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Therapeutic approaches for the treatment of Interstitial Lung Disease: An exploratory review on molecular mechanisms
CONCLUSION: The review highlights the rationale for conventional and novel therapeutic approaches for better management of ILD.PMID:37587813 | DOI:10.2174/1389557523666230816090112 (Source: Mini Reviews in Medicinal Chemistry)
Source: Mini Reviews in Medicinal Chemistry - August 17, 2023 Category: Chemistry Authors: Revati Amin Ruchi Pandey K Vaishali Vishak Acharya Mukesh Kumar Sinha Nitesh Kumar Source Type: research

MiRNAs: Emerging agents for therapeutic effects of polyphenols on ovarian cancer
Mini Rev Med Chem. 2023 Aug 16. doi: 10.2174/1389557523666230816090138. Online ahead of print.ABSTRACTIn terms of female reproductive tract cancers, ovarian cancer remains the principal reason for mortality globally and is notably difficult to identify in its early stages. This fact highlights the critical need to establish prevention strategies for patients with ovarian cancer, look for new robust diagnostic and prognostic markers, and identify potential targets of response to treatment. MicroRNAs (miRNAs) are one of the novel treatment targets in cancer treatment. Thus, understanding the part of miRNAs in the pathogenesi...
Source: Mini Reviews in Medicinal Chemistry - August 17, 2023 Category: Chemistry Authors: Bita Badehnoosh Nesa Rajabpoor Nikoo Reza Asemi Rana Shafabakhsh Zatollah Asemi Source Type: research

Mechanism of Action of Collagen and Epidermal Growth Factor: A Review on Theory and Research Methods
Mini Rev Med Chem. 2023 Aug 16. doi: 10.2174/1389557523666230816090054. Online ahead of print.ABSTRACTThe most abundant protein found in mammals is collagen, and there are around 28 different types of collagen found in the human body, but there are five types, namely, Type I, Type II, Type III, Type V, and Type X, most generally applied in supplements, and the five common types of collagen are available in various forms and form different sources, which result in various potential benefits. The epidermal growth factor is one of the main growth factor proteins in the skin, which has an important function in the production o...
Source: Mini Reviews in Medicinal Chemistry - August 17, 2023 Category: Chemistry Authors: Mohamad Hesam Shahrajabian Wenli Sun Source Type: research

Recent literature on the synthesis of thiazole derivatives and their biological activities
The objective of this review is to present recent advancements in the discovery of biologically active thiazole derivatives, including their synthetic methods and biological effects. This review comprehensively discusses the synthesis methods of thiazole and its corresponding biological activities within a specific timeframe, from 2017 until the conclusion of 2022.PMID:37496137 | DOI:10.2174/1389557523666230726142459 (Source: Mini Reviews in Medicinal Chemistry)
Source: Mini Reviews in Medicinal Chemistry - July 27, 2023 Category: Chemistry Authors: Thoraya A Farghaly Ghaidaa H Alfaifi Sobhi M Gomha Source Type: research

Recent Advancement in Bioactive Chalcone Hybrids as Potential Antimicrobial Agents in Medicinal Chemistry
Mini Rev Med Chem. 2023 Jul 27. doi: 10.2174/1389557523666230727102606. Online ahead of print.ABSTRACTChalcones are flavonoid-related aromatic ketones and enones generated from plants. The chalcones have a wide range of biological activities, such as anti-tumor, calming, and antimicrobial activities. In the present review, we have focused on the recently published original research articles on chalcones as a unique antibacterial framework in medicinal chemistry. Chalcones are structurally diverse moieties and can be split into simple and hybrid chalcones, with both having core pharmacophore 1,3-diaryl-2-propen-1-one. Chalc...
Source: Mini Reviews in Medicinal Chemistry - July 27, 2023 Category: Chemistry Authors: Anand Maurya Alka Agrawal Source Type: research