Journal of the Neurological Sciences This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Deep vein thrombosis and its risk factors in neurodegenerative diseases: A markedly higher incidence in Parkinson's disease
Information on the incidence and risk factors of deep vein thrombosis (DVT) in neurodegenerative diseases is limited. We aimed to determine the incidence of DVT among neurodegenerative disorders (amyotrophic lateral sclerosis [ALS], Parkinson's disease [PD], multiple system atrophy [MSA], and progressive supranuclear palsy [PSP]-corticobasal syndrome [CBS]) and the risk factors for the development of DVT. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 22, 2024 Category: Neurology Authors: Takahiro Takeda, Akihiro Koreki, Sayuri Kokubun, Yumiko Saito, Ai Ishikawa, Sagiri Isose, Kimiko Ito, Kimihito Arai, Kazuo Kitagawa, Satoshi Kuwabara, Kazuhiro Honda Source Type: research

Avocational exposure associations with ALS risk, survival, and phenotype: A Michigan-based case-control study
Environmental exposures strongly influence ALS risk and identification is needed to reduce ALS burden. Participation in hobbies and exercise may alter ALS risk and phenotype, warranting an assessment to understand their contribution to the ALS exposome. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 22, 2024 Category: Neurology Authors: Stephen A. Goutman, Jonathan Boss, Dae Gyu Jang, Caroline Piecuch, Hasan Farid, Madeleine Batra, Bhramar Mukherjee, Eva L. Feldman, Stuart A. Batterman Source Type: research

Neurological patients confronting climate change: A potential role for the glymphatic system and sleep
Interest in the health consequences of climate change (global warming, heatwaves) has increased in the neurological community. This review addresses the impact of elevated ambient temperatures and heatwaves on patients with neurological and mental health disorders, including multiple sclerosis, synucleinopathies, dementia, epilepsies, mental health, and stroke. Patients with such conditions are highly vulnerable during heatwaves because of functional disorders affecting sleep, thermoregulation, autonomic system reactivity, mood, and cognitive ability. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 22, 2024 Category: Neurology Authors: Jacques Reis, Alain Buguet, Manny Radomski, Alex Buoite Stella, Teresa Corona V ásquez, Peter S. Spencer Source Type: research

Proton pump inhibitors and amyotrophic lateral sclerosis: A case-control study
Proton pump inhibitors (PPIs) have been investigated as a risk factor for neurodegenerative diseases, in particular in Alzheimer's and Parkinson's disease, strongly supporting this association (results are summarized in Table 1). (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 20, 2024 Category: Neurology Authors: Maria Eduarda Cardoso Tortorella, In ês Alves, Marta Gromicho, Miguel Oliveira Santos, Mamede de Carvalho Source Type: research

Fast but not furious: Rapid ocrelizumab infusion as a strategy to optimize multiple sclerosis patients' management
We describe our single-center experience with ocrelizumab (OCR) rapid infusion (OCR-RI) in patients with MS (pwMS). (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 20, 2024 Category: Neurology Authors: Chiara Zanetta, Patricia Faustino, Simone Guerrieri, Agostino Nozzolillo, Angela Genchi, Chiara Bucca, Maria A. Rocca, Lucia Moiola, Massimo Filippi Tags: Clinical short communication Source Type: research

Amyloid accumulation in cases of suspected comorbid cerebral amyloid angiopathy and isolated cortical venous thrombosis
The differentiation of isolated cortical venous thrombosis (ICVT) from cerebral amyloid angiopathy (CAA) can be difficult because both diseases share similar neurological symptoms and imaging findings. N-methyl-11C-2-(4 ′-methylaminophenyl)-6-hydroxybenzo-thiazole (11C-PiB) positron emission tomography (PET) functions as a diagnostic modality for CAA by detecting amyloid deposition. The present prospective study evaluated amyloid deposition using 11C-PiB-PET in consecutive patients with suspected ICVT. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 20, 2024 Category: Neurology Authors: Yuya Kobayashi, Kotaro Hiraoka, Ryo Itabashi, Takuya Saito, Yuichi Kawabata, Yukako Yazawa, Yoshihito Funaki, Shozo Furumoto, Nobuyuki Okamura, Katsutoshi Furukawa, Aiko Ishiki, Hiroyuki Arai, Kazuhiko Yanai, Manabu Tashiro, Yoshiki Sekijima Source Type: research

The influence of limbic-predominant age-related TDP-43 encephalopathy on argyrophilic grain disease: A voxel-based morphometry analysis of pathologically confirmed cases
This study aims to investigate the morphological impact of LATE-NC on AGD through voxel-based morphometry (VBM) technique. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 19, 2024 Category: Neurology Authors: Shohei Inui, Daita Kaneda, Keita Sakurai, Satoru Morimoto, Yuto Uchida, Osamu Abe, Yoshio Hashizume Source Type: research

Crosstalk between gut microbiome and neuroinflammation in pathogenesis of HIV-associated neurocognitive disorder
HIV-associated neurocognitive disorder (HAND) has become a chronic neurodegenerative disease affecting the quality of life in people living with HIV (PLWH). Despite an established association between HAND and neuroinflammation induced by HIV proteins (gp120, Tat, Rev., Nef, and Vpr), the pathogenesis of HAND remains to be fully elucidated. Accumulating evidence demonstrated that the gut microbiome is emerging as a critical regulator of various neurodegenerative diseases (e.g., Parkinson's disease, Alzheimer's disease), suggesting that the crosstalk between the gut microbiome and neuroinflammation may contribute to the deve...
Source: Journal of the Neurological Sciences - January 18, 2024 Category: Neurology Authors: Xue Chen, Jiaqi Wei, Yang Zhang, Yulin Zhang, Tong Zhang Tags: Review Article Source Type: research

High temperature requirement A1 and macrophage migration inhibitory factor in the cerebrospinal fluid; a potential marker of conversion from relapsing-remitting to secondary progressive multiple sclerosis
Predictive and prognostic biomarkers for multiple sclerosis (MS) remain a significant gap in MS diagnosis and treatment monitoring. Currently, there are no timely markers to diagnose the transition to secondary progressive MS (SPMS). (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 14, 2024 Category: Neurology Authors: Simone Hj æresen, Eirikur Benedikz, Tobias Sejbaek, Markus Axelsson, Lenka Novakova, Mengliang Zhang, Jan Lycke, Zsolt Illes, Åsa Fex-Svenningsen Tags: Clinical short communication Source Type: research

Long-term clinical course and treatment outcomes of individuals with Nodding Syndrome
The objectives of this study were to describe the long-term clinical course and treatment outcomes of individuals suffering from Nodding Syndrome. In addition, we aimed to provide a comprehensive characterization of the epileptological and social features of patients with Nodding Syndrome.From 11/2014 to 4/2015, we conducted a hospital-based, cross-sectional and observational study in Mahenge, Tanzania. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 14, 2024 Category: Neurology Authors: Josua Kegele, Thomas Wagner, Teresa Kowenski, Matthias Wiesmayr, Christian Gatterer, Michael Alber, Wiliam Matuja, Erich Schmutzhard, Holger Lerche, Andrea S. Winkler Source Type: research

Free-water diffusion magnetic resonance imaging under selegiline treatment in Parkinson's disease
Monoamine oxidase type B inhibitors, including selegiline, are established as anti-Parkinsonian Drugs. Inhibition of monoamine oxidase type B enzymes might suppress the inflammation because of inhibition to generate reactive oxygen species. However, its effect on brain microstructure remains unclear. The aim of this study is to elucidate white matter and substantia nigra (SN) microstructural differences between Patients with Parkinson's disease with and without selegiline treatment by two independently recruited cohorts. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 13, 2024 Category: Neurology Authors: Haruka Takeshige-Amano, Taku Hatano, Koji Kamagata, Christina Andica, Takashi Ogawa, Atsuhiko Shindo, Wataru Uchida, Wataru Sako, Shinji Saiki, Yasushi Shimo, Genko Oyama, Atsushi Umemura, Masanobu Ito, Masaaki Hori, Shigeki Aoki, Nobutaka Hattori Source Type: research

Choroid plexus volume as a marker of retinal atrophy in relapsing remitting multiple sclerosis
To evaluate choroid plexus (CP) volume as a biomarker for predicting clinical disability and retinal layer atrophy in relapsing remitting multiple sclerosis (RRMS). (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 13, 2024 Category: Neurology Authors: Muhammad F. Raghib, Fen Bao, Mahmoud Eklhooly, Evanthia Bernitsas Source Type: research

Virology, ecology, epidemiology, pathology, and treatment of eastern equine encephalitis
Eastern equine encephalitis (EEE) was one of the first-recognized neuroinvasive arboviral diseases in North America, and it remains the most lethal. Although EEE is known to have periodic spikes in infection rates, there is increasing evidence that it may be undergoing a change in its prevalence and its public health burden. Numerous factors shape the scope of EEE in humans, and there are important similarities with other emergent viral diseases that have surfaced or strengthened in recent years. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 13, 2024 Category: Neurology Authors: Adeel S. Zubair, Lindsay S. McAlpine, Kevin T. Gobeske Tags: Review Article Source Type: research

Quality of life assessment when considering the introduction of device-assisted therapies in advanced Parkinson's disease: A retrospective observational cross-sectional study
Device-aided therapy (DAT) is an established treatment for improving the quality of life (QOL) in individuals with advanced Parkinson's disease (APD). Criteria for starting DAT, including motor and non-motor symptoms, have been proposed. However, it remains unclear whether QOL differences among patients with APD influence DAT introduction. Therefore, we aimed to investigate QOL differences between patients with and without DAT introduction. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - January 13, 2024 Category: Neurology Authors: Tatsuya Ueno, Rie Haga, Akira Arai, Masahiko Tomiyama Source Type: research

Identification and characterization of novel ERBB4 variant associated with sporadic amyotrophic lateral sclerosis (ALS)
Amyotrophic Lateral Sclerosis (ALS) is the most common type of motor neuron disease characterized by progressive motor neuron degeneration in brain and spinal cord. Most cases are sporadic in ALS and 5 –10% of cases are familiar.>50 genes are known to be associated with ALS and one of them is ERBB4. In this paper, we report the case of a 53-year-old ALS patient with progressive muscle weakness and fasciculation, but he had no cognitive decline. We performed the next generation sequencing (NGS) and in silico analysis, it predicted a highly pathogenic variant, c.2116  A > G, p.Asn706Asp (N706D) in the ERBB4 gene. (So...
Source: Journal of the Neurological Sciences - January 12, 2024 Category: Neurology Authors: Younghwi Kwon, Minsung Kang, Yu-Mi Jeon, Shinrye Lee, Ho-Won Lee, Jin-Sung Park, Hyung-Jun Kim Source Type: research