Clinical Presentation of Acute Gastroenteritis in Children With Functional Abdominal Pain Disorders
ABSTRACT: Visceral hypersensitivity and abnormal coping are common in children with functional abdominal pain disorders (FAPDs). Thus, it would be expected that children with visceral hypersensitivity would report more pain if their gut is acutely inflamed. The aim of the study was to compare clinical symptoms and somatization of children with and without FAPDs at time of an episode of acute gastroenteritis. Seventy children with acute gastroenteritis and their parents completed the Rome III Diagnostic Questionnaire for Pediatric Functional GI Disorders and the Children's Somatization Inventory. Twenty-one percent of child...
Source: Journal of Pediatric Gastroenterology and Nutrition - July 26, 2017 Category: Gastroenterology Tags: Short Communication: Gastroenterology Source Type: research

Validation of a Simple Stool Diary Used by Caregivers to Document Diarrhea Among Young Children in a Low-Income Country
Objectives: The aim of the study was the development and validation of a simple stool diary for caretakers collecting data on stool frequency and consistency among young children in a low-income country. Methods: Focus group studies evaluated how diarrhea was understood by caregivers (content validity). The sensitivity, reliability, and correlations between dehydration and diary scores (construct validity) were tested in a clinical trial. Results: Caregivers recognized and understood the concept and severity of diarrhea. Stool frequency and liquid consistency decreased in children admitted with diarrhea (P  (Source: Jo...
Source: Journal of Pediatric Gastroenterology and Nutrition - July 26, 2017 Category: Gastroenterology Tags: Original Article: Gastroenterology Source Type: research

Elevated Hemoglobin Level Is Associated With Advanced Fibrosis in Pediatric Nonalcoholic Fatty Liver Disease
Objectives: Hemoglobin (Hb) and red blood cell distribution width (RDW) have been reported to be a risk marker of metabolic syndrome and nonalcoholic fatty liver disease (NAFLD). No study exists on pediatric populations. We aimed to determine the association between hematological parameters, and the severity of disease in children with biopsy-proven NAFLD. Methods: A total of 117 children (85 boys, mean age 12 years) with ultrasound evidence of NAFLD undergoing liver biopsy for diagnosis of nonalcoholic steatohepatitis (NASH), were prospectively enrolled between January 2011 and May 2013 in the setting of a tertiary care ...
Source: Journal of Pediatric Gastroenterology and Nutrition - July 26, 2017 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Systematic Review: Nutrition and Physical Activity in the Management of Paediatric Nonalcoholic Fatty Liver Disease
Conclusions: The limited evidence base inhibits the prescription of specific dietary and/or lifestyle strategies for clinical practice. General healthy eating and physical activity guidelines, promoting weight loss, should remain first-line treatment until high-quality evidence emerges that support specific interventions that offer additional clinical benefit. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 26, 2017 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Ultrasound-guided Liver Biopsies in Children: A Single-center Experience and Risk Factors for Minor Bleeding
Objectives: The aim of the study was to analyze the institution's experience in ultrasound-guided liver biopsies performed on children and identify risk factors for complications, following a previous study performed in our institution. Methods: Retrospective analysis of a consecutive series of ultrasound-guided pediatric liver biopsies, between 2011 and 2016. Demographic and anthropometric data, biopsy indications, international normalized ratio (INR) and platelet count, biopsy technique, complications, and pathologic outcomes were recorded. Results: A total of 228 procedures were performed on 203 children with a median...
Source: Journal of Pediatric Gastroenterology and Nutrition - July 26, 2017 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Path of Interchangeability of Biosimilars in Pediatric Inflammatory Bowel Disease: Quality Before Cost Savings
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 26, 2017 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

A Public Health and Data Crisis You Can Help Solve: CPSC's Critical Need for NASPGHAN's Data
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 26, 2017 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

Microbiota, Environment, and Diet
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Apropos: “Gut Microbiota Differences in Children From Distinct Socioeconomic Levels Living in the Same Urban Area in Brazil”
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Liver Failure in Early Infancy
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Characterizing and Defining “Infantile Liver Failure”
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

An Unusual Manifestation of Celiac Disease in an Adolescent With Down Syndrome and Graves Disease
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Case Reports Source Type: research

Allergic Interstitial Nephritis Masquerading as Pyelonephritis in a Pediatric Patient With Crohn Disease
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Case Reports Source Type: research

Endoscopic Drainage of Walled Off Necrosis in a Child With Metal Stent
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Video of the Month Source Type: research

Giant Pelvic Cyst in 16-Year-Old Boy With Bloody Diarrhea: Atypical Presentation of Colonic Adenocarcinoma
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Image of the Month Source Type: research

Quality Improvement in Pediatric Endoscopy: A Clinical Report From the NASPGHAN Endoscopy Committee
This report is intended to provide pediatric gastroenterologists with a framework for the development and implementation of endoscopy QI programs within their own centers, based on available evidence and expert opinion from the members of the NASPGHAN Endoscopy Committee. This clinical report will require expansion as further research pertaining to endoscopic quality in pediatrics is published. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Clinical Report Source Type: research

Commercial Probiotic Products: A Call for Improved Quality Control. A Position Paper by the ESPGHAN Working Group for Probiotics and Prebiotics
ABSTRACT: Probiotics have been proposed for a number of indications ranging from the hypothetical long-term immunomodulatory effects to proven benefits in the management of different clinical conditions. An increasing number of commercial products containing probiotics are available. In those products, irrespective if it is food, food supplement, medical food, or drug, the probiotic microorganisms have to be present in a sufficient number by the end of the shelf-life, to pass through the gastrointestinal tract resisting acid and bile, to colonize the gut, and to retain functional properties required to obtain the suggeste...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Society Papers Source Type: research

Nutritional Practices and Growth in Premature Infants After Surgical Necrotizing Enterocolitis
Conclusions: Postoperative protein doses in infants with surgical NEC appear related to increases in HC. The influence of postoperative nutritional support on risk of adverse outcomes deserves further attention. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Article: Nutrition Source Type: research

Early Empiric Antibiotic Use Is Associated With Delayed Feeding Tolerance in Preterm Infants: A Retrospective Analysis
The objective of this study was to evaluate whether early empiric antibiotic exposure negatively affects preterm infants’ enteral feeding tolerance. Data from infants without risk factors for sepsis, 500 to 1499 g birth weight and 24 to 34 weeks gestational age were analyzed. The primary outcomes were the empiric antibiotic exposure effects on the infants’ total parenteral nutrition usage duration and prevalence of necrotizing enterocolitis (NEC). Among the 901 infants included, 67 were exposed to early empiric antibiotic. A 50% increase in parenteral nutrition usage duration and a 4-fold greater prevalence of ...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Short Communications: Nutrition Source Type: research

Effect of Synbiotic on the Gut Microbiota of Cesarean Delivered Infants: A Randomized, Double-blind, Multicenter Study
ABSTRACT: We determined the effect of short-chain galacto-oligosaccharides (scGOS), long-chain fructo-oligosaccharides (lcFOS) and Bifidobacterium breve M-16V on the gut microbiota of cesarean-born infants. Infants were randomized to receive a standard formula (control), the same with scGOS/lcFOS and B. breve M-16V (synbiotic), or with scGOS/lcFOS (prebiotic) from birth until week 16, 30 subjects born vaginally were included as a reference group. Synbiotic supplementation resulted in a higher bifidobacteria proportion from day 3/5 (P  (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Short Communications: Nutrition Source Type: research

Increased Fat Absorption From Enteral Formula Through an In-line Digestive Cartridge in Patients With Cystic Fibrosis
Conclusions: Use of this in-line digestive cartridge was safe and well tolerated, and resulted in significantly increased levels of plasma omega-3 FA used with enteral formula, suggesting an overall increased fat absorption. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Rapid Communication: Pancreatology Source Type: research

Primary Budd-Chiari Syndrome in Children: King's College Hospital Experience
ABSTRACT: Primary Budd-Chiari syndrome is a rare cause of liver disease in children in the western world. Here we present a retrospective review of children with Primary Budd-Chiari syndrome presenting from January 2001 to November 2015 to our hospital. Seven children were identified. Their presentation was mostly chronic. All had predisposing factors for thrombosis and were started on anticoagulation. Radiological interventions (2 transjugular intrahepatic portosystemic shunts and 1 hepatic vein stenting), liver transplant and mesocaval shunt were done in 3, 2, and 1 patients, respectively; 1 child underwent bone marrow t...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Short Communication: Hepatology Source Type: research

Low Hepatic Tissue Copper in Pediatric Nonalcoholic Fatty Liver Disease
Objective: Animal models and studies in adults have demonstrated that copper restriction increases severity of liver injury in nonalcoholic fatty liver disease (NAFLD). This has not been studied in children. We aimed to determine if lower tissue copper is associated with increased NAFLD severity in children. Methods: This was a retrospective study of pediatric patients who had a liver biopsy including a hepatic copper quantitation. The primary outcome compared hepatic copper concentration in NAFLD versus non-NAFLD. Secondary outcomes compared hepatic copper levels against steatosis, fibrosis, lobular inflammation, balloon...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Article: Hepatology Source Type: research

Outpatient Liver Biopsy in Children: Safety, Feasibility, and Economic Impact
ABSTRACT: Liver biopsy is a valuable tool. Even though outpatient liver biopsies are routinely performed in adults, there are no clear recommendations on its safety and feasibility in children. We reviewed the records of children who underwent a percutaneous liver biopsy at our institution between January 2005 and June 2015. A total of 626 biopsies were performed on 497 patients (250 boys, median age 6 [0.2–19.3] years). Abnormal liver function tests for investigation 288 (46%) was the most common indication. Thirty (4.8%) biopsies had complications, most common being subcapsular hematoma 14 of 30 (46.7%). Complicati...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Short Communication: Hepatology Source Type: research

Outcomes in Pediatric Autoimmune Hepatitis and Significance of Azathioprine Metabolites
Conclusions: The vast majority of children with AIH maintain a sustained remission with AZA monotherapy. Biochemical remission was maintained with 6-TGN levels much lower than that recommended for inflammatory bowel disease. These findings suggest that patients should be maintained at the lowest AZA dose possible that is associated with biochemical remission. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Article: Hepatology Source Type: research

Development and Function of Immune Cells in an Adolescent Patient With a Deficiency in the Interleukin-10 Receptor
Conclusions: With time and during immunosuppressive treatment the IL10RA-deficient immune system develops relatively normally. Upon activation, IL-10 is crucial for controlling excessive inflammatory cytokine release by dendritic cells and preventing interferon γ and IL-17-mediated T-cell responses. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Article: Gastroenterology: Inflammatory Bowel Disease Source Type: research

Extraintestinal Manifestations of Celiac Disease: Effectiveness of the Gluten-Free Diet
Conclusions: Children and adults with celiac disease have similar rates of extraintestinal manifestations. In children short stature, fatigue, and headache were most common, whereas anemia, fatigue, and headache/psychiatric disorders were most common in adults. Children on a strict GFD showed faster and higher rates of symptom resolution as compared to adults. Unresponsive children with short stature must be assessed for comorbidities. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research

Elevated Serum Tissue Transglutaminase Antibodies in Children With Eosinophilic Esophagitis
Conclusions: Serum TTG Ab was elevated in almost one-quarter of our total EoE cohort, and at least 20% of these patients did not have potential CD, suggesting EoE is a heterogeneous disease with differing immune mechanisms activated in some patients. These findings also support routine esophageal biopsy during upper endoscopy in children with elevated TTG Ab. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research

Adherence to Celiac Disease and Eosinophilic Esophagitis Biopsy Guidelines Is Poor in Children
Objectives: Celiac disease (CD) and eosinophilic esophagitis (EoE) are underdiagnosed gastrointestinal conditions, which adversely affect children's health. Previous studies have shown that diagnostic guidelines for CD are not consistently followed in adults. The aims of the present study are to assess the frequency with which endoscopists comply with diagnostic guidelines for CD and EoE in children, and to determine whether an association exists between adherence to biopsy guidelines and disease detection in pediatric patients. Methods: We reviewed pathology reports from 9171 children (ages 0–18) with at least 1 du...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research

The Association Between Celiac Disease and Eosinophilic Esophagitis: Mayo Experience and Meta-analysis of the Literature
Conclusions: Based on our cohort and the observational data, the diagnosis of CD in children is not associated with increased risk of EoE. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research

Lack of Knowledge and Low Readiness for Health Care Transition in Eosinophilic Esophagitis and Eosinophilic Gastroenteritis
Conclusions: There was a significant deficit in HCT knowledge, and HCT readiness scores were lower than other chronic health conditions. HCT preparation and readiness assessments should become a priority for adolescents/young adults with EoE/EGE and their parents. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Filaggrin and Periostin Expression Is Altered in Eosinophilic Esophagitis and Normalized With Treatment
Objectives: Previous data have suggested that filaggrin (FLG) and periostin (POSTN) genes may be dysregulated in eosinophilic esophagitis (EoE). We aimed to further evaluate the expression patterns of FLG and POSTN proteins in esophageal tissue samples of patients with EoE, as compared to those of patients with gastroesophageal reflux disease (GERD) and normal controls. Methods: A total of 61 prospectively collected cases, including 40 children with EoE and 21 children with GERD, and a control group of 14 sex- and age-matched healthy children were enrolled. Patients with EoE were treated with skin testing–driven eli...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Biomarkers of Environmental Enteric Dysfunction Among Children in Rural Bangladesh
Objectives: Environmental enteric dysfunction (EED) may inhibit growth and development in low- and middle-income countries, but available assessment methodologies limit its study. In rural Bangladesh, we measured EED using the widely used lactulose mannitol ratio (L:M) test and a panel of intestinal and systemic health biomarkers to evaluate convergence among biomarkers and describe risk factors for EED. Methods: In 539 18-month-old children finishing participation in a randomized food supplementation trial, serum, stool, and urine collected after lactulose and mannitol dosing were analyzed for biomarkers of intestinal ab...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Age and Sex Normalization of Intestinal Permeability Measures for the Improved Assessment of Enteropathy in Infancy and Early Childhood: Results From the MAL-ED Study
Conclusions: Alterations in recovery of the probes differ markedly in different epidemiologic contexts in children living in the developing world. The rate of change in the L:M-z ratio was most rapid and consistently disparate from the reference standard in the period between 6 and 9 months of age, suggesting that this is a critical period of physiologic impact of enteropathy in these populations. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Twelve Novel Mutations in the SLC26A3 Gene in 17 Sporadic Cases of Congenital Chloride Diarrhea
Conclusions: We confirm the molecular heterogeneity of sporadic CCD adding 12 novel mutations to the list of known pathogenic mutations. Moreover, we underline the importance, for laboratories that offer molecular diagnosis and genetic counseling, to perform fast functional analysis of novel mutations. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Yield of Endoscopy in Pediatric Gastroparesis
Conclusions: Clinically significant endoscopy findings were common in both controls and gastroparetics. As more than one-third of patients had findings on endoscopy, we conclude that upper endoscopy remains an important part of the evaluation process of patients with dyspeptic symptoms and suspected gastroparesis. As gross abnormalities were frequently not present with histologic changes, routine biopsy is required. There was no association between studied symptoms and the presence of gastroparesis. A comprehensive evaluation of children with dyspeptic symptoms requires endoscopy with biopsy and solid-phase gastric emptyin...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Treatment of Functional Abdominal Pain With Antidepressants: Benefits, Adverse Effects, and the Gastroenterologist's Role
Conclusions: Patients had significantly greater response to SSRIs than TCAs, remaining significant after controlling for psychiatric factors. Little significance is given to patient's associated gastrointestinal symptoms, frequently resulting in adverse effects and termination of medication. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Intestinal Metaplasia of the Esophagus in Children With Esophageal Atresia
Conclusions: IM occurs in patients with EA-TEF, some as young as 2 years. Therefore, early endoscopic surveillance should be considered in this GER-prone population. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Second-line Agents in Pediatric Patients With Autoimmune Hepatitis: A Systematic Review and Meta-analysis
Conclusions: Cyclosporine had the highest response rate at 6 months in children with standard-treatment-refractory AIH; however, it also had the highest rate of adverse events. MMF was the second most efficacious option with a low adverse effect rate. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Invited Review Source Type: research

Biomarkers of Environmental Enteric Dysfunction: The Good, the Bad, and the Ugly
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

Pediatric Autoimmune Hepatitis: What Do You Do When First-line Therapy Fails?
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

Eosinophilic Esophagitis and Celiac Disease: A True Association or Coincidence?
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 27, 2017 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

Video Capsule Endoscopy to Diagnose Primary Intestinal Lymphangiectasia in a 14-Month-Old Child
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 24, 2017 Category: Gastroenterology Tags: Letter to the Editor Source Type: research

Apoptotic Enteropathy in a Neonate With Allergic Enterocolitis
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 24, 2017 Category: Gastroenterology Tags: Case Reports Source Type: research

Clostridium difficile Ileitis in Pediatric Inflammatory Bowel Disease
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 24, 2017 Category: Gastroenterology Tags: Case Reports Source Type: research

Isolated Appendiceal Pinworms on Colonoscopy
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 24, 2017 Category: Gastroenterology Tags: Video of the Month Source Type: research

Inflammatory Fibroid Polyp of the Esophagogastric Junction
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 24, 2017 Category: Gastroenterology Tags: Image of the Month Source Type: research

Joint ESPGHAN/NASPGHAN Guidelines for the Management of Helicobacter pylori in Children and Adolescents (Update 2016)
Conclusions: The primary goal of clinical investigation is to identify the cause of upper gastrointestinal symptoms rather than H pylori infection. Therefore, we recommend against a test and treat strategy. Decreasing eradication rates with previously recommended treatments call for changes to first-line therapies and broader availability of culture or molecular-based testing to tailor treatment to the individual child. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 24, 2017 Category: Gastroenterology Tags: Society Papers Source Type: research

Classification of Acute Pancreatitis in the Pediatric Population: Clinical Report From the NASPGHAN Pancreas Committee
Discussion: Severity in pediatric AP is classified as mild, moderately severe, or severe. Mild AP is defined by AP without organ failure, local or systemic complications, and usually resolves in the first week. Moderately SAP is defined by the presence of transient organ failure that resolves in no>48 hours, or local complications or exacerbation of co-morbid disease. SAP is defined by persistent organ failure that lasts (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 24, 2017 Category: Gastroenterology Tags: Society Papers Source Type: research

Body Composition Trajectories From Infancy to Preschool in Children Born Premature Versus Full-term
Conclusions: Children born prematurely and full-term have similar body composition at preschool age. For preterms infancy fat-free mass gains, and not adiposity gains, are positively associated with preschool fat-free mass; this may be associated with lower risk of later obesity and adverse metabolic outcomes. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - May 24, 2017 Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research