Journal of the Neurological Sciences This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Intravenous thrombolysis prior to endovascular thrombectomy in elderly stroke patients: An analysis of the National Inpatient Sample database
The effectiveness of intravenous thrombolysis (IVT) prior to endovascular thrombectomy (EVT), also termed bridging thrombolysis, remains uncertain, and there is limited data on its use for elderly patients who may be more prone to hemorrhagic complications. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 13, 2023 Category: Neurology Authors: Huanwen Chen, Mihir Khunte, Marco Colasurdo, Ajay Malhotra, Dheeraj Gandhi Source Type: research

Evaluation and treatment approaches for neurological post-acute sequelae of COVID-19: A consensus statement and scoping review from the global COVID-19 neuro research coalition
Post-acute neurological sequelae of COVID-19 affect millions of people worldwide, yet little data is available to guide treatment strategies for the most common symptoms. We conducted a scoping review of PubMed/Medline from 1/1/2020 –4/1/2023 to identify studies addressing diagnosis and treatment of the most common post-acute neurological sequelae of COVID-19 including: cognitive impairment, sleep disorders, headache, dizziness/lightheadedness, fatigue, weakness, numbness/pain, anxiety, depression and post-traumatic stress di sorder. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 12, 2023 Category: Neurology Authors: Jennifer A. Frontera, Alla Guekht, Ricardo F. Allegri, Mariam Ashraf, Bet ül Baykan, Lucía Crivelli, Ava Easton, David Garcia-Azorin, Raimund Helbok, Jatin Joshi, Julia Koehn, Igor Koralnik, M. Netravathi, Benedict Michael, Annacarmen Nilo, Aynur Özge, Tags: Review Article Source Type: research

No association between SARS-CoV-2 vaccination and ischaemic stroke or high-risk transient ischaemic attack
Initiation of SARS-CoV-2 (Severe acute respiratory syndrome coronavirus type 2) vaccinations aroused scepticism within the general-public about risks including stroke. Our aim was to explore temporal associations between vaccination and cerebrovascular events through an analysis of a prospective large-scale cohort of consecutive stroke and high-risk TIA (transitory ischaemic attack) patients. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 10, 2023 Category: Neurology Authors: Silvia Komarek, Benjamin Dejakum, Kurt Moelgg, Christian Boehme, Anel Karisik, Thomas Toell, Stefan Kiechl, Michael Knoflach, Raimund Pechlaner, Lukas Mayer-Suess Tags: Clinical short communication Source Type: research

Swallowing sound index analysis using electronic stethoscope and artificial intelligence for patients with Parkinson's disease
This study investigated the swallowing sound index in patients with Parkinson's disease (PD). (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 9, 2023 Category: Neurology Authors: Masahiro Nakamori, Yoshitaka Shimizu, Tamayo Takahashi, Megumi Toko, Hidetada Yamada, Yuki Hayashi, Kai Ushio, Kohei Yoshikawa, Aya Hiraoka, Mineka Yoshikawa, Toshikazu Nagasaki, Yukio Mikami, Hirofumi Maruyama Source Type: research

Artificial intelligence and machine learning in aneurysmal subarachnoid hemorrhage: Future promises, perils, and practicalities
Aneurysmal subarachnoid hemorrhage (SAH) is a subtype of hemorrhagic stroke with thirty-day mortality as high as 40%. Given the expansion of Machine Learning (ML) and Artificial intelligence (AI) methods in health care, SAH patients desperately need an integrated AI system that detects, segments, and supports clinical decisions based on presentation and severity. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 9, 2023 Category: Neurology Authors: Saif Salman, Qiangqiang Gu, Rohan Sharma, Yujia Wei, Benoit Dherin, Sanjana Reddy, Rabih Tawk, W. David Freeman Tags: Review Article Source Type: research

Psychological factors and brain magnetic resonance imaging metrics associated with fatigue in persons with multiple sclerosis
Besides demographics and clinical factors, psychological variables and brain-tissue changes have been associated with fatigue in persons with multiple sclerosis (pwMS). Identifying predictors of fatigue could help to improve therapeutic approaches for pwMS.Therefore, we investigated predictors of fatigue using a multifactorial approach. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 9, 2023 Category: Neurology Authors: Stefanie Hechenberger, Birgit Helmlinger, Iris-Katharina Penner, Lukas Pirpamer, Viktoria Fruhwirth, Bettina Heschl, Stefan Ropele, Sebastian Wurth, Anna Damulina, Sebastian Eppinger, Rina Demjaha, Michael Khalil, Daniela Pinter, Christian Enzinger Source Type: research

Autoimmune and paraneoplastic neurological disorders: A review of relevant neuroimaging findings
Paraneoplastic neurologic syndromes (PNS) and autoimmune encephalitis (AIE) are immune-mediated disorders. PNS is linked to cancer, while AIE may not Their clinical manifestations and imaging patterns need further elucidation. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 7, 2023 Category: Neurology Authors: Sema Akkus, Mahmoud Elkhooly, Suban Amatya, Kriti Shrestha, Kanika Sharma, Yusuf Kagzi, Erum Khan, Rajesh Gupta, Amanda L. Piquet, Shruti Jaiswal, Sijin Wen, Michaela Tapia, Rohan Samant, Sri Raghav Sista, Shitiz Sriwastava Tags: Review Article Source Type: research

Abnormal network connections to early visual cortex in posterior cortical atrophy
Posterior Cortical Atrophy (PCA), a visual variant of Alzheimer's disease, initially manifests with higher-order visual disorders and parieto/temporo-occipital atrophy. Recent studies have shown remote functional impairment in both distant brain networks and along the calcarine sulcus (V1). Functional alteration in the calcarine differs along its length, reflecting center to periphery visual space differences. Herein, we aim to connect between these two sets of findings by looking at the retinotopic patterns of functional connectivity between large-scale brain networks and V1, comparing patients with normally sighted subje...
Source: Journal of the Neurological Sciences - October 5, 2023 Category: Neurology Authors: Atira Bick, Ayelet McKyton, Glick-Shames Haya, Netaniel Rein, Netta Levin Source Type: research

Lysine 117 on ataxin-3 modulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3
Ataxin-3 (Atxn3) is a deubiquitinase with a polyglutamine (polyQ) repeat tract whose abnormal expansion causes the neurodegenerative disease, Spinocerebellar Ataxia Type 3 (SCA3; also known as Machado-Joseph Disease). The ubiquitin chain cleavage properties of Atxn3 are enhanced when the enzyme is itself ubiquitinated at lysine (K) at position 117: in vitro, K117-ubiqutinated Atxn3 cleaves poly-ubiquitin markedly more rapidly compared to its unmodified counterpart. How polyQ expansion causes SCA3 remains unclear. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 5, 2023 Category: Neurology Authors: Jessica R. Blount, Nikhil C. Patel, Kozeta Libohova, Autumn L. Harris, Wei-Ling Tsou, Alyson Sujkowski, Sokol V. Todi Source Type: research

Increased risk of myocardial infarction in amyotrophic lateral sclerosis: A nationwide cohort study in South Korea
The risk of myocardial infarction (MI), the major form of CVD, in amyotrophic lateral sclerosis (ALS) is currently unknown. We investigated the risk of MI in ALS and analyzed the effect of ALS-related physical disability on the risk of MI using the Korean National Health Insurance Service database. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 5, 2023 Category: Neurology Authors: Soonwook Kwon, Bongseong Kim, Kyung-Do Han, Wonyoung Jung, Eun Bin Cho, Jeong Hoon Yang, Dong Wook Shin, Ju-Hong Min Source Type: research

Aquaporin-4-IgG positive neuromyelitis optica spectrum disorder in a paraneoplastic context
The association between aquaporin-4-immunoglobulin-G-positive neuromyelitis optica spectrum disorder (AQP4-IgG-NMOSD) and cancer via a plausible immunological response has been reported. Here, we investigated the frequency of cancer in a large cohort of patients with AQP4-IgG-NMOSD. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 4, 2023 Category: Neurology Authors: Jae-Won Hyun, Na Young Park, Min Jeong Kim, Haeun Kim, Ki Hoon Kim, Su-Hyun Kim, Ho Jin Kim Tags: Clinical short communication Source Type: research

The role of the kynurenine pathway in cognitive functioning after stroke: A prospective clinical study
The kynurenine pathway is the main metabolic pathway of tryptophan degradation and has been associated with stroke and impaired cognitive functioning, but studies on its role in post-stroke cognitive impairment (PSCI) are scarce. We aimed to investigate associations between metabolites of the kynurenine pathway at baseline and post-stroke cognitive functioning over time. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 3, 2023 Category: Neurology Authors: Lieke Bakker, Inez H.G.B. Ramakers, J.P.M. Eussen Simone, Kyonghwan Choe, Daniel L.A. van den Hove, Gunter Kenis, Bart P.F. Rutten, Robert J. van Oostenbrugge, Julie Staals, Arve Ulvik, Per M. Ueland, Frans R.J. Verhey, Sebastian K öhler Source Type: research

Non-steroidal anti-inflammatory drug use and markers of Parkinson's disease progression: A retrospective cohort study
Previous studies demonstrated reduced incidence of Parkinson's disease (PD) with regular non-steroidal anti-inflammatory drug (NSAID) exposure, particularly ibuprofen. No studies have investigated the impact of NSAID exposure on markers of disease progression for established PD. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 3, 2023 Category: Neurology Authors: Greg Kuhlman, Peggy Auinger, Sarah Duff-Canning, Anthony Lang, Caroline Tanner, Connie Marras Source Type: research

Inherited chromosomally integrated HHV6 in an adult who presented with a generalized tonic clonic seizure
HHV6 is a ubiquitous beta-herpesvirus with>95% of the population found to be seropositive in early adulthood. This virus infects a variety of host cells with a lifelong latency. HHV6 with a unique mechanism of latency, integrates its genome into the telomeres of latently infected cells as well as into the germline chromosomes, thus resulting in individuals carrying a copy of the HHV6 genome in every nucleated cell . Inherited chromosomally integrated HHV6 (iciHHV6) has been observed in 1% of the human population. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 3, 2023 Category: Neurology Authors: Alaa Atamna, Guy Raphaeli, Sara Dovrat, Alon Grosman, Jihad Bishara Source Type: research

Rest-activity patterns associated with delirium in patients with intracerebral hemorrhage
Delirium is an acute cognitive disturbance frequently characterized by abnormal psychomotor activity and sleep-wake cycle disruption. However, the degree to which delirium affects activity patterns in the acute period after stroke is unclear. We aimed to examine these patterns in a cohort of patients with intracerebral hemorrhage (ICH). (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 3, 2023 Category: Neurology Authors: Michael E. Reznik, Noa Mintz, Scott Moody, Jonathan Drake, Seth A. Margolis, James L. Rudolph, Jamie N. LaBuzetta, Biren B. Kamdar, Richard N. Jones Source Type: research