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Ischemic stroke patients with low DWI ASPECTS scores require puncture to recanalization within 30  min for large vessel occlusion
The clinical benefits of faster recanalization in acute large vessel occlusion are well recognized, but the optimal procedure time remains uncertain. The aim of this study was to identify patient characteristics that necessitate puncture-to-recanalization (P-R) time within 30  min to achieve favorable outcome. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 28, 2023 Category: Neurology Authors: Tomohide Yoshie, Toshihiro Ueda, Yasuhiro Hasegawa, Masataka Takeuchi, Masafumi Morimoto, Yoshifumi Tsuboi, Ryoo Yamamoto, Shogo Kaku, Junichi Ayabe, Takekazu Akiyama, Daisuke Yamamoto, Kentaro Mori, Hiroshi Kagami, Hidemichi Ito, Hidetaka Onodera, Yasuyu Source Type: research

The role of optic nerve sheath ultrasonography in increased intracranial pressure: A systematic review and meta analysis
To review the optimal diagnostic cut-off of ultrasonographic optic nerve sheath diameter (ONSD) in the diagnosis of increased intracranial pressure (IICP). (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 28, 2023 Category: Neurology Authors: David Berhanu, Joana Cardoso Ferreira, Lu ís Abegão Pinto, Diana Aguiar de Sousa, Lia Lucas Neto, Joana Tavares Ferreira Tags: Review Article Source Type: research

Herpes simplex virus 2 serology is associated with thinner whole-brain cortex in community-dwelling older adults
In this study, we sought to determine the cross-sectional relationship between prior exposure to cytomegalovirus, herpes simplex viruses 1 and 2, Chlamydia pneumoniae, and Helicobacter pylori and three magnetic resonance imaging (MRI) signatures (whole-brain cortical thickness, a previously validated AD signature, and hippocampal volume) in 455 NOMAS participants. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 28, 2023 Category: Neurology Authors: Jackson A. Roberts, Mitchell S.V. Elkind, Minghua Liu, Clinton B. Wright, Tatjana Rundek, Jose Gutierrez Source Type: research

Environmental factors and stroke: Risk and prevention
Stroke is a leading cause of death and adult disability globally. In addition to traditional risk factors, environmental risk factors have emerged over the recent past and are becoming increasingly important. The disproportionate rise of stroke incidence in low- and middle-income countries has been attributed, at least in part, to environmental factors. This narrative review provides details on the interplay between the environment and health generally and stroke specifically, covering topics including air pollution, atmospheric brown clouds, desert dust storms, giant wildfires, chemical contamination, biological aggressor...
Source: Journal of the Neurological Sciences - October 28, 2023 Category: Neurology Authors: Annemarei Ranta, Serefnur Ozturk, Mohammad Wasay, Maurice Giroud, Yannick B éjot, Jacques Reis Source Type: research

Environmental neurology: Concepts and short history of an interdisciplinary approach to etiology, treatment and prevention
Environmental Neurology (EN), a sub-discipline of Neurology and Neurological Sciences, favors an interdisciplinary collaboration allowing a holistic approach to understanding the impact of environmental factors on the nervous system and their relationship with neurological diseases. Several examples of diseases and conditions show the large scope of subjects addressed by EN. The EN sub-discipline focuses on both individual and population issues thus joining patient care and public health, respectively. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 28, 2023 Category: Neurology Authors: Jacques Reis, Alain Buguet, Gustavo C. Rom án, Peter S. Spencer Source Type: research

Heatwaves and human sleep: Stress response versus adaptation
The World Meteorological Organization considers a heatwave as “a period of statistically unusual hot weather persisting for a number of days and nights”. Accompanying the ongoing global climate change, sharp heatwave bouts occur worldwide, growing in frequency and intensity, and beginning earlier in the season. Heatwaves exacerbate the risk of heat-related illnesses, hence human morbidity and mortality, particularly in vulnerable elderly and children. Heat-related illnesses present a continuum from normothermic (prickly heat, heat edema, heat cramps, heat tetany) to hyperthermic syndromes (from heat syncope and heat ex...
Source: Journal of the Neurological Sciences - October 28, 2023 Category: Neurology Authors: Alain Buguet, Manny W. Radomski, Jacques Reis, Peter S. Spencer Source Type: research

Sleep and global warming: How will we sleep when the Earth is hotter?
Societal concern about climate change and global warming has grown worldwide along with the concomitant awareness that health will be impacted deeply. Among living beings, humans have quite large capacities for adaptation to varied temperature conditions. Despite their tropical origin, they live under all Earth climates, such as polar, temperate, altitude, arid, and tropical climates, using a wide range of behavioral and physiological adaptive responses. We address the adaptive abilities of human sleep-wake regulation and its interplay with thermoregulation under different natural climates. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 27, 2023 Category: Neurology Authors: Alain Buguet, Jacques Reis, Manny W. Radomski Source Type: research

Pre-existing neurological conditions and COVID-19 co-infection: Data from systematic reviews, meta-analyses, and scoping reviews
Pre-existing neurological diseases have been identified as risk factors for severe COVID-19 infection and death. There is a lack of comprehensive literature review assessing the relationship between pre-existing neurological conditions and COVID-19 outcomes. Identification of high risk groups is critical for optimal treatment and care. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 27, 2023 Category: Neurology Authors: Abhilasha P. Boruah, Kiran T. Thakur, Sachin P. Gadani, Kavita U. Kothari, Mashina Chomba, Alla Guekht, Kimia Heydari, Fan Kee Hoo, Soonmyung Hwang, Benedict D. Michael, Maya V. Pandit, Carlos Pardo-Villamizar, Kameshwar Prasad, Zomer Sardar, Katrin Seehe Source Type: research

A prospective cohort study of familial versus sporadic essential tremor cases: Do clinical features evolve differently across time?
Although essential tremor (ET) is often divided into familial and sporadic cases, few data compare the evolution of clinical features in these groups over time. Leveraging data from a prospective, longitudinal study, we present analyses of the evolution of a broad range of cognitive, motor (i.e., tremor, tandem gait) and other features (e.g., disability) of ET. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 25, 2023 Category: Neurology Authors: Diane S. Berry, Stephanie Cosentino, Elan D. Louis Source Type: research

Case series: Downbeat nystagmus in SCA27B
Spinocerebellar ataxia (SCA) 27B, first reported in late 2022, is caused by the abnormal expansion of GAA repeats in the first intron of the FGF14 gene, which encodes the fibroblast growth factor 14. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 25, 2023 Category: Neurology Authors: Shinichi Shirai, Keiichi Mizushima, Keishi Fujiwara, Eriko Koshimizu, Masaaki Matsushima, Satoko Miyatake, Ikuko Iwata, Hiroaki Yaguchi, Naomichi Matsumoto, Ichiro Yabe Tags: Clinical short communication Source Type: research

Accruing real-world data confirm that SARS-CoV-2 vaccination is not associated with stroke
Since its outbreak in December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected 770,563,467 individuals worldwide, while almost 1% of them had died due to coronavirus disease 2019 (COVID-19) [1]. Despite this ordeal, it seems that the humanity was able to tackle the COVID-19 pandemic, with the World Health Organization declaring on May 5th, 2023 the end of COVID-19 as a global health emergency. It is without doubt that the large-scale implementation of vaccination programs against SARS-CoV-2, with more than 5 billion persons being vaccinated with at least one dose worldwide [1], has been inst...
Source: Journal of the Neurological Sciences - October 24, 2023 Category: Neurology Authors: Lina Palaiodimou Source Type: research

Prevention of venous thromboembolism in acute spontaneous intracerebral haemorrhage: A survey of opinion
People immobilized following acute spontaneous intracerebral haemorrhage (ICH) are at risk of venous thromboembolism (VTE) but the role of short-term prophylactic anticoagulation remains uncertain. We surveyed UK clinical practice and opinion regarding preventing VTE after ICH. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 24, 2023 Category: Neurology Authors: Rom Mendel, Nadir Abdelhameed, Rustam Al-Shahi Salman, Hannah Cohen, Dar Dowlatshahi, Nicholas Freemantle, Maurizio Paciarioni, Adrian Parry-Jones, Christopher Price, Nikola Sprigg, David J. Werring Source Type: research

Rare causes of dystonia-parkinsonism with cognitive impairment, behavioral abnormalities, and voiceless whispering stereotypies: Describing the long-term evolution of the neurological phenotype in a patient with the PSEN2 Ile149Thr variant
Genetic variants in Presenilin 1 (PSEN1) and Presenilin 2 (PSEN2) are associated with autosomal dominant forms of Alzheimer's disease (AD) [1], as potentially implicated in dysfunctional gamma-secretase activity in amyloid-beta processing [2].>200 variants in PSEN1 and 68 in PSEN2 have been described [3] [http://www.molgen.ua.ac.be/admutations]. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 20, 2023 Category: Neurology Authors: Luigi Michele Romito, Sara Prioni, Arianna Braccia, Marcella Catania, Antonio Emanuele Elia, Francesco Dondi, Silvia Lucchini, Francesco Bertagna, Sylvie H.M.J. Piacentini, Roberto Eleopra, Giuseppe Di Fede Source Type: research

Intravenous thrombolysis prior to endovascular thrombectomy in elderly stroke patients: An analysis of the National Inpatient Sample database
The effectiveness of intravenous thrombolysis (IVT) prior to endovascular thrombectomy (EVT), also termed bridging thrombolysis, remains uncertain, and there is limited data on its use for elderly patients who may be more prone to hemorrhagic complications. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 13, 2023 Category: Neurology Authors: Huanwen Chen, Mihir Khunte, Marco Colasurdo, Ajay Malhotra, Dheeraj Gandhi Source Type: research

Evaluation and treatment approaches for neurological post-acute sequelae of COVID-19: A consensus statement and scoping review from the global COVID-19 neuro research coalition
Post-acute neurological sequelae of COVID-19 affect millions of people worldwide, yet little data is available to guide treatment strategies for the most common symptoms. We conducted a scoping review of PubMed/Medline from 1/1/2020 –4/1/2023 to identify studies addressing diagnosis and treatment of the most common post-acute neurological sequelae of COVID-19 including: cognitive impairment, sleep disorders, headache, dizziness/lightheadedness, fatigue, weakness, numbness/pain, anxiety, depression and post-traumatic stress di sorder. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - October 12, 2023 Category: Neurology Authors: Jennifer A. Frontera, Alla Guekht, Ricardo F. Allegri, Mariam Ashraf, Bet ül Baykan, Lucía Crivelli, Ava Easton, David Garcia-Azorin, Raimund Helbok, Jatin Joshi, Julia Koehn, Igor Koralnik, M. Netravathi, Benedict Michael, Annacarmen Nilo, Aynur Özge, Tags: Review Article Source Type: research