Colombian School Children With Functional Gastrointestinal Disorders Respond Differently to Family Stress Than Healthy Children
Our objective is to compare coping methods, stress responses, and resilience in children with and without functional gastrointestinal disorders (FGIDs) in response to common sources of stress. We performed a case-control study. Children meeting criteria for FGIDs and matched controls completed measures of response to stress (Peer Stress, Family Stress, Academic Problems, and Recurrent Abdominal Pain versions of the Response to Stress Questionnaire) and resilience (Connor-Davidson Resilience Scale 10). We included 134 children with an FGID (57 with functional constipation and 74 with an abdominal pain-predominant FGID) and ...
Source: Journal of Pediatric Gastroenterology and Nutrition - March 26, 2019 Category: Gastroenterology Tags: Short Communication: Gastroenterology Source Type: research

Association Between Obesity/Overweight and Functional Gastrointestinal Disorders in Children
Objective: Although emerging data indicate that obese/overweight children are more likely to develop functional gastrointestinal disorders (FGIDs) than normal-weight peers, contrasting results have been reported. The present observational, case-control study aimed at estimating the prevalence of FGIDs in obese/overweight children compared to normal-weight peers. Methods: Consecutive obese and overweight children aged 4 to 18 years attending the obesity outpatient clinic were enrolled as study cases. Normal-weight children were enrolled as comparison group. All the enrolled patients received a thorough health examinati...
Source: Journal of Pediatric Gastroenterology and Nutrition - March 26, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Bacteriophage Therapy Testing Against Shigella flexneri in a Novel Human Intestinal Organoid-Derived Infection Model
Conclusions: Bacteriophages offer feasible alternatives to antibiotics for eliminating enteric pathogens, confirmed here by the bacteriophage-targeted killing of S. flexneri. Furthermore, application of the organoid model has provided important insight into Shigella pathogenesis and bacteriophage-dependent intervention strategies. The screening platform described herein provides proof-of-concept analysis for the development of novel bacteriophage therapies to target antibiotic-resistant pathogens. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - March 26, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Decreased Fecal Bacterial Diversity and Altered Microbiome in Children Colonized With Clostridium difficile
Objectives: The gut microbiome is believed to play a role in the susceptibility to and treatment of Clostridium difficile infections (CDIs). It is, however, unknown whether the gut microbiome is also affected by asymptomatic C difficile colonization. Our study aimed to evaluate the fecal microbiome of children based on C difficile colonization, and CDI risk factors, including antibiotic use and comorbid inflammatory bowel disease (IBD). Methods: Subjects with IBD and non-IBD controls were prospectively enrolled from pediatric clinics for a biobanking project (n = 113). A fecal sample was collected from each subjec...
Source: Journal of Pediatric Gastroenterology and Nutrition - March 26, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Hepatic Lesions Associated With McCune Albright Syndrome
We describe the hepatic outcome of 3 children with MAS referred to a single national liver unit. All presented with high gamma-glutamyl transpeptidase cholestasis and hepatitis. Cholestasis resolved by 1 year; but hepatic inflammation persisted, and 2 children developed progressive atypical focal nodular hyperplasia and 1 developed hepatoblastoma. This the first reported malignant hepatic lesion associated with MAS. MAS should be considered part of the differential diagnosis of neonatal cholestasis and affected children should be closely monitored for the development of hepatic lesions with regular liver ultrasound and alp...
Source: Journal of Pediatric Gastroenterology and Nutrition - March 26, 2019 Category: Gastroenterology Tags: Short Communication: Hepatology Source Type: research

A Phase I/IIa Trial of Intravenous Immunoglobulin Following Portoenterostomy in Biliary Atresia
Conclusions: Although IVIg infusions in infants with BA post-HPE were feasible, acceptable and safe, there was no trend to lower bilirubin levels or improved 360-day survival with the native liver. Clinical Trial: Safety Study of Intravenous Immunoglobulin Post-Portoenterostomy in Biliary Atresia; #NCT01854827. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - March 26, 2019 Category: Gastroenterology Tags: Clinical Trials: Hepatology Source Type: research

Biliary Atresia–associated Cholangitis: The Central Role and Effective Management of Bile Lakes
Objectives: Cholangitis and bile lakes are incompletely understood complications after portoenterostomy (PE). We investigated relationships between recurrent cholangitis, bile lakes, and clinical outcomes as well as surgical management of bile lakes. Methods: In this retrospective observational single institution study medical records and imaging studies of all patients who had undergone PE for biliary atresia during 1987 to 2016 (N = 61) were reviewed. We related occurrence of cholangitis episodes with the presence of intrahepatic bile lakes, patient characteristics, and PE outcomes. Risk factors for recurrent ch...
Source: Journal of Pediatric Gastroenterology and Nutrition - March 26, 2019 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Impact of Immunosuppression on Executive Functioning After Pediatric Liver Transplantation: An Observational Cohort Study
Conclusions: In addition to a strong impact of disease burden around transplantation, executive functioning appears to deteriorate over time. Although there is no clear-cut advantage of any CNI, once-daily Tac appears to be advantageous compared to twice-daily Tac. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - March 26, 2019 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

The Impact of Increased Allocation Priority for Children Awaiting Liver Transplant: A Liver Simulated Allocation Model (LSAM) Analysis
Objective: The aim of the study was to investigate the impact of prioritizing infants, children, adolescents, and the sickest adults (Status 1) for deceased donor livers. We compared outcomes under two “SharePeds” allocation schema, which prioritize children and Status 1 adults for national sharing and enhanced access to pediatric donors or all donors younger than 35 years, to outcomes under the allocation plan approved by the Organ Procurement and Transplant Network in December 2017 (Organ Procurement and Transplantation Network [OPTN] 12-2017). Methods: The 2017 Liver Simulated Allocation Model and Scien...
Source: Journal of Pediatric Gastroenterology and Nutrition - March 26, 2019 Category: Gastroenterology Tags: Rapid Communication: Hepatology Source Type: research

Antiemetic Drug Use in Children: What the Clinician Needs to Know
Vomiting is not only unpleasant for both children and families, but can lead to frequent hospital admission. The persistent vomiting hampers oral intake and increases the risk of dehydration, so the proper use of antiemetic drugs can be useful. The pharmacological treatment of vomiting in children remains a challenge for the pediatrician because several antiemetics are prescribed as “off-label,” outside their authorized drug label. Domperidone and ondansetron are the most commonly known antiemetic drugs. A single oral dose of ondansetron has been shown to reduce the risk of recurrent vomiting, the need for intr...
Source: Journal of Pediatric Gastroenterology and Nutrition - March 26, 2019 Category: Gastroenterology Tags: Review Article Source Type: research

Treating Biliary Atresia: The Challenge Continues
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - March 26, 2019 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

The Gut Microbiome: A Difficult Target for Translational Studies of: Clostridium difficile: Colonization
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - March 26, 2019 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

Cannabis Oil Use by Adolescents and Young Adults With Inflammatory Bowel Disease
Conclusions: Adolescent and young adults with IBD used oral CO and many used other cannabis products as well. Users perceived some medical benefit. Care teams should strive for open communication about use until further information on safety and efficacy becomes available. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - March 1, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Inflammatory Bowel Disease Source Type: research

Fecal Microbiota Transplant for Recurrent Clostridium difficile Infection in Pediatric Inflammatory Bowel Disease
Conclusions: With a cure rate of 75% at 60 days, FMT administered for the treatment of RCDI may be an effective treatment option in pediatric IBD. However, there appears to be a significant rate of late recurrence of C difficile infection after 60 days in these patients. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - March 1, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Inflammatory Bowel Disease Source Type: research

Training in Endoscopy: Coaching, Deliberate Practice, and Reflection
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - March 1, 2019 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

Biologics and Surgery in Inflammatory Bowel Disease: Learning at the Cutting Edge
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - March 1, 2019 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

International Meeting Chronic Gastrointestinal Diseases From the Child to the Adult, April 4-6, 2019
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Abstracts Source Type: research

Dehydrated Hereditary Stomatocytosis Presenting as Severe Perinatal Ascites and Cholestasis
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Case Report Source Type: research

Noncirrhotic Portal Fibrosis in a Young Girl
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Image of the Month Source Type: research

Pneumatosis Cystoides Intestinalis
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Image of the Month Source Type: research

Management of Juvenile Polyposis Syndrome in Children and Adolescents: A Position Paper From the ESPGHAN Polyposis Working Group
The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Polyposis Working Group developed recommendations to assist clinicians and health care providers with appropriate management of patients with juvenile polyposis. This is the first juvenile polyposis Position Paper published by ESPGHAN with invited experts. Many of the published studies were descriptive and/or retrospective in nature, consequently after incorporating a modified version of the GRADE system many of the recommendations are based on expert opinion. This ESPGHAN Position Paper provides a guide for diagnosis, assessment, and ...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Society Papers Source Type: research

Management of Peutz-Jeghers Syndrome in Children and Adolescents: A Position Paper From the ESPGHAN Polyposis Working Group
Peutz-Jeghers syndrome (PJS) is a well-described inherited syndrome, characterized by the development of gastrointestinal polyps, and characteristic mucocutaneous freckling. Development of small bowel intestinal polyps may lead to intussusception in children may require emergency laparotomy with potential loss of bowel. Gastrointestinal polyps may lead to bleeding and anemia. This European Society for Paediatric Gastroenterology Hepatology and Nutrition position paper provides a guide for diagnosis, assessment, and management of PJS in children and adolescents and guidance on avoiding complications from PJS or from the end...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Society Papers Source Type: research

Management of Familial Adenomatous Polyposis in Children and Adolescents: Position Paper From the ESPGHAN Polyposis Working Group
Familial adenomatous polyposis (FAP) is a well-described inherited syndrome, characterized by the development of hundreds to thousands of adenomas in the colorectum, with implications in children and adolescents. Almost all adult patients will develop colorectal cancer if they are not identified and treated early enough. Identifying and screening for FAP commences in adolescence. The syndrome is inherited as an autosomal dominant trait and caused by mutations in the adenomatous polyposis (APC) gene. This European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) position paper provides a guide for...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Society Papers Source Type: research

Resting Energy Expenditure in Patients With Familial Dysautonomia: A Preliminary Study
Conclusions: Hypermetabolic state was described in 50% of FD patients. The Low BMI is explained by combination of relative anorexia and increased REE. The REE levels are related to the underling respiratory disease. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research

Symptoms of Feeding Problems in Preterm-born Children at 6 Months to 7 Years Old
Objectives: Describe symptoms of feeding problems in children born very preterm ( (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research

Are All Breast-fed Infants Equal? Clustering Metabolomics Data to Identify Predictive Risk Clusters for Childhood Obesity
Objectives: Fetal and early life represent a period of developmental plasticity during which metabolic pathways are modified by environmental and nutritional cues. Little is known on the pathways underlying this multifactorial complex. We explored whether 6 months old breast-fed infants could be clustered into metabolically similar groups and that those metabotypes could be used to predict later obesity risk. Methods: Plasma samples were obtained from 183 breast-fed infants aged 6 months participating in the European multicenter Childhood Obesity Project study. We measured amino acids along with polar lipid concentrat...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research

Breastfeeding Rates and Programs in Europe: A Survey of 11 National Breastfeeding Committees and Representatives
Conclusions: National governments should commit to evidence-based breastfeeding monitoring and promotion activities, including financial and political support, to improve breastfeeding rates in the Europe. Renewed efforts for collaboration between countries in Europe, including a sustainable platform for information exchange, are needed. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research

Systematic Review of Probiotics for Cystic Fibrosis Patients: Moving Forward
Conclusions: The present data indicate a promising future for probiotic use in cystic fibrosis, which has an impact on exacerbations and intestinal inflammation; however, further studies of standardized therapeutic interventions are required. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Pancreatology Source Type: research

Validation of Lipase and Systemic Inflammatory Response Syndrome as Prognostic Indicators in Pediatric Acute Pancreatitis: A Retrospective Analysis
Introduction: Acute pancreatitis (AP) is understudied in the pediatric population despite increasing incidence. Although many cases are mild and resolve with supportive care, severe acute pancreatitis (SAP) can be associated with significant morbidity and mortality. There is a lack of pediatric-specific predictive tools to help stratify risk of SAP in children. Methods: A retrospective cohort study of patients with AP or recurrent AP at Cohen Children's Medical Center between 2011 and 2016 was performed. Lipase level and the presence of pediatric systemic inflammatory response syndrome (SIRS) on admission were examine...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Pancreatology Source Type: research

Recanalization of Chronic Extrahepatic Portal Vein Obstruction in Pediatric Patients Using a Minilaparotomy Approach
Conclusions: Recanalization and stenting of a prolonged occlusion of the portal vein via a minilaparotomy approach is feasible, safe, and may provide an alternative to shunt surgery or endoscopic therapy in selected patients. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Cardiovascular Risk Assessment in Pediatric Liver Transplant Patients
Objectives: Cardiovascular (CV) diseases play a leading role in the mortality of adult liver transplant (LT) recipients. However, data regarding CV risk factors in children after LT remain sparse. The present study assessed the presence of CV risk factors and signs of CV impairment in LT children. Methods: A total of 42 LT recipients (21 men, age 9.93 ± 3.57 years) were studied. Body composition [body mass index standard deviation score, percentage of body fat (by bioimpedance analysis)], lipid profiles, glycemic control, blood pressure, and arterial stiffness [assessed by aortic pulse wave velocity (PWV)] ...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

The Frequency of Lysosomal Acid Lipase Deficiency in Children With Unexplained Liver Disease
Objectives: Evidence suggests that lysosomal acid lipase deficiency (LAL-D) is often underdiagnosed because symptoms may be nonspecific. We aimed to investigate the prevalence of LAL-D in children with unexplained liver disease and to identify demographic and clinical features with a prospective, multicenter, cross-sectional study. Methods: Patients (aged 3 months–18 years) who had unexplained transaminase elevation, unexplained hepatomegaly or hepatosplenomegaly, obesity-unrelated liver steatosis, biopsy-proven cryptogenic fibrosis and cirrhosis, or liver transplantation for cryptogenic cirrhosis were enrolled....
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Prevalence of Celiac Disease in a Long-term Study of a Spanish At-genetic-risk Cohort From the General Population
Conclusions: A repeated screening of at-risk children during their follow-up allowed us to diagnose new CD cases. In our cohort, HLA- DQ2.5 trans genotype conferred a higher risk in the development of CD than HLA- DQ2.5/DQ2.2. The majority of children with potential CD and CD autoimmunity at 10 years of age remained healthy. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research

Intracellular Localization of Microbial Transglutaminase and Its Influence on the Transport of Gliadin in Enterocytes
Conclusions: mTG and gliadin are transported to the ER of enterocytes and to a greater extent to the ER of RACE cells, suggesting cross-presentation of exogenous antigens. The strong localization of mTG at the basolateral membrane and the lamina propria may also indicate a potential antigenic interaction with cells of the immune system. Since mTG may not only been taken up with food stuffs but could also be released by bacteria within the intestinal microbiota, further investigations are needed regarding the role of mTG in CD pathogenesis. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research

Effects of the Gluten-free Diet on Body Mass Indexes in Pediatric Celiac Patients
Conclusions: Although overall we observed no significant changes in BMI before and after 2011, we did notice that in adolescent celiac patients there was a trend toward a higher postdiagnosis BMI in the years after 2011. We speculate that teenagers may be especially vulnerable to choosing quick and easy processed gluten-free options over more healthy, natural alternatives leading to a rise in their BMIs after the 2011 surge in production of processed gluten-free foods on the market. Therefore, special attention must be paid to this population to insure ongoing healthy food choices even after many years on the GFD. (Sourc...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research

Quantitative Analysis of Apparent Diffusion Coefficient for Disease Assessment in Paediatric Inflammatory Bowel Disease
Conclusions: ADC can provide a scanner-based quantitative measurement of disease activity. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Inflammatory Bowel Disease Source Type: research

Cannabis Oil Use by Adolescents and Young Adults With Inflammatory Bowel Disease
Conclusions: Adolescent and young adults with IBD used oral CO and many used other cannabis products as well. Users perceived some medical benefit. Care teams should strive for open communication about use until further information on safety and efficacy becomes available. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Inflammatory Bowel Disease Source Type: research

Fecal Microbiota Transplant for Recurrent Clostridium difficile Infection in Pediatric Inflammatory Bowel Disease
Conclusions: With a cure rate of 75% at 60 days, FMT administered for the treatment of RCDI may be an effective treatment option in pediatric IBD. However, there appears to be a significant rate of late recurrence of C difficile infection after 60 days in these patients. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Inflammatory Bowel Disease Source Type: research

Shared Decision Making About Starting Anti-TNFs: A Pediatric Perspective
Shared decision making (SDM) is central to patient-centered medicine and has the potential to improve outcomes for pediatric patients with inflammatory bowel diseases. We surveyed specialists about their use of SDM in the decision to start a tumor necrosis factor-α inhibitor in pediatric patients. Results were compared between those who reported using SDM and those who did not. Of 209 respondents, 157 (75%) reported using SDM. Physician/practice characteristics were similar between users and nonusers. There were no statistically significant differences between groups in the components deemed important to the decision...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Short Communication: Gastroenterology: Inflammatory Bowel Disease Source Type: research

The Effect of Biologics on Postoperative Complications in Children With Inflammatory Bowel Disease and Bowel Resection
Conclusion: The number of complications was the same between those who did and did not receive a preoperative biologic agent. This study suggests that biologics may be safe to use in patients undergoing bowel resection. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Article: Gastroenterology: Inflammatory Bowel Disease Source Type: research

Eculizumab Is Safe and Effective as a Long-term Treatment for Protein-losing Enteropathy Due to CD55 Deficiency
Objectives: Loss of the complement inhibitor CD55 leads to a syndrome of early-onset protein-losing enteropathy (PLE), associated with intestinal lymphangiectasia and susceptibility to large-vein thrombosis. The in vitro and short-term treatment benefits of eculizumab (C5-inhibitor) therapy for CD55-deficiency have been previously demonstrated. Here we present the 18-months treatment outcomes for 3 CD55-deficiency patients with sustained therapeutic response. Methods: Three CD55-deficiency patients received off-label eculizumab treatment. Clinical and laboratory treatment outcomes included frequency and consistency of...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Article: Gastroenterology Source Type: research

PEG 3350 Versus Lactulose for Treatment of Functional Constipation in Children: Randomized Study
Conclusions: PEG 3350 is more effective and causes fewer side effects than lactulose in the treatment of constipation in infants and children. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Clinical Trials: Gastroenterology Source Type: research

Can Pediatric Endoscopists Accurately Assess Their Clinical Competency? A Comparison Across Skill Levels
Conclusions: We found that endoscopic experience was positively associated with self-assessment accuracy among pediatric endoscopists. Novices were inaccurate in assessing their endoscopic competence and were prone to overestimation of their performances. Our findings suggest novices may benefit from targeted interventions aimed at improving their insight and self-awareness. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Clinical Safety and Utility of Pediatric Balloon-assisted Enteroscopy: A Multicenter Prospective Study in Japan
Objectives: The benefit of balloon-assisted enteroscopy (BAE) had been recently documented in pediatric patients, but previous reports are based on single institution experiences. We evaluated the feasibility of pediatric BAE in 8 tertiary referral hospitals throughout Japan. Methods: This was a prospective, multi-institutional study. Patients younger than 18 years were enrolled between April 2014 and March 2017 to undergo double-balloon or single-balloon enteroscopy. Data were collected prospectively using a standardized questionnaire. Results: We enrolled 79 pediatric patients (96 procedures, 70 boys, 26 girls; m...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Conceptual Model of Lean Body Mass in Pediatric Inflammatory Bowel Disease
Youth with inflammatory bowel disease (IBD) demonstrate deficits in lean mass (LM) placing them at increased risk for future health problems, including reduction of bone mass and impaired bone architecture. Research suggests that deficits in LM are multifactorial, including influences from the disease and its treatment, and health behaviors such as diet and physical activity. Based on a systematic literature review examining factors related to LM deficits in IBD, this article presents a conceptual model to explain the development of LM in youth with IBD. The model considers predictors of LM across 4 domains: demographic; m...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Review Article Source Type: research

Training in Endoscopy: Coaching, Deliberate Practice, and Reflection
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

Biologics and Surgery in Inflammatory Bowel Disease: Learning at the Cutting Edge
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

Promoting and Protecting Breast-feeding: The Importance of Good Quality Data
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

Master Educator Award 2018: B U.K. Li, MD
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Special Features Source Type: research

2018 AAP Murray Davidson Award: David Piccoli
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - February 26, 2019 Category: Gastroenterology Tags: Special Features Source Type: research