Remarks on Eimeria labbeana infection in domestic pigeons “Columbia livia domestica”
AbstractThe purpose of this study was to determine the course of infection in pigeons withEimeria labbeana. Thirty-five squabs (4 –6 weeks old) were brought from the local poultry market and examined for coccidial infection for 7 days to ensure they were coccidia free. A negative control group of five squabs was used, and thirty squabs were infected orally with 2.5?×?104 sporulatedE. labbeana oocysts. From day 1 –8 post-infection (PI), three squabs were scarified daily to track the endogenous stages in the intestinal tissue. Furthermore, six squabs were preserved to track the patent period and calculate daily oocyst sheddi...
Source: Journal of Parasitic Diseases - December 1, 2021 Category: Parasitology Source Type: research

First report of Lophomonas spp. in German cockroaches (Blattella germanica) trapped in hospitals, northern Iran
AbstractCockroaches are considered to be important reservoirs for protozoan and helminth parasites,particularly an emergingLophomonas spp., protozoan parasite. German cockroaches,Blattella germanica (B. germanica), are domestic pest distributed worldwide. However, little information is available regarding the burden ofLophomonas spp. infestation among domestic cockroach population worldwide. The present study investigated parasitic agents, emphasizingLophomonas spp. infestation amongB. germanica in northern Iran. During spring and summer 2018, a total of 496 adultsB. germanica (265 males and 231 females) were trapped by ha...
Source: Journal of Parasitic Diseases - October 30, 2021 Category: Parasitology Source Type: research

Prevalence of Filariasis in camels (Camelus dromedarius) in Upper Egypt with special reference to treatment
AbstractThe study aimed to detect the prevalence of camel filariasis in Upper Egypt, the effect of age, sex, season, locality and periodicity of sampling and treatment of infested cases and also determines the diagnostic technique for detection of the parasite. The study carried out on a total number of 350 camels (Camelus dromedarius) belonged to different Governorates in Upper Egypt including Assuit, Sohag, Asswan and El-wady El-gaded, by using the following methods for diagnosis of camel filariasis, wet blood film, thin blood film, thick blood film and concentration technique (Knott's technique). From the total number o...
Source: Journal of Parasitic Diseases - October 30, 2021 Category: Parasitology Source Type: research

The potentials of Calotropis procera against filarial elephantiasis: an in-silico approach
This study aims at the identification of a natural molecule that has the potential to bind with the GST enzyme, which plays a major role in detoxification of endogenous electrophilic compounds. Thus the binding interrupts the detoxification process within the filarial parasite,Brugia malayi. A medicinal plantCalotropis procera, owing to its anthelmintic properties was searched for the presence of potential phytocompounds. The phytocompounds were docked against the homology modeled GST enzyme using the MOE software. The results were screened and analyzed based on the Lipinski rule of 5. N-octanoate was the phytocompound obt...
Source: Journal of Parasitic Diseases - October 19, 2021 Category: Parasitology Source Type: research

Anti-Leishmania infantum in vitro effect of n-cyclohexyl-1,2,4-oxadiazole and its ADME/TOX parameters
AbstractLeishmaniasis is a disease that represents a serious global health problem with a potentially fatal outcome in some cases.Leishmaniaspp. is transmitted by the bite of a sandfly and the disease is endemic in 98 countries. Treatment is carried out with toxic drugs and not consistently effective, so there is a need for new treatments. Oxadiazoles are five-membered heterocyclic compounds, and their antileishmanial activity is well documented in the literature. Specifically,n-cyclohexyl-1,2,4-oxadiazole (2b) was designed to obtain the simplified molecular data line entry system (SMILES). The approach for predicting phar...
Source: Journal of Parasitic Diseases - October 6, 2021 Category: Parasitology Source Type: research

Expression and production of protoscolex recombinant P29 protein and its serological evaluation for diagnosis of human hydatidosis
AbstractCystic Echinococcosis/Hydatidosis considered as one of the most important parasitic diseases in humans and animals across the world. The goal of the present study was to determine a native antigen with an acceptable sensitivity and specificity to be used in the human hydatid cyst diagnostic methods. In the present study, recombinant P29 antigen was used to detect the antibodies in the serum of patients with hydatid cysts of the liver. In fact, purified recombinant P29 protein is used as an antigen in ELISA. In order to evaluate the recombinant P29 protein for diagnostic ELISA, 25 serums obtained from people harbori...
Source: Journal of Parasitic Diseases - September 29, 2021 Category: Parasitology Source Type: research

In vitro efficacy of polymer coated miltefosine drug against leishmania tropica
In conclusion, MFS-CNPs manifested enhanced in vitro Leishmanicidal and less hemolytic a ctivity; however more studies are needed to support its efficacy in both animal and human cutaneous leishmaniasis. (Source: Journal of Parasitic Diseases)
Source: Journal of Parasitic Diseases - September 23, 2021 Category: Parasitology Source Type: research

Onchocerca flexuosa. sp. (Nematoda: Filarioidea) in Japanese Wild Sika Deer (Cervus nippon): Pathological and molecular identification
AbstractSubcutaneous nodular onchocercosis was detected and investigated in 17 Japanese Sika deer (Cervus nippon), captured in Gifu and Shiga Prefectures/Japan, in the period between 2016 and 2017. The worms were found in all the seventeen deer within characteristics subcutaneous nodules dispersed mainly in the back (especially in the lumbar region and flanks), with few scattered nodules were located at the forelimbs and neck. The all collected nodules were examined stereo-microscopically. The parasites were extracted from the nodules and identified through morphological and histopathological examinations. Molecular identi...
Source: Journal of Parasitic Diseases - September 23, 2021 Category: Parasitology Source Type: research

In vivo antiplasmodial activities and acute toxicity assessment of two plant cocktail extracts commonly used among Southwestern Nigerians
This study investigated the efficacies of two plant cocktails; CtA and CtB, selected based on their traditional usage. Efficacies of the cocktail extracts, chloroquine and pyrimethamine againstPlasmodium berghei berghei were evaluated in mice using the suppressive, curative and prophylactic test models, after oral and intraperitoneal acute toxicity determination of the plant cocktails in accordance with Lorke ’s method. Data was analyzed using SPSS software version 23.0 with level of significance set atP <  0.05. The median lethal dose was determined to be higher than 5000 mg/kg body weight orally for both CtA an...
Source: Journal of Parasitic Diseases - September 14, 2021 Category: Parasitology Source Type: research

Acute toxoplasmosis can increase serum dopamine level
This study aimed to evaluate serum dopamine levels in acute murine toxoplasmosis. In this study, 50 mice infected withToxoplasma were studied in 5 separate groups, and ten healthy mice were considered as negative control. For five consecutive days after parasite injection, blood sampling and serum isolation were performed daily from one of the groups. Serum dopamine levels were measured by HPLC method. Statistical studies showed that serum dopamine on the first to the fourth day after parasite inoculation was the same as the negative control, but the fifth day began to increase. The present study results indicate that dopa...
Source: Journal of Parasitic Diseases - September 14, 2021 Category: Parasitology Source Type: research

First report on the diversity and distribution of parasitic monogenoids (Platyhelminthes) from catfishes (Siluriformes) in Arunachal Pradesh, India
In this study, 21 species of catfishes were collected and examined with the aim of expanding the current knowledge of the diversity and distribution of monogenoid species from Arunachal Pradesh. 15 (62.5%) of the 21 catfish species studied were infecte d with a total of 25 monogenoid species (11 previously described and 14 newly discovered in this study). Ten species of catfish were thefirst host records for new parasite species, while two species of catfish werenew host records for previously known monogenoids. Arunachal Pradesh represents new geographic locality records for all 11 previously described parasite species, t...
Source: Journal of Parasitic Diseases - September 12, 2021 Category: Parasitology Source Type: research

Isopod parasite, Nerocila depressa Milne Edwards, 1840 infestation in Thryssa stenosoma Wongratana, 1983, as a first record from Narmada estuary, West Coast of India
AbstractThe study reportedThryssa stenosoma, as a new host of isopodNerocila depressa infestation. Furthermore, the record ofNerocila depressa from the Narmada estuary is of first kind in the West Coast of India.Thryssa stenosoma, commonly known as slender thryssa forms an important commercial fish species at Bhadbhut, a part of the Narmada estuary. The prevalence ofN. depressa infestation was 17.39% with a mean intensity of 2.8. inT. stenosoma, showing a low rate of infestation. The present information would form a new addition of isopod infestation to the list of parasitic diseases of estuarine fishes in India. (Source: ...
Source: Journal of Parasitic Diseases - September 12, 2021 Category: Parasitology Source Type: research

New record of two isopods Alitropus typus and Tachaea spongillicola from riverine freshwater fishes in the river Tapti
AbstractThe present paper deals with the infestation of freshwater fishesLabeo boggut, Oreochromis niloticus, Systomus sarana, andXenentodon cancila by the parasitic isopodsAlitropus typus andTachaea spongillicola in Tapti, a westward freshwater flowing river of India. The isopodsAlitropus typus H. Milne Edwards, 1840 andTachaea spongillicola Stebbing, 1907 were identified with the taxonomic keys of Milne Edwards (1840) and Stebbing (1907), respectively. It is the first record of the infestation of parasitic isopodsAlitropus typus, andTachaea spongillicola in the freshwater fishes of river Tapti with new hosts ’ speciesL...
Source: Journal of Parasitic Diseases - September 10, 2021 Category: Parasitology Source Type: research

Religion and gender behavior: understanding the variations in risk to urinary schistosomiasis among farmers
AbstractUrinary schistosomiasis is a chronic and acute disease that is widely spread among the poor. It is caused by blood fluke of the genusSchistosoma, and transmitted to humans through water related activities by way of skin penetration. While schistosomiasis is rarely fatal, it could impact negatively on the economy and health status of infected individual. We evaluated the prevalence and dissimilarity of schistosomiasis among farmers in a cross sectional study, while grouping the farmers into different categories. Prior to the initiation of the study, we sought permission from the community head (Emir) and properly en...
Source: Journal of Parasitic Diseases - September 9, 2021 Category: Parasitology Source Type: research

Detecting Schistosoma haematobium infection by microscopy and polymerase chain reaction (PCR) in school children in three senatorial districts of Cross River State, Nigeria
This study has shown PCR to be effective in detecting schistosomiasis infection and also re-affirms the endemicity of urinary schistosomiasis in the three Senatorial Districts of CRS. (Source: Journal of Parasitic Diseases)
Source: Journal of Parasitic Diseases - September 2, 2021 Category: Parasitology Source Type: research