Use of Liraglutide 3.0 mg for Weight Management in a Real-World Setting in Switzerland
Conclusion: In a real-world setting with low insurance coverage and with most patients not reaching the recommended maintenance dose of 3.0 mg, the use of liraglutide, in combination with diet and exercise, was associated with clinically meaningful weight loss.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - August 20, 2021 Category: Eating Disorders & Weight Management Source Type: research

Development and Validation of a Novel Scoring System for Noninvasive Nonalcoholic Steatohepatitis Detection in Bariatric Patients
Conclusion: The NI-NASH-DS is easy-to-use, inexpensive, and noninvasive and can reliably detect NASH in patients with morbid obesity. Due to its simplicity, it can be used frequently and repeatedly.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - August 20, 2021 Category: Eating Disorders & Weight Management Source Type: research

Interactions between Prepregnancy Overweight and Passive Smoking for Macrosomia and Large for Gestational Age in Chinese Pregnant Women
Conclusions: Prepregnancy overweight/obesity was associated with an increased risk of macrosomia in Chinese women synergistically with passive smoking during pregnancy, and most of the association was not modified by hyperglycemia during pregnancy.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - August 20, 2021 Category: Eating Disorders & Weight Management Source Type: research

Serum 25OHD < sub > 3 < /sub > of Obese Mice Is Affected by Liver Injury and Correlates with Testosterone Levels and Sperm Motility
Conclusion: Our research shows that there is a metabolic interference mediated by 25OHD3 and testosterone between obesity and low sperm motility. The results of this study can provide a scientific basis for studying the mechanism of 25OHD3 and hormone regulation and treating obese people with low sperm motility.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - August 20, 2021 Category: Eating Disorders & Weight Management Source Type: research

Relation of Maximum Lifetime Body Mass Index with Age at Hemodialysis Initiation and Vascular Complications in Japan
Conclusion: A high max BMI contributed to early hemodialysis initiation independent of diabetes. Furthermore, PDR was associated with a high max BMI and early hemodialysis initiation. These results suggest that weight reduction in young chronic kidney disease patients with obesity may prevent hemodialysis and blindness.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - August 13, 2021 Category: Eating Disorders & Weight Management Source Type: research

Experience of Excess Skin and Attitude to Body Contouring Surgery of a Chinese Post-Bariatric Population
Conclusions: Most Chinese post-bariatric patients have excess skin and are bothered by impaired HRQoL. The abdomen and upper arms are the sites where patients are most seriously affected and most eager for BCS. The conservative attitude toward BCS and the cost without reimbursement are the main barriers.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - August 6, 2021 Category: Eating Disorders & Weight Management Source Type: research

The Role of Obesity in Predicting the Clinical Outcomes of COVID-19
Conclusion: COVID-19 patients with overweight and obesity presented with more severe clinical findings. Health-care providers should take into account that people living with overweight and obesity are at higher risk for COVID-19 and its complications.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - August 5, 2021 Category: Eating Disorders & Weight Management Source Type: research

Metabolic Response to Submaximal and Maximal Exercise in People with Severe Obesity, Prediabetes, and Diabetes
Conclusions: PwO demonstrate restricted metabolic response during maximal exercise. Particularly, those with prediabetes already show metabolic inflexibility during exercise, similarly to those with type 2 diabetes. These findings also suggest a potential role of cardiopulmonary exercise testing in detecting early metabolic alterations in PwO.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - July 30, 2021 Category: Eating Disorders & Weight Management Source Type: research

Bariatric Surgery Outcomes in Patients with Latent Autoimmune Diabetes of the Adult
This study shows that patients with LADA depict remarkable reduction of body weight and insulin requirements over long-term after bariatric surgery. So, LADA should not be considered a contraindication for bariatric surgery yet should only be recommended for patients with concomitant obesity with the primary aim of achieving sustained weight loss.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - July 28, 2021 Category: Eating Disorders & Weight Management Source Type: research

Lifestyle Intervention for Overweight/Obese Pregnant Women with Polycystic Ovarian Syndrome: Lessons and Challenges
Conclusions: Our study showed that lifestyle intervention of diet and exercise did not affect GWG, glucolipid metabolism, and perinatal outcomes of overweight/obese pregnant women with PCOS. However, women with good compliance can benefit from the lifestyle intervention for GWG. We believe that future studies should focus on trial design and increasing compliance to improve the quality of the study.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - July 26, 2021 Category: Eating Disorders & Weight Management Source Type: research

Bariatric Surgery-Associated Myelopathy
Bariatric surgery is gaining acceptance as an efficient treatment modality for adults and adolescents with morbid obesity. The early postbariatric period has the potential to induce an immunomodulatory imbalance due to the development or worsening of nutritional deficiencies, changes in hormonal balance (specifically after sleeve gastrectomy), and a shift in the proinflammatory cytokine profile along with a major change in the gut microbiome and permeability. These changes may induce encephalomyelitic T cell activity, change neural barrier permeability, and induce gut dysbioisis, favoring a proinflammatory metabolic profil...
Source: Obesity Facts - July 26, 2021 Category: Eating Disorders & Weight Management Source Type: research

Development of a BMI-Assigned Stunkard Scale for the Evaluation of Body Image Perception Based on Data of the SOS Reference Study
Conclusion: Stunkard ’s figure rating scale can be used with confidence to assess weight status. Silhouette selection accurately classifies subjects as overweight or obese.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - July 20, 2021 Category: Eating Disorders & Weight Management Source Type: research

Carbohydrates to Prevent and Treat Obesity in a Murine Model of Diet-Induced Obesity
Discussion: A diet high in sucrose or starch induces less obesity and obesity-associated complications. Moreover, switching obese mice to a sucrose-rich diet elicits weight loss and decreases obesity-induced metabolic complications, highlighting the potential of carbohydrates to treat obesity.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - July 20, 2021 Category: Eating Disorders & Weight Management Source Type: research

Tamarind Multifunctional Protein: Safety and Anti-Inflammatory Potential in Intestinal Mucosa and Adipose Tissue in a Preclinical Model of Diet-Induced Obesity
Conclusion: Based on histological and stereological analysis, the use of TTIp is potentially safe and anti-inflammatory in the evaluated obesity model and can be investigated as a possible adjuvant in obesity therapy.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - July 13, 2021 Category: Eating Disorders & Weight Management Source Type: research

Relevance of Physical Activities, Sedentary Behaviors, and Genetic Predisposition in Body Fatness: Population-Based Study on Chinese Adults
Conclusion: MVPA may be a protective factor against obesity, and prolonged television watching may accentuate adiposity. These putative effects may be more pronounced among individuals with a high genetic risk of a high BMI.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - July 9, 2021 Category: Eating Disorders & Weight Management Source Type: research