Journal of the Neurological Sciences This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Virology, ecology, epidemiology, pathology, and treatment of eastern equine encephalitis
Eastern equine encephalitis (EEE) was one of the first-recognized neuroinvasive arboviral diseases in North America, and it remains the most lethal. Although EEE is known to have periodic spikes in infection rates, there is increasing evidence that it may be undergoing a change in its prevalence and its public health burden. Numerous factors shape the scope of EEE in humans, and there are important similarities with other emergent viral diseases that have surfaced or strengthened in recent years. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 13, 2024 Category: Neurology Authors: Adeel S. Zubair, Lindsay S. McAlpine, Kevin T. Gobeske Tags: Review Article Source Type: research

Quality of life assessment when considering the introduction of device-assisted therapies in advanced Parkinson's disease: A retrospective observational cross-sectional study
Device-aided therapy (DAT) is an established treatment for improving the quality of life (QOL) in individuals with advanced Parkinson's disease (APD). Criteria for starting DAT, including motor and non-motor symptoms, have been proposed. However, it remains unclear whether QOL differences among patients with APD influence DAT introduction. Therefore, we aimed to investigate QOL differences between patients with and without DAT introduction. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 13, 2024 Category: Neurology Authors: Tatsuya Ueno, Rie Haga, Akira Arai, Masahiko Tomiyama Source Type: research

Identification and characterization of novel ERBB4 variant associated with sporadic amyotrophic lateral sclerosis (ALS)
Amyotrophic Lateral Sclerosis (ALS) is the most common type of motor neuron disease characterized by progressive motor neuron degeneration in brain and spinal cord. Most cases are sporadic in ALS and 5 –10% of cases are familiar.>50 genes are known to be associated with ALS and one of them is ERBB4. In this paper, we report the case of a 53-year-old ALS patient with progressive muscle weakness and fasciculation, but he had no cognitive decline. We performed the next generation sequencing (NGS) and in silico analysis, it predicted a highly pathogenic variant, c.2116  A > G, p.Asn706Asp (N706D) in the ERBB4 gene. (So...
Source: Journal of the Neurological Sciences - January 12, 2024 Category: Neurology Authors: Younghwi Kwon, Minsung Kang, Yu-Mi Jeon, Shinrye Lee, Ho-Won Lee, Jin-Sung Park, Hyung-Jun Kim Source Type: research

Editorial Board
(Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 10, 2024 Category: Neurology Source Type: research

The dark side of the White Matter. Diffuse subcortical White Matter Hypointensity on T2/FLAIR: A systematic review of a frequently underrecognized sign
Many reversible brain MRI abnormalities have been described, among these the most frequently reported are cortical hyperintensities on FLAIR/T2 occurring during seizures. Much less attention has been given to those situations where White Matter goes Dark: subcortical white matter hypointensity on T2/FLAIR. Our aim is to identify the medical condition “Dark White Matter” (DWM) is more frequently associated with. This is the first systematic review on DWM. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 10, 2024 Category: Neurology Authors: Giuseppe Magro, Federico Tosto, Vincenzo Laterza, Olindo Di Benedetto Source Type: research

Recurrent vascular events partially explain association between diabetes and poor prognosis in young ischemic stroke patients
In this study, we aimed to identify factors associated with poor long-term prognosis in young stroke patients. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 10, 2024 Category: Neurology Authors: Mahina Azeem Haja Shareef, Kaavya Narasimhalu, Seyed Ehsan Saffari, Fung Peng Woon, Deidre Anne De Silva Source Type: research

Stroke, HIV and the immune reconstitution inflammatory syndrome in the absence of opportunistic infections
Stroke in people living with HIV (PLWH) has been described to occur soon after the initiation of antiretroviral therapy (ART) possibly related to the Immune Reconstitution Inflammatory Syndrome (IRIS). We sought to investigate whether there was a temporal association between stroke and recent ART initiation in the absence of opportunistic infections (OIs), and to identify risk factors for this. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 8, 2024 Category: Neurology Authors: Eitzaz Sadiq, Sarah Katzew, Jeremy Nel, Grace Tade, Angela Woodiwiss, Gavin Norton, Girish Modi Tags: Clinical short communication Source Type: research

Green space and stroke: A scoping review of the evidence
Rapid global urbanisation has led to a renewed interest in the link between the environment and health. Stroke is a major cause of morbidity and mortality, and there is increased evidence that environmental factors may affect both the incidence and severity of stroke. This review summarises the evidence for relationship between green space exposure and stroke incidence and outcomes. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 7, 2024 Category: Neurology Authors: Mina Whyte, Jeroen Douwes, Annemarei Ranta Source Type: research

The effect of asymptomatic intracranial hemorrhage after mechanical thrombectomy on clinical outcome
This study aimed to address this uncertainty. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 6, 2024 Category: Neurology Authors: Kentaro Suzuki, Takehiro Katano, Shinichiro Numao, Yuji Nishi, Akihito Kutsuna, Takuya Kanamaru, Tomonari Saito, Junya Aoki, Yasuhiro Nishiyama, Kazumi Kimura Source Type: research

Genomics landscape of mitochondrial DNA variations in patients from South Italy affected by mitochondriopathies
Mitochondrial DNA (mtDNA) is a 16,569 base pairs, double-stranded, circular molecule that contains 37 genes coding for 13 subunits of the respiratory chain plus 2 rRNAs and 22 tRNAs. Mutations in these genes have been identified in patients with a variety of disorders affecting every system in the body. The advent of next generation sequencing technologies has provided the possibility to perform the whole mitochondrial DNA sequencing, allowing the identification of disease-causing pathogenic variants in a single platform. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 6, 2024 Category: Neurology Authors: Luigi Citrigno, Antonio Qualtieri, Annamaria Cerantonio, Selene De Benedittis, Olivier Gallo, Gemma Di Palma, Patrizia Spadafora, Francesca Cavalcanti Source Type: research

Congenital tremor and myopathy secondary to novel MYBPC1 variant
Congenital myopathy with tremor (MYOTREM) is a recently described disorder characterized by mild myopathy and a postural and intention tremor present since early infancy. MYOTREM is associated with pathogenic variants in MYBPC1 which encodes slow myosin-binding protein C, a sarcomere protein with regulatory and structural roles. Here, we describe a family with three generations of variably affected members exhibiting a novel variant in MYBPC1 (c.656  T > C, p.Leu219Pro). Among the unique features of affected family members is the persistence of tremor in sleep. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 3, 2024 Category: Neurology Authors: Heather Leduc-Pessah, Ian C. Smith, Kristin D. Kernohan, Marcos Sampaio, Gerd Melkus, Lauren Strasser, Caitlin Chisholm, Lijia Huang, Ilana Hanes, My-An Tran, Sunita Venkateswaran, Katherine Muir, Laurel Charlesworth, Jodi Warman-Chardon Tags: Clinical short communication Source Type: research

Clinical characteristics of stroke in SARS-CoV-2 infected patients in Japan: A prospective nationwide study
We investigated the clinical characteristics and outcomes of stroke in SARS-CoV-2 infected patients in Japan. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 3, 2024 Category: Neurology Authors: Yasuhiro Nishiyama, Susumu Miyamoto, Manabu Sakaguchi, Nobuyuki Sakai, Kensaku Yoshida, Naoki Tokuda, Shunsuke Ichi, Yasuyuki Iguchi, Masatoshi Koga, Ikuya Yamaura, Teruyuki Hirano, Hiroshi Yamagami, Kazumi Kimura Source Type: research

Cockayne syndrome: A pediatric neurodegenerative disorder linking mitochondria to aging
Cockayne syndrome (CS) is characterized by cachectic dwarfism, progressive pigmentary retinopathy, sensorineural hearing loss, microcephaly, and neurological regression. Individuals with this condition also have thin, dry hair, skin photosensitivity, and dental caries. The lack of facial adipose tissue and sunken eyes give “wizened” facial appearance. Wrinkled skin, stooped posture due to joint contractures, cataracts, and premature atherosclerosis resemble normal but accelerated aging. Hence, it is classified under progeria-like or progeroid syndromes. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 3, 2024 Category: Neurology Authors: Mary Kate Hatch, Colleen Donnelly, Pankaj Prasun Source Type: research

Thyroid hormone dysfunction in MOGAD and other demyelinating diseases
Thyroid hormones play a critical role in both neuronal and glial cell functions. Multiple sclerosis (MS) has increased co-occurrence with autoimmune thyroid diseases, and recent studies have suggested a potential link between neuromyelitis optica spectrum disorder (NMOSD) and thyroid hormones. However, no previous studies have examined the relationship between thyroid hormones and myelin oligodendrocyte glycoprotein-associated demyelination (MOGAD). (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 2, 2024 Category: Neurology Authors: Ariel Rechtman, Omri Zveik, Nitsan Haham, Tal Freidman-Korn, Adi Vaknin-Dembinsky Source Type: research

Clinical characteristics of SARS-CoV-2-associated encephalopathy in children: Nationwide epidemiological study
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sometimes triggers acute encephalopathy as a serious neurological complication in children. We previously reported the clinico-radiological findings of SARS-CoV-2-associated encephalopathy. The advent of the SARS-CoV-2 omicron variant led to a marked increase in pediatric patients with coronavirus disease 2019 (COVID-19); however, epidemiological changes with acute encephalopathy according to the emergence of SARS-CoV-2 have not yet been documented. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 2, 2024 Category: Neurology Authors: Mariko Kasai, Hiroshi Sakuma, Yuichi Abe, Ichiro Kuki, Yoshihiro Maegaki, Kei Murayama, Yuka Murofushi, Hiroaki Nagase, Masahiro Nishiyama, Akihisa Okumura, Yasunari Sakai, Hiroko Tada, Masashi Mizuguchi, Jun-ichi Takanashi, the Japanese Pediatric Neuro-C Source Type: research