Mesenchymal stem cells promote ovarian reconstruction in mice

CONCLUSIONS: The presence of BM-MSCs in the artificial ovary was found to promote the survival of ovarian cells, as well as facilitate follicle formation and development. Since the cells didn't proliferate in the reconstituted ovary, this discovery suggests a potential new and safe method for the application of MSCs in clinical fertility preservation by enhancing the success rate of cryo-thawed ovarian tissues after transplantation.PMID:38650029 | DOI:10.1186/s13287-024-03718-z

Source: Cell Research - April 22, 2024 Category: Cytology Authors: Jiazhao Li Haonan Fan Wei Liu Jing Zhang Yue Xiao Yue Peng Weijie Yang Wenwen Liu Yuanlin He Lianju Qin Xiang Ma Jing Li Source Type: research