Tetrazine ligation for chemical proteomics
Determining small molecule —target protein interaction is essential for the chemical proteomics. One of the most important keys to explore biological system in chemical proteomics field is finding first-class m... (Source: Proteome Science)
Source: Proteome Science - June 26, 2017 Category: Bioinformatics Authors: Kyungtae Kang, Jongmin Park and Eunha Kim Source Type: research
Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)
Protein-protein interactions (PPIs) trigger a wide range of biological signaling pathways that are crucial for biomedical research and drug discovery. Various techniques have been used to study specific protei... (Source: Proteome Science)
Source: Proteome Science - June 24, 2017 Category: Bioinformatics Authors: Dhiraj P. Murale, Seong Cheol Hong, Md. Mamunul Haque and Jun-Seok Lee Source Type: research
Thermal proteome profiling: unbiased assessment of protein state through heat-induced stability changes
In recent years, phenotypic-based screens have become increasingly popular in drug discovery. A major challenge of this approach is that it does not provide information about the mechanism of action of the hit... (Source: Proteome Science)
Source: Proteome Science - June 24, 2017 Category: Bioinformatics Authors: Andr é Mateus, Tomi A. Määttä and Mikhail M. Savitski Source Type: research
The hepatocyte proteome in organotypic rat liver models and the influence of the local microenvironment
Liver models that closely mimic the in vivo microenvironment are useful for understanding liver functions, capabilities, and intercellular communication processes. Three-dimensional (3D) liver models assembled... (Source: Proteome Science)
Source: Proteome Science - June 20, 2017 Category: Bioinformatics Authors: Lucas T. Vu, Sophia M. Orbach, W. Keith Ray, Margaret E. Cassin, Padmavathy Rajagopalan and Richard F. Helm Source Type: research
Characterisation of the circulating acellular proteome of healthy sheep using LC-MS/MS-based proteomics analysis of serum
Unlike humans, there is currently no publicly available reference mass spectrometry-based circulating acellular proteome data for sheep, limiting the analysis and interpretation of a range of physiological cha... (Source: Proteome Science)
Source: Proteome Science - June 10, 2017 Category: Bioinformatics Authors: Saul Chemonges, Rajesh Gupta, Paul C. Mills, Steven R. Kopp and Pawel Sadowski Source Type: research
The effect of microbial challenge on the intestinal proteome of broiler chickens
In poultry production intestinal health and function is paramount to achieving efficient feed utilisation and growth. Uncovering the localised molecular mechanisms that occur during the early and important per... (Source: Proteome Science)
Source: Proteome Science - May 30, 2017 Category: Bioinformatics Authors: Emily L. O ’Reilly, Richard J. Burchmore, Nicholas H. Sparks and P. David Eckersall Source Type: research
Water deficit mechanisms in perennial shrubs Cerasus humilis leaves revealed by physiological and proteomic analyses
Drought (Water deficit, WD) poses a serious threat to extensively economic losses of trees throughout the world. Chinese dwarf cherry (Cerasus humilis) is a good perennial plant for studying the physiological and... (Source: Proteome Science)
Source: Proteome Science - May 8, 2017 Category: Bioinformatics Authors: Zepeng Yin, Jing Ren, Lijuan Zhou, Lina Sun, Jiewan Wang, Yulong Liu and Xingshun Song Source Type: research
Merging clinical chemistry biomarker data with a COPD database - building a clinical infrastructure for proteomic studies
Data from biological samples and medical evaluations plays an essential part in clinical decision making. This data is equally important in clinical studies and it is critical to have an infrastructure that en... (Source: Proteome Science)
Source: Proteome Science - April 21, 2017 Category: Bioinformatics Authors: Jonatan Eriksson, Simone Andersson, Roger Appelqvist, Elisabet Wieslander, Mikael Truedsson, May Bugge, Johan Malm, Magnus Dahlb äck, Bo Andersson, Thomas E. Fehniger and György Marko-Varga Source Type: research
Proteomic profiling of HBV infected liver biopsies with different fibrotic stages
This study aims to enlighten pathways associated with ... (Source: Proteome Science)
Source: Proteome Science - April 20, 2017 Category: Bioinformatics Authors: Seyma Katrinli, Kamil Ozdil, Abdurrahman Sahin, Oguzhan Ozturk, Gozde Kir, Ahmet Tarik Baykal, Emel Akgun, Omer Sinan Sarac, Mehmet Sokmen, H. Levent Do ğanay and Gizem Dinler Doğanay Source Type: research
Disulfide proteomics of rice cultured cells in response to OsRacl and probenazole-related immune signaling pathway in rice
Reactive oxygen species (ROS) production is an early event in the immune response of plants. ROS production affects the redox-based modification of cysteine residues in redox proteins, which contribute to prot... (Source: Proteome Science)
Source: Proteome Science - April 13, 2017 Category: Bioinformatics Authors: Kazuko Morino, Mayumi Kimizu and Masayuki Fujiwara Source Type: research
Proteomic analysis of microparticles isolated from malaria positive blood samples
Malaria continues to be a great public health concern due to the significant mortality and morbidity associated with the disease especially in developing countries. Microparticles (MPs), also called plasma mem... (Source: Proteome Science)
Source: Proteome Science - March 24, 2017 Category: Bioinformatics Authors: Samuel Antwi-Baffour, Jonathan Kofi Adjei, Francis Agyemang-Yeboah, Max Annani-Akollor, Ransford Kyeremeh, George Awuku Asare and Ben Gyan Source Type: research
