Improvement in right heart function following kidney transplantation in esrd patients: insights from speckle tracking echocardiography analysis
This study aimed to evaluate the effects of KTx on the right heart chambers in ESRD patients. 57 adult KTx candidates were enrolled in this prospective longitudinal study, while 49 of them were included in the final assessment. Patients underwent a comprehensive cardiac assessment, including conventional echocardiography, speckle tracking echocardiography, and three-dimensional heart modeling both before and after surgery. Echocardiographic assessments showed significant increases in right ventricular (RV) ejection fraction, RV fractional area change (RVFAC), tricuspid annular plain systolic excursion, RV fractional shorte...
Source: The International Journal of Cardiovascular Imaging - April 23, 2024 Category: Radiology Source Type: research
Mesenchymal stem cells promote ovarian reconstruction in mice
CONCLUSIONS: The presence of BM-MSCs in the artificial ovary was found to promote the survival of ovarian cells, as well as facilitate follicle formation and development. Since the cells didn't proliferate in the reconstituted ovary, this discovery suggests a potential new and safe method for the application of MSCs in clinical fertility preservation by enhancing the success rate of cryo-thawed ovarian tissues after transplantation.PMID:38650029 | DOI:10.1186/s13287-024-03718-z (Source: Cell Research)
Source: Cell Research - April 22, 2024 Category: Cytology Authors: Jiazhao Li Haonan Fan Wei Liu Jing Zhang Yue Xiao Yue Peng Weijie Yang Wenwen Liu Yuanlin He Lianju Qin Xiang Ma Jing Li Source Type: research
Impaired kidney function: supporting the safe use of medicines for patients
This article provides an overview of the effects of impaired kidney function on pharmacokinetics and the importance of accurate drug dose adjustments for patients with related conditions. It also discusses various aspects of medicines use in patients with AKI, the pharmacological management of patients with CKD and the use of immunosuppressive therapy in patients who have had a kidney transplant. The authors consider the role of the nurse in ensuring safe medicines use for patients with impaired kidney function throughout the article.PMID:38646689 | DOI:10.7748/ns.2024.e12075 (Source: Nursing Standard)
Source: Nursing Standard - April 22, 2024 Category: Nursing Authors: Kathrine Parker Janette Chu Source Type: research
Drug-drug interaction between tacrolimus and caspofungin in Chinese kidney transplant patients with different < em > CYP3A5 < /em > genotypes
CONCLUSION: Co-administration of caspofungin reduced tacrolimus blood levels and elevated the required daily dose of tacrolimus. In CYP3A5 non-expressers, co-administration of caspofungin had a significant effect on tacrolimus C0/D values. An approximate 10% increase in the weight-adjusted daily dose of tacrolimus in CYP3A5 non-expressers is recommended to ensure the safety of tacrolimus administration.PMID:38646424 | PMC:PMC11027596 | DOI:10.1177/20420986241243165 (Source: Adv Data)
Source: Adv Data - April 22, 2024 Category: Epidemiology Authors: Yundi Zhang Bowen Shen Yue Li Huiying Zong Xiaoming Zhang Xiaohong Cao Fengxi Liu Yan Li Source Type: research
Comparison of skin cancer risk between renal transplant recipients and patients with glomerular diseases in rural Queensland
CONCLUSION: In patients with a high risk of NMSC, reducing skin cancer risk should be considered in conjunction with the optimisation of treatment.PMID:38646861 | DOI:10.1111/ajr.13081 (Source: The Australian Journal of Rural Health)
Source: The Australian Journal of Rural Health - April 22, 2024 Category: Rural Health Authors: Zaw Thet Alfred King-Yin Lam Shu-Kay Ng Soe Yu Aung Thin Han Dwarakanathan Ranganathan Stephanie Newsham Jennifer Borg Christine Pepito Tien K Khoo Source Type: research
From the Clinical to the Bench: Exploring the Insulin Modulation Effects of Tacrolimus and Belatacept
This study investigates whether the observed effects on PTD stem solely from CNI withdrawal or if belatacept influences PTD independently. The study assessed the impact of tacrolimus and belatacept on insulin secretion in MIN6 cells (a beta cell line) and rat islets. Tacrolimus and belatacept were administered to the cells and islets, followed by assessments of cell viability and insulin secretion. Tacrolimus impaired insulin secretion without affecting cell viability, while belatacept showed no detrimental effects on either parameter. These findings support clinical observations of improved HbA1c upon switching from tacro...
Source: Cell Transplantation - April 22, 2024 Category: Cytology Authors: Quentin Perrier C écile Cottet-Rouselle Marine de-Beaumont Johan Noble Sandrine Lablanche Source Type: research
Impaired kidney function: supporting the safe use of medicines for patients
This article provides an overview of the effects of impaired kidney function on pharmacokinetics and the importance of accurate drug dose adjustments for patients with related conditions. It also discusses various aspects of medicines use in patients with AKI, the pharmacological management of patients with CKD and the use of immunosuppressive therapy in patients who have had a kidney transplant. The authors consider the role of the nurse in ensuring safe medicines use for patients with impaired kidney function throughout the article.PMID:38646689 | DOI:10.7748/ns.2024.e12075 (Source: Nursing Standard)
Source: Nursing Standard - April 22, 2024 Category: Nursing Authors: Kathrine Parker Janette Chu Source Type: research
Comparison of skin cancer risk between renal transplant recipients and patients with glomerular diseases in rural Queensland
CONCLUSION: In patients with a high risk of NMSC, reducing skin cancer risk should be considered in conjunction with the optimisation of treatment.PMID:38646861 | DOI:10.1111/ajr.13081 (Source: The Australian Journal of Rural Health)
Source: The Australian Journal of Rural Health - April 22, 2024 Category: Rural Health Authors: Zaw Thet Alfred King-Yin Lam Shu-Kay Ng Soe Yu Aung Thin Han Dwarakanathan Ranganathan Stephanie Newsham Jennifer Borg Christine Pepito Tien K Khoo Source Type: research
Impaired kidney function: supporting the safe use of medicines for patients
This article provides an overview of the effects of impaired kidney function on pharmacokinetics and the importance of accurate drug dose adjustments for patients with related conditions. It also discusses various aspects of medicines use in patients with AKI, the pharmacological management of patients with CKD and the use of immunosuppressive therapy in patients who have had a kidney transplant. The authors consider the role of the nurse in ensuring safe medicines use for patients with impaired kidney function throughout the article.PMID:38646689 | DOI:10.7748/ns.2024.e12075 (Source: Nursing Standard)
Source: Nursing Standard - April 22, 2024 Category: Nursing Authors: Kathrine Parker Janette Chu Source Type: research
Comparison of skin cancer risk between renal transplant recipients and patients with glomerular diseases in rural Queensland
CONCLUSION: In patients with a high risk of NMSC, reducing skin cancer risk should be considered in conjunction with the optimisation of treatment.PMID:38646861 | DOI:10.1111/ajr.13081 (Source: The Australian Journal of Rural Health)
Source: The Australian Journal of Rural Health - April 22, 2024 Category: Rural Health Authors: Zaw Thet Alfred King-Yin Lam Shu-Kay Ng Soe Yu Aung Thin Han Dwarakanathan Ranganathan Stephanie Newsham Jennifer Borg Christine Pepito Tien K Khoo Source Type: research
Impaired kidney function: supporting the safe use of medicines for patients
This article provides an overview of the effects of impaired kidney function on pharmacokinetics and the importance of accurate drug dose adjustments for patients with related conditions. It also discusses various aspects of medicines use in patients with AKI, the pharmacological management of patients with CKD and the use of immunosuppressive therapy in patients who have had a kidney transplant. The authors consider the role of the nurse in ensuring safe medicines use for patients with impaired kidney function throughout the article.PMID:38646689 | DOI:10.7748/ns.2024.e12075 (Source: Nursing Standard)
Source: Nursing Standard - April 22, 2024 Category: Nursing Authors: Kathrine Parker Janette Chu Source Type: research
Comparison of skin cancer risk between renal transplant recipients and patients with glomerular diseases in rural Queensland
CONCLUSION: In patients with a high risk of NMSC, reducing skin cancer risk should be considered in conjunction with the optimisation of treatment.PMID:38646861 | DOI:10.1111/ajr.13081 (Source: The Australian Journal of Rural Health)
Source: The Australian Journal of Rural Health - April 22, 2024 Category: Rural Health Authors: Zaw Thet Alfred King-Yin Lam Shu-Kay Ng Soe Yu Aung Thin Han Dwarakanathan Ranganathan Stephanie Newsham Jennifer Borg Christine Pepito Tien K Khoo Source Type: research
Impaired kidney function: supporting the safe use of medicines for patients
This article provides an overview of the effects of impaired kidney function on pharmacokinetics and the importance of accurate drug dose adjustments for patients with related conditions. It also discusses various aspects of medicines use in patients with AKI, the pharmacological management of patients with CKD and the use of immunosuppressive therapy in patients who have had a kidney transplant. The authors consider the role of the nurse in ensuring safe medicines use for patients with impaired kidney function throughout the article.PMID:38646689 | DOI:10.7748/ns.2024.e12075 (Source: Nursing Standard)
Source: Nursing Standard - April 22, 2024 Category: Nursing Authors: Kathrine Parker Janette Chu Source Type: research
Comparison of skin cancer risk between renal transplant recipients and patients with glomerular diseases in rural Queensland
CONCLUSION: In patients with a high risk of NMSC, reducing skin cancer risk should be considered in conjunction with the optimisation of treatment.PMID:38646861 | DOI:10.1111/ajr.13081 (Source: The Australian Journal of Rural Health)
Source: The Australian Journal of Rural Health - April 22, 2024 Category: Rural Health Authors: Zaw Thet Alfred King-Yin Lam Shu-Kay Ng Soe Yu Aung Thin Han Dwarakanathan Ranganathan Stephanie Newsham Jennifer Borg Christine Pepito Tien K Khoo Source Type: research
Percutaneous Nephrolithotomy for De Novo Urolithiasis After Kidney Transplantation: A Systematic Review of the Literature
Journal of Endourology, Ahead of Print. (Source: Journal of Endourology)
Source: Journal of Endourology - April 22, 2024 Category: Urology & Nephrology Authors: Clara Cerrato Victoria Jahrreiss Carlotta Nedbal Francesco Ripa Vincenzo De Marco Manoj Monga B.M.Z. Hameed Peter Kronenberg Amelia Pietropaolo Nithesh Naik Bhaskar K. Somani Source Type: research
