Effect of Hedan tablets on body weight and insulin resistance in patients with metabolic syndrome
Conclusion: The Hedan tablets significantly improve BW, BMI, TG/HDLc, and adiponectin in patients with MetS. Thus, Hedan tablets may be used as an adjunct to existing MetS management methods. (Source: Obesity Facts)
Source: Obesity Facts - December 30, 2021 Category: Eating Disorders & Weight Management Source Type: research

Prevalence of Thinness, Overweight, Obesity, and Central Obesity in Finnish School-Aged Children: A Comparison of National and International Reference Values
Conclusion: Our findings show that WHO overestimates the prevalence of overweight and obesity, while IOTF overrates thinness. Thus, comparing prevalence rates between studies requires caution. The novelty of this study is the comparison of the cutoff values for overweight with central obesity. The choice of reference system affects the generalizability of the research results. (Source: Obesity Facts)
Source: Obesity Facts - December 22, 2021 Category: Eating Disorders & Weight Management Source Type: research

Prevalence of thinness, overweight, obesity and central obesity in Finnish school-aged children: a comparison of national and international reference values
Conclusion: Our findings show that WHO overestimates the prevalence of overweight and obesity, while IOTF overrates thinness. Thus, comparing prevalence r ates between studies requires caution. The novelty of this study is the comparison of the cut-off values for overweight with central obesity. The choice of reference system affects the generalizability of the research results. (Source: Obesity Facts)
Source: Obesity Facts - December 22, 2021 Category: Eating Disorders & Weight Management Source Type: research

Effect of a 1-year controlled lifestyle intervention on body weight and other risk markers (the Healthy Lifestyle Community Programme, cohort 2)
Conclusion: The intervention successfully reduced body weight, BMI, waist circumference, REM-C, and RHR. However, at 1 year, effectiveness of the intervention regarding other risk markers was either very modest or could not be shown. (Source: Obesity Facts)
Source: Obesity Facts - December 17, 2021 Category: Eating Disorders & Weight Management Source Type: research

Association between marginally low birth weight and obesity-related outcomes indirect effects via ADHD and abnormal eating
Conclusion: Our study suggests the hypothetical role of ADHD and abnormal eating as underlying mechanisms in the association between MBLW and obesity-related outcomes, which provides novel scientific evidence for interventions of childhood development. (Source: Obesity Facts)
Source: Obesity Facts - December 16, 2021 Category: Eating Disorders & Weight Management Source Type: research

Weight Changes in Type 2 Diabetes and Cancer Risk: A Latent Class Trajectory Model Study
Conclusion: Patients who lost weight after T2D diagnosis had higher risks for ORC (in men) and higher all-cause mortality (both genders) than patients with stable obesity.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - December 13, 2021 Category: Eating Disorders & Weight Management Source Type: research

Effects of Weight Loss on Adipose and Muscular Neuropilin 1 mRNA Expression in Obesity: Potential Implication in SARS-CoV-2 Infections?
Conclusion: NRP-1AT is related to adipose insulin sensitivity in obesity. Weight loss-induced decline of NRP-1AT seems not to be involved in metabolic short- and long-term improvements after weight loss. However, weight loss-induced reduction of both NRP-1AT and ACE-2AT indicates a lower susceptibility of adipose tissue for SARS-CoV-2 after body weight reduction.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - December 10, 2021 Category: Eating Disorders & Weight Management Source Type: research

Bariatric Surgery as the One Route to Achieving Donor Heart Transplantation in a Patient with a Left-Ventricular Assist Device
Bariatric and metabolic surgery is currently the most effective procedure of achieving and maintaining weight loss. In the case under discussion, a 48-year-old male patient with heart insufficiency and an implanted left-ventricular assist device (LVAD) wanted to reduce his high BMI (48.6 kg/m2), so as to qualify for the heart transplant waiting list. According to the guidelines, he underwent all the required preoperative testing, which included psychosomatic clarifications, determination of endocrinological causes, and a nutritional consultation. During laparoscopic sleeve gastrectomy, a cardiac technician was present to s...
Source: Obesity Facts - December 10, 2021 Category: Eating Disorders & Weight Management Source Type: research

Acknowledgement to Reviewers
Obes Facts 2021;14:675 –676 (Source: Obesity Facts)
Source: Obesity Facts - December 7, 2021 Category: Eating Disorders & Weight Management Source Type: research

NPPA promoter hypomethylation predicts central obesity development: a prospective longitudinal study in Chinese adults
The objective of this study was to examine the association between its coding gene (NPPA) methylation and obesity. Methods: Peripheral blood DNA methylation of NPPA promoter was quantified at baseline by targeted bisulfite sequencing for 2,497 community members (mean aged 53 years, 38% men) in the Gusu cohort. Obesity was repeatedly assessed by body mass index (BMI) and waist circumference (WC) at baseline and follow-up examinations. The cross-sectional, longitudinal, and prospective associations between NPPA promoter methylation and obesity were examined. Results: Of the 9 CpG loci assayed, DNA methylation levels at 6 C...
Source: Obesity Facts - December 7, 2021 Category: Eating Disorders & Weight Management Source Type: research

Maternal Serum and Cord Blood Leptin Concentrations at Delivery in Normal Pregnancies and in Pregnancies Complicated by Intrauterine Growth Restriction
Conclusions: Elevated maternal blood leptin concentrations in pregnancies complicated by IUGR may indicate a significant adverse effect of elevated leptin on fetal growth. The differences in leptin concentrations, measured in maternal serum and in cord blood, between the study subjects and controls suggest that deregulated leptin levels may increase the risk of obstetric complications associated with placental insufficiency.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - December 6, 2021 Category: Eating Disorders & Weight Management Source Type: research

Bone Response to High-Intensity Interval Training versus Moderate-Intensity Continuous Training in Adolescents with Obesity
Conclusions: In addition to inducing greater BMI and FM percentage decreases in comparison to MICT, HIIT improves multisite bone density, geometry, and strength, which heighten the justification for HIIT as part of weight loss interventions in adolescents with obesity.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - December 3, 2021 Category: Eating Disorders & Weight Management Source Type: research

The effect of body weight and alcohol consumption on hyperuricemia and their attributable population fractions: A National health survey in China
Conclusion: There are significant sex and geographic difference on population attributable risk of hyperu ricemia due to modifiable risk factors. More tailored prevention strategies are needed to prevent hyperuricemia through weight loss and the reduction of alcohol consumption. (Source: Obesity Facts)
Source: Obesity Facts - November 26, 2021 Category: Eating Disorders & Weight Management Source Type: research

Erratum
Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - November 25, 2021 Category: Eating Disorders & Weight Management Source Type: research

Psychological Aspects of Treatment with Intragastric Balloon for Management of Obesity: A Systematic Review of the Literature
Conclusion: In line with the available literature on obesity and bariatric surgery interventions, poor mental health appears to be an important barrier for successful weight loss among patients with obesity undergoing IGB treatment. In order to improve the efficacy and effectiveness of the IGB therapy, more comprehensive and standardized studies are needed to provide insight into the psychological mechanisms maintaining weight management issues.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - November 23, 2021 Category: Eating Disorders & Weight Management Source Type: research