Mini Reviews in Medicinal Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Diabetes Pharmacotherapy and its effects on the Skeletal Muscle Energy Metabolism
Mini Rev Med Chem. 2024 Feb 16. doi: 10.2174/0113895575299439240216081711. Online ahead of print.ABSTRACTThe disorders of skeletal muscle metabolism in patients with Type 2 diabetes mellitus (T2DM), such as mitochondrial defection and glucose transporters (GLUTs) translocation dysfunctions, are not uncommon. Therefore, when anti-diabetic drugs were used in various chronic diseases associated with hyperglycemia, the impact on skeletal muscle should not be ignored. However, current studies mainly focus on muscle mass rather than metabolism or functions. Anti-diabetic drugs might have a harmful or beneficial impact on skeleta...
Source: Mini Reviews in Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Baowen Yu Dong Wang Junming Zhou Rong Huang Tingting Cai Yonghui Hu Yunting Zhou Jianhua Ma Source Type: research

Use of Chitosan as a Precursor for Multiple Applications in Medicinal Chemistry: Recent Significant Contributions
This article reviews the main contributions published in the last ten years regarding the use and application of CS in medical chemistry. The applications exposed here involve regenerative medicine in the design of bioprocesses and tissue engineering, Pharmaceutical sciences to obtain biomaterials, polymers, biomedicine, and the use of nanomaterials and nanotechnology, toxicology, and Clinical Pharmaceuticals, emphasizing the perspectives and the direction that can take research in this area.PMID:38500287 | DOI:10.2174/0113895575275799240306105615 (Source: Mini Reviews in Medicinal Chemistry)
Source: Mini Reviews in Medicinal Chemistry - March 19, 2024 Category: Chemistry Authors: Diego Quiroga Carlos Coy-Barrera Source Type: research

Tanshinone IIA Against Cerebral Ischemic Stroke and Ischemia-Reperfusion Injury: A Review of the Current Documents
Mini Rev Med Chem. 2024 Mar 13. doi: 10.2174/0113895575299721240227070032. Online ahead of print.ABSTRACTStroke is a well-known neurological disorder that carries significant morbidity and mortality rates worldwide. Cerebral Ischemic Stroke (CIS), the most common subtype of stroke, occurs when thrombosis or emboli form elsewhere in the body and travel to the brain, leading to reduced blood perfusion. Cerebral Ischemia/Reperfusion Injury (CIRI) is a common complication of CIS and arises when blood flow is rapidly restored to the brain tissue after a period of ischemia. The therapeutic approaches currently recognized for CIS...
Source: Mini Reviews in Medicinal Chemistry - March 14, 2024 Category: Chemistry Authors: Reza Arefnezhad Alireza Nejabat Fatemeh Behjati Mona Torkamanche Hooman Zarei Motahhareh Yekkehbash Fatemeh Afsharmanesh Zahra Niknam Tannaz Jamialahmadi Amirhossein Sahebkar Source Type: research