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High brain natriuretic peptide level is associated with severe stroke in patients taking oral anticoagulants: A sub-analysis of the PASTA registry study
In this study, we aimed to investigate the association between stroke severity at admission and BNP levels. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 15, 2024 Category: Neurology Authors: Satoshi Suda, Yasuyuki Iguchi, Yoshiki Yagita, Takao Kanzawa, Seiji Okubo, Shigeru Fujimoto, Yu Kono, Kazumi Kimura, on behalf of PASTA Investigators Source Type: research

Editorial Board
(Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 14, 2024 Category: Neurology Source Type: research

Real world data analysis of frontotemporal dementia: Implications for future clinical research
Frontotemporal dementia (FTD) is a progressive decline of cognitive abilities associated with other neuropsychiatric comorbidities. A real-world data (RWD) analysis of a large electronic healthcare records (EHR) database identified the comorbidities of FTD. Deidentified EHRs in the TriNetX Network database from>150,000,000 individuals in the United States established an FTD Cohort (ICD-10 Code G31.0) of adult patients who visited a healthcare provider in 2022. The non-FTD cohort were age-matched individuals who had not received a diagnosis of ICD-10 Code G31.0, and who had visited a healthcare provider in 2022. (Source: Jo...
Source: Journal of the Neurological Sciences - February 13, 2024 Category: Neurology Authors: Stephen J. Peroutka Source Type: research

Spatial colocalization of imaging markers in iatrogenic cerebral amyloid angiopathy with the site of surgery: A metaanalysis
Iatrogenic cerebral amyloid angiopathy (iCAA) is a rare form of CAA. Imaging features are overlapping with spontaneous CAA. However, in iCAA imaging features have not been systematically described so far. The aim of this metaanalysis was to evaluate if any of the described imaging features showed colocalization with the initial site of surgery. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 13, 2024 Category: Neurology Authors: Ulf Jensen-Kondering Tags: Review Article Source Type: research

Lower exposure to risk factors for stroke in green spaces in comparison with metropolitan areas. The importance of education and information to reduce the difference
We would like to congratulate White et al. for their interesting study [1]. White et al. performed a systematic review to analyze a possible correlation between living in a “green space environment” and the prevalence of stroke and clinical outcomes. The Authors found a consistent evidence indicating a protective association between green space exposure and disability and stroke-related deaths with mortality hazard ratios between 0.66 and 0.95. They concluded that the association between living in a green space and reduced prevalence of stroke may be related with several factors, including reduced noise and air polluti...
Source: Journal of the Neurological Sciences - February 13, 2024 Category: Neurology Authors: Antonio V. Sterpetti, Raimondo Gabriele, Immacolata Iannone, Luca Di Source Type: research

Clinical characteristics of patients with Parkinson's disease with reduced 123I-Metaiodobenzylguanidine uptake in the major salivary glands and heart
Parkinson's disease (PD) shows cardiac sympathetic denervation (SD) in 123I-metaiodbezylguanidine (MIBG) scintigraphy. Recently, SD in the major salivary glands (MSG-SD) was introduced as a possible radiological feature of PD. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 12, 2024 Category: Neurology Authors: Junya Ebina, Sunao Mizumura, Harumi Morioka, Mari Shibukawa, Junpei Nagasawa, Masaru Yanagihashi, Takehisa Hirayama, Nobutomo Ishii, Yukio Kobayashi, Akira Inaba, Satoshi Orimo, Osamu Kano Source Type: research

Factors and brain imaging features associated with cognition in oldest-old patients with Alzheimer-type dementia
The underlying pathophysiology of cognitive dysfunction in oldest-old patients with Alzheimer-type dementia (AD) has not been clarified to date. We aimed to determine the factors and brain imaging features associated with cognition in oldest-old patients with AD. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 10, 2024 Category: Neurology Authors: Haruo Hanyu, Yumi Koyama, Kazuki Umekida, Toshimitsu Momose, Sadayoshi Watanabe, Tomohiko Sato Source Type: research

Natalizumab extended interval dosing: What about wearing-off effect?
This study aimed to evaluate the impact of EID in WO in MS patients under natalizumab. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 10, 2024 Category: Neurology Authors: Catarina Bernardes, Catarina Fernandes, Carolina Cunha, Carla Nunes, Carmo Mac ário, Lívia Sousa, Sónia Batista, Inês Correia Source Type: research

Impaired sleep is associated with tau deposition on 18F-flortaucipir PET and accelerated cognitive decline, accounting for medications that affect sleep
Impaired sleep is commonly associated with Alzheimer's disease (AD), although the underlying mechanisms remain unclear. Furthermore, the moderating effects of sleep-affecting medications, which have been linked to AD pathology, are incompletely characterized. Using data from the Alzheimer's Disease Neuroimaging Initiative, we investigated whether a medical history of impaired sleep, informant-reported nighttime behaviors, and sleep-affecting medications are associated with beta-amyloid and tau deposition on PET and cognitive change, cross-sectionally and longitudinally. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 8, 2024 Category: Neurology Authors: Ryan T. Kim, Liangdong Zhou, Yi Li, Ana Krieger, Anna S. Nordvig, Tracy Butler, Mony J. de Leon, Gloria C. Chiang, the Alzheimer's Disease Neuroimaging Initiative Source Type: research

Editorial on an autoencoder algorithm for the prediction of stroke patients with left ventricular thrombus (LVT)
In this research paper, Hargreaves et al., used an autoencoder model to classify the patients with left ventricular thrombus for high or low risk of stroke. The authors examined various factors to elucidate which ones had pivotal roles in predicting the risk factors for stroke. They concluded that individuals with a previous history of stroke, those who experienced transient ischemic strokes, and those who took anticoagulation medicine for longer durations were more likely to be categorized as being at a high risk of stroke. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 8, 2024 Category: Neurology Authors: Muhammad Khaliq, Ibraheem Shaikh, Salil Soman Source Type: research

Current opinions and practices in post-stroke movement disorders: Survey of movement disorders society members
Post-stroke movement disorders (PSMD) encompass a wide array of presentations, which vary in mode of onset, phenomenology, response to treatment, and natural history. There are no evidence-based guidelines on the diagnosis and treatment of PSMD. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 7, 2024 Category: Neurology Authors: Federico Rodriguez-Porcel, Harini Sarva, Juho Joutsa, Cristian Falup-Pecurariu, Aparna Wagle Shukla, Raja Mehanna, Katarzyna Śmiłowska, Giuseppe Lanza, Saša R. Filipović, Ali Shalash, Margaret Ferris, Joseph Jankovic, Alberto J. Espay, Sanjay Pandey, Source Type: research

Disease-modifying therapy use and health resource utilisation associated with multiple sclerosis over time: A retrospective cohort study from Alberta, Canada
Estimating multiple sclerosis (MS) prevalence and incidence, and assessing the utilisation of disease-modifying therapies (DMTs) and healthcare resources over time is critical to understanding the evolution of disease burden and impacts of therapies upon the healthcare system. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 6, 2024 Category: Neurology Authors: Erin F. Balcom, Penelope Smyth, Mahesh Kate, Khanh Vu, Karen J.B. Martins, Sylvia Aponte-Hao, Huong Luu, Lawrence Richer, Tyler Williamson, Scott W. Klarenbach, Jennifer A. McCombe Source Type: research

The future of brain health advocacy: Recommendations of the 2023 World Congress of Neurology advocacy panel
Below we share insights and recommendations on neurological advocacy emanating from two panel discussions held at the World Federation of Neurology's (WFN's) 2023 World Congress of Neurology (WCN) that took place in Montreal, Canada, in October 2023. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 2, 2024 Category: Neurology Authors: Mohammad Wasay, Wolfgang Grisold, Tissa Wijeratne, Walter Struhal, Safa Younis, On behalf of the World Federation of Neurology Source Type: research

Efficacy and safety outcomes of Tenecteplase versus Alteplase for thrombolysis of acute ischemic stroke: A meta-analysis of 9 randomized controlled trials
In recent years, Tenecteplase (TNK), a genetically modified variant of alteplase, has been verified as a potential substitute for alteplase in the reperfusion therapy of acute ischemic stroke (AIS). Given the emergence of new randomized controlled trials (RCTs) of this subject, a meta-analysis was conducted to evaluate the present comparative evidence regarding the efficacy and safety outcomes of TNK and alteplase in thrombolysis for AIS. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 2, 2024 Category: Neurology Authors: Yue Wang, Xiuying Cai, Qi Fang, Juehua Zhu Tags: Review Article Source Type: research

The future of brain health advocacy: Recommendations of the 2023 world congress of neurology - advocacy panel
Below we share insights and recommendations on neurological advocacy emanating from two panel discussions held at the World Federation of Neurology's (WFN's) 2023 World Congress of Neurology (WCN) that took place in Montreal, Canada, in October 2023. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - February 2, 2024 Category: Neurology Authors: Mohammad Wasay, Wolfgang Grisold, Tissa Wijeratne, Walter Struhal, Safa Younis, On behalf of the World Federation of Neurology Source Type: research