Long-term trends in obesity prevalence by socio-economic group in five European countries and the USA: The relevance of the diffusion of innovations theory
Discussion: Recent trends in obesity prevalence by SEG are mostly in line with the diffusion of innovations theory, however, no diffusion from higher to lower SEGs at the start of the epidemic was found. The stagnation among higher SEGs but not lower SEGs suggests that the latter will likely experience the greatest future burden. (Source: Obesity Facts)
Source: Obesity Facts - September 15, 2022 Category: Eating Disorders & Weight Management Source Type: research

Weight Loss, Type 2 Diabetes, and Nutrition in 355 Patients with Obesity Undergoing Sleeve Gastrectomy with Transit Bipartition: Two-Year Outcomes
This study examined whether 355 obese patients with type 2 diabetes (T2D) of varying duration and severity experienced equivalent weight loss and T2D remission following a newer sleeve gastrectomy (SG) procedure—SG with transit bipartition (SG-TB). Methods: Primary outcomes were changes in body mass index (BMI), total weight loss (TWL), excess BMI loss (EBMIL), A1C, and diabetes medication use through 24 months. Results: Between December 2015 and December 2019, 399 patients who underwent SG-TB reached the 2-year time point. Follow-up was possible in 355 patients (89.0%): 206 females (58.0%), mean age 51.5 years (24.0...
Source: Obesity Facts - September 7, 2022 Category: Eating Disorders & Weight Management Source Type: research

Does Neutrophil-Lymphocyte Ratio Correlate with the Improvement of Hepatosteatosis after Laparoscopic Sleeve Gastrectomy?
Conclusion: However, we found laparoscopic sleeve gastrectomy is associated with significant improvement in hepatosteatosis and inflammatory parameters; no correlation between the improvement in hepatosteatosis and NLR was seen at 1 year.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - August 30, 2022 Category: Eating Disorders & Weight Management Source Type: research

Does Neutrophil-lymphocyte ratio correlate with the improvement of hepatosteatosis after laparoscopic sleeve gastrectomy?
Conclusion: However we found laparoscopic sleeve gastrectomy is associated with significant improvement in hepatosteatosis and inflammatory parameters, no correlation between the improvement in hepatosteatosis and NLR was seen at one-year. (Source: Obesity Facts)
Source: Obesity Facts - August 30, 2022 Category: Eating Disorders & Weight Management Source Type: research

Suggestive Evidence for an Antidepressant Effect of Metreleptin Treatment in Patients with Lipodystrophy
Conclusion: Our study for the first time revealed suggestive evidence for an antidepressant effect of metreleptin in patients with LD. Metreleptin caused a rapid drop in depression scores within 1 week of treatment. A reduction of the depression score was also observed in 2 of the 3 LD patients whose BDI scores were in the normal range before start of the treatment. The reduction in total scores of BDI was still apparent after 3 months (T4) of dosing. This observation matches findings obtained in clinical case studies of AN patients, in whom depression scores also dropped during the first week of metreleptin treatment. It ...
Source: Obesity Facts - August 29, 2022 Category: Eating Disorders & Weight Management Source Type: research

Suggestive evidence for an antidepressant effect of metreleptin treatment in patients with lipodystrophy
Conclusion: Our study for the first time revealed suggestive evidence for an antidepressant effect of metreleptin in patients with LD. Metreleptin caused a rapid drop in depression scor es within one week of treatment. A reduction of the depression score was also observed in two of the three LD patients whose BDI scores were in the normal range before start of the treatment. The reduction in total scores of BDI were still apparent after three months (T4) of dosing. This observation matches findings obtained in clinical case studies of AN patients, in whom depression scores also dropped during the first week of metreleptin ...
Source: Obesity Facts - August 29, 2022 Category: Eating Disorders & Weight Management Source Type: research

Weight Change over 4 Years and Risk of Cardiovascular Diseases in China: The China Health and Retirement Longitudinal Study
Conclusion: Weight changes (weight gain or loss more than 5 kg) during middle age were associated with an increased risk of CVD in middle-aged and elderly Chinese individuals.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - August 25, 2022 Category: Eating Disorders & Weight Management Source Type: research

Weight Change over 4 Years and Risk of Cardiovascular Diseases in China: The China Health and Retirement Longitudinal Study
Conclusion: Weight changes (weight gain or loss more than 5 kg) during middle age were associated with an increased risk of CVD in middle-aged and elderly Chinese individuals. (Source: Obesity Facts)
Source: Obesity Facts - August 25, 2022 Category: Eating Disorders & Weight Management Source Type: research

Weight change over 4 years and risk of cardiovascular diseases in Chinese: The China Health and Retirement Longitudinal Study
Abstract Introduction: Previous studies had reported the impact of weight changes in middle age on the incidence of cardiovascular disease (CVD), but the results were inconsistent. In present study, we aimed to investigated the impact of a 4-year weight change on the risk of CVD in middle-aged and elderly Chinese individuals. Methods: Using nationally representative data from the China Health and Retirement Longitudinal Study, 7,530 participants (age: 58.2 ± 8.9 years) were included. Weight change was calculated by subtracting weight at baseline from that at 4-year follow-up. Weight change over 4 years was divided into ...
Source: Obesity Facts - August 25, 2022 Category: Eating Disorders & Weight Management Source Type: research

Abdominal Morphologic Changes in MRI during Gastric Balloon Therapy
Conclusion: The gastric balloon is a temporary and successful option for weight reduction by reducing body fat, liver volume but also muscle mass. (Source: Obesity Facts)
Source: Obesity Facts - August 16, 2022 Category: Eating Disorders & Weight Management Source Type: research

First account of psychological changes perceived by a female with congenital leptin deficiency upon treatment with metreleptin
Two psychiatric interviews of a 39-year old female with congenital leptin deficiency were conducted to define psychological changes fourteen and 165 days after initiation of treatment with human recombinant leptin (metreleptin). The most pronounced initial experience related to the reduced preoccupation with food. An improved mood was reported by the patient, which she associated with this reduced preoccupation. Her mood remained elevated upon recontact, whereas she was no longer preoccupied with food. Overall, the interviews provides a vivid account of the subjective experiences upon initiation of treatment. Some of the f...
Source: Obesity Facts - August 11, 2022 Category: Eating Disorders & Weight Management Source Type: research

Risk factors influencing seroconversion after inactive SARS-CoV-2 vaccination in people living with obesity
Abstract Introduction To investigate the antibody titers against SARS-CoV-2 spike antigens, and the risk factors affecting antibody levels in people living with obesity (PwO) after inactive SARS-CoV-2 vaccine (Corona Vac) administration. Methods 169 consecutive patients with obesity who visited the Center for Obesity Management at Istanbul University-Cerrahpa şa, Cerrahpaşa Medical Faculty Hospitals, between May and August 2021, were invited to the study. The non-obese control group was recruited from 191 subjects who visited the Cerrahpaşa Hospitals Vaccination Unit. The study group and the non-obese control group ...
Source: Obesity Facts - August 3, 2022 Category: Eating Disorders & Weight Management Source Type: research