Exosome proteomes reveal glycolysis-related enzyme enrichment in primary canine mammary gland tumor compared to metastases
Numerous evidence has highlighted the differences between primary tumors and metastases. Nonetheless, the differences in exosomal proteins derived from primary tumor and metastases remain elusive. Here, we aim... (Source: Proteome Science)
Source: Proteome Science - February 28, 2024 Category: Bioinformatics Authors: Hui-Su Kim and Je-Yoel Cho Tags: Research Source Type: research
Comparative proteomics reveals different protein expression in platelets in patients with alcoholic liver cirrhosis
The role of platelets in disease progression as well as the function of platelets as part of the haemostatic and immunological system in patients with liver cirrhosis is only incompletely understood. This is p... (Source: Proteome Science)
Source: Proteome Science - January 26, 2024 Category: Bioinformatics Authors: Nima Haji Begli, Cora Freund, Karl-Heinz Weiss, Daniel Gotthardt and Andreas Wannhoff Tags: Research Source Type: research
Methionine enkephalin (MENK) protected macrophages from ferroptosis by downregulating HMOX1 and ferritin
The aim of this work was to investigate the immunological effect of MENK by analyzing the protein spectrum and bioinformatics of macrophage RAW264.7, and to explore the relationship between macrophage and ferr... (Source: Proteome Science)
Source: Proteome Science - January 20, 2024 Category: Bioinformatics Authors: Jing Tian, Wenrui Fu, Zifeng Xie, Yuanlong Zhao, Haochen Yang and Jiafan Zhao Tags: Research Source Type: research
Proteomic profile of tepary bean seed storage proteins in germination with low water potential
Tepary bean (Phaseolus acutifolius A. Gray) is one of the five species domesticated from the genus Phaseolus with genetic resistance to biotic and abiotic stress. To understand the mechanisms underlying drought r... (Source: Proteome Science)
Source: Proteome Science - January 9, 2024 Category: Bioinformatics Authors: Daniel Padilla-Chac ón, Laura Campos-Patiño, Cecilia B. Peña-Valdivia, Antonio García-Esteva, José Cruz Jiménez-Galindo and Jorge Luis Pizeno-García Tags: Research Source Type: research
Upregulation of S100A8 in peripheral blood mononuclear cells from patients with depression treated with SSRIs: a pilot study
Major depressive disorder (MDD) affects more than 350 million people worldwide, and there is currently no laboratory test to diagnose it. This pilot study aimed to identify potential biomarkers in peripheral b... (Source: Proteome Science)
Source: Proteome Science - December 4, 2023 Category: Bioinformatics Authors: Concepci ón Gamboa-Sánchez, Enrique Becerril-Villanueva, Samantha Alvarez-Herrera, Gabriela Leyva-Mascareño, Sandra L. González-López, Enrique Estudillo, Alberto E. Fernández-Molina, José Miguel Elizalde-Contreras, Eliel Ruiz-May, Aldo Segura-Cabre Tags: Research Source Type: research
Systematic proteomics profiling of lysine crotonylation of the lung at Pseudoglandular and Canalicular phases in human fetus
Lung tissue is an important organ of the fetus, and genomic research on its development has improved our understanding of the biology of this tissue. However, the proteomic research of developing fetal lung ti... (Source: Proteome Science)
Source: Proteome Science - December 1, 2023 Category: Bioinformatics Authors: Wei Wang, Wei Shi, Yinglan Wang, Yane Yang, Ping Li, Zhipeng Zeng, Wenlong Hu, Yumei Chen, Donge Tang and Yong Dai Tags: Research Source Type: research
TMT quantitative proteomics reveals key proteins relevant to microRNA-1-mediated regulation in osteoarthritis
Osteoarthritis (OA) is the second-commonest arthritis, but pathogenic and regulatory mechanisms underlying OA remain incompletely understood. Here, we aimed to identify the mechanisms associated with microRNA-... (Source: Proteome Science)
Source: Proteome Science - November 22, 2023 Category: Bioinformatics Authors: Pinpin Jiang, Dan Liang, Hang Wang, Raorao Zhou, Xianda Che, Linlin Cong, Penghua Li, Chunfang Wang, Wenjin Li, Xiaochun Wei and Pengcui Li Tags: Research Source Type: research
Label-free quantitative proteomic analysis of serum exosomes in mice with thoracic aortic aneurysm
Thoracic aortic aneurysm (TAA) is a cardiovascular disease with high morbidity and mortality. However, the causes and mechanisms of TAA are not fully understood. Serum exosomes from mice with TAA were used to ... (Source: Proteome Science)
Source: Proteome Science - October 24, 2023 Category: Bioinformatics Authors: Jia Xu, Jiacheng Liu, Yibai Qu, Linhui Jiang, Rongxin Liang, Bohai Li, Lei Li and Yong Jiang Tags: Research Source Type: research
Quantitative proteomics analysis reveals the key proteins related to semen quality in Niangya yaks
Proteins related to sperm motility and sperm morphology have an important impact on sperm function such as metabolism, motility and fertilisation etc. An understanding of the key proteins related to semen qual... (Source: Proteome Science)
Source: Proteome Science - October 24, 2023 Category: Bioinformatics Authors: Yaomei Wang, Yuchao Liu, Tingting Cao, Chunyuan Shi, Zili Ren and Yanling Zhao Tags: Research Source Type: research
Integrated proteome and malonylome analyses reveal the potential meaning of TLN1 and ACTB in end-stage renal disease
End-stage renal disease (ESRD) is a condition that is characterized by the loss of kidney function. ESRD patients suffer from various endothelial dysfunctions, inflammation, and immune system defects. Lysine m... (Source: Proteome Science)
Source: Proteome Science - October 13, 2023 Category: Bioinformatics Authors: Ruqi Tan, Dandan Li, Nan Hu, Jing Qiu, Zhipeng Zeng, Wanxia Cai, Yafang Zhong, Xinzhou Zhang, Pearl Pai, Kang Wang, Donge Tang and Yong Dai Tags: Research Source Type: research
Effects of µ-Conotoxin GIIIB on the cellular activity of mouse skeletal musculoblast: combined transcriptome and proteome analysis
This study was aimed to explored the cytotoxic effects of µ-CTX GIIIB on mouse s... (Source: Proteome Science)
Source: Proteome Science - October 12, 2023 Category: Bioinformatics Authors: Han-xi Wu, Pei-min He and Rui Jia Tags: Research Source Type: research
Proteomic analysis of neonatal mouse hearts shows PKA functions as a cardiomyocyte replication regulator
The ability of the adult mammalian heart to regenerate can save the cardiac muscle from a loss of function caused by injury. Cardiomyocyte regeneration is a key aspect of research for the treatment of cardiova... (Source: Proteome Science)
Source: Proteome Science - October 11, 2023 Category: Bioinformatics Authors: Lizhi Hu, Minglu Liang, Qin Jiang, Youming Jie, Long Chen and Fengxiao Zhang Tags: Research Source Type: research
Proteomic analysis of ceftazidime and meropenem-exposed Pseudomonas aeruginosa ATCC 9027
Pseudomonas aeruginosa is well known for its intrinsic ability to resist a wide range of antibiotics, thus complicates treatment. Thus, understanding the response of the pathogen to antibiotics is important for d... (Source: Proteome Science)
Source: Proteome Science - September 28, 2023 Category: Bioinformatics Authors: Hong Loan Ngo, Thuc Quyen Huynh, Nguyen Bao Vy Tran, Ngoc Hoa Binh Nguyen, Thi Hang Tong, Thi Truc Ly Trinh, Van Dung Nguyen, Prem Prakash Das, Teck Kwang Lim, Qingsong Lin and Thi Thu Hoai Nguyen Tags: Research Source Type: research
Insight into the underlying molecular mechanism of dilated cardiomyopathy through integrative analysis of data mining, iTRAQ-PRM proteomics and bioinformatics
DCM is a common cardiomyopathy worldwide, which is characterized by ventricular dilatation and systolic dysfunction. DCM is one of the most widespread diseases contributing to sudden death and heart failure. H... (Source: Proteome Science)
Source: Proteome Science - September 22, 2023 Category: Bioinformatics Authors: Hongli Xiong, Zhe Zheng, Congcong Zhao, Minzhu Zhao, Qi Wang, Peng Zhang, Yongguo Li, Ying Zhu, Shisheng Zhu and Jianbo Li Tags: Research Source Type: research
Analysis of differential membrane proteins related to matrix stiffness-mediated metformin resistance in hepatocellular carcinoma cells
Our previous work shows that increased matrix stiffness not only alters malignant characteristics of hepatocellular carcinoma (HCC) cells, but also attenuates metformin efficacy in treating HCC cells. Here, we... (Source: Proteome Science)
Source: Proteome Science - September 22, 2023 Category: Bioinformatics Authors: Xiangyu Gao, Jiali Qian, Yang Zhang, Heming Wang, Jiefeng Cui and Yehong Yang Tags: Research Source Type: research
