Journal of Pediatric Gastroenterology and Nutrition This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Children With Cystic Fibrosis Have Elevated Levels of Fecal Chitinase-3-like-1
Although chitinase-3-like-1 (CHI3L1), predominately produced by epithelial cells and macrophages, is relevant to pulmonary disease in cystic fibrosis (CF), fecal levels have not yet been assessed in children with CF. Fecal CHI3L1 was measured with a commercial immunoassay using fecal samples provided by children with CF and healthy control (HC) children. Higher median (interquartile range) fecal CHI3L1 levels were seen in the 52 children with CF than in the 35 controls: 15.97 (3.34–50.53) ng/g versus 2.93 (2.13–9.27) ng/g (P = 0.001). Fecal CHI3LI did not differ according to sex. In the children with CF, fecal CHI3L1 l...
Source: Journal of Pediatric Gastroenterology and Nutrition - July 1, 2022 Category: Gastroenterology Tags: Short Communications: Gastroenterology Source Type: research

Changes in Glucose Breath Test in Cystic Fibrosis Patients Treated With 1 Month of Lumacaftor/Ivacaftor
Conclusion: We found a high rate of positive hydrogen breath tests in individuals with CF, confirming that SIBO is common. One month of luma/iva did not significantly change the proportion of those with positive breath hydrogen measurements. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Impact of Pancreatic Enzymes on Enteral Fat and Nitrogen Absorption in Short Bowel Syndrome
Conclusions: There was no statistically significant improvement in enteral fat and protein absorption in the cohort as a whole, though several subjects demonstrated an improvement. These results suggest that some patients with SBS may benefit from treatment with pancreatic enzymes. Further studies are needed to better evaluate the effect of pancreatic enzyme therapy on enteral absorption in subjects with SBS and to characterize factors that may predict a positive response. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

A Study of Postoperative Complications Occurring at Home With Pediatric Gastrostomy Feeding Tubes
Conclusions: G-tube complications are prevalent and varied. A sizable portion of G-tube users experience complications severe enough to require intervention. Of these, G-tube displacement is particularly critical and frequently precedes other prevalent complications, namely gastric leakage, infection, and tissue granulation. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Long-Term Follow-up of Individual Therapist Delivered and Standardized Hypnotherapy Recordings in Pediatric Irritable Bowel Syndrome or Functional Abdominal Pain
Conclusions: Both home-based treatment with standardized-hypnosis-recordings and iHT given by a therapist show persisting positive results in more than 80% of children with IBS and FAP(S) after 6 years of follow-up. These results support the rationale for implementation of this easy-to-use, widely available and cost-effective home-treatment in daily practice. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Prevalence of Functional Gastrointestinal Disorders in Brazilian Infants Seen in Private Pediatric Practices and Their Associated Factors
Objectives: To assess the prevalence of the most frequent functional gastrointestinal disorders (FGIDs) in Brazilian infants seen in private pediatric clinics and their relationship with cesarean delivery, breastfeeding, and history of prematurity. Methods: This cross-sectional study enrolled 5080 infants under 12 months old with routine visits in private pediatric clinics in Brazil. The mothers answered questions about the type of delivery, type of feeding (breast milk, infant formula, cow milk, mixed feeding), history of prematurity, and gastrointestinal symptoms. Rome IV criteria were used to diagnose FGIDs. ...
Source: Journal of Pediatric Gastroenterology and Nutrition - July 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Analysis of Neurogastrointestinal and Motility Disorders From the National Pediatric Database (Kid’s Inpatient Database): Exploring Demographic Access and Outcomes
The objective of our study is to characterize the demographic and hospitalization trends of patients undergoing PNGM tests. Methods: We used Healthcare Cost and Utilization Project (HCUP) Inpatient Database (KID) for years 2003–2016 to perform a trend analysis in US hospitalizations for International Classification of Diseases (ICD)-9 and -10 Clinical Modification (CM)–identified PNGM studies in patients ( (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Inpatient Care Utilization and Epidemiology of Hirschsprung Disease: Analysis of the National Inpatient Sample
Conclusion: Increasing cost of HD-related hospitalization despite decreasing LOS was observed in this cohort. Stable rate of hospitalizations with increasing proportions of pull-through procedures among neonates was noted. Future studies and development of protocols to standardize patient care could improve outcomes and healthcare spending. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 1, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

How Exclusive Does Exclusive Enteral Nutrition Need to Be to Be Effective?
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 1, 2022 Category: Gastroenterology Tags: Invited Commentary Source Type: research

Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Proposal of a Questionnaire for Acute Food Protein-induced Enterocolitis Syndrome Diagnosis
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

How Broad Should Gram-Negative Coverage Be for Febrile Parenteral Nutrition Dependent Short Bowel Syndrome Patients?
Broader spectrum Gram-negative antibiotics are commonly utilized empirically for central line-associated bloodstream infections (CLABSI) in febrile short bowel syndrome (SBS) patients receiving home parenteral nutrition compared to those used empirically for inpatient-acquired CLABSI. This analysis reports 57 CLABSI in 22 patients with SBS admitted from the community and 78 inpatient-acquired CLABSI in 76 patients over a 5-year period. Proportional Gram-negative CLABSI was similar between the SBS and inpatient-acquired cohorts (43.8% vs42.3%, respectively, P  = 0.78). 1.8% and 10.3% (P = 0.125) of...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Short Communication: Nutrition Source Type: research

Intestinal Inflammation is Significantly Associated With Length Faltering in Preterm Infants at Neonatal Intensive Care Unit Discharge
Objective: The aim of the study was to assess intestinal inflammatory measures, urinary intestinal fatty acid-binding protein (IFABP), and fecal calprotectin (FC) by gestational age (GA) and postmenstrual age (PMA) and determine the association between intestinal inflammation and growth in preterm infants from birth to hospital discharge. We hypothesized that intestinal inflammation is associated with adverse growth in preterm infants. Methods: We assayed repeated measures of IFABP and FC in 72 hospitalized preterm infants ( (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Aricle: Nutrition and Growth Source Type: research

Impact of Nutrition Support Team in Achieving Target Calories in Children Admitted in Pediatric Intensive Care Unit
Objective: To determine the impact of nutrition support team (NST) on achieving an early target caloric goal in mechanically ventilated children admitted in pediatric intensive care unit (PICU). Methods: An early enteral nutrition protocol (EENP) was implemented by NST to ensure early and adequate nutrition provision to PICU patients. All children (1 month– 18 years) that were admitted in PICU for>2days and received mechanical ventilation, with no contraindications to enteral feed, were included and data was compared with those of pre-intervention. The adequacy of energy intake was defined as 70% achievement...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research

Infant Formulas With Postbiotics: An Updated Systematic Review
Conclusions: IF with postbiotics evaluated so far are safe and well tolerated by infants who cannot be breastfed. No firm conclusion can, however, be reached regarding the clinical effects and benefit of one formula over another. It seems reasonable to discuss with healthcare providers current evidence regarding specific modifications in infant formulas and let them decide whether the expected benefits meet expectations and are worth the cost. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2022 Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research