Development of lymph node metastasis-related prognostic markers in breast cancer
CONCLUSIONS: We built a prognostic model of BC based on LNM-related genes, proffering evaluation for prognosis and precise cure of BC.SIGNIFICANCE: At present, the genes related to lymph node metastasis in BC are still largely unknown and need to be further explored. Searching for potential lymph node metastasis-related genes of BC will provide meaningful biomarkers for BC treatment. Based on TCGA-BRCA data, we established an effective 11-gene prognostic risk model that could predict patient outcomes independently. Our model could classify BC patients and distinguish patients with poor prognosis effectively. Besides, the f...
Source: Journal of Proteomics - November 8, 2023 Category: Biochemistry Authors: Yinhua Pan Quanqing Zou Wu Yin Zhen Huang Yingzhu Zhao Zongming Mo Lihui Li Jianrong Yang Source Type: research
Development of lymph node metastasis-related prognostic markers in breast cancer
CONCLUSIONS: We built a prognostic model of BC based on LNM-related genes, proffering evaluation for prognosis and precise cure of BC.SIGNIFICANCE: At present, the genes related to lymph node metastasis in BC are still largely unknown and need to be further explored. Searching for potential lymph node metastasis-related genes of BC will provide meaningful biomarkers for BC treatment. Based on TCGA-BRCA data, we established an effective 11-gene prognostic risk model that could predict patient outcomes independently. Our model could classify BC patients and distinguish patients with poor prognosis effectively. Besides, the f...
Source: Journal of Proteomics - November 8, 2023 Category: Biochemistry Authors: Yinhua Pan Quanqing Zou Wu Yin Zhen Huang Yingzhu Zhao Zongming Mo Lihui Li Jianrong Yang Source Type: research
Development of lymph node metastasis-related prognostic markers in breast cancer
CONCLUSIONS: We built a prognostic model of BC based on LNM-related genes, proffering evaluation for prognosis and precise cure of BC.SIGNIFICANCE: At present, the genes related to lymph node metastasis in BC are still largely unknown and need to be further explored. Searching for potential lymph node metastasis-related genes of BC will provide meaningful biomarkers for BC treatment. Based on TCGA-BRCA data, we established an effective 11-gene prognostic risk model that could predict patient outcomes independently. Our model could classify BC patients and distinguish patients with poor prognosis effectively. Besides, the f...
Source: Journal of Proteomics - November 8, 2023 Category: Biochemistry Authors: Yinhua Pan Quanqing Zou Wu Yin Zhen Huang Yingzhu Zhao Zongming Mo Lihui Li Jianrong Yang Source Type: research
Development of lymph node metastasis-related prognostic markers in breast cancer
CONCLUSIONS: We built a prognostic model of BC based on LNM-related genes, proffering evaluation for prognosis and precise cure of BC.SIGNIFICANCE: At present, the genes related to lymph node metastasis in BC are still largely unknown and need to be further explored. Searching for potential lymph node metastasis-related genes of BC will provide meaningful biomarkers for BC treatment. Based on TCGA-BRCA data, we established an effective 11-gene prognostic risk model that could predict patient outcomes independently. Our model could classify BC patients and distinguish patients with poor prognosis effectively. Besides, the f...
Source: Journal of Proteomics - November 8, 2023 Category: Biochemistry Authors: Yinhua Pan Quanqing Zou Wu Yin Zhen Huang Yingzhu Zhao Zongming Mo Lihui Li Jianrong Yang Source Type: research
Development of lymph node metastasis-related prognostic markers in breast cancer
CONCLUSIONS: We built a prognostic model of BC based on LNM-related genes, proffering evaluation for prognosis and precise cure of BC.SIGNIFICANCE: At present, the genes related to lymph node metastasis in BC are still largely unknown and need to be further explored. Searching for potential lymph node metastasis-related genes of BC will provide meaningful biomarkers for BC treatment. Based on TCGA-BRCA data, we established an effective 11-gene prognostic risk model that could predict patient outcomes independently. Our model could classify BC patients and distinguish patients with poor prognosis effectively. Besides, the f...
Source: Journal of Proteomics - November 8, 2023 Category: Biochemistry Authors: Yinhua Pan Quanqing Zou Wu Yin Zhen Huang Yingzhu Zhao Zongming Mo Lihui Li Jianrong Yang Source Type: research
Development of lymph node metastasis-related prognostic markers in breast cancer
CONCLUSIONS: We built a prognostic model of BC based on LNM-related genes, proffering evaluation for prognosis and precise cure of BC.SIGNIFICANCE: At present, the genes related to lymph node metastasis in BC are still largely unknown and need to be further explored. Searching for potential lymph node metastasis-related genes of BC will provide meaningful biomarkers for BC treatment. Based on TCGA-BRCA data, we established an effective 11-gene prognostic risk model that could predict patient outcomes independently. Our model could classify BC patients and distinguish patients with poor prognosis effectively. Besides, the f...
Source: Journal of Proteomics - November 8, 2023 Category: Biochemistry Authors: Yinhua Pan Quanqing Zou Wu Yin Zhen Huang Yingzhu Zhao Zongming Mo Lihui Li Jianrong Yang Source Type: research
Development of lymph node metastasis-related prognostic markers in breast cancer
CONCLUSIONS: We built a prognostic model of BC based on LNM-related genes, proffering evaluation for prognosis and precise cure of BC.SIGNIFICANCE: At present, the genes related to lymph node metastasis in BC are still largely unknown and need to be further explored. Searching for potential lymph node metastasis-related genes of BC will provide meaningful biomarkers for BC treatment. Based on TCGA-BRCA data, we established an effective 11-gene prognostic risk model that could predict patient outcomes independently. Our model could classify BC patients and distinguish patients with poor prognosis effectively. Besides, the f...
Source: Journal of Proteomics - November 8, 2023 Category: Biochemistry Authors: Yinhua Pan Quanqing Zou Wu Yin Zhen Huang Yingzhu Zhao Zongming Mo Lihui Li Jianrong Yang Source Type: research
Development of lymph node metastasis-related prognostic markers in breast cancer
CONCLUSIONS: We built a prognostic model of BC based on LNM-related genes, proffering evaluation for prognosis and precise cure of BC.SIGNIFICANCE: At present, the genes related to lymph node metastasis in BC are still largely unknown and need to be further explored. Searching for potential lymph node metastasis-related genes of BC will provide meaningful biomarkers for BC treatment. Based on TCGA-BRCA data, we established an effective 11-gene prognostic risk model that could predict patient outcomes independently. Our model could classify BC patients and distinguish patients with poor prognosis effectively. Besides, the f...
Source: Journal of Proteomics - November 8, 2023 Category: Biochemistry Authors: Yinhua Pan Quanqing Zou Wu Yin Zhen Huang Yingzhu Zhao Zongming Mo Lihui Li Jianrong Yang Source Type: research
Development of lymph node metastasis-related prognostic markers in breast cancer
CONCLUSIONS: We built a prognostic model of BC based on LNM-related genes, proffering evaluation for prognosis and precise cure of BC.SIGNIFICANCE: At present, the genes related to lymph node metastasis in BC are still largely unknown and need to be further explored. Searching for potential lymph node metastasis-related genes of BC will provide meaningful biomarkers for BC treatment. Based on TCGA-BRCA data, we established an effective 11-gene prognostic risk model that could predict patient outcomes independently. Our model could classify BC patients and distinguish patients with poor prognosis effectively. Besides, the f...
Source: Journal of Proteomics - November 8, 2023 Category: Biochemistry Authors: Yinhua Pan Quanqing Zou Wu Yin Zhen Huang Yingzhu Zhao Zongming Mo Lihui Li Jianrong Yang Source Type: research
Protein biomarkers for root length and root dry mass on chromosomes 4A and 7A in wheat
This study used label-free quantitative proteomics to identify proteins associated with RL and RM in wheat near-isogenic lines (NILs). NIL pair 6 had 113 and NIL pair 9 had 30 differentially abundant proteins (DAPs). Three of identified DAPs located within the targeted genomic regions (GRs) of NIL pairs 6 (qDT.4A.1) and 9 (QHtscc.ksu-7A), showed consistent gene expressions at the protein and mRNA transcription (qRT-PCR) levels for asparagine synthetase (TraesCS4A02G109900), signal recognition particle 19 kDa protein (TraesCS7A02G333600) and 3,4-dihydroxy-2-butanone 4-phosphate synthase (TraesCS7A02G415600). This study disc...
Source: Journal of Proteomics - November 6, 2023 Category: Biochemistry Authors: Tanushree Halder Elke Stroeher Hui Liu Yinglong Chen Guijun Yan Kadambot H M Siddique Source Type: research
Protein biomarkers for root length and root dry mass on chromosomes 4A and 7A in wheat
This study used label-free quantitative proteomics to identify proteins associated with RL and RM in wheat near-isogenic lines (NILs). NIL pair 6 had 113 and NIL pair 9 had 30 differentially abundant proteins (DAPs). Three of identified DAPs located within the targeted genomic regions (GRs) of NIL pairs 6 (qDT.4A.1) and 9 (QHtscc.ksu-7A), showed consistent gene expressions at the protein and mRNA transcription (qRT-PCR) levels for asparagine synthetase (TraesCS4A02G109900), signal recognition particle 19 kDa protein (TraesCS7A02G333600) and 3,4-dihydroxy-2-butanone 4-phosphate synthase (TraesCS7A02G415600). This study disc...
Source: Journal of Proteomics - November 6, 2023 Category: Biochemistry Authors: Tanushree Halder Elke Stroeher Hui Liu Yinglong Chen Guijun Yan Kadambot H M Siddique Source Type: research
Sequential transcriptomic alterations in the cerebral cortex of mice after cerebral venous sinus thrombosis
J Proteomics. 2023 Oct 31:105035. doi: 10.1016/j.jprot.2023.105035. Online ahead of print.ABSTRACTTo investigate the expression alterations of specific genes that occur after venous stroke, we identified differentially expressed genes (DEGs) between sham and damaged cortical tissues at 2 and 7 days after induction of cerebral venous sinus thrombosis (CVST) model. The profiles of DEGs were analyzed using GO, KEGG, GSEA, and PPI, and the crucial gene was further verified by western blot and immunofluorescence. We found 969 and 883 DEGs at 2 and 7 days after CVST, respectively. A marked increase in biological-process categori...
Source: Journal of Proteomics - November 2, 2023 Category: Biochemistry Authors: Rui Ding Jing Cheng Shanshan Wei Xiaohong Qin Yaqi Liu Haiyan Li Teng Xie Huihui Chai Zhibiao Chen Source Type: research
Sequential transcriptomic alterations in the cerebral cortex of mice after cerebral venous sinus thrombosis
J Proteomics. 2023 Oct 31:105035. doi: 10.1016/j.jprot.2023.105035. Online ahead of print.ABSTRACTTo investigate the expression alterations of specific genes that occur after venous stroke, we identified differentially expressed genes (DEGs) between sham and damaged cortical tissues at 2 and 7 days after induction of cerebral venous sinus thrombosis (CVST) model. The profiles of DEGs were analyzed using GO, KEGG, GSEA, and PPI, and the crucial gene was further verified by western blot and immunofluorescence. We found 969 and 883 DEGs at 2 and 7 days after CVST, respectively. A marked increase in biological-process categori...
Source: Journal of Proteomics - November 2, 2023 Category: Biochemistry Authors: Rui Ding Jing Cheng Shanshan Wei Xiaohong Qin Yaqi Liu Haiyan Li Teng Xie Huihui Chai Zhibiao Chen Source Type: research
Sequential transcriptomic alterations in the cerebral cortex of mice after cerebral venous sinus thrombosis
J Proteomics. 2023 Oct 31:105035. doi: 10.1016/j.jprot.2023.105035. Online ahead of print.ABSTRACTTo investigate the expression alterations of specific genes that occur after venous stroke, we identified differentially expressed genes (DEGs) between sham and damaged cortical tissues at 2 and 7 days after induction of cerebral venous sinus thrombosis (CVST) model. The profiles of DEGs were analyzed using GO, KEGG, GSEA, and PPI, and the crucial gene was further verified by western blot and immunofluorescence. We found 969 and 883 DEGs at 2 and 7 days after CVST, respectively. A marked increase in biological-process categori...
Source: Journal of Proteomics - November 2, 2023 Category: Biochemistry Authors: Rui Ding Jing Cheng Shanshan Wei Xiaohong Qin Yaqi Liu Haiyan Li Teng Xie Huihui Chai Zhibiao Chen Source Type: research
Sequential transcriptomic alterations in the cerebral cortex of mice after cerebral venous sinus thrombosis
J Proteomics. 2023 Oct 31:105035. doi: 10.1016/j.jprot.2023.105035. Online ahead of print.ABSTRACTTo investigate the expression alterations of specific genes that occur after venous stroke, we identified differentially expressed genes (DEGs) between sham and damaged cortical tissues at 2 and 7 days after induction of cerebral venous sinus thrombosis (CVST) model. The profiles of DEGs were analyzed using GO, KEGG, GSEA, and PPI, and the crucial gene was further verified by western blot and immunofluorescence. We found 969 and 883 DEGs at 2 and 7 days after CVST, respectively. A marked increase in biological-process categori...
Source: Journal of Proteomics - November 2, 2023 Category: Biochemistry Authors: Rui Ding Jing Cheng Shanshan Wei Xiaohong Qin Yaqi Liu Haiyan Li Teng Xie Huihui Chai Zhibiao Chen Source Type: research
