European Guidelines for Obesity Management in Adults with a Very Low-Calorie Ketogenic Diet: A Systematic Review and Meta-Analysis
Conclusions: The VLCKD can be recommended as an effective dietary treatment for individuals with obesity after considering potential contra-indications and keeping in mind that any dietary treatment has to be personalized.Prospero Registry: The assessment of the efficacy of VLCKD on body weight, body composition, glycemic and lipid parameters in overweight and obese subjects: a meta-analysis (CRD42020205189).Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - April 21, 2021 Category: Eating Disorders & Weight Management Source Type: research

Prevalence of Micronutrient Deficiency after Bariatric Surgery
Conclusion: As seen in other studies, the follow-up frequency decreased over the years. Despite intensive substitution, the extent of some deficiencies increased or did not improve. These results suggest reinforcing measures to motivate patients for regular follow-up visits, considering closer monitoring schedules, and improving supplementation strategies.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - April 1, 2021 Category: Eating Disorders & Weight Management Source Type: research

Obesity, Blood Pressure, and Intraocular Pressure: A Cross-Sectional Study in Italian Children
Conclusions: Our results show that high IOP affects 12.5% of 8-year-old school children and appears to be associated with high BP related to a high BMI.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - April 1, 2021 Category: Eating Disorders & Weight Management Source Type: research

Triglycerides Mediate Body Mass Index and Nonalcoholic Fatty Liver Disease: A Population-Based Study
Conclusion: A high BMI was an independent risk factor for incident NAFLD, and a high TG level was a risk factor in the high-BMI group (BMI ≥24). TG contributes about 25% to incident NAFLD in people with obesity.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - March 29, 2021 Category: Eating Disorders & Weight Management Source Type: research

The Role of Sleep Curtailment on Leptin Levels in Obesity and Diabetes Mellitus
Emerging evidence has identified sleep as a significant, but modifiable, risk factor for metabolic syndrome, diabetes, and obesity. Leptin, an adipocyte-derived peptide and a regulator of food intake and energy expenditure, has been shown to be associated with a short sleep duration in the pathophysiology of obesity and consequently type 2 diabetes. This review focuses on the current evidence indicating the effects of a short sleep duration on the regulation of leptin concentration in association with obesity and diabetes mellitus. In summary, the evidence suggests that sleep deprivation, by affecting leptin regulation, ma...
Source: Obesity Facts - March 23, 2021 Category: Eating Disorders & Weight Management Source Type: research

Patients with Severe Obesity during the COVID-19 Pandemic: How to Maintain an Adequate Multidisciplinary Nutritional Rehabilitation Program?
Background: The COVID-19 pandemic is spreading all over the world, particularly in developed countries where obesity is also widespread. There is a high frequency of increased BMI in patients admitted to intensive care for SARS-CoV-2 infection with a major severity in patients with an excess of visceral adiposity. Patients at risk of severe SARS-CoV-2 acute respiratory syndrome are characterised by the high prevalence of pre-existing diseases (high blood pressure and cardiovascular disease, diabetes, chronic respiratory disease, or cancer), most of them typically present in severely obese patients. Indeed, the biological r...
Source: Obesity Facts - March 19, 2021 Category: Eating Disorders & Weight Management Source Type: research

Effects of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy on Bone Mineral Density in Zucker Diabetic Fatty Rats: A Short-Term Comparative Study
Conclusions: Despite its excellent ability to provide short-term glycemic control, the RYGB procedure could led to more severe impairment of bone health compared to the SG procedure. Bone health should be procured after bariatric surgery, especially with the RYGB procedure. Early detection of BMD and BTM may help to avoid deterioration of bone.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - March 4, 2021 Category: Eating Disorders & Weight Management Source Type: research

The H2020 “NoHoW Project”: A Position Statement on Behavioural Approaches to Longer-Term Weight Management
There is substantial evidence documenting the effects of behavioural interventions on weight loss (WL). However, behavioural approaches to initial WL are followed by some degree of longer-term weight regain, and large trials focusing on evidence-based approaches to weight loss maintenance (WLM) have generally only demonstrated small beneficial effects. The current state-of-the-art in behavioural interventions for WL and WLM raises questions of (i) how we define the relationship between WL and WLM, (ii) how energy balance (EB) systems respond to WL and influence behaviours that primarily drive weight regain, (iii) how inter...
Source: Obesity Facts - March 4, 2021 Category: Eating Disorders & Weight Management Source Type: research

Efficiency of a 15-Week Weight-Loss Program, Including a Low-Calorie Formula Diet, on Glycemic Control in Patients with Type 2 Diabetes Mellitus and Overweight or Obesity
Conclusions: A structured weight-loss program is effective in the short term in reducing HbA1c, weight, and antidiabetic medication in patients with T2DM who are overweight or obese. Levels of HDL-C and LDL-C were not affected by short-term weight loss. The decline in mental health and the long-term effects of improved glycemic control require further trials.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - February 18, 2021 Category: Eating Disorders & Weight Management Source Type: research

Visual Analysis of Biomarkers Reveals Differences in Lipid Profiles and Liver Enzymes before and after Gastric Sleeve and Bypass
Conclusions: Beanplots allow intuitive visualization of population distributions. Analysis of this large population-based data set using beanplots suggests comparable efficacies of both types of surgery in reducing diabetes. RYGB surgery reduced dyslipidemia more effectively than SG. The trend toward a larger decrease in liver enzyme activities following SG is a subject for further investigation.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - February 5, 2021 Category: Eating Disorders & Weight Management Source Type: research

MicroRNA Expression Profiles in the Subcutaneous Adipose Tissues of Morbidly Obese Chinese Women
Conclusions: MiRNA downregulation is a hallmark of intact SAT in a morbidly obese state. Transcription (DNA-dependent), small-molecule metabolic processes, the MAPK signaling pathway, and cancer-related pathways may play important roles in the occurrence and development of obesity. For the first time, we proved thatHMGA2, a target gene of let-7a-5p, is upregulated in the SAT of morbidly obese Chinese women.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - February 5, 2021 Category: Eating Disorders & Weight Management Source Type: research

Suggested Gestational Weight Gain for Chinese Women and Comparison with Institute of Medicine Criteria: A Large Population-Based Study
Conclusion: This study suggests a modest GWG goal compared to IOM recommendations based on a large Chinese cohort.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - February 3, 2021 Category: Eating Disorders & Weight Management Source Type: research

Promoter Methylation of < b > < i > LEP < /i > < /b > and < b > < i > LEPR < /i > < /b > before and after Bariatric Surgery: A Cross-Sectional Study
Discussion: These findings strengthen the suggestion that there is an association between LEP expression andLEP methylation in obesity. We suggest that the epigenetic profile ofLEP might be influenced by leptin serum levels in the form of a regulating feedback mechanism.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - February 2, 2021 Category: Eating Disorders & Weight Management Source Type: research

Metabolic Syndrome in Offspring of Parents with Metabolic Syndrome: A Meta-Analysis
Conclusion: This meta-analysis showed that there is a higher risk of MetS in the offspring of parents with MetS. However, there was no differential association of MetS according to gender and/or age of the offspring.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - January 28, 2021 Category: Eating Disorders & Weight Management Source Type: research

Association of Physical Activity and Sitting Time with Overweight/Obesity in Chinese Occupational Populations
Conclusion: Occupation activity intensity, LTPA, transportation mode, and work sitting time were associated with overweight/obesity. Reducing work sitting time, moderate and heavy occupation activity intensity, and an active transportation mode could help male employees decrease the risk of overweight/obesity. Increasing leisure-time physical activity could reduce the risk of overweight/obesity in women. Our findings provided insight into the association of physical activity and sitting time with overweight/obesity. It will be necessary to carry out workplace-based interventions, have an active transportation mode, and inc...
Source: Obesity Facts - January 26, 2021 Category: Eating Disorders & Weight Management Source Type: research