Periodicity of Ascaridia galli egg excretion in experimentally infected chicken in the Philippines
We examined the fecal egg per gram (EPG) count at 3-h intervals for 3 days, starting from 5:00 –6:00 h AM to the following day at 1:00–2:00 h AM. Our results showed a consistent daily egg excretion pattern with a peak EPG count in the morning that abruptly declined in the afternoon and lowest in the evening. The EPG counts correlated with the amount of excreta produced, suggesting thatA. galli fecundity corresponds to the timing of host defecation. Our results imply that the best time to collect fecal samples forA. galli diagnosis and FECRT in Philippine conditions should be from sunrise until late morning when paras...
Source: Journal of Parasitic Diseases - January 2, 2024 Category: Parasitology Source Type: research

Enteric parasites and associated factors in cancer patients in Nepal
This study aimed to investigate the prevalence and risk factors of intestinal parasitic infections (IPIs) among cancer patients undergoing chemotherapy at Nepal Cancer Hospital and Research Center (NCHRC) in Nepal. One hundred individuals were selected with a convenience sampling strategy. The stool samples were examined by direct wet mount, sedimentation, flotation, and acid-fast methods to determine the prevalence and intensity of IPIs in this population. The overall prevalence of IPIs was 8% (4% protozoan and 4% helminths). Altogether, three species of intestinal parasites were detected.Cryptosporidium (4%) was predomin...
Source: Journal of Parasitic Diseases - December 6, 2023 Category: Parasitology Source Type: research

Modulation of CXCL10 activity as a therapeutic target of ocular toxoplasmosis in diabetic mice
In conclusion, Optimal control of pathogens probably needs a balanced immune response with an optimu m expression of chemokines. So, targeting the modulation of retinal CXCL10 may eventually be beneficial in the management of ocular toxoplasmosis plus its potential to act as a marker for predictive local immunological response during the infection. (Source: Journal of Parasitic Diseases)
Source: Journal of Parasitic Diseases - December 5, 2023 Category: Parasitology Source Type: research

Serological and molecular detection of Toxoplasma gondii in ß. thalassemia patients
AbstractToxoplasma gondii is a worldwide opportunistic protozoan causing life-threatening infection in immunocompromised patients, while frequently asymptomatic in immunocompetent individuals. The current study aimed to detectT. gondii; serologically and molecularly in ß. thalassemia patients and evaluate the association of infection with some hematological parameters in these patients. Blood samples were collected from 100 ß. thalassemia patients. Serological diagnosis ofT. gondii using ELISA for IgG and IgM antibodies was performed. Molecular diagnosis by Real-Time (RE) PCR was performed using specifically designed pri...
Source: Journal of Parasitic Diseases - November 24, 2023 Category: Parasitology Source Type: research

Community structure, seasonal dynamics, and impact of some biological parameters of the African catfish Clarias gariepinus on the infection level of the helminth parasites
AbstractFish parasitic diseases impose a major economic concern on aquaculture. Identified parasites ofClarias gariepinus include one monogenean,Macrogyrodactylus clarii (gills), three digeneansOrientocreadium batrachoides, Eumasenia bangweulensis andSanguinicola sp. (intestine), two cestodesTetracampose ciliotheca and Monobothrioides chalmersius (intestine) and two nematodesParacamallanus cyathopharynx and Procamallanus pseudolaeviconchus (intestine and stomach). Most nematodes, digeneans and cestodes occurred in all months of the study period. However,M. clarii andSanguinicola sp. disappeared for 6 and 8  months of the ...
Source: Journal of Parasitic Diseases - November 24, 2023 Category: Parasitology Source Type: research

Evaluation of the therapeutic efficacy of some essential oils in experimentally immunosuppressed mice infected with Cryptosporidium parvum
AbstractCryptosporidiosis is a serious intestinal disease affecting mal-nourished children and immunocompromised individuals with severe fatal diarrhea. Our present work was done to evaluate the possible curative effects of different essential oils (Mint, Thyme, Chamomile and Basil) onCryptosporidium parvum (C. parvum) in vivo compared with nitazoxanide (NTZ). Seventy immunosuppressed white Albino male mice were allocated in 7 groups as follows: group I infected and not treated (Positive control), group II (GII) treated with NTZ, group III (GIII) treated with Mint essential oil, group IV (GIV) treated with Thyme essential ...
Source: Journal of Parasitic Diseases - November 24, 2023 Category: Parasitology Source Type: research

In vivo efficacy of silver nanoparticles against Syphacia muris infected laboratory Wistar rats
In conclusion, this is the first in vivo study to evaluate Ag NPs efficacy againstS. muris in laboratory rats without significant toxicity. (Source: Journal of Parasitic Diseases)
Source: Journal of Parasitic Diseases - November 24, 2023 Category: Parasitology Source Type: research

Epidemiological characteristics of human cystic echinococcosis in Khuzestan province (Iran), 2011 –2021: a retrospective analytical study
This study investigated the epidemiological dimensions of HC in patients admitted to hospitals in Khuzestan province from 2011 to 2021. Of all 183 patients identified, 113 (61.7%) were female with the mean age of 37.7  ± 17, men with the mean age of 36.7 ± 19. Also, we found that housewives made up 49.2% of our HC patients. 65% of the patients in this study lived in urban areas, and 42% had a history of contact with dogs. The liver was reported to be the most HC-affected organ. The most clinical symptom s were abdominal pain and hepatomegaly. 59% of the patients had only one cyst. This study found that surgery an...
Source: Journal of Parasitic Diseases - November 24, 2023 Category: Parasitology Source Type: research

Hand palm sparganosis: morphologically and genetically confirmed Spirometra erinaceieuropaei in a fourteen-year-old girl, Egypt
AbstractTwo spargana of 5 and 7  cm long were removed from the right-hand palm of 14-year-old girl at the General Hospital, Qalyubia, Egypt. Sparganum is the 2nd larval stage (pleurocercoid) of Diphyllobothrid cestode species develops in the vertebrate second intermediate host through ingestion of the crustacean first intermediat e host.Dogs and cats are the final hosts get infected through predation of the second vertebrate host.Human attracts infection through drinking water contaminated with the infected crustacean host or consumption of the flesh of of vertebrate hosts such as frogs and reptilian species. The surgical...
Source: Journal of Parasitic Diseases - November 24, 2023 Category: Parasitology Source Type: research

Genotyping of Echinococcus granulosus isolated from canine in Northwest Iran
This study aimed to investigate the genotypes ofE. granulosus isolated from canines in the northwest of Iran. A total of 87 samples were collected from the Mughan plain area in Ardabil province, including 47 stray dogs (Canis familiaris), 25 golden jackals (Canis aureus), and 15 red foxes (Vulpes vulpes), and molecular analysis was performed for partial cytochrome c oxidase subunit 1 and nad1 genes. Phylogenetic analyses were carried out on the obtained sequence. The findings revealed that 9 out of 87 (10.3%) samples were infected withEchinococcus parasites, with a frequency of 1 (4%) and 8 (17%) among golden jackals and s...
Source: Journal of Parasitic Diseases - November 24, 2023 Category: Parasitology Source Type: research

First record of the genus Paratrichodina (Ciliophora: Trichodinidae) in India from ornamental goldfish (Carassius auratus L.) supplemented with description of a new species Paratrichodina indiana n. sp.
AbstractThe present investigation deals with the accounts of a novel species of ciliate parasite belonging to the genusParatrichodina namely,Paratrichodina indiana n. sp. identified from the respiratory organ of goldfishCarassius auratus at Nadia district of West Bengal, India. 276 fish have been collected for parasitological examination from various fish farm of West Bengal, India. The parasitological investigation was conducted using the AgNO3 impregnation technique, which was supplemented by a taxonomic description, morphological variations and data comparison with previously documented closely related species.Paratrich...
Source: Journal of Parasitic Diseases - November 24, 2023 Category: Parasitology Source Type: research

Hematological characteristics of autochthonous hypermicrofilaremic dirofilariosis in dogs in Kannur District of Kerala
This study aimed to determine whether autochthonous high-intensityD. repens microfilaremia leads to haematological changes in companion dogs. Dogs with hypermicrofilaremia presented to the District Veterinary Centre, Kannur were selected for the study. A total of 100 dogs were positive for hypermicrofilariaemia withD. repens based on peripheral blood smear examination and Knott ’s test. Of these, 3 dogs were concurrently positive for sheathed microfilaria (MF) ofBrugia spp. Interestingly, an adult live worm ofD. repens approximately eight cm in length was detected on a subcutaneous mass on the hind limb of a hypermicrofi...
Source: Journal of Parasitic Diseases - November 24, 2023 Category: Parasitology Source Type: research

Six species of nonmazocraeid monogeneans including two new species from clupeiform fishes of Visakhapatnam coast, Bay of Bengal
AbstractDuring a survey on monogenean parasites of clupeiform fishes of Visakhapatnam coast, Bay of Bengal, apart from typical mazocraeids, 6 species of nonmazocraeids, including two new species were encountered. These belonged to 5 genera distributed over 4 families: Family Gastrocotylidae:Engraulicola thrissocles fromThryssa mystax, T. setirostris, T. malabarica;Engraulicola longisomum n.sp. fromThryssa mystax, T. setirostris, T. malabarica;Pellonicola elongatus fromIlisha filigera; family Megamicrocotylidae:Megamicrocotyle chirocentrus fromChirocentrus dorab; family Microcotylidae:Microcotyle clupei n.sp. fromThryssa my...
Source: Journal of Parasitic Diseases - November 24, 2023 Category: Parasitology Source Type: research

Cloning, expression and purification of Eimeria maxima gametocyte antigen-EmGam56 for control of poultry coccidiosis
AbstractPoultry coccidiosis is an important devitalizing enteric protozoan disease caused by a group of obligatory intracellular apicomplexan parasites of the GenusEimeria contributing to major economic loss in commercial poultry worldwide. As the current method of chemotherapeutic control using ionophores in feed had led to development of drug resistant isolates, the need for development of prophylactic vaccines is the most viable alternate and eco-friendly control strategy as on date. Of the several candidate vaccines, theEmGam 56 is one of the most promising candidates which protect the birds againstE. maxima,E. tenella...
Source: Journal of Parasitic Diseases - November 24, 2023 Category: Parasitology Source Type: research

Source tracking of fecal contamination in Asian green mussels (Perna viridis) harvested in Manila Bay, Philippines by molecular detection and genotyping of Cryptosporidium spp.
AbstractManila Bay, a multipurpose body of water located around Metro Manila, Philippines, is progressively deteriorating because of massive pollution. Reports have shown that the bay and its aquatic resources (i.e., seafood) are contaminated with fecal matter and enteric pathogens, posing a threat to public health and industry. This problem raises the need for a microbial source tracking methodology as a part of the rehabilitation efforts in the bay. Bivalve mollusks cultivated in water can serve as sentinel species to detect fecal pollution and can complement water monitoring. With the use of polymerase chain reaction an...
Source: Journal of Parasitic Diseases - November 22, 2023 Category: Parasitology Source Type: research