Journal of Pediatric Gastroenterology and Nutrition 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Randomized, Double-Blind, Placebo-Controlled Study to Assess the Effect of Two Probiotics on the Preterms’ Gut Microbiota
Conclusion:
Probiotic supplementation with L salivarius PS11603 and B longum subsp. infantis PS10402 enhanced an earlier colonization of Lactobacillus and Bifidobacterium in preterm infants’ guts in 5 and 1 week, respectively. A higher number of infants were colonized by Lactobacilli with the probiotics’ intake at the end of the study. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Clinical Trial: Nutrition Source Type: research
Endoluminal Functional Lumen Imaging Probe Is Safe in Children Under Five Years Old
Background:
Endoluminal functional lumen imaging probe (EndoFLIP) is a minimally invasive, novel device that uses high-resolution impedance planimetry to measure important parameters of the gastrointestinal lumen that aid in the diagnosis of esophageal disorders. EndoFLiP is approved by the US Food and Drug Administration (FDA) for children 5 years and older. We sought to compare its safety and luminal characteristics between children under 5 years of age with children 5 years and older.
Methods:
A single-center retrospective review was performed to identify all patients (Source: Journal of Pediatric Gastr...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Endoscopy and Procedures Source Type: research
Laparo-Endoscopic Rendez-Vous in the Treatment of Cholecysto-Choledocolithiasis in the Pediatric Population
Conclusion:
To our knowledge, this is the first consistent series of “rendez-vous technique” in the pediatric population, proving its feasibility and safety. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Endoscopy and Procedures Source Type: research
Utilization and Effectiveness of eHealth Technology in the Follow-up of Celiac Disease: A Systematic Review
Conclusions:
Although eHealth has the potential to improve the management of CD, so far, the research in the field is scarce and generally of low-moderate methodological quality. Hence, the effectiveness of eHealth in CD management remains uncertain, and more high-quality evidence is required before its utility is known. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research
Spanish National Registry of Paediatric Coeliac Disease: Changes in the Clinical Presentation in the 21st Century
Conclusions:
Paediatric CD in Spain is evolving in the same direction as in the rest of Europe, although classical CD remains the most common presentation form, and the age at diagnosis remains relatively low. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research
The Impact of Compliance During Exclusive Enteral Nutrition on Faecal Calprotectin in Children With Crohn Disease
It remains unclear whether suboptimal response to exclusive enteral nutrition (EEN) in some children with Crohn disease (CD) is explained by poor compliance. The present study measured faecal gluten immunogenic peptides (GIP), a biomarker of gluten intake, in 45 children (3– 17 years) with CD, and explored associations with faecal calprotectin (FC) levels at 33 and 54 days of EEN. FC decreased in patients with undetectable GIP at both 33 and 54 days of EEN (mean decrease, 33 days: −743 mg/kg, 54 days: –1043 mg/kg, P (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Short Communication: Gastroenterology: Inflammatory Bowel Disease Source Type: research
Risk of Post-Resection Recurrence in Pediatric Crohn Disease
In this study, we sought to determine ER rates and the impact of therapy duration before surgery in pediatric patients with CD.
Methods:
This was a single-center retrospective review of patients with CD between the ages of 2 to 20 years who required ileocecectomy between January 2015 and December 2019 at Nationwide Children's Hospital. Follow-up endoscopies, laboratory values, medications, and sPCDAI scores were recorded at 6, 12, 24, and 36 months post-resection wherever available. Modified Rutgeert scores (mRS) were independently assigned to post-resection colonoscopy images by 3 trained investigators. Post-re...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Inflammatory Bowel Disease Source Type: research
A Healthcare Physician Can Be Trained to Perform Intestinal Ultrasound in Children With Inflammatory Bowel Disease
Conclusions:
A healthcare- physician can be trained to perform IUS in children with IBD with comparable diagnostic accuracy as experienced radiologists. The interobserver agreement is moderate. Our findings support the usage of IUS in clinical management of children with IBD. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Inflammatory Bowel Disease Source Type: research
Perianal Crohn Disease Is More Common in Children and Is Associated With Complicated Disease Course Despite Higher Utilization of Biologics: A Population-based Study From The epidemiology group of the Israeli IBD Research Nucleus (epiIIRN)
Background and Objectives:
Both perianal and pediatric-onset Crohn disease (CD) disease are associated with complicated disease course and higher drug utilization. we aimed to explore the differences between pediatric and adult-onset perianal CD and their disease course.
Methods:
We included all patients with newly diagnosed CD from 2005 to 2019 at two Israeli Health Maintenance Organizations, covering 78% of the population. A combination of ICD-9 codes, radiology and procedures was used to define fistulizing perianal CD (PCD) and its severity according to the association with simple and complex perianal disease...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Inflammatory Bowel Disease Source Type: research
Long-Term Functional Outcomes of an Anorectal Malformation French National Cohort
Objectives:
The present study aimed to assess long-term functional outcomes of children with anorectal malformations (ARMs) across a network of expert centers in France.
Methods:
Retrospective cross-sectional study of patients ages 6–30 years that had been surgically treated for ARM. Patient and ARM characteristics (eg, level, surgical approach) and functional outcomes were assessed in the different age groups.
Results:
Among 367 patients, there were 155 females (42.2%) and 212 males (57.8%), 188 (51.2%) cases with, and 179 (48.8%) higher forms without, perineal fistula. Univariate and multivariate st...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research
Mechanical Complications in Central Lines Using Taurolidine Versus Ethanol Lock Therapy in Children With Intestinal Failure
Objectives:
Ethanol lock therapy (ELT) is effective in reducing rates of catheter-related-bloodstream infections (CRBSI) in the pediatric intestinal failure (IF) population; however, ELT may increase the risk of line occlusion and breakage, significantly impacting preservation of vascular access. During a period of ethanol shortage, Health Canada temporarily approved the use of taurolidine lock therapy (TLT) in pediatric iF patients previously utilizing ELT. This provided a unique opportunity to directly compare rates of central venous catheter (CVC) complications, including CRBSi, breaks, occlusions, repairs and repla...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research
Neonatal Antibiotics and Food Allergy Are Associated With FGIDs at 4–6 Years of Age
Conclusion:
Antibiotics during the first week of life resulted in a higher risk for functional abdominal pain at 4–6 years. Furthermore, food allergy was associated with IBS and abdominal migraine at 4–6years. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research
Use of Cluster Analysis to Identify Subtypes of Pediatric Functional Nausea
Objective:
The aim of the study was to evaluate whether there are clinical subtypes in children with functional nausea based on comorbidities and responses to the Nausea Profile questionnaire.
Methods:
Patients from the Neurointestinal and Motility Program clinical registry at Lurie Children's Hospital were included if they met Rome IV criteria for functional nausea. Patients completed the Nausea Profile, a multidimensional measure of nausea with gastrointestinal, emotional, and somatic subscales. Comorbidities were assessed by chart review and self-report measures. Latent class analysis was used to identify pat...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research
Evolution of International Pediatric Endoscopic Practice Changes During the Coronavirus Disease 2019 Pandemic
Objectives:
The coronavirus disease 2019 (COVID-19) pandemic has drastically altered endoscopic practices. We initially reported the international impact of COVID-19 on pediatric endoscopic practice. This follow-up study aimed to assess changes 7 months following the initial survey to delineate practice change patterns as the pandemic evolved.
Methods:
Pediatric gastroenterologists who responded to the initial survey were re-surveyed seven months later using Research Electronic Data Capture (REDCap). The survey recorded information on changes in pediatric endoscopic practice patterns, including COVID-19 screen...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research
Long-Term Sebelipase Alfa Treatment in Children and Adults With Lysosomal Acid Lipase Deficiency
Conclusion:
Sebelipase alfa was well tolerated and resulted in sustained improvements in liver and lipid parameters. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research
