Overcoming challenges as a female cardiologist in the Middle East
Nature Reviews Cardiology, Published online: 16 September 2022; doi:10.1038/s41569-022-00775-wWhen I have encountered obstacles in the three decades of my career, I have found that self-confidence and courage are the most effective traits for achieving my goals as a female cardiologist. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - September 16, 2022 Category: Cardiology Authors: Nizal Sarrafzadegan Source Type: research
Vitamin K antagonists for RHD-associated AF
Nature Reviews Cardiology, Published online: 16 September 2022; doi:10.1038/s41569-022-00777-8Vitamin K antagonists for RHD-associated AF (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - September 16, 2022 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research
Functional testing after PCI in high-risk patients
Nature Reviews Cardiology, Published online: 16 September 2022; doi:10.1038/s41569-022-00779-6Functional testing after PCI in high-risk patients (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - September 16, 2022 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research
No benefit of PCI in ischaemic LV dysfunction
Nature Reviews Cardiology, Published online: 16 September 2022; doi:10.1038/s41569-022-00778-7No benefit of PCI in ischaemic LV dysfunction (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - September 16, 2022 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research
Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology
Nature Reviews Cardiology, Published online: 15 September 2022; doi:10.1038/s41569-022-00759-wIn this Review, Nattel and colleagues discuss the evidence suggesting a pathophysiological role of cardiomyocyte inflammatory signalling in atrial fibrillation, consider the therapeutic potential associated with these signalling pathways, including strategies promoting the resolution of inflammation, and highlight crucial questions to be addressed in future research. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - September 15, 2022 Category: Cardiology Authors: Dobromir Dobrev Jordi Heijman Roddy Hiram Na Li Stanley Nattel Source Type: research
CVD screening trial in older men misses primary end point but suggests benefits
Nature Reviews Cardiology, Published online: 15 September 2022; doi:10.1038/s41569-022-00781-yAn invitation to undergo comprehensive cardiovascular screening in men aged 65–74 years did not lower the incidence of death from any cause after 5 years in the DANCAVAS trial, but data suggest benefits in some outcomes and in reducing mortality in men aged (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - September 15, 2022 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research
Extravascular ICDs are safe and effective
Nature Reviews Cardiology, Published online: 15 September 2022; doi:10.1038/s41569-022-00780-zExtravascular implantable cardioverter–defibrillators are safe and effective at detecting and terminating ventricular arrhythmias induced at the time of implantation. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - September 15, 2022 Category: Cardiology Authors: Gregory B. Lim Source Type: research
Branched-chain amino acids in cardiovascular disease
Nature Reviews Cardiology, Published online: 05 September 2022; doi:10.1038/s41569-022-00760-3In this Review, McGarrah and White outline the major factors regulating branched-chain amino acid (BCAA) abundance and metabolic fate, highlight molecular mechanisms connecting impaired BCAA homeostasis to cardiovascular disease and discuss the epidemiological evidence connecting BCAAs with various cardiovascular disease states. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - September 5, 2022 Category: Cardiology Authors: Robert W. McGarrah Phillip J. White Source Type: research
Cyclic nucleotide phosphodiesterases as therapeutic targets in cardiac hypertrophy and heart failure
Nature Reviews Cardiology, Published online: 01 September 2022; doi:10.1038/s41569-022-00756-zIn this Review, Fischmeister and colleagues describe cAMP and cGMP signalling in cardiomyocytes and summarize the various phosphodiesterase (PDE) families expressed in the heart and how they are modified in heart failure. They also assess the potential use of inhibitors or activators of specific PDEs to treat heart failure. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - September 1, 2022 Category: Cardiology Authors: Rima Kamel J érôme Leroy Gr égoire Vandecasteele Rodolphe Fischmeister Source Type: research
Changing epidemiology of congenital heart disease: effect on outcomes and quality of care in adults
Nature Reviews Cardiology, Published online: 31 August 2022; doi:10.1038/s41569-022-00749-yThe mortality and birth prevalence of congenital heart disease (CHD) have shifted in the past 50 years owing to advances in diagnosis and treatment. In this Review, Marelli and colleagues discuss the effect of this shift in CHD epidemiology on outcomes and disease burden in adult patients and describe new initiatives and technology that can improve the delivery of health care. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - August 31, 2022 Category: Cardiology Authors: Aihua Liu Gerhard-Paul Diller Philip Moons Curt J. Daniels Kathy J. Jenkins Ariane Marelli Source Type: research
ASGR1 inhibition stimulates cholesterol excretion
Nature Reviews Cardiology, Published online: 17 August 2022; doi:10.1038/s41569-022-00768-9Inhibition of asialoglycoprotein receptor 1 (ASGR1) reduces cholesterol levels by promoting cholesterol excretion to bile and faeces. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - August 17, 2022 Category: Cardiology Authors: Karina Huynh Source Type: research
LIPC variant in combined hypocholesterolaemia
Nature Reviews Cardiology, Published online: 17 August 2022; doi:10.1038/s41569-022-00765-yLIPC variant in combined hypocholesterolaemia (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - August 17, 2022 Category: Cardiology Authors: Gregory B. Lim Source Type: research
Ethnic disparities in age of onset of hypertension
Nature Reviews Cardiology, Published online: 17 August 2022; doi:10.1038/s41569-022-00767-wEthnic disparities in age of onset of hypertension (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - August 17, 2022 Category: Cardiology Authors: Gregory B. Lim Source Type: research
Gout flares can precede cardiovascular events
Nature Reviews Cardiology, Published online: 17 August 2022; doi:10.1038/s41569-022-00766-xGout flares can precede cardiovascular events (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - August 17, 2022 Category: Cardiology Authors: Gregory B. Lim Source Type: research
Donor macrophages influence rejection of transplanted hearts
Nature Reviews Cardiology, Published online: 16 August 2022; doi:10.1038/s41569-022-00764-zIn mouse transplanted hearts, donor CCR2+ macrophages promote allograft rejection, whereas donor CCR2− macrophages promote allograft survival. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - August 16, 2022 Category: Cardiology Authors: Gregory B. Lim Source Type: research
