MicroRNA Expression Profiles in the Subcutaneous Adipose Tissues of Morbidly Obese Chinese Women

Conclusions: MiRNA downregulation is a hallmark of intact SAT in a morbidly obese state. Transcription (DNA-dependent), small-molecule metabolic processes, the MAPK signaling pathway, and cancer-related pathways may play important roles in the occurrence and development of obesity. For the first time, we proved thatHMGA2, a target gene of let-7a-5p, is upregulated in the SAT of morbidly obese Chinese women.Obes Facts
Source: Obesity Facts - Category: Eating Disorders & Weight Management Source Type: research