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Evolving role of viadisc for chronic low back and discogenic pain: a narrative review
Expert Opin Emerg Drugs. 2024 Apr 11. doi: 10.1080/14728214.2024.2339912. Online ahead of print.ABSTRACTINTRODUCTION: Chronic lower back pain is a leading cause of disability and healthcare spending worldwide. Discogenic pain, pain originating from the intervertebral disk, is a common etiology of chronic lower back pain. Currently, accepted treatments for chronic discogenic pain focus only on the management of symptoms, such as pain. There are no approved treatments that stop or reverse degenerating intervertebral discs. Biologic therapies promoting disc regeneration have been developed to expand treatment options. VIADISC...
Source: Expert Opinion on Emerging Drugs - April 11, 2024 Category: Drugs & Pharmacology Authors: Jack K Tolson Robert L Menuet Gianni H Ly Benjamin A Chanes Elizabeth A Bryan Saurabh Kataria Julian Kim Shahab Ahmadzadeh Sahar Shekoohi Alan D Kaye Source Type: research

Manual rolling load and low back pain among workers in Japan: A cross-sectional study
CONCLUSIONS: Rolling weights between 40 and 400 kg could place a high stress on the lower back. Implementation of the HSE recommendations regarding rolling load in Japan should be carefully considered.PMID:38604161 | DOI:10.1093/joccuh/uiae015 (Source: Journal of Occupational Health)
Source: Journal of Occupational Health - April 11, 2024 Category: Occupational Health Authors: Kazuyuki Iwakiri Takeshi Sasaki Tanghuizi Du Keiichi Miki Fuyuki Oyama Source Type: research

Validity and reliability of Japanese version of MAPO index for assessing manual patient handling in nursing homes
CONCLUSIONS: High inter-rater reliability and J-MAPO risk levels were associated with LBP. Therefore, our results suggest that the J-MAPO is a useful risk assessment tool for LBP in Japanese nursing homes.PMID:38604159 | DOI:10.1093/joccuh/uiae016 (Source: Journal of Occupational Health)
Source: Journal of Occupational Health - April 11, 2024 Category: Occupational Health Authors: Naomichi Tani Fumiko Ichikawa Susumu Oda Olga Menoni Marco Tasso Kazuyuki Iwakiri Masaharu Kumashiro Takeshi Ebara Yasuhiro Tsutsui Source Type: research

Physician Empathy and Chronic Pain Outcomes
CONCLUSIONS AND RELEVANCE: In this cohort study of adult patients with chronic pain, physician empathy was associated with better outcomes over 12 months. Greater efforts to cultivate and improve physician empathy appear warranted.PMID:38602675 | DOI:10.1001/jamanetworkopen.2024.6026 (Source: Pain Physician)
Source: Pain Physician - April 11, 2024 Category: Anesthesiology Authors: John C Licciardone Yen Tran Khang Ngo David Toledo Navya Peddireddy Subhash Aryal Source Type: research

How low back pain is managed-a mixed methods study in 32 countries. Part 2 of Low Back Pain in Low- and Middle-Income Countries Series
J Orthop Sports Phys Ther. 2024 Apr 11:1-42. doi: 10.2519/jospt.2024.12406. Online ahead of print.ABSTRACTBACKGROUND: The Lancet Series of Low Back Pain (LBP) highlighted the lack of LBP data from low- and middle-income countries (LMICs). The study aimed to describe (1) what LBP care is currently delivered in LMICs, and (2) how that care is delivered. METHODS: An online mixed-methods study. A Consortium for LBP in LMICs (n=65) was developed with an expert panel of leading LBP researchers (>2 publications on LBP) and multidisciplinary clinicians and patient partners with five years of clinical/lived LBP experience in LMI...
Source: Physical Therapy - April 11, 2024 Category: Physiotherapy Authors: Saurab Sharma Anupa Pathak Romy Parker Leonardo Oliveira Pena Costa Babita Ghai Chinonso Igwesi-Chidobe Prawit Janwantanakul Fabianna Resende de Jesus-Moraleida Mulugeta Bayisa Chala Mohammadreza Pourahmadi Andrew M Briggs Edward Gorgon Clare L Ardern Kar Source Type: research

Physician Empathy and Chronic Pain Outcomes
CONCLUSIONS AND RELEVANCE: In this cohort study of adult patients with chronic pain, physician empathy was associated with better outcomes over 12 months. Greater efforts to cultivate and improve physician empathy appear warranted.PMID:38602675 | PMC:PMC11009829 | DOI:10.1001/jamanetworkopen.2024.6026 (Source: Pain Physician)
Source: Pain Physician - April 11, 2024 Category: Anesthesiology Authors: John C Licciardone Yen Tran Khang Ngo David Toledo Navya Peddireddy Subhash Aryal Source Type: research

SP1/CTR1 ‐mediated oxidative stress‐induced cuproptosis in intervertebral disc degeneration
This study highlights the importance of cuproptosis in IDD progression and provides a promising therapeutic target for IDD treatment. (Source: BioFactors)
Source: BioFactors - April 11, 2024 Category: Biochemistry Authors: Xuanzuo Chen, Kanglu Li, Yan Xiao, Wei Wu, Hui Lin, Xiangcheng Qing, Shuo Tian, Sheng Liu, Shiqing Feng, Baichuan Wang, Zengwu Shao, Yizhong Peng Tags: RESEARCH ARTICLE Source Type: research

Reactive Oxygen Species Induced Upregulation of TRPV1 in Dorsal Root Ganglia Results in Low Back Pain in Rats
(Source: Journal of Inflammation Research)
Source: Journal of Inflammation Research - April 11, 2024 Category: Allergy & Immunology Tags: Journal of Inflammation Research Source Type: research

The Fremantle Back Awareness Questionnaire: cross-cultural adaptation, reliability, and validity of the Italian version in people with chronic low back pain
There is evidence to suggest that assessing back-specific altered self-perception may be useful when seeking to understand and manage low back pain (LBP). The Fremantle Back Awareness Questionnaire (FreBAQ) is... (Source: BMC Musculoskeletal Disorders)
Source: BMC Musculoskeletal Disorders - April 11, 2024 Category: Orthopaedics Authors: Marco Monticone, Carolina Maurandi, Elisa Porcu, Federico Arippa, Benedict M. Wand and Giorgio Corona Tags: Research Source Type: research