Lyophilized apoptotic vesicle-encapsulated adhesive hydrogel sponge as a rapid hemostat for traumatic hemorrhage in coagulopathy
Rapid hemostasis of uncontrolled bleeding following traumatic injuries, especially accompanied by coagulopathies, remains a significant clinical challenge. Extracellular vesicles (EVs) show therapeutic effects... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 3, 2023 Category: Nanotechnology Authors: Yexiang Jiang, Meng Hao, Fenglin Jiang, Jiwu Li, Kunkun Yang, Can Li, Lan Ma, Shiyu Liu, Xiaoxing Kou, Songtao Shi, Xin Ding, Xiao Zhang and Jianxia Tang Tags: Research Source Type: research

Nanoengineered injectable hydrogels derived from layered double hydroxides and alginate for sustained release of protein therapeutics in tissue engineering applications
Chronic Kidney Disease (CKD) which involves gradual loss of kidney function is characterized by low levels of a glycoprotein called Erythropoietin (EPO) that leads to red blood cell deficiency and anemia. Rec... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 2, 2023 Category: Nanotechnology Authors: V. H. Giang Phan, Hai-Sang Duong, Quynh-Giao Thi Le, Gopinathan Janarthanan, Sanjairaj Vijayavenkataraman, Hoang-Nam Huynh Nguyen, Bich-Phuong Thi Nguyen, Panchanathan Manivasagan, Eue-Soon Jang, Yi Li and Thavasyappan Thambi Tags: Research Source Type: research

Recent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and update
Despite the existence of numerous eye drops in the market, most of them are not sufficiently effective because of quick clearance and the barriers within the eye. To increase the delivery of the drugs to the e... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 2, 2023 Category: Nanotechnology Authors: Roghayyeh Baghban, Mohammad Reza Talebnejad, Aidin Meshksar, Mojtaba Heydari and Mohammad Reza Khalili Tags: Review Source Type: research

High-precision detection and navigation surgery of colorectal cancer micrometastases
Surgical resection is an effective treatment for colorectal cancer (CRC) patients, whereas occult metastases hinder the curative effect. Currently, there is no effective method to achieve intraoperatively diag... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 2, 2023 Category: Nanotechnology Authors: Shengjie Ma, Bin Sun, Mengfei Li, Tianyang Han, Chenlong Yu, Xin Wang, Xue Zheng, Shuang Li, Shoujun Zhu and Quan Wang Tags: Research Source Type: research

Injectable hydrogel loaded with lysed OK-432 and doxorubicin for residual liver cancer after incomplete radiofrequency ablation
To investigate the efficacy of an injectable hydrogel loaded with lysed OK-432 (lyOK-432) and doxorubicin (DOX) for residual liver cancer after incomplete radiofrequency ablation (iRFA) of hepatocellular carci... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 2, 2023 Category: Nanotechnology Authors: Yanyan Cao, Tao Sun, Bo Sun, Guilin Zhang, Jiayun Liu, Bin Liang, Chuansheng Zheng and Xuefeng Kan Tags: Research Source Type: research

Engineered extracellular vesicles for ischemic stroke: a systematic review and meta-analysis of preclinical studies
This systematic review and meta-analysis aimed to evaluate the efficacy of engineered extracellular vesicles (EEVs) in the treatment of ischemic stroke (IS) in preclinical studies and to compare them with natu... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - October 31, 2023 Category: Nanotechnology Authors: Pengtao Li, Rui Yin, Yihao Chen, Jianbo Chang, Lang Yang, Xiaoyu Liu, Houshi Xu, Xiao Zhang, Shihua Wang, Qin Han and Junji Wei Tags: Methodology Source Type: research

Coordinated modulation of long non-coding RNA ASBEL and curcumin co-delivery through multicomponent nanocomplexes for synchronous triple-negative breast cancer theranostics
Abnormally regulated long non-coding RNAs (lncRNAs) functions in cancer emphasize their potential to serve as potential targets for cancer therapeutic intervention. LncRNA ASBEL has been identified as oncogene... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - October 31, 2023 Category: Nanotechnology Authors: Xuesong He, Fengjuan Lin, Runqing Jia, Yang Xia, Zhaoyuan Liang, Xiangqian Xiao, Qin Hu, Xiongwei Deng, Qun Li and Wang Sheng Tags: Research Source Type: research

Engineering liquid metal-based nanozyme for enhancing microwave dynamic therapy in breast cancer PDX model
The novel concept of microwave dynamic therapy (MDT) solves the problem of incomplete tumor eradication caused by non-selective heating and uneven temperature distribution of microwave thermal therapy (MWTT) i... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - October 31, 2023 Category: Nanotechnology Authors: Qiong Wu, Yongnian Yu, Xiaorui Yu, Qijun Du, Li Gou, Longfei Tan, Changhui Fu, Xiangling Ren, Jun Ren, Kai Xiao and Xianwei Meng Tags: Research Source Type: research

Glucose oxidase and metal catalysts combined tumor synergistic therapy: mechanism, advance and nanodelivery system
Cancer has always posed a significant threat to human health, prompting extensive research into new treatment strategies due to the limitations of traditional therapies. Starvation therapy (ST) has garnered co... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - October 31, 2023 Category: Nanotechnology Authors: Yuhan Fu, Jialin Sun, Yanhong Wang and Weinan Li Tags: Review Source Type: research

Targeting and repolarizing M2-like tumor-associated macrophage-mediated MR imaging and tumor immunotherapy by biomimetic nanoparticles
Anti-tumor M1-like and pro-tumor M2-like tumor-associated macrophages (TAMs) coexist in tumor microenvironments (TME). The adverse effects of these M1/M2 subsets on tumors directly affect the current strategie... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - October 31, 2023 Category: Nanotechnology Authors: Lijuan Chong, Yao-Wen Jiang, Dongxu Wang, Pengzhao Chang, Kai Xu and Jingjing Li Tags: Research Source Type: research

Radiotherapy combined with nano-biomaterials for cancer radio-immunotherapy
Radiotherapy (RT) plays an important role in tumor therapy due to its noninvasiveness and wide adaptation. In recent years, radiation therapy has been discovered to induce an anti-tumor immune response, which ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - October 30, 2023 Category: Nanotechnology Authors: Qingrong Dong, Tingyu Xue, Haili Yan, Fang Liu, Ruixue Liu, Kun Zhang, Yu Chong, Jiangfeng Du and Hui Zhang Tags: Review Source Type: research

A carrier-free supramolecular nano-twin-drug for overcoming irinotecan-resistance and enhancing efficacy against colorectal cancer
Irinotecan (Ir) is commonly employed as a first-line chemotherapeutic treatment for colorectal cancer (CRC). However, tremendous impediments remain to be addressed to surmount drug resistance and ameliorate ad... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - October 28, 2023 Category: Nanotechnology Authors: Miaomiao Yuan, Tong Chen, Lu Jin, Peng Zhang, Luoyijun Xie, Shuyi Zhou, Lianfeng Fan, Li Wang, Cai Zhang, Ning Tang, LiHao Guo, Chengmei Xie, Yanhong Duo, Ling Li and Leilei Shi Tags: Research Source Type: research

Superior TRAIL gene expression and cancer cell apoptosis mediated by highly branched-linear poly( β-amino ester)s
Extensive efforts have been dedicated to enhancing the expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in cancer cells for the development of effective cancer treatments. However,... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - October 28, 2023 Category: Nanotechnology Authors: Yitong Zhao, Tao Bo, Chenfei Wang, Dingjin Yao, Chaolan Pan, Weiyi Xu, Hao Zhou, Ming Li and Si Zhang Tags: Research Source Type: research

Novel drug delivery strategies for antidepressant active ingredients from natural medicinal plants: the state of the art
Depression is a severe mental disorder among public health issues. Researchers in the field of mental health and clinical psychiatrists have long been faced with difficulties in slow treatment cycles, high rec... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - October 27, 2023 Category: Nanotechnology Authors: Shun Yuan, Ting Ma, Ya-Nan Zhang, Ning Wang, Zulqarnain Baloch and Ke Ma Tags: Review Source Type: research

TiO2 nanoparticles promote tumor metastasis by eliciting pro-metastatic extracellular vesicles
The development of nanotechnology has provided numerous possibilities for the diagnosis and treatment of cancer. Paradoxically, some in vivo experimental studies have also shown that nanoparticles (NPs) could ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - October 27, 2023 Category: Nanotechnology Authors: Xupeng Mu, Kebang Hu, Anhui Wei, Jinping Bai, Li Feng and Jinlan Jiang Tags: Research Source Type: research