Mini Reviews in Medicinal Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Alzheimer's Disease and Cancer: Common Targets
Mini Rev Med Chem. 2023 Nov 21. doi: 10.2174/0113895575263108231031132404. Online ahead of print.ABSTRACTThere is growing epidemiologic evidence of an inverse association between cancer and AD. In addition, both cell survival and death are regulated by the same signaling pathways, and their abnormal regulation may be implicated in the occurrence and development of cancer and AD. Research shows that there may be a common molecular mechanism between cancer and AD. This review will discuss the role of GSK3, DAPK1, PP2A, P53 and CB2R in the pathogenesis of cancer and AD and describe the current research status of drug developm...
Source: Mini Reviews in Medicinal Chemistry - December 1, 2023 Category: Chemistry Authors: Xueqing Yang Jinlian Dai Chenglong Wu Zongliang Liu Source Type: research

A Literature Review Focusing on the Antiviral Activity of [1,2,4] and [1,2,3]-triazoles
Mini Rev Med Chem. 2023 Nov 24. doi: 10.2174/0113895575277122231108095511. Online ahead of print.ABSTRACTOut of a variety of heterocycles, triazole scaffolds have been shown to play a significant part in a wide array of biological functions. Many drug compounds containing a triazole moiety with important antimicrobial, anticancer and antidepressant properties have been commercialized. In addition, the triazole scaffold exhibits remarkable antiviral activity either incorporated into nucleoside analogs or non-nucleosides. Many synthetic techniques have been produced by scientists around the world as a result of their wide-ra...
Source: Mini Reviews in Medicinal Chemistry - November 27, 2023 Category: Chemistry Authors: Thoraya A Farghaly Ghada S Masaret Sayed M Riyadh Marwa F Harras Source Type: research

In Silico Pharmacokinetics, Molecular Docking and Molecular Dynamics Simulation Studies of Nucleoside Analogs for Drug Discovery- A Mini Review
This article portrays the current status of these methods and highlights some remarkable contributions to the development of nucleoside analogs with optimized bioactivity.PMID:37957918 | DOI:10.2174/0113895575258033231024073521 (Source: Mini Reviews in Medicinal Chemistry)
Source: Mini Reviews in Medicinal Chemistry - November 14, 2023 Category: Chemistry Authors: Sarkar M A Kawsar Nasrin S Munia Supriyo Saha Yasuhiro Ozeki Source Type: research