T Lymphocyte Interferon-gamma Response to Anaplasmataceae-related Major Surface Proteins and Ankyrin A in Fibromyalgia
CONCLUSION: Anaplasmataceae may play an aetiological role in fibromyalgia.PMID:38375844 | DOI:10.2174/0118715273274091231207101522 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - February 20, 2024 Category: Drugs & Pharmacology Authors: Basant K Puri Rosemarie Preyer Gary S Lee Armin Schwarzbach Source Type: research

T Lymphocyte Interferon-gamma Response to Anaplasmataceae-related Major Surface Proteins and Ankyrin A in Fibromyalgia
CONCLUSION: Anaplasmataceae may play an aetiological role in fibromyalgia.PMID:38375844 | DOI:10.2174/0118715273274091231207101522 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - February 20, 2024 Category: Drugs & Pharmacology Authors: Basant K Puri Rosemarie Preyer Gary S Lee Armin Schwarzbach Source Type: research

T Lymphocyte Interferon-gamma Response to Anaplasmataceae-related Major Surface Proteins and Ankyrin A in Fibromyalgia
CONCLUSION: Anaplasmataceae may play an aetiological role in fibromyalgia.PMID:38375844 | DOI:10.2174/0118715273274091231207101522 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - February 20, 2024 Category: Drugs & Pharmacology Authors: Basant K Puri Rosemarie Preyer Gary S Lee Armin Schwarzbach Source Type: research

Surveillance for Lyme Disease After Implementation of a Revised Case Definition - United States, 2022
MMWR Morb Mortal Wkly Rep. 2024 Feb 15;73(6):118-123. doi: 10.15585/mmwr.mm7306a1.ABSTRACTLyme disease, a tickborne zoonosis caused by certain species of Borrelia spirochetes, is the most common vectorborne disease in the United States. Approximately 90% of all cases are reported from 15 high-incidence jurisdictions in the Northeast, mid-Atlantic, and upper-Midwest regions. After the implementation of a revised surveillance case definition in 2022, high-incidence jurisdictions report cases based on laboratory evidence alone, without need for additional clinical information. In 2022, 62,551 Lyme disease cases were reported ...
Source: MMWR Morb Mortal Wkl... - February 15, 2024 Category: Epidemiology Authors: Kiersten J Kugeler Austin Earley Paul S Mead Alison F Hinckley Source Type: research

Surveillance for Lyme Disease After Implementation of a Revised Case Definition - United States, 2022
MMWR Morb Mortal Wkly Rep. 2024 Feb 15;73(6):118-123. doi: 10.15585/mmwr.mm7306a1.ABSTRACTLyme disease, a tickborne zoonosis caused by certain species of Borrelia spirochetes, is the most common vectorborne disease in the United States. Approximately 90% of all cases are reported from 15 high-incidence jurisdictions in the Northeast, mid-Atlantic, and upper-Midwest regions. After the implementation of a revised surveillance case definition in 2022, high-incidence jurisdictions report cases based on laboratory evidence alone, without need for additional clinical information. In 2022, 62,551 Lyme disease cases were reported ...
Source: MMWR Morb Mortal Wkl... - February 15, 2024 Category: Epidemiology Authors: Kiersten J Kugeler Austin Earley Paul S Mead Alison F Hinckley Source Type: research

Surveillance for Lyme Disease After Implementation of a Revised Case Definition - United States, 2022
MMWR Morb Mortal Wkly Rep. 2024 Feb 15;73(6):118-123. doi: 10.15585/mmwr.mm7306a1.ABSTRACTLyme disease, a tickborne zoonosis caused by certain species of Borrelia spirochetes, is the most common vectorborne disease in the United States. Approximately 90% of all cases are reported from 15 high-incidence jurisdictions in the Northeast, mid-Atlantic, and upper-Midwest regions. After the implementation of a revised surveillance case definition in 2022, high-incidence jurisdictions report cases based on laboratory evidence alone, without need for additional clinical information. In 2022, 62,551 Lyme disease cases were reported ...
Source: MMWR Morb Mortal Wkl... - February 15, 2024 Category: Epidemiology Authors: Kiersten J Kugeler Austin Earley Paul S Mead Alison F Hinckley Source Type: research

Surveillance for Lyme Disease After Implementation of a Revised Case Definition - United States, 2022
MMWR Morb Mortal Wkly Rep. 2024 Feb 15;73(6):118-123. doi: 10.15585/mmwr.mm7306a1.ABSTRACTLyme disease, a tickborne zoonosis caused by certain species of Borrelia spirochetes, is the most common vectorborne disease in the United States. Approximately 90% of all cases are reported from 15 high-incidence jurisdictions in the Northeast, mid-Atlantic, and upper-Midwest regions. After the implementation of a revised surveillance case definition in 2022, high-incidence jurisdictions report cases based on laboratory evidence alone, without need for additional clinical information. In 2022, 62,551 Lyme disease cases were reported ...
Source: MMWR Morb Mortal Wkl... - February 15, 2024 Category: Epidemiology Authors: Kiersten J Kugeler Austin Earley Paul S Mead Alison F Hinckley Source Type: research

Surveillance for Lyme Disease After Implementation of a Revised Case Definition - United States, 2022
MMWR Morb Mortal Wkly Rep. 2024 Feb 15;73(6):118-123. doi: 10.15585/mmwr.mm7306a1.ABSTRACTLyme disease, a tickborne zoonosis caused by certain species of Borrelia spirochetes, is the most common vectorborne disease in the United States. Approximately 90% of all cases are reported from 15 high-incidence jurisdictions in the Northeast, mid-Atlantic, and upper-Midwest regions. After the implementation of a revised surveillance case definition in 2022, high-incidence jurisdictions report cases based on laboratory evidence alone, without need for additional clinical information. In 2022, 62,551 Lyme disease cases were reported ...
Source: MMWR Morb Mortal Wkl... - February 15, 2024 Category: Epidemiology Authors: Kiersten J Kugeler Austin Earley Paul S Mead Alison F Hinckley Source Type: research

Surveillance for Lyme Disease After Implementation of a Revised Case Definition - United States, 2022
MMWR Morb Mortal Wkly Rep. 2024 Feb 15;73(6):118-123. doi: 10.15585/mmwr.mm7306a1.ABSTRACTLyme disease, a tickborne zoonosis caused by certain species of Borrelia spirochetes, is the most common vectorborne disease in the United States. Approximately 90% of all cases are reported from 15 high-incidence jurisdictions in the Northeast, mid-Atlantic, and upper-Midwest regions. After the implementation of a revised surveillance case definition in 2022, high-incidence jurisdictions report cases based on laboratory evidence alone, without need for additional clinical information. In 2022, 62,551 Lyme disease cases were reported ...
Source: MMWR Morb Mortal Wkl... - February 15, 2024 Category: Epidemiology Authors: Kiersten J Kugeler Austin Earley Paul S Mead Alison F Hinckley Source Type: research

Delayed Diagnosis of Locally Acquired Lyme Disease, Central North Carolina, USA
R. M. Boyce et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - February 14, 2024 Category: Infectious Diseases Source Type: research

The major epidemiologic, microbiologic, immunologic, and clinical aspects of Lyme disease that form the basis for a newly developed vaccine that may become available soon for human use
Working together, two major pharmaceutical companies have developed a Lyme disease vaccine consisting of recombinant-derived outer surface protein A (OspA) of the etiologic agent Borrelia burgdorferi. Multiple clinical trials have shown the vaccine to have good safety and efficacy results, and it is hoped that it would become available for human use at least by the year 2025 after receiving approval from the U.S. Food and Drug Administration. There are still challenges left to ensure that the vaccine has, at most, minimal side effects. Also, because the previously developed Lyme disease vaccine was discontinued in 2002 aft...
Source: Frontiers in Immunology - February 14, 2024 Category: Allergy & Immunology Source Type: research

High Prevalence of Borrelia burgdorferi Antibodies in Jaworzno, Poland: A Retrospective Study Revealing Endemic Lyme Borreliosis
CONCLUSIONS The ELISA method obtained similar values for positive, negative, and equivocal results in the serological test. This was reflected in the survey conducted on residents who reported a tick bite and later received a positive result in the ELISA test as well as an approximate time between the bite and removal of the tick.PMID:38327041 | PMC:PMC10863337 | DOI:10.12659/MSM.943203 (Source: Medical Science Monitor)
Source: Medical Science Monitor - February 8, 2024 Category: Research Authors: Barbara Kole żyńska Krzysztof Solarz Weronika Wieczorek Dorota Sagan Dariusz Boro ń Rafa ł Staszkiewicz Dawid Soba ński Tomasz Sirek Anna Janik Piotr Łojko Beniamin Oskar Grabarek Source Type: research

Dysautonomia following Lyme disease: a key component of post-treatment Lyme disease syndrome?
Dysautonomia, or dysfunction of the autonomic nervous system (ANS), may occur following an infectious insult and can result in a variety of debilitating, widespread, and often poorly recognized symptoms. Dysautonomia is now widely accepted as a complication of COVID-19 and is an important component of Post-Acute Sequelae of COVID-19 (PASC or long COVID). PASC shares many overlapping clinical features with other infection-associated chronic illnesses including Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Post-Treatment Lyme Disease Syndrome (PTLDS), suggesting that they may share common underlying mechani...
Source: Frontiers in Neurology - February 8, 2024 Category: Neurology Source Type: research

Evolutionary dynamics and geographical dispersal of Borrelia lusitaniae
ConclusionThe results of this study can provide beneficial information about the potential for further spread of B. lusitaniae in Europe and North Africa and estimation of necessity for the development of strategies to monitor and control Lyme borreliosis. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - February 6, 2024 Category: Microbiology Source Type: research

Morgellons disease: a narrative review
AbstractMorgellons disease is characterized by the persistent delusion of skin infestation, ultimately inflicting wounds and impairing quality of life. There is insufficient and conflicting research pertaining to this condition, imposing challenges on clinicians in understanding, diagnosing, and treating it. In this review, we summarize the available literature on Morgellons disease including its historical evolution, epidemiology, proposed pathophysiology, underlying structural and functional brain pathologies, typical and atypical clinical presentations, diagnosis, and treatment. A comprehensive review of the literature ...
Source: Neurological Sciences - February 6, 2024 Category: Neurology Source Type: research