First-Ever Porcine Kidney Transplant Patient Discharged
An early rejection required treatment, but the patient in the groundbreaking case is reported to be " doing fine " ; longer-term outcomes are being watched. (Source: Medscape Transplantation Podcast)
Source: Medscape Transplantation Podcast - April 5, 2024 Category: Transplant Surgery Authors: Medscape 210869 Source Type: podcasts
US Surgeons Perform First Pig-to-human Kidney Transplant
A 62-year-man with end-stage renal disease has become the first human to receive a new kidney from a genetically modified pig, doctors from Massachusetts General Hospital in... (Source: Medscape Transplantation Podcast)
Source: Medscape Transplantation Podcast - March 21, 2024 Category: Transplant Surgery Authors: Medscape 210869 Source Type: podcasts
Dialysis Facility Performance and Social Risk in the First Year of the ESRD Treatment Choices Model
Dialysis facilities in the US are financially rewarded for higher rates of home dialysis and kidney transplant, but facilities that serve patients with high social risk might have a harder time meeting these goals. JAMA Associate Editor Karen E. Joynt Maddox, MD, MPH, speaks with Amal N. Trivedi, MD, MPH, of Brown University, about how this plays out under the ESRD Treatment Choices Model. Related Content: Social Risk and Dialysis Facility Performance in the First Year of the ESRD Treatment Choices Model (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - January 9, 2024 Category: General Medicine Authors: JAMA Network Source Type: podcasts
Gene edits move pig organs closer to human transplantation
In this episode:00:46 Engineered pig kidneys show transplantation promiseKidneys from genetically-engineered miniature pigs have been transplanted into non-human primates, in some cases keeping the animals alive for more than a year. Using CRISPR, a team made dozens of edits to the pig genome to prevent the monkeys’ immune system from attacking the organs. They also removed pig retrovirus genes that could represent an infection risk. These steps are necessary if pig organs are to be used in human transplants, something many clinicians and researchers think will be needed to overcome a critical shortage of organs for tran...
Source: Nature Podcast - October 11, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts
Are interventions for fatigue effective among people with kidney failure requiring dialysis?
Alongside their reviews on treatments for chronic kidney disease, the Cochrane Kidney and Transplant Group produce reviews for interventions that might help with its consequences. These were added to in August 2023 with a new review of ways to help manage the fatigue experienced by people requiring dialysis. Here ' s lead author, Patrizia Natale from the University of Sydney in Australia, to tell us about the review. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - October 10, 2023 Category: General Medicine Authors: Cochrane Source Type: podcasts
CMV Prophylaxis in Kidney Transplant, US Maternal Mortality, Diabetic Foot Ulcers, and more
Editor’s Summary by Anne Rentoumis Cappola, MD, ScM, Associate Editor of JAMA, the Journal of the American Medical Association, for the July 3, 2023, issue. Related Content: Audio Highlights (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - July 3, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts
Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus Disease in High-Risk Kidney Transplant Recipients
Valganciclovir is standard cytomegalovirus (CMV) prophylaxis in high-risk kidney transplant recipients, but its use is limited by myelosuppression. JAMA Deputy Editor Preeti Malani, MD, MSJ, interviews Ajit Limaye, MD, from the University of Washington, about a multinational randomized trial of letermovir vs valganciclovir for CMV prevention in CMV-negative patients receiving a kidney from a CMV-positive donor. Related Content: Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-Risk Kidney Transplant Recipients (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - July 3, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts
JAMA Internal Medicine : Association of Pretransplant Coronary Heart Disease Testing With Early Kidney Transplant Outcomes
Interview with Xingxing S. Cheng, MD, MS, author of Association of Pretransplant Coronary Heart Disease Testing With Early Kidney Transplant Outcomes. Hosted by Rita Redberg, MD. Related Content: Association of Pretransplant Coronary Heart Disease Testing With Early Kidney Transplant Outcomes (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - January 3, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
SCCM Pod-463 CCM: Clazakizumab for COVID-19: Friend or Foe?
Clazakizumab is a monoclonal antibody against human interleukin-6 that may benefit patients hospitalized with severe or critical COVID-19 accompanied by hyperinflammation. Although not yet FDA approved, clinical trials of clazakizumab for treatment of COVID-19 are under way worldwide. Samantha Gambles Farr, MSN, NP-C, CCRN, RNFA, is joined by Bonnie E. Lonze, MD, PhD, to discuss the article, A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation, published in the September 2022 issue of Critical Care Medicine. Dr. Lonze is a faculty transplant sur...
Source: SCCM PodCast - iCritical Care - December 21, 2022 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts
SCCMPod-463 CCM: Clazakizumab for COVID-19: Friend or Foe?
Clazakizumab is a monoclonal antibody against human interleukin-6 that may benefit patients hospitalized with severe or critical COVID-19 accompanied by hyperinflammation. Although not yet FDA approved, clinical trials of clazakizumab for treatment of COVID-19 are under way worldwide. Samantha Gambles Farr, MSN, NP-C, CCRN, RNFA, is joined by Bonnie E. Lonze, MD, PhD, to discuss the article, A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation, published in the September 2022 issue of Critical Care Medicine. Dr. Lonze is a faculty transplant sur...
Source: SCCM PodCast - iCritical Care - October 6, 2022 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts
TWiV 905: COVID-19 clinical update #117 with Dr. Daniel Griffin
In COVID-19 clinical update #117, Dr. Griffin discusses duration of virus shedding, association between pre-exposure to steroids and infection outcome, post-infection subtypes, rehabilitation for post-acute infection, Tixagevimab/Cilgavimab for infection prevention, antibody prophylaxis and vaccination in kidney transplant recipients, remdesivir and bebtelovimab fact sheets for providers, the updated guidelines on treatment with Famotidine, Paxlovid rebound symptom characterizations, antigen test positivity duration, viral dynamics of variants and isolation, association of inflammation in CS fluid, and transmission dynami...
Source: This Week in Virology - MP3 Edition - June 4, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
X-ray analysis hints at answers to fossil mystery
00:45 The puzzle of PalaeospondylusOver a hundred years ago, archaeologists discovered fossils of the aquatic animal Palaeospondylus. But since then researchers have been unable to place where this animal sits on the tree of life. Now, new analysis of Palaeospondylus’s anatomy might help to solve this mystery.Research article: Hirasawa et al.News and Views: Clues to the identity of the fossil fish Palaeospondylus08:18 Research HighlightsA strong, silk-based version of mother of pearl, and the parrots that use their heads when climbing.Research Highlight: Silk imitates mother of pearl for a tough, eco-friendly materialRes...
Source: Nature Podcast - May 25, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts
JAMA Surgery : Evaluation of Community-Level Vulnerability and Racial Disparities in Living Donor Kidney Transplant
Interview with Jayme E. Locke, MD MPH, and Alixandra Cozette Killian, MD MPH, authors of Evaluation of Community-Level Vulnerability and Racial Disparities in Living Donor Kidney Transplant (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - September 15, 2021 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
TWiV 787: COVID-19 clinical update #73 with Dr. Daniel Griffin
In COVID-19 clinical update #73, Daniel Griffin reviews updated mask guidance from CDC, infections in public school district employees, effectiveness of vaccines against delta variant, antibody response after third vaccine dose in kidney transplant recipients, protection afforded by mRNA vaccines fully vaccinated people with and without prior infections, correlates of protection in nonhuman primates, lack of effectiveness of doxycycline, neurological manifestations of COVID-19, and infection in vaccinated health care workers. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, ...
Source: This Week in Virology - MP3 Edition - July 31, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
