Porto-Sinusoidal Vascular Disease: A Pediatric Study of 30 Patients
Conclusions: PSVD is responsible for nonspecific symptomatology with variable evolution sometimes marked by serious complications requiring invasive treatments or even liver transplantation. Regular monitoring is essential to prevent, detect, and treat complications. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Outcomes Analyses of Pediatric Acute Liver Failure Subjects Listed for Liver Transplantation
Background: We characterized recent outcomes in US pediatric acute liver failure (PALF) subjects listed for liver transplantation (LT) using the Scientific Registry of Transplant Recipients (SRTR) database. Methods: Pediatric subjects listed for LT from 2002 to 2015 were assigned to the “PALF” group based on status 1/1A listing, INR>2, no hepatic artery thrombosis, and no primary graft nonfunction (N = 397). Subjects were assigned to the “non-PALF” group if listed with any status other than 1/1A (N = 4509). Results: The PALF group had more infants (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Expression of IL-37 Correlates With Immune Cell Infiltrate and Fibrosis in Pediatric Autoimmune Liver Diseases
Conclusions: Pediatric ASC separates from PSC and AIH by a granulocyte-rich portal infiltrate. Upregulation of IL-37 with liver injury, the expression in Treg as well as KC and HSC and the colocalization of IL-37 with pSmad3L in cholangiocytes and hepatocytes suggest a modulating role to limit hepatic inflammation and fibrosis in pediatric autoimmune liver diseases. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Comparison of the Lipidomic Signature of Fatty Liver in Children and Adults: A Cross-Sectional Study
Conclusion: These findings suggest that, whilst similar pathways of lipid metabolism are perturbed in paediatric NAFLD as in cardiometabolic disease in adults, the specific lipid signature in children is different. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Beneficial Role of Microbial Transglutaminase in the Pathogenetic Mechanisms of Coeliac Disease
Coeliac disease (CD) is caused by immunological intolerance to wheat gluten and related proteins of rye and barley. Consequently, gluten-free (GF) products have been developed but technological implementation is required to improve their intrinsic rheological properties. One alternative for increasing the functional properties of GF foodstuff is the incorporation of microbial transglutaminase (mTG), which allows for the cross-linking of proteins that can substitute for the gluten network in the bakery industry. mTG has been, however, suggested to mimic tissue transglutaminase and to be immunogenic in CD patients. Recently,...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Review Article Source Type: research

Lessons Learned From the Long-Term Use of Enzyme Replacement Therapy in the Treatment of Lysosomal Acid Lipase Deficiency
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Invited Commentary Source Type: research

Journal of Pediatric Gastroenterology and Nutrition—The Highlights of 2021
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Editorial Source Type: research

Response to: Comment on the “NASPGHAN Position Paper on the Diagnosis and Management of Pediatric Acute Liver Failure”
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 1, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Comment on the “NASPGHAN Position Paper on the Diagnosis and Management of Pediatric Acute Liver Failure”
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 1, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Pediatric Patients With a Dual Diagnosis of Inflammatory Bowel Disease and Chronic Recurrent Multifocal Osteomyelitis: A Single-Centre Case Series - Response to Letter to the Editor
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 1, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Missing Information Regarding Chronic Recurrent Multifocal Osteomyelitis and Inflammatory Bowel Disease
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 1, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Adolescents With Inflammatory Bowel Disease Have Decreased Rates of Health Maintenance Visits
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 1, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Improving Adherence to Preventive Care Among Adolescents With Inflammatory Bowel Disease
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 1, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

A Partial Esophageal Duplication in a Two-Year-Old Female—An Incidental Finding
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 1, 2022 Category: Gastroenterology Tags: Image of the Month Source Type: research

Eosinophilic Gastritis With Linear Arrays of Pseudopolyps in the Antrum Treated With Exclusive Enteral Nutrition
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 1, 2022 Category: Gastroenterology Tags: Image of the Month Source Type: research