Comparative proteome analysis of abdominal adipose tissues between fat and lean broilers
The molecular mechanism underlying broiler fat deposition is still poorly understood. (Source: Proteome Science)
Source: Proteome Science - September 1, 2016 Category: Bioinformatics Authors: Chun-Yan Wu, Yuan-Yuan Wu, Chun-Dong Liu, Yu-Xiang Wang, Wei Na, Ning Wang and Hui Li Source Type: research
Investigation of proteome changes in osteoclastogenesis in low serum culture system using quantitative proteomics
RAW 264.7 cells can differentiate into osteoclasts when cultured in medium supplemented with 1 % FBS. However, the proteomic changes in the development of RAW 264.7 cells into osteoclasts in low serum culture ... (Source: Proteome Science)
Source: Proteome Science - March 31, 2016 Category: Bioinformatics Authors: Qi Xiong, Lihai Zhang, Shaohua Zhan, Wei Ge and Peifu Tang Source Type: research
The association of plasma cystatin C proteoforms with diabetic chronic kidney disease
Cystatin C (CysC) is an endogenous cysteine protease inhibitor that can be used to assess the progression of kidney function. Recent studies demonstrate that CysC is a more specific indicator of glomerular fil... (Source: Proteome Science)
Source: Proteome Science - March 25, 2016 Category: Bioinformatics Authors: Hussein N. Yassine, Olgica Trenchevska, Zhiwei Dong, Yara Bashawri, Juraj Koska, Peter D. Reaven, Randall W. Nelson and Dobrin Nedelkov Source Type: research
Stathmin involvement in the maternal embryonic leucine zipper kinase pathway in glioblastoma
Maternal Embryonic Leucine Zipper Kinase (MELK) is a serine/threonine kinase involved in cell cycle, differentiation, proliferation, and apoptosis. These multiple features are consistent with it being a potent... (Source: Proteome Science)
Source: Proteome Science - March 11, 2016 Category: Bioinformatics Authors: Suely Kazue Nagahashi Marie, Sueli Mieko Oba-Shinjo, Roseli da Silva, Marcela Gimenez, Gisele Nunes Reis, Jean-Pierre Tassan, Jose Cesar Rosa and Miyuki Uno Source Type: research
Analysis of the immune response of human dendritic cells to Mycobacterium tuberculosis by quantitative proteomics
The cellular immune response for Mycobacterium tuberculosis (M. tuberculosis) infection remained incompletely understood. To uncover membrane proteins involved in this infection mechanism, an integrated approach ... (Source: Proteome Science)
Source: Proteome Science - March 8, 2016 Category: Bioinformatics Authors: Chiu-Ping Kuo, Kuo-Song Chang, Jue-Liang Hsu, I-Fang Tsai, Andrew Boyd Lin, Tsai-Yin Wei, Chien-Liang Wu and Yen-Ta Lu Source Type: research
Label-free proteomic methodology for the analysis of human kidney stone matrix composition
Kidney stone matrix protein composition is an important yet poorly understood aspect of nephrolithiasis. We hypothesized that this proteome is considerably more complex than previous reports have indicated and... (Source: Proteome Science)
Source: Proteome Science - February 27, 2016 Category: Bioinformatics Authors: Frank A. Witzmann, Andrew P. Evan, Fredric L. Coe, Elaine M. Worcester, James E. Lingeman and James C. Williams Source Type: research
Quantitative succinylome analysis in the liver of non-alcoholic fatty liver disease rat model
Non-alcoholic fatty liver disease (NAFLD) is a clinical frequent disease. However, its pathogenesis still needs further study, especially the mechanism at the molecular level. The recent identified novel prote... (Source: Proteome Science)
Source: Proteome Science - February 3, 2016 Category: Bioinformatics Authors: Yang Cheng, Tianlu Hou, Jian Ping, Gaofeng Chen and Jianjie Chen Source Type: research
Secretome analysis of rice suspension-cultured cells infected by Xanthomonas oryzae pv.oryza (Xoo)
Rice bacterial blight (BB) caused by Xanthomonas oryzae pv.oryzae (Xoo) is one of the most devastating bacterial diseases in rice-growing regions worldwide. The rice-Xoo interaction is a classical model for study... (Source: Proteome Science)
Source: Proteome Science - February 2, 2016 Category: Bioinformatics Authors: Xian Chen, Zhiping Deng, Chulang Yu, Chengqi Yan and Jianping Chen Source Type: research
Isolation and characterization of Bradykinin potentiating peptides from Agkistrodon bilineatus venom
Snake venom is a source of many pharmacologically important molecules. Agkistrodon bilineatus commonly known as Cantil, is spread over Central America particularly in Mexico and Costa Rica. From the venom of Agki... (Source: Proteome Science)
Source: Proteome Science - January 14, 2016 Category: Bioinformatics Authors: Aisha Munawar, Anum Zahid, Amr Negm, Ahmed Akrem, Patrick Spencer and Christian Betzel Source Type: research
Analysis of protein expression in periodontal pocket tissue: a preliminary study
The periodontal disease is caused by a set of inflammatory disorders characterized by periodontal pocket formation that lead to tooth loss if untreated. The proteomic profile and related molecular conditions o... (Source: Proteome Science)
Source: Proteome Science - December 30, 2015 Category: Bioinformatics Authors: Emanuela Monari, Aurora Cuoghi, Elisa Bellei, Stefania Bergamini, Andrea Lucchi, Aldo Tomasi, Pierpaolo Cortellini, Davide Zaffe and Carlo Bertoldi Source Type: research
Gender-specific effects of intrauterine growth restriction on the adipose tissue of adult rats: a proteomic approach
Intrauterine growth restriction (IUGR) may program metabolic alterations affecting physiological functions and lead to diseases in later life. The adipose tissue is an important organ influencing energy homeos... (Source: Proteome Science)
Source: Proteome Science - December 2, 2015 Category: Bioinformatics Authors: Adriana Pereira de Souza, Amanda Paula Pedroso, Regina Lúcia Harumi Watanabe, Ana Paula Segantine Dornellas, Valter Tadeu Boldarine, Helen Julie Laure, Claudia Maria Oller do Nascimento, Lila Missae Oyama, José Cesar Rosa and Eliane Beraldi Ribeiro Source Type: research
Gender-specific effects of intrauterine growth restriction on the adipose tissue of adult rats: a proteomic approach
Conclusions:
The proteomic analysis of adipose tissue showed that, although IUGR affected pathways of substrate and energy metabolism in both males and females, important gender differences were evident. While IUGR males displayed alterations pointing to a predisposition to later development of obesity, the alterations observed in IUGR females pointed to a metabolic status of established obesity, in agreement with their increased fat pads mass. (Source: Proteome Science)
Source: Proteome Science - December 2, 2015 Category: Bioinformatics Authors: Adriana de SouzaAmanda PedrosoRegina WatanabeAna DornellasValter BoldarineHelen LaureClaudia do NascimentoLila OyamaJosé RosaEliane Ribeiro Source Type: research
Hepatocytes respond differently to major dietary trans fatty acid isomers, elaidic acid and trans-vaccenic acid
It has been discussed if the adverse health effect associated with the ingestion of trans fatty acids correlates with the food source, as the composition of the isomers varies in different foods. We have investig... (Source: Proteome Science)
Source: Proteome Science - December 1, 2015 Category: Bioinformatics Authors: Toke P. Krogager, Lone Vendel Nielsen, Derya Kahveci, Thomas F. Dyrlund, Carsten Scavenius, Kristian W. Sanggaard and Jan J. Enghild Source Type: research
The calcified eggshell matrix proteome of a songbird, the zebra finch (Taeniopygia guttata)
The proteins of avian eggshell organic matrices are thought to control the mineralization of the eggshell in the shell gland (uterus). Proteomic analysis of such matrices identified many candidates for such a ... (Source: Proteome Science)
Source: Proteome Science - December 1, 2015 Category: Bioinformatics Authors: Karlheinz Mann Source Type: research
The calcified eggshell matrix proteome of a songbird, the zebra finch (Taeniopygia guttata)
Conclusions:
The results indicate that ovocleidin-116, ovocleidin-17, ovocalyxin-36 and ovocalyxin-32 may be universal avian eggshell-mineralizing proteins. All the more important it is to elucidate the role of these proteins at the molecular level. This cannot be achieved by proteomic studies but will need application of other methods, such as atomic force microscopy or gene knockouts. However, it will also be important to analyze more eggshell matrices of different avian families to unequivocally identify other mineralization toolkit proteins apart from ovocleidins and ovocalyxins. Progress in this respect will depend cr...
Source: Proteome Science - December 1, 2015 Category: Bioinformatics Authors: Karlheinz Mann Source Type: research
