Correction: Heat stress-induced response of the proteomes of leaves from Salvia splendens vista and king
Upon publication of the article entitled "Heat stress-induced response of the proteomes of leaves from Salvia splendens Vista and King" [1] the authors recognised that Dr Heng-Mu Zhang had been omitted from the author list.The co-authors would like to apologise for this omission. All authors have agreed to the addition of Dr Hen-Mu Zhang to the revised author list as shown above, for his provision of the original raw experimental materials, contribution to the design of the experimental procedure and quantitative experiments of the plant physiology and biochemistry index.References1. Liu H, Shen G, Fang X, Fu Q, Huang K, C...
Source: Proteome Science - July 25, 2013 Category: Bioinformatics Authors: Hui LiuGuozheng ShenXianping FangQiaojuan FuKangkang HuangYi ChenHong YuHengMu ZhangYun ZhaoLe ZhangLiang JinSonglin Ruan Source Type: research
Erratum to: Heat stress-induced response of the proteomes of leaves from Salvia splendens vista and king
(Source: Proteome Science)
Source: Proteome Science - July 25, 2013 Category: Bioinformatics Authors: Hui Liu, Guozheng Shen, Xianping Fang, Qiaojuan Fu, Kangkang Huang, Yi Chen, Hong Yu, HengMu Zhang, Yun Zhao, Le Zhang, Liang Jin and Songlin Ruan Source Type: research
A note on protein expression changes in chicken breast muscle in response to time in transit before slaughtering
Aims of the research were to devise a proteome map of the chicken Pectoralis superficialis muscle, as resolved by two-dimensional gel electrophoresis, and to characterize protein expression changes in the soluble protein fraction in commercial conditions due to age and to time in transit before slaughtering. Broilers were reared under commercial conditions until they reached a mean 1.8 kg and 36 d, or 2.6 kg and 46 d of age. Transport to the slaughterhouse took 90 or 220 minutes. Transport-induced stress was assessed from blood metabolites and leukocyte cell counts, revealing significant changes in albumin, glucose and tri...
Source: Proteome Science - July 24, 2013 Category: Bioinformatics Authors: Enrico ZanettiAntonio MasiMicaela PivatoSerena TolinAnna TrentinCem GulerServet YalçinMartino Cassandro Source Type: research
A new type of protein chip to detect hepatocellular carcinoma-related autoimmune antibodies in the sera of hepatitis C virus-positive patients
Conclusion:
This protein chip system may have useful properties to capture a specific set of antibodies for predicting the onset of particular cancers such as HCC in HCV-infected individuals. (Source: Proteome Science)
Source: Proteome Science - July 19, 2013 Category: Bioinformatics Authors: Junko AkadaShuichi KameiAkane ItoMoe ItoTakao KitagawaHiroko FurumotoYukari KatoMichiko TamesaMotonari TakashimaMutsunori ShiraiHirofumi YamanoMasaaki OkaYasuhiro KuramitsuKazuyuki Nakamura Source Type: research
Proteomic analysis of the inhibitory effect of epigallocatechin gallate on lipid accumulation in human HepG2 cells
Conclusions:
From the proteomic analysis, we hypothesized that EGCG reduced cellular lipid accumulation in FFA-induced HepG2 cells through the activation of AMP-activated protein kinase (AMPK) resulting from the generation of reactive oxygen species (ROS). The induction of ROS may be a result of EGCG regulation of the antioxidant defense system. Activation of AMPK shifted some FFA toward oxidation, away from lipid and triglyceride storage, and suppressed hepatic gluconeogenesis. The findings of this study improve our understanding of the molecular mechanisms of inhibition of lipid accumulation by EGCG in HepG2 cells. (Sour...
Source: Proteome Science - July 18, 2013 Category: Bioinformatics Authors: Zhonghua LiuQin LiJianan HuangQionglin LiangYujun YanHaiyan LinWenjun XiaoYong LinSheng ZhangBin TanGuoan Luo Source Type: research
Identification of cellular proteome using two-dimensional difference gel electrophoresis in ST cells infected with transmissible gastroenteritis coronavirus
Conclusions:
To our knowledge, we have performed the first analysis of the proteomic changes in host cell during TGEV infection. 17 altered cellular proteins that differentially expressed in TGEV infection were identified. The present study provides protein-related information that should be useful for understanding the host cell response to TGEV infection and the underlying mechanism of TGEV replication and pathogenicity. (Source: Proteome Science)
Source: Proteome Science - July 16, 2013 Category: Bioinformatics Authors: Xin ZhangHong-Yan ShiJian-Fei ChenDa ShiHong-Wu LangZhong-Tian WangLi Feng Source Type: research
Identification of Enolase 1 and Thrombospondin-1 as serum biomarkers in HBV hepatic fibrosis by proteomics
Hepatic fibrosis is an inevitable process in the progression of chronic HBV infection to hepatic cirrhosis, but its detailed mechanism is still unknown. Clinic serum biomarkers of HBV hepatic cirrhosis were scanned by proteomic methods. We used two-dimensional electrophoresis (2-DE) and Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF-MS) to separate and identify the proteins which were differentially expressed in the serum of patients with hepatic fibrosis compared to HBV carriers. We identified 27 differentially expressed proteins, of which 19 proteins were up-regulated and 8 protei...
Source: Proteome Science - July 11, 2013 Category: Bioinformatics Authors: Bin ZhangZi WangBin DengXiaoqiong WuJing LiuXueping Feng Source Type: research
Comparative secretome analysis of four isogenic Bacillus clausii probiotic strains
Conclusion:
This study shows, for the first time, differences in the secretome of the OC, SIN, NR and T B. clausii strains. These differences indicate that specific secretome features characterize each of the four strains despite their genotypic similarity. This could confer to the B. clausii strains specific probiotic functions associated with the differentially expressed proteins and indicate that they can cooperate as probiotics as the secretome components of each strain could contribute to the overall activity of a mixed probiotic preparation. (Source: Proteome Science)
Source: Proteome Science - July 1, 2013 Category: Bioinformatics Authors: Rosa LippolisRosa SicilianoMaria MazzeoAnna AbbresciaAntonio GnoniAnna SardanelliSergio Papa Source Type: research
Proteomic analyses of age related changes in A.BY/SnJ mouse hearts
Conclusion:
The current proteomics study discloses age dependent changes occurring in the hearts already in young mice of the strain A.BY/SnJ. Besides alterations in protein transport, we provide evidence that a decrease of ATP synthase in murine hearts starts already in the first months of life, leading to well-known low expression levels manifested in old mice thereby raising the possibility of reduced energy supply. In the first few months of murine life this seems to be compensated by an increased lipid metabolism. The functional alterations described should be considered during experimental setups in disease related s...
Source: Proteome Science - July 1, 2013 Category: Bioinformatics Authors: Krishnatej NishtalaTruong PhongLeif SteilMartina SauterManuela SalazarReinhard KandolfStephan FelixUwe VölkerKarin KlingelElke Hammer Source Type: research
Proteomic profiling for the identification of serum diagnostic biomarkers for abdominal and thoracic aortic aneurysms
Conclusions:
Taken together, our findings suggest that Kallistatin and alpha-2-macroglobulin are potential serum biomarkers for both AAA and TAA and TAA, respectively. (Source: Proteome Science)
Source: Proteome Science - June 27, 2013 Category: Bioinformatics Authors: Kazumi SatohTomoko ManiwaTeiji OdaKen-ichi Matsumoto Source Type: research
Nuclear proteome response to cell wall removal in rice (Oryza sativa)
Plant cells are routinely exposed to various pathogens and environmental stresses that cause cell wall perturbations. Little is known of the mechanisms that plant cells use to sense these disturbances and transduce corresponding signals to regulate cellular responses to maintain cell wall integrity. Previous studies in rice have shown that removal of the cell wall leads to substantial chromatin reorganization and histone modification changes concomitant with cell wall re-synthesis. But the genes and proteins that regulate these cellular responses are still largely unknown. Here we present an examination of the nuclear prot...
Source: Proteome Science - June 19, 2013 Category: Bioinformatics Authors: Hana MujahidFeng TanJian ZhangBabi NallamilliKen PendarvisZhaohua Peng Source Type: research
Heat stress¿induced response of the proteomes of leaves from Salvia splendens Vista and King
Conclusions:
Most of the identified proteins are involved in photosynthesis, metabolism, protein processing, or stress response, indicating that many different processes work together to establish a new cellular homeostasis in response to heat stress. (Source: Proteome Science)
Source: Proteome Science - June 18, 2013 Category: Bioinformatics Authors: Hui LiuGuozheng ShenXianping FangQiaojuan FuKangkang HuangYi ChenHong YuYun ZhaoLe ZhangLiang JinSonglin Ruan Source Type: research
Heat stress--induced response of the proteomes of leaves from Salvia splendens Vista and King
Conclusions:
Most of the identified proteins are involved in photosynthesis, metabolism, protein processing, or stress response, indicating that many different processes work together to establish a new cellular homeostasis in response to heat stress. (Source: Proteome Science)
Source: Proteome Science - June 18, 2013 Category: Bioinformatics Authors: Hui LiuGuozheng ShenXianping FangQiaojuan FuKangkang HuangYi ChenHong YuYun ZhaoLe ZhangLiang JinSonglin Ruan Source Type: research
Azacytidine induces necrosis of multiple myeloma cells through oxidative stress
Azacytidine is an inhibitor of DNA methyltransferase and is known to be an anti-leukemic agent to induce cancer cell apoptosis. In the present study, multiple myeloma cells were treated with azacytidine at clinically relevant concentrations to induce necrosis through oxidative stress. Necrotic myeloma cells exhibit unique characteristics, including enrichment of the cell-bound albumin and overexpression of endoplasmic reticulum (ER)- and mitochondrial-specific chaperones, which were not observed in other necrotic cells, including HUH-7, A2780, A549, and Hoc1a. Proteomic analysis shows that HSP60 is the most abundant up-reg...
Source: Proteome Science - June 13, 2013 Category: Bioinformatics Authors: Enbing TianHaiping TangRenhua XuChongdong LiuHaiteng DengQingtao Wang Source Type: research
Impact of pyrrolidine-bispyrrole DNA minor groove binding agents and chirality on global proteomic profile in Escherichia Coli
Conclusion:
The current results showed that the chiral PySSPy and PyRSPy impact on the proteomic profiling of E coli DH5alpha, implicating the importance of drug chirality on biological activities at the molecular level. (Source: Proteome Science)
Source: Proteome Science - May 23, 2013 Category: Bioinformatics Authors: Ya-ting YangChun-Yu LinJingyueh JengChi-Wi Ong Source Type: research
