to be evolutionary in nature. It is less well known that, in our species at least, women have worse health than men in later life, despite a greater life expectancy. This also probably arises at root from fundamental aspects of gender roles, but there is a great deal of room to argue for any ...
Source: Fight Aging! - November 30, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

The new cholesterol guidelines: What you need to know
The new cholesterol guidelines from the American College of Cardiology and American Heart Association are out! These guidelines — last updated in 2013 — have been highly anticipated by the cardiology and broader medical community. They have been approved by a variety of additional professional societies, including the American Diabetes Association. Thus, the majority of physicians are very likely to follow them. So, what exactly is new and what do you need to know? It starts with a healthy lifestyle, with statins for those who need them A healthy diet and regular physical activity are recommended for all age groups as ...
Source: Harvard Health Blog - November 26, 2018 Category: Consumer Health News Authors: Deepak Bhatt, MD, MPH Tags: Health Heart Health Source Type: blogs

Don't Wait for Aging to be Classified as a Disease
This article, however, is more of a commentary on high level strategy and the effects of regulation, coupled with a desire to forge ahead rather than hold back in the matter of treating aging, thus I concur with much more of what is said than is usually the case. For decades, one of the most debated questions in gerontology was whether aging is a disease or the norm. At present, excellent reasoning suggests aging should be defined as a disease - indeed, aging has been referred to as "normal disease." Aging is the sum of all age-related diseases and this sum is the best biomarker of aging. Aging and its diseases ar...
Source: Fight Aging! - November 26, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Hormone therapy for depression: Are the risks worth the benefits?
When you think of menopause, you might think of hot flashes and night sweats. But many women also experience symptoms of depression. The risk of depression doubles or even quadruples during the menopausal transition, which has researchers looking for ways to address — or even prevent — the problem. One study published in JAMA Psychiatry found that hormone therapy may help ward off symptoms of peri- and postmenopausal depression in some women. Researchers found that perimenopausal and early postmenopausal women who were treated with hormones were less likely to experience symptoms of depression than women in the study w...
Source: Harvard Health Blog - November 16, 2018 Category: Consumer Health News Authors: Kelly Bilodeau Tags: Anxiety and Depression Health Menopause Source Type: blogs