Pediatric Liver Transplant Survival in Alagille Syndrome Is Comparable to Biliary Atresia—A Linked Database Analysis
Conclusions: Despite increased rate of congenital heart defects and cardiac interventions, higher creatinine, and higher laboratory MELD/PELD scores at time of transplant, this study demonstrates that there is no difference in either patient or graft survival between patients with ALGS and BA. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - September 1, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Long-Term Growth in Children and Young People with Autoimmune Liver Disease Treated with Daily Steroids
Objectives: We aimed to evaluate long-term growth in children and young people with autoimmune liver disease (AILD) treated with daily steroids. Methods: This is a retrospective observational cohort study of patients diagnosed between 1992 and 2004 before the age of 16 years. Growth measurements (height, weight and body mass index (BMI)) converted to z-scores were recorded, at diagnosis, 1 and 5 years after commencing treatment and at age 18 years and analyzed together with demographics, disease and treatment related characteristics. Results: Seventy-four patients (35 female) were started on treatment at ...
Source: Journal of Pediatric Gastroenterology and Nutrition - September 1, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Long COVID-19 Liver Manifestation in Children
Conclusions: We report 2 distinct patterns of potentially long COVID-19 liver manifestations in children with common clinical, radiological, and histopathological characteristics after a thorough workup excluded other known etiologies. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - September 1, 2022 Category: Gastroenterology Tags: Rapid Communication: Hepatology Source Type: research

Postpyloric Feeding Access in Infants and Children: A State of the Art Review
This article provides a practical summary of the literature on the different methods utilized to achieve postpyloric feeding access including bedside, fluoroscopic, endoscopic and surgical options. Indications and complications of these methods are discussed as well as a general approach to infants and children that require intestinal feeding. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - September 1, 2022 Category: Gastroenterology Tags: Review Articles Source Type: research

Peroral Endoscopic Myotomy (POEM) in Children: A State of the Art Review
Esophageal achalasia is a relatively rare disease in children that has been treated with balloon dilatation, botulinum toxin injection, and Heller myotomy. Peroral endoscopic myotomy (POEM) is another treatment that has been successfully employed to treat adults with achalasia for over a decade and has been increasingly used in children. This State of the Art Review from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Endoscopy Committee reviews the current literature in pediatric POEM including the technique, success rate, complications as well as training guidelines. Though there is li...
Source: Journal of Pediatric Gastroenterology and Nutrition - September 1, 2022 Category: Gastroenterology Tags: Review Articles Source Type: research

Revisiting Methotrexate Therapy for Pediatric Crohn Disease
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - September 1, 2022 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

Chevalier Jackson, the Small Part Test Fixture Tube, the 10th Circuit Court and COVID-19: Impact on Pediatric Foreign Body Ingestions in the United States
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - September 1, 2022 Category: Gastroenterology Tags: Invited Commentaries Source Type: research

Successful Endoscopic Reduction of Gastric Volvulus in 2 Children: Acute and Chronic Cases
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 28, 2022 Category: Gastroenterology Tags: Video of the Month Source Type: research

Giant Filiform Polyposis of the Colon in a 6-Year Old Male With Ulcerative Colitis
No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 28, 2022 Category: Gastroenterology Tags: Image of the Month Source Type: research

Physician and Parent Perceptions on Plant-Based Beverages as Substitutes for Cow’s Milk: A Single City Survey
This study assessed physician and parent perceptions regarding plant-based beverage consumption in children. We surveyed 128 physicians and 215 parents of patients at University of Miami and Jackson Memorial Hospital. Among physicians, 52% recommended plant-based beverages, typically soy (33%), for cow’s milk allergy (32%). Only 40% of physicians knew the typical protein content of plant-based beverages compared to cow’s milk. Most physicians (54%) did not discuss potential health risks of plant-based beverages with patients. Among parents, 48% had children (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 28, 2022 Category: Gastroenterology Tags: Short Communication: Nutrition Source Type: research

Evaluating the Dietary Intake of Children With Esophageal Atresia: A Prospective, Controlled, Observational Study
Conclusions: Children with EA have similar energy intake and growth parameters to HC, but their diet consists of a higher proportion of fats and lower proportion of carbohydrates compared to HC. Targeted dietary interventions and parental education are necessary. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 28, 2022 Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research

Goat Milk Based Infant Formula in Newborns: A Double-Blind Randomized Controlled Trial on Growth and Safety.
Objectives: We aimed to determine the growth and safety parameters in newborns fed a goat milk based infant formula (GMF) using a randomized double-blind trial, in which a cow milk formula (CMF) served as a control and a breast fed (BF) group as a reference. Methods: Healthy term infants (n = 218) aged up to 14 days were recruited from 25 European study centers and randomized to GMF or CMF. Weight, length, head circumference were measured at baseline, and at 14, 28, 56, 84, and 112 days at the study clinics. Adverse events were recorded and stool characteristics, reflux, fussiness, colic, and flatulence were sel...
Source: Journal of Pediatric Gastroenterology and Nutrition - July 28, 2022 Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research

Novel Pediatric Height Outlier Detection Methodology for Electronic Health Records via Machine Learning With Monotonic Bayesian Additive Regression Trees
Conclusions: We have developed a new reliable, largely automated, outlier detection method which is applicable to the identification of height outliers in the pediatric EHR. This methodology can be applied to assess the veracity of height measurements ensuring reliable indices of body proportionality such as body mass index. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 28, 2022 Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research

Feeding in Preterm Neonates With Antenatal Doppler Abnormalities: A Systematic Review and Meta-Analysis
Conclusion: There is low-certainty evidence that early feed initiation in preterm neonates with antenatal Doppler abnormalities does not increase rates of NEC and mortality. There is insufficient data on the speed of feed advancement. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - July 28, 2022 Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research

Cholangioscopy in Children and Adolescents: Utilization, Outcomes, and Safety
Conclusions: These data attest to the safety and clinical utility of cholangioscopy in children and adolescents. Cholangioscopy was performed in just over 11% of pediatric patients who underwent ERCP at our academic medical center—rates similar to those reported in adult patients. The radiation-sparing nature of cholangioscopy, coupled with these data supporting its safety, make it particularly appealing for use in children. Further multi-institution evaluation of the utility, safety, and range of indications for cholangioscopy in other practice settings would be of great interest and help guide endoscopic care. (Sou...
Source: Journal of Pediatric Gastroenterology and Nutrition - July 28, 2022 Category: Gastroenterology Tags: Original Article: Endoscopy and Procedures Source Type: research